Development of a polygenic risk score to improve screening for fracture risk: A genetic risk prediction study

Clinical use of current polygenic risk scores may exacerbate health disparities

(2019) Alicia R. Martin et al.   NATURE GENETICS

Polygenic Prediction of Weight and Obesity Trajectories from Birth to Adulthood

(2019) Amit V. Khera et al.   CELL

Has the Genome Granted Our Wish Yet?

(2019) David J. Hunter et al.   NEW ENGLAND JOURNAL OF MEDICINE

Screening for Osteoporosis to Prevent Fractures

(2018) et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

The Cost-Effectiveness of Screening in the Community to Reduce Osteoporotic Fractures in Older Women in the UK: Economic Evaluation of the SCOOP Study

(2018) David A Turner et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Screening in the community to reduce fractures in older women (SCOOP): a randomised controlled trial

(2018) Lee Shepstone et al.   LANCET

Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts

(2018) Tyler M Seibert et al.   BMJ-British Medical Journal

Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts

(2018) Tyler M Seibert et al.   BMJ-British Medical Journal

Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations

(2018) Amit V. Khera et al.   NATURE GENETICS

Identification of 613 new loci associated with heel bone mineral density and a polygenic risk score for bone mineral density, osteoporosis and fracture

(2018) Stuart K. Kim   PLoS One

An atlas of genetic influences on osteoporosis in humans and mice

(2018) John A. Morris et al.   NATURE GENETICS

Identification of 153 new loci associated with heel bone mineral density and functional involvement of GPC6 in osteoporosis

(2017) John P Kemp et al.   NATURE GENETICS

UK clinical guideline for the prevention and treatment of osteoporosis

(2017) J. Compston et al.   Archives of Osteoporosis

External validation of clinical prediction models using big datasets from e-health records or IPD meta-analysis: opportunities and challenges

(2016) Richard D Riley et al.   BMJ-British Medical Journal

External validation of clinical prediction models using big datasets from e-health records or IPD meta-analysis: opportunities and challenges

(2016) Richard D Riley et al.   BMJ-British Medical Journal

A systematic review of intervention thresholds based on FRAX

(2016) John A. Kanis et al.   Archives of Osteoporosis

Efficient Bayesian mixed-model analysis increases association power in large cohorts

(2015) Po-Ru Loh et al.   NATURE GENETICS

Limited Clinical Utility of a Genetic Risk Score for the Prediction of Fracture Risk in Elderly Subjects

(2014) Joel Eriksson et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Clinician’s Guide to Prevention and Treatment of Osteoporosis

(2014) F. Cosman et al.   OSTEOPOROSIS INTERNATIONAL

Cost-Effectiveness of Different Screening Strategies for Osteoporosis in Postmenopausal Women

(2013) Smita Nayak et al.   ANNALS OF INTERNAL MEDICINE

Osteoporosis epidemiology in UK Biobank: a unique opportunity for international researchers

(2013) N. C. Harvey et al.   OSTEOPOROSIS INTERNATIONAL

Genome-wide meta-analysis identifies 56 bone mineral density loci and reveals 14 loci associated with risk of fracture

(2012) Karol Estrada et al.   NATURE GENETICS

Erratum: Genetics of osteoporosis from genome-wide association studies: advances and challenges

(2012) J. Brent Richards et al.   NATURE REVIEWS GENETICS

Mining electronic health records: towards better research applications and clinical care

(2012) Peter B. Jensen et al.   NATURE REVIEWS GENETICS

A comparison of case-finding strategies in the UK for the management of hip fractures

(2012) H. Johansson et al.   OSTEOPOROSIS INTERNATIONAL

UK Biobank: Current status and what it means for epidemiology

(2012) Naomi Allen et al.   Health Policy and Technology

Strengthening the Reporting of Genetic Risk Prediction Studies: The GRIPS Statement

(2011) A. Cecile J. W. Janssens et al.   PLOS MEDICINE

2010 clinical practice guidelines for the diagnosis and management of osteoporosis in Canada: summary

(2010) A. Papaioannou et al.   CANADIAN MEDICAL ASSOCIATION JOURNAL

Harnessing the information contained within genome-wide association studies to improve individual prediction of complex disease risk

(2009) David M. Evans et al.   HUMAN MOLECULAR GENETICS

FRAX™ and the assessment of fracture probability in men and women from the UK

(2008) J. A. Kanis et al.   OSTEOPOROSIS INTERNATIONAL