Mesenchymal Stromal Cell–Derived Small Extracellular Vesicles Induce Ischemic Neuroprotection by Modulating Leukocytes and Specifically Neutrophils

Polymorphonuclear Neutrophils Play a Decisive Role for Brain Injury and Neurological Recovery Poststroke

(2019) Dirk M. Hermann et al.   STROKE

Exosomes — beyond stem cells for restorative therapy in stroke and neurological injury

(2019) Zheng Gang Zhang et al.   Nature Reviews Neurology

Identification of the right cell sources for the production of therapeutically active extracellular vesicles in ischemic stroke

(2019) Bernd Giebel et al.   Annals of Translational Medicine

Extracellular Vesicles Derived from Hypoxic Human Mesenchymal Stem Cells Attenuate GSK3β Expression via miRNA-26a in an Ischemia-Reperfusion Injury Model

(2018) Hyewon Park et al.   YONSEI MEDICAL JOURNAL

Postacute Delivery of GABA A α5 Antagonist Promotes Postischemic Neurological Recovery and Peri-infarct Brain Remodeling

(2018) Ya-chao Wang et al.   STROKE

Mesenchymal Stem/Stromal Cell-Derived Extracellular Vesicles and Their Potential as Novel Immunomodulatory Therapeutic Agents

(2017) Verena Börger et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

MicroRNA-17–92 Cluster in Exosomes Enhance Neuroplasticity and Functional Recovery After Stroke in Rats

(2017) Hongqi Xin et al.   STROKE

Human mesenchymal and murine stromal cells support human lympho-myeloid progenitor expansion but not maintenance of multipotent haematopoietic stem and progenitor cells

(2016) Stefan Radtke et al.   CELL CYCLE

Role of Neutrophils in Exacerbation of Brain Injury After Focal Cerebral Ischemia in Hyperlipidemic Mice

(2015) Josephine Herz et al.   STROKE

Extracellular Vesicles Improve Post-Stroke Neuroregeneration and Prevent Postischemic Immunosuppression

(2015) Thorsten R. Doeppner et al.   Stem Cells Translational Medicine

Very-late-antigen-4 (VLA-4)-mediated brain invasion by neutrophils leads to interactions with microglia, increased ischemic injury and impaired behavior in experimental stroke

(2014) Jens Neumann et al.   ACTA NEUROPATHOLOGICA

MSC-derived exosomes: a novel tool to treat therapy-refractory graft-versus-host disease

(2014) L Kordelas et al.   LEUKEMIA

The mesenchymal stromal cells dilemma—does a negative phase III trial of random donor mesenchymal stromal cells in steroid-resistant graft-versus-host disease represent a death knell or a bump in the road?

(2013) Jacques Galipeau   CYTOTHERAPY

Systemic Administration of Exosomes Released from Mesenchymal Stromal Cells Promote Functional Recovery and Neurovascular Plasticity After Stroke in Rats

(2013) Hongqi Xin et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Human Mesenchymal Stem Cell Microvesicles for Treatment ofEscherichia coliEndotoxin-Induced Acute Lung Injury in Mice

(2013) Ying-gang Zhu et al.   STEM CELLS

Neutrophil depletion reduces edema formation and tissue loss following traumatic brain injury in mice

(2012) Ellinor Kenne et al.   Journal of Neuroinflammation

Characterisation of exosomes derived from human cells by nanoparticle tracking analysis and scanning electron microscopy

(2011) Viktoriya Sokolova et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Delayed post-ischaemic neuroprotection following systemic neural stem cell transplantation involves multiple mechanisms

(2009) Marco Bacigaluppi et al.   BRAIN