Article
Immunology
Ene Gbenewei, Terna Nomhwange, Lydia Taiwo, Isiaka Ayodeji, Kabir Yusuf, Anne E. Jean Baptiste, Peter Nsubuga, Fiona Braka, Joseph Oteri, Faisal Shuaib
Summary: This article discusses Nigeria's experience with AEFI reporting during the 2017/2018 Measles vaccination campaign, identifying 6,214 suspected cases with a majority being non-serious and resolving fully with no long-term sequalae. Adequate reporting, investigation, and management are essential in managing the risk of disruptions in mass vaccination campaigns.Deployment of supervisors during campaigns and real-time follow-up by national operations teams play crucial roles in improving the identification and reporting of suspected AEFIs and in decision-making and intervention.
Article
Public, Environmental & Occupational Health
Hossein Azarpanah, Mohsen Farhadloo, Rustam Vahidov, Louise Pilote
Summary: This study focuses on addressing concerns regarding vaccine Adverse Events (AEs) to increase vaccine acceptance, as well as identifying potential cognitive biases connecting vaccine hesitancy concerns to vaccine-hesitant behaviors in the vaccine decision-making process. Results show that the majority of reported AEs are not serious, and 15 potential cognitive biases affecting vaccination decision-making and contributing to vaccine hesitancy were identified. Efforts to increase vaccination uptake should take into account and minimize the impact of these cognitive biases.
Article
Immunology
Van Nhi Tran, Hoang An Nguyen, Thi Thanh An Le, Thanh Tung Truong, Phuong Thao Nguyen, Thi Thu Hoai Nguyen
Summary: This study in Vietnamese individuals vaccinated with the AZD1222 vaccine found that females were more prone to AEFI, particularly gastrointestinal symptoms, than males. Age and number of vaccine doses were also important factors affecting AEFI.
Article
Medicine, General & Internal
Minji Jeon, Jehun Kim, Chi Eun Oh, Jin-Young Lee
Summary: The study focused on investigating adverse events following immunization (AEFIs) for COVID-19 among healthcare workers (HCWs) who received the ChAdOx1 nCoV-19 vaccine. The majority of AEFIs reported were mild-to-moderate in severity, with older age groups experiencing fewer and less severe AEFIs. No serious events requiring hospitalization were reported, and most AEFIs resolved within a few days. The use of the Mobile Vaccine Adverse Events Reporting System (MVAERS) was found to be helpful in monitoring and sharing accurate information about vaccination against COVID-19.
JOURNAL OF KOREAN MEDICAL SCIENCE
(2021)
Article
Biotechnology & Applied Microbiology
Yu Hu, Xuejiao Pan, Linzhi Shen, Fuxing Chen, Ying Wang, Hui Liang, Yaping Chen, Huakun Lv
Summary: The study evaluated the reporting rate of adverse events following immunization with the quadrivalent human papillomavirus vaccine in Zhejiang province, and compared it with other vaccines. The most common event reported was fever/redness/induration, and no new or unexpected safety concerns were identified in the analysis.
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2021)
Article
Immunology
Yunhua Wei, Yan Wang, Jian Liu, Yan Zha, Yuqi Yang, Ni Li, Yalin Zhou, Jinli Zhu, Neil Roberts, Lin Liu, Yaying Li
Summary: A comparative analysis was conducted to investigate the potential risk factors of Adverse Events Following Immunization (AEFI) after receiving different booster vaccines. The study found that doctors and women had a higher risk of adverse reactions, but overall, the rates of AEFI in all three booster groups were acceptable.
Article
Biotechnology & Applied Microbiology
Xuejiao Pan, Huakun Lv, Fuxing Chen, Ying Wang, Hui Liang, Linzhi Shen, Yaping Chen, Yu Hu
Summary: This study summarized passive surveillance data for adverse events following immunization in Zhejiang province, showing that AEFI mainly occurred among infants under 1 year old, with majority of reported cases not serious. The findings suggest the continuous use of national AEFI surveillance system as a monitoring tool.
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2021)
Review
Pediatrics
Manoja Kumar Das
Summary: Although vaccines undergo rigorous testing, concerns about their safety persist globally. Safety concerns related to measles, pentavalent, and HPV vaccines have significantly impacted vaccine coverage. Surveillance of adverse events following immunization (AEFI) faces challenges including reporting biases. Specialized studies are mandated to investigate adverse events of special interest (AESI) following vaccination. The exact pathophysiology of many AEFIs/AESIs remains unknown. Genetic factors, gender, age, and pro-inflammatory risk factors may contribute to AEFIs/AESIs. The uncertainty surrounding the frequency, profile, interval, and severity of AEFIs/AESIs, as well as variations across populations and the absence of definite markers, may create a black box effect for vaccines. Addressing these unanswered questions and effectively communicating with stakeholders is crucial to combat the anti-vaccine movement.
INDIAN JOURNAL OF PEDIATRICS
(2023)
Article
Immunology
Miguel Garcia-Grimshaw, Santa Elizabeth Ceballos-Liceaga, Anaclara Michel-Chavez, Mario Garcia-Alanis, Arturo Cadena-Fernandez, Javier Andres Galnares-Olalde, Guillermo Carbajal-Sandoval, Daniel Amado Carrillo-Garcia, Noe Hernandez-Valdivia, Laura E. Hernandez-Vanegas, Maria del Mar Saniger-Alba, Alonso Gutierrez-Romero, Jose Luis Diaz-Ortega, Gustavo Reyes-Teran, Hugo Lopez-Gatell, Fernando Daniel Flores-Silva, Carlos Cantu-Brito, Erwin Chiquete, Antonio Arauz, Sergio Ivan Valdes-Ferrer
Summary: mRNA-based COVID-19 vaccines are effective, but persistent vaccine hesitancy is partly due to a misperception of their potential adverse events. This study described the anatomy and associated factors of developing NSSS among BNT162b2 recipients, suggesting that the benign nature of these symptoms may help dissipate hesitation towards this vaccine.
Article
Immunology
Pietro Ferrara, Domenico Ponticelli, Lorenzo Losa, Claudia Romeo, Roberto Magliuolo, Andrea Vitale, Anna Zampella, Lucia Alleanza, Mario Borrelli, Beniamino Schiavone, Lorenzo Giovanni Mantovani
Summary: A study conducted on healthcare workers in an Italian teaching hospital found that the reporting of adverse events following immunization (AEFI) was lower after the administration of a booster dose of COVID-19 vaccine compared to the primary vaccination series. The study also revealed that individuals who experienced the same post-vaccination symptoms after the second dose were more likely to report AEFI after the third dose. These findings provide important data for informing booster vaccination strategies in healthcare workers and the adult population.
Article
Immunology
Francisco Tsz Tsun Lai, Gilbert T. Chua, Edward Wai Wa Chan, Lei Huang, Mike Yat Wah Kwan, Tiantian Ma, Xiwen Qin, Celine Sze Ling Chui, Xue Li, Eric Yuk Fai Wan, Carlos King Ho Wong, Esther Wai Yin Chan, Ian Chi Kei Wong, Patrick Ip
Summary: A retrospective cohort study found that the risk of adverse events following BNT162b2 vaccination in adolescents aged 12-18 is not significantly increased, except for myocarditis and sleeping disturbances after the second dose.
EMERGING MICROBES & INFECTIONS
(2022)
Article
Immunology
Giorgia Solda, Edoardo Barvas, Jacopo Lenzi, Zeno Di Valerio, Giusy La Fauci, Susanna Guttmann, Rossano Riccardi, Maria Pia Fantini, Aurelia Salussolia, Marco Montalti, Davide Gori
Summary: This study evaluated the occurrence of short-term adverse events following immunization (AEFIs) in Parkinson's Disease (PD) and Multiple Sclerosis (MS) patients who received Gam-COVID-Vac and Pfizer-BioNTech vaccines. The results showed that most reported symptoms were mild, and the frequency of AEFIs in PD patients was significantly lower than in the control group.
Article
Immunology
Sz-An Tsai, Chun-Yi Lu, Tzu- Chen, Shih-Pei Huang, Yong-Chen Chen
Summary: This study examined the incidence of serious adverse events after HPV vaccination among Taiwanese girls and found no significant increased risk associated with the vaccine.
Article
Primary Health Care
Vikrant S. Pagar, Sushant S. Chavan, Sarika P. Patil, Anant Borde, Amol D. Kinge, Naveen Khargekar
Summary: The study revealed that adverse events following immunization (AEFI) mainly occurred in infants between 0 and 3 months of age, with males being more susceptible. The most common AEFI were convulsions and fever, with the majority occurring within 12 hours of immunization.
JOURNAL OF FAMILY MEDICINE AND PRIMARY CARE
(2021)
Article
Biochemistry & Molecular Biology
Marie O. Pohl, Idoia Busnadiego, Verena Kufner, Irina Glas, Umut Karakus, Stefan Schmutz, Maryam Zaheri, Irene Abela, Alexandra Trkola, Michael Huber, Silke Stertz, Benjamin G. Hale
Summary: This study characterized different SARS-CoV-2 isolates from major European clades during the early phase of the pandemic in 2020 and identified sequence features associated with distinct phenotypes, such as variations affecting replication in specific cell types. It highlights the importance of carefully monitoring newly emerging variants or potential variants of concern in SARS-CoV-2 stocks.
Review
Immunology
Carleigh B. Krubiner, Ruth R. Faden, Ruth A. Karron, Margaret O. Little, Anne D. Lyerly, Jon S. Abramson, Richard H. Beigi, Alejandro R. Cravioto, Anna P. Durbin, Bruce G. Gellin, Swati B. Gupta, David C. Kaslow, Sonali Kochhar, Florencia Luna, Carla Saenz, Jeanne S. Sheffield, Paulina O. Tindana
Summary: Zika virus, influenza, and Ebola outbreaks have shed light on the unique impacts on pregnant women and their offspring, highlighting the need for proactive consideration in vaccine research and response efforts. The exclusion of pregnant women in research agendas and vaccine campaigns is unjust and problematic from a public health perspective. To address these issues, new approaches to public health preparedness and vaccine research are necessary.
Article
Infectious Diseases
Christopher E. Troeger, Ibrahim A. Khalil, Brigette F. Blacker, Molly H. Biehl, Samuel B. Albertson, Stephanie R. M. Zimsen, Puja C. Rao, Degu Abate, Amha Admasie, Alireza Ahmadi, Mohamed Lemine Cheikh Brahim Ahmed, Chalachew Genet Akal, Fares Alahdab, Noore Alam, Kefyalew Addis Alene, Vahid Alipour, Syed Mohamed Aljunid, Rajaa M. Al-Raddadi, Nelson Alvis-Guzman, Saeed Amini, Mina Anjomshoa, Carl Abelardo T. Antonio, Jalal Arabloo, Olatunde Aremu, Hagos Tasew Atalay, Suleman Atique, Euripide F. G. A. Avokpaho, Samah Awad, Ashish Awasthi, Alaa Badawi, Kalpana Balakrishnan, Joseph Adel Mattar Banoub, Aleksandra Barac, Quique Bassat, Neeraj Bedi, Derrick A. Bennett, Krittika Bhattacharyya, Zulfiqar A. Bhutta, Ali Bijani, Corey B. Bills, Josip Car, Felix Carvalho, Carlos A. Castaneda-Orjuela, Kate Causey, Devasahayam J. Christopher, Aaron J. Cohen, Lalit Dandona, Rakhi Dandona, Ahmad Daryani, Feleke Mekonnen Demeke, Shirin Djalalinia, Manisha Dubey, Eleonora Dubljanin, Eyasu Ejeta Duken, Maysaa El Sayed Zaki, Aman Yesuf Endries, Eduarda Fernandes, Florian Fischer, Joseph Frostad, Nancy Fullman, William M. Gardner, Birhanu Geta, Keyghobad Ghadiri, Giuseppe Gorini, Alessandra C. Goulart, Yuming Guo, Gessessew Bugssa Hailu, Arvin Haj-Mirzaian, Arya Haj-Mirzaian, Samer Hamidi, Hamid Yimam Hassen, Chi Linh Hoang, Nobuyuki Horita, Mihaela Hostiuc, Zakir Hussain, Seyed Sina Naghibi Irvani, Spencer L. James, Ravi Prakash Jha, Jost B. Jonas, Andre Karch, Amir Kasaeian, Tesfaye Dessale Kassa, Nicholas J. Kassebaum, Adane Teshome Kefale, Yousef Saleh Khader, Ejaz Ahmad Khan, Gulfaraz Khan, Md Nuruzzaman Khan, Young-Ho Khang, Abdullah T. Khoja, Ruth W. Kimokoti, Adnan Kisa, Sezer Kisa, Niranjan Kissoon, Luke D. Knibbs, Sonali Kochhar, Soewarta Kosen, Parvaiz A. Koul, Ai Koyanagi, Barthelemy Kuate Defo, G. Anil Kumar, Dharmesh Kumar Lal, Cheru Tesema Leshargie, Sonia Lewycka, Shanshan Li, Rakesh Lodha, Erlyn Rachelle King Macarayan, Marek Majdan, Abdullah A. Mamun, Helena Manguerra, Varshil Mehta, Addisu Melese, Ziad A. Memish, Desalegn Tadese Mengistu, Tuomo J. Meretoja, Tomislav Mestrovic, Bartosz Miazgowski, Erkin M. Mirrakhimov, Babak Moazen, Karzan Abdulmuhsin Mohammad, Shafiu Mohammed, Lorenzo Monasta, Catrin E. Moore, Lidia Morawska, Jonathan F. Mosser, Seyyed Meysam Mousavi, Srinivas Murthy, Ghulam Mustafa, Javad Nazari, Cuong Tat Nguyen, Huong Lan Thi Nguyen, Long Hoang Nguyen, Son Hoang Nguyen, Katie R. Nielsen, Muhammad Imran Nisar, Molly R. Nixon, Felix Akpojene Ogbo, Anselm Okoro, Andrew T. Olagunju, Tinuke O. Olagunju, Eyal Oren, Justin R. Ortiz, P. A. Mahesh, Smita Pakhale, Maarten J. Postma, Mostafa Qorbani, Reginald Quansah, Alireza Rafiei, Fakher Rahim, Vafa Rahimi-Movaghar, Rajesh Kumar Rai, Marissa Bettay Reitsma, Mohammad Sadegh Rezai, Aziz Rezapour, Maria Jesus Rios-Blancas, Luca Ronfani, Dietrich Rothenbacher, Salvatore Rubino, Zikria Saleem, Evanson Zondani Sambala, Abdallah M. Samy, Milena M. Santric Milicevic, Rodrigo Sarmiento-Suarez, Benn Sartorius, Miloje Savic, Monika Sawhney, Sonia Saxena, Alyssa Sbarra, Seyedmojtaba Seyedmousavi, Masood Ali Shaikh, Aziz Sheikh, Mika Shigematsu, David L. Smith, Chandrashekhar T. Sreeramareddy, Jeffrey D. Stanaway, Mu'awiyyah Babale Sufiyan, Mohamad-Hani Temsah, Belay Tessema, Bach Xuan Tran, Khanh Bao Tran, Afewerki Gebremeskel Tsadik, Irfan Ullah, Rachel L. Updike, Tommi Juhani Vasankari, Yousef Veisani, Fiseha Wadilo Wada, Yasir Waheed, Katie Welgan, Kirsten E. Wiens, Charles Shey Wiysonge, Ebrahim M. Yimer, Naohiro Yonemoto, Zoubida Zaidi, Heather J. Zar, Stephen S. Lim, Theo Vos, Ali H. Mokdad, Christopher J. L. Murray, Hmwe Hmwe Kyu, Simon I. Hay, Robert C. Reiner
LANCET INFECTIOUS DISEASES
(2020)
Article
Infectious Diseases
Christopher E. Troeger, Ibrahim A. Khalil, Brigette F. Blacker, Molly H. Biehl, Samuel B. Albertson, Stephanie R. M. Zimsen, Puja C. Rao, Degu Abate, Alireza Ahmadi, Mohamed Lemine Cheikh Brahim Ahmed, Chalachew Genet Akal, Fares Alahdab, Noore Alam, Kefyalew Addis Alene, Vahid Alipour, Syed Mohamed Aljunid, Rajaa M. Al-Raddadi, Nelson Alvis-Guzman, Saeed Amini, Nahla Hamed Anber, Mina Anjomshoa, Carl Abelardo T. Antonio, Jalal Arabloo, Olatunde Aremu, Hagos Tasew Atalay, Suleman Atique, Euripide F. G. A. Avokpaho, Samah Awad, Ashish Awasthi, Alaa Badawi, Kalpana Balakrishnan, Joseph Adel Mattar Banoub, Aleksandra Barac, Quique Bassat, Neeraj Bedi, Derrick A. Bennett, Krittika Bhattacharyya, Zulfiqar A. Bhutta, Ali Bijani, Josip Car, Felix Carvalho, Carlos A. Castaneda-Orjuela, Devasahayam J. Christopher, Lalit Dandona, Rakhi Dandona, Ahmad Daryani, Feleke Mekonnen Demeke, Aniruddha Deshpande, Shirin Djalalinia, Manisha Dubey, Eleonora Dubljanin, Eyasu Ejeta Duken, Maysaa El Sayed Zaki, Aman Yesuf Endries, Eduarda Fernandes, Florian Fischer, Nancy Fullman, William M. Gardner, Birhanu Geta, Keyghobad Ghadiri, Giuseppe Gorini, Alessandra C. Goulart, Yuming Guo, Gessessew Bugssa Hailu, Arvin Haj-Mirzaian, Arya Haj-Mirzaian, Samer Hamidi, Hamid Yimam Hassen, Chi Linh Hoang, Mihaela Hostiuc, Zakir Hussain, Seyed Sina Naghibi Irvani, Spencer L. James, Ravi Prakash Jha, Jost B. Jonas, Andre Karch, Amir Kasaeian, Tesfaye Dessale Kassa, Nicholas J. Kassebaum, Adane Teshome Kefale, Yousef Saleh Khader, Ejaz Ahmad Khan, Md Nuruzzaman Khan, Young-Ho Khang, Abdullah T. Khoja, Ruth W. Kimokoti, Adnan Kisa, Sezer Kisa, Niranjan Kissoon, Sonali Kochhar, Soewarta Kosen, Ai Koyanagi, Barthelemy Kuate Defo, G. Anil Kumar, Dharmesh Kumar Lal, Cheru Tesema Leshargie, Shanshan Li, Rakesh Lodha, Erlyn Rachelle King Macarayan, Marek Majdan, Abdullah A. Mamun, H. Manguerra, Addisu Melese, Ziad A. Memish, Desalegn Tadese Mengistu, Tuomo J. Meretoja, Tomislav Mestrovic, Bartosz Miazgowski, Erkin M. Mirrakhimov, Babak Moazen, Karzan Abdulmuhsin Mohammad, Shafiu Mohammed, Lorenzo Monasta, Catrin E. Moore, Jonathan F. Mosser, Seyyed Meysam Mousavi, Srinivas Murthy, Ghulam Mustafa, Javad Nazari, Cuong Tat Nguyen, Long Hoang Nguyen, Muhammad Imran Nisar, Molly R. Nixon, Felix Akpojene Ogbo, Anselm Okoro, Andrew T. Olagunju, Tinuke O. Olagunju, P. A. Mahesh, Smita Pakhale, Maarten J. Postma, Mostafa Qorbani, Reginald Quansah, Alireza Rafiei, Fakher Rahim, Vafa Rahimi-Movaghar, Rajesh Kumar Rai, Mohammad Sadegh Rezai, Aziz Rezapour, Maria Jesus Rios-Blancas, Luca Ronfani, Katherine Rosettie, Dietrich Rothenbacher, Saeed Safari, Zikria Saleem, Evanson Zondani Sambala, Abdallah M. Samy, Milena M. Santric Milicevic, Benn Sartorius, Monika Sawhney, Seyedmojtaba Seyedmousavi, Masood Ali Shaikh, Aziz Sheikh, Mika Shigematsu, David L. Smith, Joan B. Soriano, Chandrashekhar T. Sreeramareddy, Jeffrey D. Stanaway, Mu'awiyyah Babale Sufiyan, Teklay G. E. Teklu, Mohamad-Hani Temsah, Belay Tessema, Bach Xuan Tran, Khanh Bao Tran, Irfan Ullah, Rachel L. Updike, Tommi Juhani Vasankari, Yousef Veisani, Fiseha Wadilo Wada, Yasir Waheed, Marcia Weaver, Kirsten E. Wiens, Charles Shey Wiysonge, Ebrahim M. Yimer, Naohiro Yonemoto, Zoubida Zaidi, Heather J. Zar, Afshin Zarghi, Stephen S. Lim, Theo Vos, Ali H. Mokdad, Christopher J. L. Murray, Hmwe Hmwe Kyu, Simon I. Hay, Robert C. Reiner
LANCET INFECTIOUS DISEASES
(2020)
Article
Multidisciplinary Sciences
Joao C. Marques, Meng Li, Diane Schaak, Drew N. Robson, Jennifer M. Li
Editorial Material
Immunology
Kevin W. Graepel, Sonali Kochhar, Ellen W. Clayton, Kathryn E. Edwards
JOURNAL OF INFECTIOUS DISEASES
(2020)
Article
Virology
Kathryn M. Edwards, Sonali Kochhar
ANNUAL REVIEW OF VIROLOGY, VOL 7, 2020
(2020)
Review
Immunology
Marc Gurwith, Richard C. Condit, Jean-Louis Excler, James S. Robertson, Denny Kim, Patricia E. Fast, Stephen Drew, David Wood, Bettina Klug, Mike Whelan, Tamala Mallett Moore, Najwa Khuri-Bulos, Emily R. Smith, Robert T. Chen, Sonali Kochhar
Review
Immunology
Richard C. Condit, Denny Kim, James S. Robertson, Jean-Louis Excler, Marc Gurwith, Thomas P. Monath, George Pavlakis, Patricia E. Fast, Jonathan Smith, Emily R. Smith, Robert T. Chen, Sonali Kochhar
Editorial Material
Infectious Diseases
Naor Bar-Zeev, Sonali Kochhar
LANCET INFECTIOUS DISEASES
(2021)
Correction
Biochemistry & Molecular Biology
Jerome Amir Singh, Sonali Kochhar, Jonathan Wolff
Letter
Biochemistry & Molecular Biology
Jerome Amir Singh, Sonali Kochhar, Jonathan Wolff
Editorial Material
Immunology
Robert T. Chen, Sonali Kochhar, Richard Condit
Editorial Material
Immunology
Sonali Kochhar, Eve Dube, Janice Graham, Youngmee Jee, Ziad A. Memish, Lisa Menning, Hanna Nohynek, Daniel Salmon, Karina A. Top, Noni E. MacDonald
Editorial Material
Immunology
Sonali Kochhar, Uduak Okomo, Oluwatosin Nkereuwem, Anna Shaum, Jane F. Gidudu, Mustapha Bittaye, Sidat Fofana, Musa Marena, Markieu Janneh Kaira, Beate Kampmann, Ashley T. Longley