Targeted inhibition of endothelial calpain delays wound healing by reducing inflammation and angiogenesis

Selective deletion of endothelial cell calpain in mice reduces diabetic cardiomyopathy by improving angiogenesis

(2019) Xiaomei Teng et al.   DIABETOLOGIA

Dysregulation of Calpain Proteolytic Systems Underlies Degenerative Vascular Disorders

(2018) Takuro Miyazaki et al.   Journal of Atherosclerosis and Thrombosis

Injury-activated glial cells promote wound healing of the adult skin in mice

(2018) Vadims Parfejevs et al.   Nature Communications

Immune Regulation of Skin Wound Healing: Mechanisms and Novel Therapeutic Targets

(2018) Jacqueline Larouche et al.   Advances in Wound Care

Genetic disruption of calpain-1 and calpain-2 attenuates tumorigenesis in mouse models of HER2+ breast cancer and sensitizes cancer cells to doxorubicin and lapatinib

(2018) James A. MacLeod et al.   Oncotarget

The Abnormal Architecture of Healed Diabetic Ulcers Is the Result of FAK Degradation by Calpain 1

(2017) Wei Liu et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Thromboxane Governs the Differentiation of Adipose-Derived Stromal Cells Toward Endothelial Cells In Vitro and In VivoNovelty and Significance

(2016) Yujun Shen et al.   CIRCULATION RESEARCH

Calpain Genetic Disruption and HSP90 Inhibition Combine To Attenuate Mammary Tumorigenesis

(2016) Stacy Grieve et al.   MOLECULAR AND CELLULAR BIOLOGY

Loss-of-Function Mutations in CAST Cause Peeling Skin, Leukonychia, Acral Punctate Keratoses, Cheilitis, and Knuckle Pads

(2015) Zhimiao Lin et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Activation of α7nAChR Promotes Diabetic Wound Healing by Suppressing AGE-Induced TNF-α Production

(2015) Miao-Wu Dong et al.   INFLAMMATION

The oncoprotein HBXIP enhances migration of breast cancer cells through increasing filopodia formation involving MEKK2/ERK1/2/Capn4 signaling

(2014) Yinghui Li et al.   CANCER LETTERS

Inhibition of calpain reduces oxidative stress and attenuates endothelial dysfunction in diabetes

(2014) Bainian Chen et al.   Cardiovascular Diabetology

Capn4 contributes to tumour growth and metastasis of hepatocellular carcinoma by activation of the FAK-Src signalling pathways

(2014) Zhi Dai et al.   JOURNAL OF PATHOLOGY

A statistical analysis of murine incisional and excisional acute wound models

(2014) David M. Ansell et al.   WOUND REPAIR AND REGENERATION

Apoptosis and angiogenesis: an evolving mechanism for fibrosis

(2013) Ariel Johnson et al.   FASEB JOURNAL

Myeloid cell RelA/p65 promotes lung cancer proliferation through Wnt/β-catenin signaling in murine and human tumor cells

(2013) D Li et al.   ONCOGENE

Involvement of calmodulin and calmodulin kinase II in tumor necrosis factor alpha-induced survival of bone marrow derived macrophages

(2012) Jean-Yves Tano et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The role of Ca2+/calmodulin-dependent protein kinase II and calcineurin in TNF-α-induced myocardial hypertrophy

(2012) Gui-Jun Wang et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Calpain Activity Is Essential in Skin Wound Healing and Contributes to Scar Formation

(2012) Dany Nassar et al.   PLoS One

Calpain Activation Promotes BACE1 Expression, Amyloid Precursor Protein Processing, and Amyloid Plaque Formation in a Transgenic Mouse Model of Alzheimer Disease

(2010) Bin Liang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Wound repair and regeneration

(2008) Geoffrey C. Gurtner et al.   NATURE