NF ‐E2–Related Factor 2 Regulates Interferon Receptor Expression and Alters Macrophage Polarization in Lupus

Differential responsiveness of monocyte and macrophage subsets to interferon

(2019) Shuhong Han et al.   Arthritis & Rheumatology

Nrf2 activation protects against intratracheal LPS induced mouse/murine acute respiratory distress syndrome by regulating macrophage polarization

(2018) Juan Wei et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The KEAP1-NRF2 System: a Thiol-Based Sensor-Effector Apparatus for Maintaining Redox Homeostasis

(2018) Masayuki Yamamoto et al.   PHYSIOLOGICAL REVIEWS

Liver X Receptor Agonist Therapy Prevents Diffuse Alveolar Hemorrhage in Murine Lupus by Repolarizing Macrophages

(2018) Shuhong Han et al.   Frontiers in Immunology

RPA1 binding to NRF2 switches ARE-dependent transcriptional activation to ARE-NRE–dependent repression

(2018) Pengfei Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Monogenic Lupus: A Developing Paradigm of Disease

(2018) Jessie M. Alperin et al.   Frontiers in Immunology

A Novel Subset of Anti-Inflammatory CD138+Macrophages Is Deficient in Mice with Experimental Lupus

(2017) Shuhong Han et al.   JOURNAL OF IMMUNOLOGY

Pathogenesis of Diffuse Alveolar Hemorrhage in Murine Lupus

(2017) Haoyang Zhuang et al.   Arthritis & Rheumatology

Anifrolumab, an Anti-Interferon-α Receptor Monoclonal Antibody, in Moderate-to-Severe Systemic Lupus Erythematosus

(2017) Richard Furie et al.   Arthritis & Rheumatology

The antioxidant transcription factor Nrf2 contributes to the protective effect of mild thermotolerance (40 °C) against heat shock-induced apoptosis

(2016) Audrey Glory et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription

(2016) Eri H. Kobayashi et al.   Nature Communications

Nrf2 regulates ROS production by mitochondria and NADPH oxidase

(2015) Stjepana Kovac et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Dimethyl fumarate and the oleanane triterpenoids, CDDO-imidazolide and CDDO-methyl ester, both activate the Nrf2 pathway but have opposite effects in the A/J model of lung carcinogenesis

(2015) Ciric To et al.   CARCINOGENESIS

Brusatol provokes a rapid and transient inhibition of Nrf2 signaling and sensitizes mammalian cells to chemical toxicity—implications for therapeutic targeting of Nrf2

(2015) Adedamola Olayanju et al.   FREE RADICAL BIOLOGY AND MEDICINE

The emerging role of Nrf2 in mitochondrial function

(2015) Albena T. Dinkova-Kostova et al.   FREE RADICAL BIOLOGY AND MEDICINE

Application of Mass Spectrometry Profiling to Establish Brusatol as an Inhibitor of Global Protein Synthesis

(2015) Steffan Vartanian et al.   MOLECULAR & CELLULAR PROTEOMICS

The Molecular Signatures Database Hallmark Gene Set Collection

(2015) Arthur Liberzon et al.   Cell Systems

Gene profiling reveals specific molecular pathways in the pathogenesis of atherosclerosis and cardiovascular disease in antiphospholipid syndrome, systemic lupus erythematosus and antiphospholipid syndrome with lupus

(2014) Carlos Perez-Sanchez et al.   ANNALS OF THE RHEUMATIC DISEASES

Structure of the BTB Domain of Keap1 and Its Interaction with the Triterpenoid Antagonist CDDO

(2014) Anne Cleasby et al.   PLoS One

The Nrf2 regulatory network provides an interface between redox and intermediary metabolism

(2014) John D. Hayes et al.   TRENDS IN BIOCHEMICAL SCIENCES

Prevention of Murine Lupus Nephritis by Targeting Multiple Signaling Axes and Oxidative Stress Using a Synthetic Triterpenoid

(2014) Tianfu Wu et al.   Arthritis & Rheumatology

Effects of Pristane Alone or Combined with Chloroquine on Macrophage Activation, Oxidative Stress, and Th1/Th2 Skewness

(2014) Qiufang Ouyang et al.   Journal of Immunology Research

Nrf2 suppresses lupus nephritis through inhibition of oxidative injury and the NF-κB-mediated inflammatory response

(2013) Tao Jiang et al.   KIDNEY INTERNATIONAL

Placebo-Controlled Phase 3 Study of Oral BG-12 or Glatiramer in Multiple Sclerosis

(2012) Robert J. Fox et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Unique Hybrid Renal Mononuclear Phagocyte Activation Phenotype in Murine Systemic Lupus Erythematosus Nephritis

(2011) R. Bethunaickan et al.   JOURNAL OF IMMUNOLOGY

Brusatol enhances the efficacy of chemotherapy by inhibiting the Nrf2-mediated defense mechanism

(2011) D. Ren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer Chemoprevention Mechanisms Mediated Through the Keap1–Nrf2 Pathway

(2010) John D. Hayes et al.   ANTIOXIDANTS & REDOX SIGNALING

Identification of a Novel Macrophage Phenotype That Develops in Response to Atherogenic Phospholipids via Nrf2

(2010) Alexandra Kadl et al.   CIRCULATION RESEARCH

Type I Interferon Modulates Monocyte Recruitment and Maturation in Chronic Inflammation

(2009) Pui Y. Lee et al.   AMERICAN JOURNAL OF PATHOLOGY

Triterpenoids as new promising anticancer drugs

(2009) Alessia Petronelli et al.   ANTI-CANCER DRUGS

Induction of autoimmunity by pristane and other naturally occurring hydrocarbons

(2009) Westley H. Reeves et al.   TRENDS IN IMMUNOLOGY

A mitochondria-targeted nitroxide is reduced to its hydroxylamine by ubiquinol in mitochondria

(2008) Jan Trnka et al.   FREE RADICAL BIOLOGY AND MEDICINE