Article
Medicine, General & Internal
Jennifer Jardine, Kate Walker, Ipek Gurol-Urganci, Kirstin Webster, Patrick Muller, Jane Hawdon, Asma Khalil, Tina Harris, Jan van der Meulen
Summary: The study reveals that socioeconomic and ethnic inequalities contribute to adverse pregnancy outcomes in England, with the most significant disparities observed among Black and South Asian women in the most socioeconomically deprived groups.
Review
Immunology
Emily F. Cornish, Thomas McDonnell, David J. Williams
Summary: Chronic inflammatory placental disorders, including villitis of unknown etiology, chronic histiocytic intervillositis, and massive perivillous fibrin deposition, are rare but devastating gestational syndromes associated with adverse pregnancy outcome. These disorders are characterized by infiltration of maternal immune cells in the placenta, disrupting the gas exchange between the mother and fetus, and have a significant risk of recurrence in subsequent pregnancies.
FRONTIERS IN IMMUNOLOGY
(2022)
Review
Medicine, General & Internal
Kjerstine Breintoft, Regitze Pinnerup, Tine Brink Henriksen, Dorte Rytter, Niels Uldbjerg, Axel Forman, Linn Hakonsen Arendt
Summary: Women with endometriosis are at increased risk of gestational hypertension, pre-eclampsia, preterm birth, placenta previa, placental abruption, cesarean section, and stillbirth during pregnancy. Some studies suggest a potential association between endometriosis and spontaneous hemoperitoneum and bowel perforation in pregnancy.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Acoustics
I. Papastefanou, E. Gyokova, B. Gungil, A. Syngelaki, K. H. Nicolaides
Summary: This study aims to investigate the association between birth weight and gestational age at delivery with adverse neonatal outcomes and describe the distribution of adverse neonatal outcomes within different risk strata derived from a population stratification scheme based on the midgestation risk assessment for small-for-gestational-age neonates. The results showed that birth weight has a continuous association with adverse neonatal outcomes, influenced by gestational age. Pregnancies at high risk of small-for-gestational-age, estimated at midgestation, are also at increased risk for adverse neonatal outcomes.
ULTRASOUND IN OBSTETRICS & GYNECOLOGY
(2023)
Article
Obstetrics & Gynecology
Samantha C. Lean, Rebecca L. Jones, Stephen A. Roberts, Alexander E. P. Heazell
Summary: This study revealed that smoking is associated with adverse pregnancy outcome in older women, while multiparity can decrease the likelihood of adverse outcomes. In older mothers with adverse outcomes, oxidative stress markers were increased, and levels of maternal circulating placental hormones were reduced.
BMC PREGNANCY AND CHILDBIRTH
(2021)
Article
Obstetrics & Gynecology
Sukainah Al Khalaf, Karolina Kublickiene, Marius Kublickas, Ali S. Khashan, Alexander E. P. Heazell
Summary: The study found that women with a history of stillbirth in the first two pregnancies have an increased risk of stillbirth or other adverse outcomes in the third pregnancy. Additional surveillance is recommended for these women.
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
(2023)
Article
Medicine, General & Internal
Bartosz Czuba, Piotr Tousty, Wojciech Cnota, Dariusz Borowski, Agnieszka Jagielska, Mariusz Dubiel, Anna Fuchs, Magda Fraszczyk-Tousty, Sylwia Dzidek, Anna Kajdy, Grzegorz Swiercz, Sebastian Kwiatkowski
Summary: This study examined the differences in first-trimester fetal hepatic artery flows depending on pregnancy outcomes. It found that assessing hepatic artery flow could be a valuable tool in predicting adverse pregnancy outcomes, especially karyotype abnormalities and congenital heart defects.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Obstetrics & Gynecology
Ulla Sovio, Francesca Gaccioli, Emma Cook, D. Stephen Charnock-Jones, Gordon C. S. Smith
Summary: This study aimed to determine the inter-relationships between five first-trimester biomarkers and a range of adverse pregnancy outcomes. The results showed that these biomarkers were associated with fetal growth restriction, preterm birth, and preeclampsia, indicating heterogeneity in the underlying pathophysiological pathways for different types of adverse pregnancy outcomes.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2023)
Article
Obstetrics & Gynecology
Prakash Prabhakarrao Doke, Sonali Hemant Palkar, Jayashree Sachin Gothankar, Archana Vasantrao Patil, Amruta Paresh Chutke, Prasad Dnyandeo Pore, Aniruddha Vinayakrao Deshpande, Khanindra Kumar Bhuyan, Madhusudan Vamanrao Karnataki, Aparna Nishikant Shrotri
Summary: This study aimed to estimate the prevalence of various pregnancy outcomes and their association with certain risk factors during the preconception phase, based on a baseline survey in Nashik District, India. The findings showed that factors such as parental consanguinity, pre-existing maternal illness, heavy work during pregnancy, tobacco consumption, and alcohol consumption were associated with adverse pregnancy outcomes like abortion, stillbirth, preterm birth, and low birth weight. Implementing interventions targeting maternal behavior and addressing these risk factors is crucial to achieving better pregnancy outcomes.
BMC PREGNANCY AND CHILDBIRTH
(2021)
Article
Obstetrics & Gynecology
S. L. Son, A. A. Allshouse, J. M. Page, M. P. Debbink, H. Pinar, U. Reddy, K. J. Gibbins, B. J. Stoll, C. B. Parker, D. J. Dudley, M. W. Varner, R. M. Silver
Summary: The study found that 23.4% of stillbirths had one or more major anomalies, compared to 4.3% of live births. The presence of anomalies increased the odds of stillbirth, with a higher association observed with an increasing number of anomalies. Regardless of the affected organ system, the presence of an anomaly was found to increase the odds of stillbirth.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2021)
Review
Obstetrics & Gynecology
Danya Bakhbakhi, Dimitrios Siassakos, Anna Davies, Abi Merriel, Katie Barnard, Emma Stead, Clare Shakespeare, James M. N. Duffy, Lisa Hinton, Karolina McDowell, Anna Lyons, Abigail Fraser, Christy Burden, iCHOOSE Collaborat Grp
Summary: The research on interventions after stillbirth diagnosis lacks consistent outcome reporting and evidence improvement. The establishment of a core outcome set is necessary for standardizing outcome collection and reporting in stillbirth care research.
BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
(2023)
Article
Obstetrics & Gynecology
Nicole Graham, Louise Stephens, Edward D. Johnstone, Alexander E. P. Heazell
Summary: Placental examination at the time of stillbirth is crucial for predicting the risk of adverse outcomes in subsequent pregnancies, while information about maternal characteristics and classification of the cause of stillbirth does not provide significant prognostic information.
ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA
(2021)
Review
Public, Environmental & Occupational Health
Antoine David, Klara M. Posfay-Barbe, Carina Aguiar Nogueira, Laurence Toutous Trellu
Summary: Syphilis remains a global public health problem, particularly among women of childbearing age. The increase in congenital syphilis cases has led to devastating consequences. Although measures have contributed to a decline in global incidence, many countries are still facing an escalating crisis.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Medicine, General & Internal
Emma Rasmark Roepke, Ole Bjarne Christiansen, Karin Kallen, Stefan R. Hansson
Summary: Recurrent pregnancy loss (RPL) is associated with placental dysfunctional disorders, with women with RPL having a higher risk during pregnancy and requiring improved antenatal surveillance.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Physiology
Mengchen Li, Charles E. Wood, Maureen Keller-Wood
Summary: Maternal stress during pregnancy can lead to adverse pregnancy outcomes, including stillbirth and prematurity. This study found that chronic elevation in maternal cortisol levels affects fetal cardiac adaptation during the transition from in utero to ex utero life. These findings suggest that excessive in utero corticosteroid exposure negatively affects fetal cardiac adaptation and that chronic maternal stress or hypersecretion of corticosteroids may contribute to adverse obstetric outcomes.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
(2022)