期刊
CLINICS IN GERIATRIC MEDICINE
卷 32, 期 1, 页码 175-+出版社
W B SAUNDERS CO-ELSEVIER INC
DOI: 10.1016/j.cger.2015.08.006
关键词
Chronic lymphocytic leukemia; Non-Hodgkin lymphoma; Elderly
Chronic lymphocytic leukemia affects less than 1% of US adults but is the most common leukemia, and it primarily affects older patients. Non-Hodgkin lymphomas are the seventh most common cancers in the United States and also primarily affect older patients. In general, older patients should be treated differently than their younger, fitter counterparts. Fitness level and comorbidities should be taken into account when planning treatment. First-line treatment of most of these B-cell lymphoproliferative disorders consists of chemoimmunotherapy. In relapsed and refractory disease, there is a growing role for therapies targeting the B-cell receptor signaling pathway.
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