Differential expression of Cdk5-phosphorylated CRMP2 following a spared nerve injury

Dysregulation of CRMP2 Post-Translational Modifications Drive Its Pathological Functions

(2019) Aubin Moutal et al.   MOLECULAR NEUROBIOLOGY

Cdk5-dependent phosphorylation of Cav3.2 T-type channels: possible role in nerve ligation-induced neuropathic allodynia and the compound action potential in primary afferent C-fibers

(2019) Kimberly Gomez et al.   JOURNAL OF NEUROSCIENCE

The Genetics of Neuropathic Pain from Model Organisms to Clinical Application

(2019) Margarita Calvo et al.   NEURON

CRMP2–Neurofibromin Interface Drives NF1-related Pain

(2018) Aubin Moutal et al.   NEUROSCIENCE

Molecular Architecture of the Mouse Nervous System

(2018) Amit Zeisel et al.   CELL

Phosphorylated CRMP2 Regulates Spinal Nociceptive Neurotransmission

(2018) Jie Yu et al.   MOLECULAR NEUROBIOLOGY

CRMP2 Phosphorylation Drives Glioblastoma Cell Proliferation

(2017) Aubin Moutal et al.   MOLECULAR NEUROBIOLOGY

Dissecting the role of the CRMP2–neurofibromin complex on pain behaviors

(2017) Aubin Moutal et al.   PAIN

CRISPR/Cas9 editing of Nf1 gene identifies CRMP2 as a therapeutic target in neurofibromatosis type 1-related pain that is reversed by (S)-Lacosamide

(2017) Aubin Moutal et al.   PAIN

Probing the lithium-response pathway in hiPSCs implicates the phosphoregulatory set-point for a cytoskeletal modulator in bipolar pathogenesis

(2017) Brian T. D. Tobe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

(S)-lacosamide inhibition of CRMP2 phosphorylation reduces postoperative and neuropathic pain behaviors through distinct classes of sensory neurons identified by constellation pharmacology

(2016) Aubin Moutal et al.   PAIN

(S)-Lacosamide Binding to Collapsin Response Mediator Protein 2 (CRMP2) Regulates CaV2.2 Activity by Subverting Its Phosphorylation by Cdk5

(2015) Aubin Moutal et al.   MOLECULAR NEUROBIOLOGY

A membrane-delimited N-myristoylated CRMP2 peptide aptamer inhibits CaV2.2 trafficking and reverses inflammatory and postoperative pain behaviors

(2015) Liberty François-Moutal et al.   PAIN

Epigenetic upregulation of Cdk5 in the dorsal horn contributes to neuropathic pain in rats

(2014) Kai Li et al.   NEUROREPORT

Surgical Incision-Induced Nociception Causes Cognitive Impairment and Reduction in Synaptic NMDA Receptor 2B in Mice

(2013) X. Zhang et al.   JOURNAL OF NEUROSCIENCE

Suppression of inflammatory and neuropathic pain by uncoupling CRMP-2 from the presynaptic Ca2+ channel complex

(2011) Joel M Brittain et al.   NATURE MEDICINE

The Cdk5 Kinase Downregulates ATP-Gated Ionotropic P2X3 Receptor Function Via Serine Phosphorylation

(2009) Asha Nair et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Neurofibromatosis Type 1 (NF1) Tumor Suppressor, Neurofibromin, Regulates the Neuronal Differentiation of PC12 Cells via Its Associating Protein, CRMP-2

(2008) Siriporn Patrakitkomjorn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY