May the Force Be With You: The Light and Dark Sides of the Microbiota–Gut–Brain Axis in Neuropsychiatry

Microbial Reconstitution Reverses Maternal Diet-Induced Social and Synaptic Deficits in Offspring

(2016) Shelly A. Buffington et al.   CELL

Gut Commensal E. coli Proteins Activate Host Satiety Pathways following Nutrient-Induced Bacterial Growth

(2016) Jonathan Breton et al.   Cell Metabolism

A gut (microbiome) feeling about the brain

(2016) Eoin Sherwin et al.   CURRENT OPINION IN GASTROENTEROLOGY

FODMAPs alter symptoms and the metabolome of patients with IBS: a randomised controlled trial

(2016) Keith McIntosh et al.   GUT

Growing up in a Bubble: Using Germ-Free Animals to Assess the Influence of the Gut Microbiota on Brain and Behavior

(2016) Pauline Luczynski et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Magnetic resonance spectroscopy reveals oral Lactobacillus promotion of increases in brain GABA, N-acetyl aspartate and glutamate

(2016) Rafal Janik et al.   NEUROIMAGE

Clinical and metabolic response to probiotic administration in patients with major depressive disorder: A randomized, double-blind, placebo-controlled trial

(2016) Ghodarz Akkasheh et al.   NUTRITION

Autoimmune diseases, gastrointestinal disorders and the microbiome in schizophrenia: more than a gut feeling

(2016) Emily G. Severance et al.   SCHIZOPHRENIA RESEARCH

Intestinal microbiome is related to lifetime antibiotic use in Finnish pre-school children

(2016) Katri Korpela et al.   Nature Communications

Mood by microbe: towards clinical translation

(2016) Timothy G. Dinan et al.   Genome Medicine

Mast Cells and Irritable Bowel Syndrome: From the Bench to the Bedside

(2016) Lei Zhang et al.   Journal of Neurogastroenterology and Motility

Regulation of prefrontal cortex myelination by the microbiota

(2016) A E Hoban et al.   Translational Psychiatry

Administration of Non-Absorbable Antibiotics to Pregnant Mice to Perturb the Maternal Gut Microbiota Is Associated with Alterations in Offspring Behavior

(2016) Shiro Tochitani et al.   PLoS One

Influence of galacto-oligosaccharide mixture (B-GOS) on gut microbiota, immune parameters and metabonomics in elderly persons

(2015) Jelena Vulevic et al.   BRITISH JOURNAL OF NUTRITION

Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis

(2015) Jessica M. Yano et al.   CELL

Regulation of energy balance by a gut–brain axis and involvement of the gut microbiota

(2015) Paige V. Bauer et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The impact of gut microbiota on brain and behaviour

(2015) Timothy G. Dinan et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Probiotics Improve Inflammation-Associated Sickness Behavior by Altering Communication between the Peripheral Immune System and the Brain

(2015) C. D'Mello et al.   JOURNAL OF NEUROSCIENCE

Bacterial Community Structure Associated With Elective Cesarean Section Versus Vaginal Delivery in Chinese Newborns

(2015) Dong Liu et al.   JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION

Host microbiota constantly control maturation and function of microglia in the CNS

(2015) Daniel Erny et al.   NATURE NEUROSCIENCE

Microbiota and neuroimmune signalling—Metchnikoff to microglia

(2015) John F. Cryan et al.   Nature Reviews Gastroenterology & Hepatology

Enteroendocrine cells: a review of their role in brain-gut communication

(2015) R. Latorre et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Birth by Caesarean Section and the Risk of Adult Psychosis: A Population-Based Cohort Study

(2015) Sinéad M. O’Neill et al.   SCHIZOPHRENIA BULLETIN

Metagenomic Sequencing Indicates That the Oropharyngeal Phageome of Individuals With Schizophrenia Differs From That of Controls

(2015) Robert H. Yolken et al.   SCHIZOPHRENIA BULLETIN

Breaking down the barriers: the gut microbiome, intestinal permeability and stress-related psychiatric disorders

(2015) John R. Kelly et al.   Frontiers in Cellular Neuroscience

Microbiota and host determinants of behavioural phenotype in maternally separated mice

(2015) G. De Palma et al.   Nature Communications

Gastroenterology Issues in Schizophrenia: Why the Gut Matters

(2015) Emily G. Severance et al.   Current Psychiatry Reports

Lactobacillus fermentumNS9 restores the antibiotic induced physiological and psychological abnormalities in rats

(2015) T. Wang et al.   Beneficial Microbes

Probiotics normalize the gut-brain-microbiota axis in immunodeficient mice

(2014) Carli J. Smith et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Altered brain-gut axis in autism: Comorbidity or causative mechanisms?

(2014) Emeran A. Mayer et al.   BIOESSAYS

Altering the Intestinal Microbiota during a Critical Developmental Window Has Lasting Metabolic Consequences

(2014) Laura M. Cox et al.   CELL

Microbiota-Generated Metabolites Promote Metabolic Benefits via Gut-Brain Neural Circuits

(2014) Filipe De Vadder et al.   CELL

The Melanocortin-4 Receptor Is Expressed in Enteroendocrine L Cells and Regulates the Release of Peptide YY and Glucagon-like Peptide 1 In Vivo

(2014) Brandon L. Panaro et al.   Cell Metabolism

Histone acetylation in astrocytes suppresses GFAP and stimulates a reorganization of the intermediate filament network

(2014) Regina Kanski et al.   JOURNAL OF CELL SCIENCE

Gut Vagal Afferents Differentially Modulate Innate Anxiety and Learned Fear

(2014) M. Klarer et al.   JOURNAL OF NEUROSCIENCE

Chronic Functional Bowel Syndrome Enhances Gut-Brain Axis Dysfunction, Neuroinflammation, Cognitive Impairment, and Vulnerability to Dementia

(2014) Mak Adam Daulatzai   NEUROCHEMICAL RESEARCH

Bifidobacteriaexert strain-specific effects on stress-related behavior and physiology in BALB/c mice

(2014) H. M. Savignac et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Correlation between the human fecal microbiota and depression

(2014) A. Naseribafrouei et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Short-Term Effect of Antibiotics on Human Gut Microbiota

(2014) Suchita Panda et al.   PLoS One

Enteric Bacterial Metabolites Propionic and Butyric Acid Modulate Gene Expression, Including CREB-Dependent Catecholaminergic Neurotransmission, in PC12 Cells - Possible Relevance to Autism Spectrum Disorders

(2014) Bistra B. Nankova et al.   PLoS One

Modulation of Intestinal Microbiota by the Probiotic VSL#3 Resets Brain Gene Expression and Ameliorates the Age-Related Deficit in LTP

(2014) Eleonora Distrutti et al.   PLoS One

Absence of the gut microbiota enhances anxiety-like behavior and neuroendocrine response to acute stress in rats

(2014) Michèle Crumeyrolle-Arias et al.   PSYCHONEUROENDOCRINOLOGY

Prebiotic intake reduces the waking cortisol response and alters emotional bias in healthy volunteers

(2014) Kristin Schmidt et al.   PSYCHOPHARMACOLOGY

An intestinal commensal symbiosis factor controls neuroinflammation via TLR2-mediated CD39 signalling

(2014) Yan Wang et al.   Nature Communications

GPR41/FFAR3 and GPR43/FFAR2 as Cosensors for Short-Chain Fatty Acids in Enteroendocrine Cells vs FFAR3 in Enteric Neurons and FFAR2 in Enteric Leukocytes

(2013) Mark K. Nøhr et al.   ENDOCRINOLOGY

Physical comorbidity and its relevance on mortality in schizophrenia: a naturalistic 12-year follow-up in general hospital admissions

(2013) Dieter Schoepf et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Comparative analysis of anti-toxoplasmic activity of antipsychotic drugs and valproate

(2013) Guillaume Fond et al.   EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE

Lactobacillus johnsonii inhibits indoleamine 2,3-dioxygenase and alters tryptophan metabolite levels in BioBreeding rats

(2013) Ricardo Valladares et al.   FASEB JOURNAL

Consumption of Fermented Milk Product With Probiotic Modulates Brain Activity

(2013) Kirsten Tillisch et al.   GASTROENTEROLOGY

Microbial genes, brain & behaviour - epigenetic regulation of the gut-brain axis

(2013) R. M. Stilling et al.   GENES BRAIN AND BEHAVIOR

Probiotics, gut microbiota and health

(2013) M.-J. Butel   MEDECINE ET MALADIES INFECTIEUSES

Commensal microbiota modulate murine behaviors in a strictly contamination-free environment confirmed by culture-based methods

(2013) R. Nishino et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Altered colonic function and microbiota profile in a mouse model of chronic depression

(2013) A. J. Park et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Melancholic microbes: a link between gut microbiota and depression?

(2013) T. G. Dinan et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Probiotic gut effect prevents the chronic psychological stress-induced brain activity abnormality in mice

(2013) A. Ait-Belgnaoui et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Serotonin and beyond: therapeutics for major depression

(2013) P. Blier et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Microbial Symbionts Accelerate Wound Healing via the Neuropeptide Hormone Oxytocin

(2013) Theofilos Poutahidis et al.   PLoS One

Psychiatric Disorders in Toxoplasma Seropositive Patients--The CD8 Connection

(2013) R. Bhadra et al.   SCHIZOPHRENIA BULLETIN

Fiber and Prebiotics: Mechanisms and Health Benefits

(2013) Joanne Slavin   Nutrients

Antipsychotics and the gut microbiome: olanzapine-induced metabolic dysfunction is attenuated by antibiotic administration in the rat

(2013) K J Davey et al.   Translational Psychiatry

Critical role of gut microbiota in the production of biologically active, free catecholamines in the gut lumen of mice

(2012) Yasunari Asano et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

A Population-Based Study of Shared Genetic Variation Between Premorbid IQ and Psychosis Among Male Twin Pairs and Sibling Pairs From Sweden

(2012) Stanley Zammit   ARCHIVES OF GENERAL PSYCHIATRY

Elevated Fecal Short Chain Fatty Acid and Ammonia Concentrations in Children with Autism Spectrum Disorder

(2012) Lv Wang et al.   DIGESTIVE DISEASES AND SCIENCES

Increased IgA and IgM responses against gut commensals in chronic depression: Further evidence for increased bacterial translocation or leaky gut

(2012) Michael Maes et al.   JOURNAL OF AFFECTIVE DISORDERS

γ-Aminobutyric acid production by culturable bacteria from the human intestine

(2012) E. Barrett et al.   JOURNAL OF APPLIED MICROBIOLOGY

Stimulation of Cadaverine Production by Foodborne Pathogens in the Presence ofLactobacillus,Lactococcus, andStreptococcusspp.

(2012) Esmeray Kuley et al.   JOURNAL OF FOOD SCIENCE

The enteric bacterial metabolite propionic acid alters brain and plasma phospholipid molecular species: further development of a rodent model of autism spectrum disorders

(2012) Raymond H Thomas et al.   Journal of Neuroinflammation

The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner

(2012) G Clarke et al.   MOLECULAR PSYCHIATRY

Gastrointestinal Conditions in Children With Autism Spectrum Disorder: Developing a Research Agenda

(2012) Daniel L. Coury et al.   PEDIATRICS

Histamine Derived from Probiotic Lactobacillus reuteri Suppresses TNF via Modulation of PKA and ERK Signaling

(2012) Carissa M. Thomas et al.   PLoS One

Increased Oral Detection, but Decreased Intestinal Signaling for Fats in Mice Lacking Gut Microbiota

(2012) Frank A. Duca et al.   PLoS One

Effect of Maternal Probiotic Intervention on HPA Axis, Immunity and Gut Microbiota in a Rat Model of Irritable Bowel Syndrome

(2012) Javad Barouei et al.   PLoS One

Prevention of gut leakiness by a probiotic treatment leads to attenuated HPA response to an acute psychological stress in rats

(2012) Afifa Ait-Belgnaoui et al.   PSYCHONEUROENDOCRINOLOGY

Gender-dependent consequences of chronic olanzapine in the rat: effects on body weight, inflammatory, metabolic and microbiota parameters

(2012) Kieran J. Davey et al.   PSYCHOPHARMACOLOGY

After GWAS: Searching for Genetic Risk for Schizophrenia and Bipolar Disorder

(2011) Elliot S. Gershon et al.   AMERICAN JOURNAL OF PSYCHIATRY

Up-regulation of intestinal type 1 taste receptor 3 and sodium glucose luminal transporter-1 expression and increased sucrose intake in mice lacking gut microbiota

(2011) T. D. Swartz et al.   BRITISH JOURNAL OF NUTRITION

The Intestinal Microbiota Affect Central Levels of Brain-Derived Neurotropic Factor and Behavior in Mice

(2011) Premysl Bercik et al.   GASTROENTEROLOGY

The anxiolytic effect of Bifidobacterium longum NCC3001 involves vagal pathways for gut-brain communication

(2011) P. Bercik et al.   NEUROGASTROENTEROLOGY AND MOTILITY

The level of arabinitol in autistic children after probiotic therapy

(2011) Joanna Kałużna-Czaplińska et al.   NUTRITION

Ingestion of Lactobacillus strain regulates emotional behavior and central GABA receptor expression in a mouse via the vagus nerve

(2011) J. A. Bravo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Enteroendocrine cells: a site of ‘taste’ in gastrointestinal chemosensing

(2011) Catia Sternini et al.   Current Opinion in Endocrinology Diabetes and Obesity

Assessment of psychotropic-like properties of a probiotic formulation ( Lactobacillus helveticus R0052 and Bifidobacterium longum R0175) in rats and human subjects

(2010) Michaël Messaoudi et al.   BRITISH JOURNAL OF NUTRITION

Mode of delivery affects the bacterial community in the newborn gut

(2010) Giacomo Biasucci et al.   EARLY HUMAN DEVELOPMENT

Chronic Gastrointestinal Inflammation Induces Anxiety-Like Behavior and Alters Central Nervous System Biochemistry in Mice

(2010) Premysl Bercik et al.   GASTROENTEROLOGY

Reshaping the gut microbiome with bacterial transplantation and antibiotic intake

(2010) C. Manichanh et al.   GENOME RESEARCH

A polysaccharide from the human commensal Bacteroides fragilis protects against CNS demyelinating disease

(2010) J Ochoa-Repáraz et al.   Mucosal Immunology

A human gut microbial gene catalogue established by metagenomic sequencing

(2010) Junjie Qin et al.   NATURE

Reduced anxiety-like behavior and central neurochemical change in germ-free mice

(2010) K. M. Neufeld et al.   NEUROGASTROENTEROLOGY AND MOTILITY

Increased urinary excretion of a 3-(3-hydroxyphenyl)-3-hydroxypropionic acid (HPHPA), an abnormal phenylalanine metabolite ofClostridiaspp. in the gastrointestinal tract, in urine samples from patients with autism and schizophrenia

(2010) William Shaw   NUTRITIONAL NEUROSCIENCE

A Novel Probiotic Mixture Exerts a Therapeutic Effect on Experimental Autoimmune Encephalomyelitis Mediated by IL-10 Producing Regulatory T Cells

(2010) Shahram Lavasani et al.   PLoS One

Inflammation-associated depression: From serotonin to kynurenine

(2010) Robert Dantzer et al.   PSYCHONEUROENDOCRINOLOGY

Maternal separation as a model of brain–gut axis dysfunction

(2010) Siobhain M. O’Mahony et al.   PSYCHOPHARMACOLOGY

Gastrointestinal microbiology enters the metagenomics era

(2009) Daniel N Frank et al.   CURRENT OPINION IN GASTROENTEROLOGY

Changes in gut microbiota control inflammation in obese mice through a mechanism involving GLP-2-driven improvement of gut permeability

(2009) P. D. Cani et al.   GUT

Effects of the histone deacetylase inhibitor sodium butyrate in models of depression and anxiety

(2009) Brigitta B. Gundersen et al.   NEUROPHARMACOLOGY

Sex-specific differences in side effects of psychotropic drugs: genes or gender?

(2009) Sara Haack et al.   PHARMACOGENOMICS

Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites

(2009) W. R. Wikoff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A randomized, double-blind, placebo-controlled pilot study of a probiotic in emotional symptoms of chronic fatigue syndrome

(2009) A Venket Rao et al.   Gut Pathogens

Intracerebroventricular injections of the enteric bacterial metabolic product propionic acid impair cognition and sensorimotor ability in the Long–Evans rat: Further development of a rodent model of autism

(2008) Sandy R. Shultz et al.   BEHAVIOURAL BRAIN RESEARCH

Characterization of Glutamate Decarboxylase from a High γ-Aminobutyric Acid (GABA)-Producer,Lactobacillus paracasei

(2008) Noriko KOMATSUZAKI et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Glutamate Decarboxylase fromLactobacillus brevis: Activation by Ammonium Sulfate

(2008) Kazumi HIRAGA et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Autism-like behavioral phenotypes in BTBR T+tf/J mice

(2007) H. G. McFarlane et al.   GENES BRAIN AND BEHAVIOR