Article
Materials Science, Ceramics
I. Anila, B. B. Lahiri, Subin P. John, M. Jacob Mathew, John Philip
Summary: This study investigates the AC induction heating properties of colloidal nano-aggregates of ferrimagnetic cobalt ferrite magnetic nanoparticles (MNPs). CoFe2O4 MNPs coated with bio-compatible chitosan polymer were synthesized using co-precipitation. The presence of chitosan coating was confirmed by various spectroscopy studies. The MNPs exhibited ferrimagnetic behavior at room temperature, and the CP-CHN sample showed significantly high AC induction heating efficiency. The cobalt ferrite nano-aggregates have potential applications in magnetic hyperthermia due to their high heating efficiency and bio-compatibility.
CERAMICS INTERNATIONAL
(2023)
Article
Chemistry, Physical
Renpeng Yang, Xiaogang Yu, Heng Li, Chao Wang, Chengwei Wu, Wei Zhang, Weihong Guo
Summary: Mg2+ substitution can increase the Curie temperature and specific saturation magnetization of the nanoparticles within a certain range, leading to improved heating efficiency and low cytotoxicity.
JOURNAL OF ALLOYS AND COMPOUNDS
(2021)
Article
Chemistry, Multidisciplinary
O. M. Lemine, Saja Algessair, Nawal Madkhali, Basma Al-Najar, Kheireddine El-Boubbou
Summary: This study reports the self-heating mechanisms of magnetite nanoparticles (MNPs) prepared by the Ko-precipitation Hydrolytic Basic (KHB) method. The MNPs exhibit favorable heating responses under magnetic excitation, making them promising candidates for magnetically triggered biomedical hyperthermia applications.
Article
Chemistry, Physical
Saso Gyergyek, Elena Chernyshova, Katalin Boor, Marijan Necemer, Darko Makovec
Summary: In this study, magnetic carbon nanocomposites were prepared by carbothermal reduction of iron-oxide nanoparticles. These nanocomposites exhibit ferromagnetic behavior and consist of Fe/Fe3C nanoparticles encapsulated in a graphitic shell. The graphitic shell prevents the oxidation of the Fe nanoparticles and maintains their magnetic properties.
JOURNAL OF ALLOYS AND COMPOUNDS
(2023)
Article
Chemistry, Physical
M. Xing, Jeotikanta Mohapatra, J. Beatty, J. Elkins, Nil Kanatha Pandey, A. Chalise, W. Chen, M. Jin, J. Ping Liu
Summary: Localized heat generation using iron carbide nanoparticles with a thin carbon shell shows promising magnetothermal and photothermal effects when irradiated with a NIR laser, and exhibits enhanced specific absorption rate under an alternating magnetic field due to high magnetization and coercivity.
JOURNAL OF ALLOYS AND COMPOUNDS
(2021)
Article
Nanoscience & Nanotechnology
Idoia Castellanos-Rubio, Ander Baron, Oier Luis-Lizarraga, Irati Rodrigo, Izaskun Gil de Muro, Inaki Orue, Virginia Martinez-Martinez, Ainara Castellanos-Rubio, Fernando Lopez-Arbeloa, Maite Insausti
Summary: Nanosystems containing both fluorescent and magnetic modules have great potential in biomedical applications. In this study, a magneto-luminescent system based on Fe3O4 nanoparticles and thermosensitive rhodamine fluorophores was designed, which can self-monitor the degree of hyperthermia. The optimized nanoparticles show suitable fluorescence thermosensitivity and excellent heating capacity within the clinical safety limits, opening up promising avenues for next-generation medical technologies.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Physics, Condensed Matter
Krishna Priya Hazarika, Rushikesh Fopase, Lalit M. Pandey, J. P. Borah
Summary: This research aims to enhance the heating efficiency of Fe3O4 nanoparticles by doping Gd in the matrix, making it a potential candidate for magnetic hyperthermia applications.
PHYSICA B-CONDENSED MATTER
(2022)
Article
Chemistry, Multidisciplinary
Joana Goncalves, Claudia Nunes, Liliana Ferreira, Maria Margarida Cruz, Helena Oliveira, Veronica Bastos, Alvaro Mayoral, Qing Zhang, Paula Ferreira
Summary: Fucoidan-coated magnetite nanoparticles exhibit great potential for magnetic hyperthermia therapy, showing high specific loss power and intrinsic loss power values while maintaining biocompatibility, meeting the required criteria for MHT application.
Article
Chemistry, Physical
Daniel J. Rosen, Shengsong Yang, Emanuele Marino, Zhiqiao Jiang, Christopher B. Murray
Summary: This study improves the understanding of heating in inductively coupled systems by using extended X-ray absorption fine structure spectroscopy in conjunction with thermal imaging. The temperature of inductively heated nanocrystals is obtained from the correlated Debye model. Testing nanostructured systems as unattached nanocrystals and heterodimers, significant temperature differences of up to 73.60 degrees C compared to their local support environment are reported.
JOURNAL OF PHYSICAL CHEMISTRY C
(2022)
Article
Biophysics
Hailei Lin, Liangliang Yin, Beidong Chen, Yanqin Ji
Summary: Nanomaterials, especially magnetic nanoparticles (MNPs), have great potential for cancer treatment due to their unique properties. In this study, Fe3O4@SiO2@Sec(2)@FA nanoparticles were designed as a novel nano-radiosensitizer to enhance the therapeutic effects of radiotherapy. These nanoparticles exhibited good heat generation efficiency and active targeting, making them suitable for magnetic hyperthermia/radiotherapy.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Physics, Condensed Matter
A. Gangwar, S. K. Alla, N. K. Prasad
Summary: The study demonstrated that citrate capped ZrxFe3-xO4 based magnetic ferrofluids exhibit good biocompatibility with human lung adenocarcinoma cells, making them promising for applications in magnetic hyperthermia. These ferrofluids showed high specific absorption rate and suitable biocompatibility characteristics.
PHYSICA B-CONDENSED MATTER
(2021)
Article
Biochemistry & Molecular Biology
Arkadiusz Jozefczak, Katarzyna Kaczmarek, Rafal Bielas, Jitka Prochazkova, Ivo Safarik
Summary: Magneto-responsive textiles have recently gained importance in various fields, including biomedical engineering. Most research has focused on single magnetic fibers and physical characterization of magnetic textiles. In this study, we engineered materials with magnetic properties from simple woven and non-woven textiles, which can potentially be used as a smart magnetic platform for heating treatments. Experiments showed that the temperature increase in tissue-mimicking phantoms depended on factors such as the type of textile material, concentration of magnetic nanoparticles, and number of layers covering the phantom. The achieved temperature elevation with magnetic textiles is sufficient for potential applications in magnetic hyperthermia therapies and heating patches or bandages.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Multidisciplinary
Milos Ognjanovic, Zeljko Jacimovic, Milica Kosovic-Perutovic, Irina Besu Zizak, Tatjana Stanojkovic, Zeljko Zizak, Biljana Dojcinovic, Dalibor M. Stankovic, Bratislav Antic
Summary: Partial cation substitution can change the physical properties of compounds, and in this study, yttrium-substituted iron oxide nanoconstructs (YIONs) were prepared. The Y3+ substitution in maghemite (γ-Fe2O3) crystal structures was limited to 1.5%. The YIONs showed excellent heating efficiency and low toxicity, making them suitable for potential medical and technological applications such as magnetic hyperthermia cancer treatment and catalysis.
Article
Chemistry, Physical
Takahiro Takekiyo, Natsuki Yamada, Taku Amo, Atsushi Asano, Yukihiro Yoshimura
Summary: This article investigates the application of magnetic nano-clusters (MNCs) in magnetic fluid hyperthermia (MFH) therapy and studies the effect of MNC size on the therapeutic efficiency by adjusting the surfactant concentration. The experimental results show that the efficiency of MFH can be enhanced by reducing the surfactant concentration.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Chemistry, Physical
Molongnenla Jamir, Riyajul Islam, Lalit M. Pandey, J. P. Borah
Summary: The effect of surface functionalization on Fe3O4 assembled nanoclusters with biopolymers was studied. The results showed that surface functionalization significantly enhanced specific absorption rate, indicating potential for hyperthermia applications.
JOURNAL OF ALLOYS AND COMPOUNDS
(2021)
Article
Construction & Building Technology
P. Leiva-Padilla, F. Moreno-Navarro, G. R. Iglesias, M. C. Rubio-Gamez
Summary: Heavy snowfall is a major hindrance to road transportation during winter. Traditional snow removal methods using de-icing salts are damaging to the environment. This study explores the use of electroconductive asphalt mortars as an environmentally friendly alternative. It demonstrates that road temperature can be controlled using time-varying magnetic fields, providing a functional solution for snowy winters.
ROAD MATERIALS AND PAVEMENT DESIGN
(2022)
Article
Chemistry, Multidisciplinary
Felisa Reyes-Ortega, Angel Delgado, Guillermo R. Iglesias
Summary: The use of magnetic nanoparticles in hyperthermia is gaining interest due to its non-invasive and side effects-free nature. Different shapes of nanoparticles were prepared using a hydrothermal synthesis route, demonstrating superparamagnetic nature and high heating power in hyperthermia applications.
Article
Polymer Science
Mariano Ortega-Munoz, Simona Plesselova, Angel Delgado, Francisco Santoyo-Gonzalez, Rafael Salto-Gonzalez, Maria Dolores Giron-Gonzalez, Guillermo R. Iglesias, Francisco Javier Lopez-Jaramillo
Summary: Magnetite nanoparticles coated with branched poly (ethylene-imine) were synthesized in one pot, with different molecular weights of PEI resulting in four types of particles. These particles were evaluated for hyperthermia and cytotoxicity, with MNP-4 showing promising results in high expressing folate receptor cells.
Article
Chemistry, Multidisciplinary
Federica Vurro, Ylenia Jabalera, Silvia Mannucci, Giulia Glorani, Alberto Sola-Leyva, Marco Gerosa, Alessandro Romeo, Maria Grazia Romanelli, Manuela Malatesta, Laura Calderan, Guillermo R. Iglesias, Maria P. Carrasco-Jimenez, Concepcion Jimenez-Lopez, Massimiliano Perduca
Summary: MamC-expressed BMNPs have advantages in stable functionalization and molecule release, but face challenges in cell internalization. Encapsulation with PLGA and functionalization with TAT peptide enhance internalization without compromising cell viability.
Article
Pharmacology & Pharmacy
Ylenia Jabalera, Alberto Sola-Leyva, Maria P. Carrasco-Jimenez, Guillermo R. Iglesias, Concepcion Jimenez-Lopez
Summary: The study shows that MamC-mediated BMNPs have the potential to increase temperature under near-infrared laser irradiation as a magnetic hyperthermia agent. Furthermore, the synergy between photothermia and chemotherapy using doxorubicin-functionalized BMNPs has shown effectiveness against tumor cells in vitro experiments.
Article
Polymer Science
Manuel Quesada-Perez, Jose-Alberto Maroto-Centeno, Maria del Mar Ramos-Tejada, Alberto Martin-Molina
Summary: This work computes the longtime diffusion of a solute in a chemically crosslinked and flexible hydrogel using a coarse-grained model of a polymeric network. The relevance of chain flexibility becomes important when the polymer volume fraction and the solute size increase. The results show that solute particles can moderately diffuse in flexible hydrogels even when their diameter is comparable to the mesh size. The diffusion coefficients obtained here are in good agreement with previously reported experimental data, without the need for any adjustable parameter.
Article
Nanoscience & Nanotechnology
Yu Xiao, Kartikey Pandey, Alba Nicolas-Boluda, Delphine Onidas, Philippe Nizard, Florent Carn, Theotim Lucas, Jerome Gateau, Alberto Martin-Molina, Manuel Quesada-Perez, Maria del Mar Ramos-Tejada, Florence Gazeau, Yun Luo, Claire Mangeney
Summary: Smart microgels made of polymeric particles doped with inorganic nanoparticles have promising potential in nanomedicine applications. This study presents an innovative modular strategy for the rational design of well-defined and densely filled hybrid particles. The resulting hybrid particles exhibit unique properties and show potential in various biomedical applications.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Polymer Science
Sergio Martin-Martin, Maria del Mar Ramos-Tejada, Antonio Rubio-Andres, Ana B. Bonhome-Espinosa, Angel Delgado, Maria L. Jimenez
Summary: Brownian diffusion is used to determine the rheological properties of complex media, but the behavior of tracer particles is influenced by various phenomena related to the dynamics of the particles and polymer coils. The characteristics of the dispersed entities, depletion phenomena, and sticking conditions affect the translational diffusion of probes. The retardation effect of the host fluid on the rotational diffusion of nonspherical particles is not well understood.
Article
Polymer Science
Marina Lazaro, Pablo Lupianez, Jose L. Arias, Maria P. Carrasco-Jimenez, Angel Delgado, Guillermo R. Iglesias
Summary: This study investigates the synthesis and applications of magnetite nanorods (MNRs) in magnetic hyperthermia, photothermia, and drug release. The results show that the MNRs exhibit high monodispersity and consistent shape, and their photothermia response can be improved by controlling the parameters of external fields. By coating the MNRs with a layer of gold and polyethyleneimine (PEI), the efficiency of MNRs in magnetic hyperthermia and photothermia treatments can be enhanced. Furthermore, the study confirms the non-cytotoxicity of MNRs to human cells and demonstrates their ability to release drugs at a faster rate.
Article
Polymer Science
Manuel Quesada-Perez, Luis Perez-Mas, David Carrizo-Tejero, Jose-Alberto Maroto-Centeno, Maria del Mar Ramos-Tejada, Alberto Martin-Molina
Summary: The release of drugs in flexible nanogels is influenced by the initial drug distribution, and surface phenomena driven by steric interactions can result in counterintuitive behaviors. These findings have implications for understanding drug release kinetics and interpreting release curves.
Article
Pharmacology & Pharmacy
Salvatore Calogero Gaglio, Ylenia Jabalera, Manuel Montalban-Lopez, Ana Cristina Millan-Placer, Marina Lazaro-Callejon, Mercedes Maqueda, Maria Paz Carrasco-Jimenez, Alejandro Laso, Jose A. Ainsa, Guillermo R. Iglesias, Massimiliano Perduca, Concepcion Jimenez Lopez
Summary: The nano-assembly coupling antimicrobial peptide AS-48 with biomimetic magnetic nanoparticles has shown potent bactericidal effects on both Gram-positive and Gram-negative bacteria when combined with magnetic hyperthermia. However, treating intracellular pathogens remains challenging, and improving the cellular uptake of the nanocarrier is crucial for successful treatment.
Article
Chemistry, Physical
Sergio Orozco-Barrera, Guillermo R. Iglesias, angel V. Delgado, Sergio Garcia-Larios, Silvia Ahualli
Summary: In recent years, the importance of obtaining, reusing, or purifying water has increased significantly. Capacitive deionization (CDI) method based on electric double layer (EDL) concept has been considered as a potential solution for ion adsorption from water. This study explores the effect of a coating technique known as layer-by-layer (LbL) on the efficiency of the CDI process. It was found that the number of polyelectrolyte layers and the porosity of the carbon electrodes play a significant role in the ion adsorption and process efficiency.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2023)
Article
Physics, Fluids & Plasmas
F. Carrique, E. Ruiz-Reina, F. J. Arroyo, M. L. Jimenez, S. Ahualli, A. Delgado
Summary: A general model is developed to study the electrokinetics and dielectric response of a concentrated salt-free colloid, taking into account the finite size of the counterions released by the particles. The effects of counterion finite size are investigated using a hard-sphere model approach. The study provides insights on the importance of counterion finite-size effects for the electrokinetic and dielectric properties of highly charged and concentrated colloids.