Article
Biochemistry & Molecular Biology
Schilin Wen, Veronica Iturriaga, Belgica Vasquez, Mariano del Sol
Summary: This study aimed to compare the effects of a single intra-articular infiltration and two infiltrations of medium molecular weight hyaluronic acid of high and low viscosity on the histopathological characteristics of temporomandibular joint osteoarthritis induced in rabbits. The results showed that all treated groups significantly reduced the severity of osteoarthritis, with the group receiving two infiltrations of high viscosity hyaluronic acid showing the best results.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Sinduja Malarkodi Elangovan, S. Muthu Kumar, V. Sindhu, Balaji Mahendiran, Shalini Muthusamy, Gopal Shankar Krishnakumar
Summary: This study focuses on the extraction, purification, and characterization of galactomannan from Borassus labellifer (Linn.) seeds for its potential use in tissue engineering. The isolated galactomannan, known as BFG, showed promising compositional and functional properties. The BFG demonstrated a non-Newtonian and pseudo-plastic behavior, possessed an amorphous structure with the presence of pores and cervices, and exhibited favorable biological activity against fibroblast cells.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Engineering, Biomedical
Rebecca Rothe, Yong Xu, Alvin Kuriakose Thomas, Sebastian Meister, Yixin Zhang, Jens Pietzsch, Sandra Hauser
Summary: This study presents an injectable hydrogel system based on oligopeptides interacting with sulphated polysaccharides, showing high tolerability and biocompatibility in mice. The degradation rate of the hydrogels can be varied by altering components, allowing for sustained release of growth factors.
Article
Chemistry, Applied
Fuxin Xue, Hui Zhang, Junli Hu, Yichun Liu
Summary: The water resistance of electrospun hyaluronic acid (HA) nanofibers was improved by crosslinking with the periodate oxidation - adipic acid dihydrazide (ADH) strategy, allowing for potential applications in biomedical fields such as wound healing, adhesion prevention, and tissue engineering.
CARBOHYDRATE POLYMERS
(2021)
Article
Food Science & Technology
Zhen Yang, Qi Sun, Na Ji, Lei Dai, Liu Xiong, Qingjie Sun
Summary: Starch gelatinization traditionally involves heating starch granules in the presence of moisture, but this study explores gelatinizing starch using a NaOH/glycerol solution at room temperature. Experimental results show that NaOH plays a major role while glycerol functions as an auxiliary in starch gelatinization, which can expand starch applications in food packaging, agricultural, and textile industries with its simple and fast method.
Article
Polymer Science
Yuya Doi, Atsushi Takano, Yoshiaki Takahashi, Yushu Matsushita
Summary: The study found that dumbbell polymers form a unique network structure with distinctive entanglement characteristics in the system. Dumbbell PS samples with longer central chains exhibit slower terminal relaxation and retain entanglement features in high-concentration DOP solutions.
Article
Biochemistry & Molecular Biology
Guillem Ferreres, Silvia Perez-Rafael, Juan Torrent-Burgues, Tzanko Tzanov
Summary: Silver nanoparticles (Ag NPs) are considered promising antimicrobial materials to combat antibiotic resistance. This study found that the molecular weight of hyaluronic acid played a crucial role in the morphology, size, and antibacterial activity of the Ag NPs. Higher molecular weight polymers showed greater interaction with bacteria and better bactericidal effects, while lower molecular weight polymers had reduced antimicrobial efficacy.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Food Science & Technology
Laura Cecilia Gomez Pamies, Maria Mercedes Lataza Rovaletti, Nancy Maria Jimena Martinez Amezaga, Elisa Ines Benitez
Summary: This study proposes the use of pyrodextrins obtained from sorghum to improve the traditional African sorghum beer, enhancing alpha-acid utilization, bitterness, and viscosity of the drink to achieve values similar to typical lager beer obtained from barley. Addition of 10 g/L pyrodextrin resulted in a 4.4% increase in wort viscosity and a 4.9% increase in beer viscosity.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Materials Science, Textiles
Prajesh Nayak, Anup K. Ghosh, Naresh Bhatnagar
Summary: Formation of nano-micron size fibers of UHMWPE can be achieved via high temperature electrospinning. The solution properties and entanglement concentration play crucial roles in determining the morphology of the electrospun fibers. SEM analysis showed that defect-free smooth fibers are obtained when the solution concentration is around 1.5-2.5 times the entanglement concentration.
FIBERS AND POLYMERS
(2022)
Review
Biochemistry & Molecular Biology
Aditya Kaul, Walker D. Short, Xinyi Wang, Sundeep G. Keswani
Summary: This article discusses the important role of hyaluronidases in human tissues, especially in promoting disease progression, and the potential benefits as clinical treatments currently and in the future.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Chemistry, Applied
Zhiqing Tian, Fan Jiang, Haolong Cong, Shuifang Zhu
Summary: A gel permeation chromatography (GPC) method calibrated based on serrated peaks in chromatograms was developed to determine the molecular weight (MW) of low molecular weight (LWM) hyaluronic acid (HA) and chondroitin sulfate (CS). The method was validated using enzymolysis-based MW calibrants and showed high correlation coefficients in the standard curves. Measurement of a sample could be conducted in less than 30 minutes with minuscule discrepancies in MW values. The method was also capable of measuring very low MWs.
CARBOHYDRATE POLYMERS
(2023)
Article
Chemistry, Physical
Madison Lasich, Victoria T. Adeleke
Summary: Biologically active estrogenic hormones with endocrine disrupting effects have been found in water effluent. Developing cost-effective and reliable extraction methods is important for pollutant detection and environmental remediation.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Engineering, Chemical
Ning Li, Hao Ma, Tongyu Wang, Caixia Sun, Shuqian Xia
Summary: In this study, a new salt-resistant water-soluble viscosity reducer was designed and synthesized, which showed excellent viscosity-reducing properties for heavy oil under highly mineralized formation water and high-temperature reservoir conditions. The thermal stability, hydrophobicity, surface activity, and salt resistance of the polymer improved with increasing molecular weight. The study also discussed the viscosity reduction mechanism of different molecular weight viscosity reducers.
JOURNAL OF THE TAIWAN INSTITUTE OF CHEMICAL ENGINEERS
(2023)
Article
Polymer Science
Yexiao Duan, Yanran Zhao, Shili Ai, Dong Qiu, Xiaoyan Wang, Xiaozhong Qu, Zhenzhong Yang
Summary: A new method for processing high-performance plastic composite hydrogels is proposed, which involves the incorporation of a thixotropic fluid and adjustment of interpolymer interactions. The resulting hydrogels have a high compressive modulus and can be processed into desired shapes.
Article
Polymer Science
Francoise Berzin, Bruno Vergnes
Summary: This study demonstrates that the viscous behavior of polypropylene materials can be accurately described using the time/molecular weight superposition method, significantly reducing the number of parameters to be considered.
Article
Nanoscience & Nanotechnology
Muhammad Ahmad Bkkar, Roman Olegovich Olekhnovich, Arina Valerievna Kremleva, Yakov Nikolaevich Kovach, Victoria Kalanchina, Mayya Valerievna Uspenskaya
Summary: Polymer-perovskite nanofibers were prepared by electrospinning and annealing, with controllable diameter by adjusting various parameters. Stable NCs formation can be achieved at lower annealing temperatures, and the size of crystals and complexation with PVP contribute to the stability of nanofibers.
APPLIED NANOSCIENCE
(2022)
Article
Polymer Science
Muhammad Bkkar, Roman Olekhnovich, Arina Kremleva, Vera Sitnikova, Yakov Kovach, Nikolai Zverkov, Mayya Uspenskaya
Summary: Optimizing the properties of electrospun polymer-perovskite nanofibers is crucial for enhancing the performance of flexible optoelectronic devices. The study investigates the effects of electrospinning setup parameters on various properties of modified polyvinylpyrrolidone nanofibers, including their external structure, perovskite crystallinity, optical properties, thermal properties, shrinkage ratio, mechanical properties, and long-term stability. The results demonstrate that the structure of nanofibers depends on the electrical voltage, collector rotation speed, and process duration. Increasing the electrical voltage or/and the process time improves the perovskite crystallinity and light absorption. The polymer's glass transition temperature is influenced by the embedded perovskite and the collector's rotation speed. The shrinkage ratio and mechanical properties of the nanofibers are controlled by the rotation speed and electrical voltage. The nanofibers exhibit the best mechanical properties with a rotary collector at a rotational speed of 500-750 rpm. They also demonstrate good long-term stability and high thermal stability, with the long-term stability being inversely proportional to the electrical voltage value.
Review
Biochemistry & Molecular Biology
Collins N. Elangwe, Svetlana N. Morozkina, Roman O. Olekhnovich, Victoria O. Polyakova, Alexander Krasichkov, Piotr K. Yablonskiy, Mayya V. Uspenskaya
Summary: Wound healing is a complex process aimed at creating new tissues and restoring anatomical functions. Wound dressings, made from natural or synthetic biomaterials, play a crucial role in protecting the wound and accelerating healing. Polysaccharide polymers, particularly pullulan, have gained attention for their non-toxic, antibacterial, biocompatible, hemostatic, and nonimmunogenic properties. Hydrogels based on pullulan have shown promise as wound dressings due to their high water retention capacity, which creates a moist environment and promotes wound healing. The incorporation of pullulan with other biocompatible polymers, such as chitosan and gelatin, has been explored to enhance its properties for wound dressing applications.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemical Research Methods
Boris Y. Karas, Vera E. Sitnikova, Tatiana N. Nosenko, Vladimir G. Dedkov, Natalia A. Arsentieva, Natalia V. Gavrilenko, Ivan S. Moiseev, Areg A. Totolian, Andrey V. Kajava, Mayya V. Uspenskaya
Summary: The development of fast, cheap, and reliable methods for determining seroconversion is crucial. In the context of the COVID-19 pandemic, it is important to study the rate of immune layer formation in different populations and post-vaccination immunity. Attenuated total reflection Fourier transform infrared spectroscopy combined with machine learning was investigated for detecting seroconversion against SARS-CoV-2. The study found clear spectral differences in plasma samples of recovered COVID-19 patients and healthy donors, and achieved high accuracy in identifying specimens using this method.
JOURNAL OF BIOPHOTONICS
(2023)
Article
Polymer Science
Muhammad A. Bkkar, Roman O. Olekhnovich, Arina V. Kremleva, Vera E. Sitnikova, Yakov N. Kovach, Nikolai A. Zverkov, Mayya V. Uspenskaya
Summary: The properties of electrospun polyvinylpyrrolidone-cesium lead iodide (CsPbI3) nanofibers were optimized by controlling the solution concentration. Increasing polymer concentration led to larger nanofiber diameter, while reducing total material concentration resulted in smaller nanofiber diameter. By altering the solution concentration, maximum perovskite crystallinity and improved optical properties were achieved. The resulting nanofibers showed high thermal stability with minimal weight loss at elevated temperatures.
JOURNAL OF POLYMER RESEARCH
(2023)
Article
Polymer Science
Rigel Antonio Olvera Bernal, Roman Olegovich Olekhnovich, Mayya Valerievna Uspenskaya
Summary: Chitosan/PVA nanofibrous electroresponsive soft actuators were successfully prepared using electrospinning, exhibiting rapid displacement under acidic conditions. Chitosan/PVA nanofibers were characterized and electroactive response was evaluated. The bending speed displacement of the nanofibers showed a correlation with chitosan content and pH, with the highest speed displacement (1.86 mm(-1)) observed in a pH 3 sample with 4 wt.% chitosan content. The proportion of free amine groups, determined by deconvoluting the FTIR spectra, increased with higher chitosan content, with percentages of 3.6% and 4.59% for nanofibers containing 2.5 wt.% and 4 wt.% chitosan, respectively.
Article
Engineering, Multidisciplinary
Nguyen Hong Thanh, Roman Olekhnovich, Vera Sitnikova, Arina Kremleva, Petr Snetkov, Mayya Uspenskaya
Summary: A nanofiber mat based on PHB/PEG with varying PEG contents was successfully prepared through electrospinning. The thermal and mechanical properties of the PHB/PEG nanofiber mat were investigated, and it was characterized using several analytical techniques. The results showed that increasing the PEG content had a significant effect on the diameter and tensile strength of the nanofibers. The addition of PEG also improved the mechanical properties, hydrophobicity, porosity, and thermal stability of the PHB fiber mat, demonstrating its potential for air or water filtration applications.
Review
Biochemistry & Molecular Biology
Natalia Linkova, Anastasiia Diatlova, Yulia Zinchenko, Anastasiia Kornilova, Petr Snetkov, Svetlana Morozkina, Dmitrii Medvedev, Alexandr Krasichkov, Victoria Polyakova, Piotr Yablonskiy
Summary: This article summarizes the models for the clinical and histological manifestations of sarcoidosis and discusses the potential applications of quantum dots in molecular diagnostics.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Polymer Science
Rigel Antonio Olvera Bernal, Roman O. Olekhnovich, Mayya V. Uspenskaya
Summary: This study presents a comprehensive investigation on the influence of pre- and post-fabrication parameters on the electroactive properties of electrospun chitosan/PVA-based micro- and nanofibers. The thermal treatment improved the stability and electroactive response of all fiber samples.
