Article
Clinical Neurology
Ilona Merikanto, Katri Kantojarvi, Timo Partonen, Anu-Katriina Pesonen, Tiina Paunio
Summary: The study found weak associations between morningness-eveningness and health hazards, with the polygenic score for morningness explaining only a small proportion of the variation in diurnal preference or habitual sleep-wake schedule. Age had a greater influence on the sleep-wake schedule, suggesting that diurnal preference may be a more stable indicator than the sleep-wake schedule.
Article
Clinical Neurology
Katarzyna Nowakowska-Domaga, Malgorzata Juras-Darowny, Tadeusz Pietras, Patryk Stecz, Lukasz Mokros
Summary: This pilot study explores the role of rumination as a mediator between chronotype and sleep quality, chronotype and depressive symptoms. The results show that rumination is linked to poor sleep quality and increased depression. Morning affect and Distinctness correlated with rumination. Rumination was found to be a partial mediator of the associations between Morning Affect and sleep quality, Morning Affect and depression.
Article
Clinical Neurology
David R. Colelli, Gio R. Dela Cruz, Tetyana Kendzerska, Brian J. Murray, Mark I. Boulos
Summary: People's sleep patterns, known as chronotypes, are associated with their sleep quality and duration. Morning types tend to have better sleep quality and longer sleep duration, while evening types experience poorer sleep quality. Therefore, laboratory protocols should consider individuals' chronotypes when evaluating sleep.
JOURNAL OF SLEEP RESEARCH
(2023)
Article
Multidisciplinary Sciences
Lukas Liebig, Antje Bergmann, Karen Voigt, Erika Balogh, Bela Birkas, Nora Faubl, Theresa Kraft, Konrad Schoeniger, Henna Riemenschneider
Summary: Medical students are prone to harmful health behaviors due to academic stress. This study found that increased screen time among medical students is associated with delayed bedtime, shorter sleep duration, and poorer sleep quality. However, there was no significant association between screen time and sleep quality.
SCIENTIFIC REPORTS
(2023)
Review
Pharmacology & Pharmacy
Jacques Taillard, Patricia Sagaspe, Pierre Philip, Stephanie Bioulac
Summary: Sleep timing is influenced by the interplay between circadian and social time, with evening types being more vulnerable to social jetlag. Social jetlag and circadian disruption may lead to chronic sleep debt. Sleep and circadian disruption generally impact cognitive performance.
BIOCHEMICAL PHARMACOLOGY
(2021)
Article
Pediatrics
Hanni Ronnlund, Marko Elovainio, Irina Virtanen, Anna-Riitta Heikkila, Hanna Raaska, Helena Lapinleimu
Summary: Child eveningness is associated with negative effects on parental sleep quality. Morning-type children decrease the risk of parental sleeping problems at follow-up, compared to evening-type children. Additionally, children with an intermediate chronotype decrease the risk of maternal sleeping problems at follow-up. Parents of evening-type children experience more sleeping problems in the follow-up.
Article
Biology
Lucia Castelli, Letizia Galasso, Antonino Mule, Andrea Ciorciari, Fabio Esposito, Eliana Roveda, Angela Montaruli
Summary: This study found that female and Evening-type university students had worse sleep quality, while male and Morning-type students had better sleep quality. However, there were no significant differences in sleep quality based on physical activity levels. The study also revealed that physical activity had a positive impact on sleep quality for Morning-type students.
CHRONOBIOLOGY INTERNATIONAL
(2023)
Article
Clinical Neurology
Ilona Merikanto, Laura Kortesoja, Christian Benedict, Frances Chung, Jonathan Cedernaes, Colin A. Espie, Charles M. Morin, Yves Dauvilliers, Markku Partinen, Luigi De Gennaro, Yun Kwok Wing, Ngan Yin Chan, Yuichi Inoue, Kentaro Matsui, Brigitte Holzinger, Giuseppe Plazzi, Sergio Arthuro Mota-Rolim, Damien Leger, Thomas Penzel, Bjorn Bjorvatn
Summary: During the COVID-19 pandemic, evening-types experienced poorer mental health, well-being, and quality of life compared to other circadian types. They also reported delayed sleep-wake schedules, increased sleep duration, and more severe sleep problems. Meanwhile, morning-types were less vulnerable to sleep changes and experienced protection from most sleep problems.
Article
Hospitality, Leisure, Sport & Tourism
Li -Jung Chen, Mark Hamer, Yun-Ju Lai, Bo-Huei Huang, Po-Wen Ku, Emmanuel Stamatakis
Summary: Long sleep duration, difficulty falling asleep, and use of sleeping medication are associated with a higher risk of death. Being physically active at a moderate intensity for 25-65 minutes per day eliminates these detrimental associations.
JOURNAL OF SPORT AND HEALTH SCIENCE
(2022)
Article
Multidisciplinary Sciences
Peter P. Ujma, Csenge G. Horvath, Robert Bodizs
Summary: A survey of Hungarian adults found that the timing of daily activity is influenced by demographic and health-related factors such as age, sex, and socioeconomic status. The study also identified social jetlag and certain disorders as being associated with an individual's chronotype, while no causal relationship was found between light exposure and mental health.
SCIENTIFIC REPORTS
(2023)
Article
Psychology, Developmental
Juan F. Diaz Morales, Cristina Escribano, Yaiza Puig-Navarro, Konrad S. Jankowski
Summary: This study examined the contribution of biological and psychosocial factors to the shift towards eveningness in early adolescence. Results showed that girls were more likely to experience this shift compared to boys, and the shift was related to more advanced pubertal development and more conflicts in the family.
JOURNAL OF YOUTH AND ADOLESCENCE
(2023)
Article
Clinical Neurology
Lauren D. Asarnow, Caitlin E. Gasperetti, Nicole B. Gumport, Allison G. Harvey
Summary: Adolescent internet use in the late night and mid-night is common and may be motivated by desires for social connection, boredom/avoidance, or maladaptive behaviors. Late-night and middle-of-the-night internet use is associated with higher internalizing disorder symptoms.
JOURNAL OF CLINICAL SLEEP MEDICINE
(2021)
Article
Clinical Neurology
Kelly Sansom, Amy Reynolds, Satvinder S. Dhaliwal, Jennifer Walsh, Kathleen Maddison, Bhajan Singh, Peter Eastwood, Nigel McArdle
Summary: This study aimed to explore the associations between different chronotypes and sleep apnea and blood pressure. It found that individuals with a morning chronotype and sleep apnea had higher systolic and diastolic blood pressure compared to those with an evening or intermediate chronotype. Assessing chronotype may enhance the assessment of hypertension risk in patients with sleep apnea.
JOURNAL OF SLEEP RESEARCH
(2023)
Article
Biology
Marco Costa, Matteo Re
Summary: The study compared sleep quality and chronotype distribution between highly trained alpine skiers and a control group. The results showed that alpine skiers had a higher percentage of morningness chronotype compared to the control group. The quality and quantity of sleep in alpine skiers were within the normal range.
CHRONOBIOLOGY INTERNATIONAL
(2023)
Article
Psychology, Developmental
Arcady A. Putilov, Dmitry S. Sveshnikov, Zarina B. Bakaeva, Elena B. Yakunina, Yuri P. Starshinov, Vladimir Torshin, Nikolay N. Alipov, Olga Sergeeva, Elena A. Trutneva, Michael M. Lapkin, Zhanna N. Lopatskaya, Roman O. Budkevich, Elena Budkevich, Alexandra N. Puchkova, Vladimir B. Dorokhov
Summary: This study found that female university students are more likely to feel sleepy compared to male students and have a greater need for longer sleep, potentially making them more susceptible to weekday sleep loss. Therefore, the negative effects of reduced sleep duration may be more common and more detrimental among female students.
JOURNAL OF ADOLESCENCE
(2021)
Article
Psychology, Developmental
Sara Sammallahti, Elisa Holmlund-Suila, Runyu Zou, Saara Valkama, Jenni Rosendahl, Maria Enlund-Cerullo, Helena Hauta-Alus, Marius Lahti-Pulkkinen, Hanan El Marroun, Henning Tiemeier, Outi Makitie, Sture Andersson, Katri Raikkonen, Kati Heinonen
Summary: Higher maternal vitamin D concentration during pregnancy is associated with better child mental health, particularly in relation to negative affectivity, a trait indicating increased risk of psychopathology. The study found that higher maternal early/mid-pregnancy vitamin D levels were associated with lower negative affectivity in infants, while cord blood vitamin D levels showed less clear associations. These findings suggest that maternal vitamin D status during early- and mid-pregnancy may play a role in the behavioral development of offspring.
EUROPEAN CHILD & ADOLESCENT PSYCHIATRY
(2023)
Review
Pediatrics
Rachel Robinson, Polina Girchenko, Anna Pulakka, Kati Heinonen, Anna Lahdepuro, Marius Lahti-Pulkkinen, Petteri Hovi, Marjaana Tikanmaki, Peter Bartmann, Aulikki Lano, Lex W. Doyle, Peter J. Anderson, Jeanie L. Y. Cheong, Brian A. Darlow, Lianne J. Woodward, L. John Horwood, Marit S. Indredavik, Kari Anne Evensen, Neil Marlow, Samantha Johnson, Marina Goulart de Mendonca, Eero Kajantie, Dieter Wolke, Katri Raikkonen
Summary: This study examined the differences in ADHD symptoms and diagnosis between preterm and term-born adults and found that while preterm adults may not report higher levels of ADHD symptoms, they have a higher risk of receiving an ADHD diagnosis in adulthood.
PEDIATRIC RESEARCH
(2023)
Article
Psychology, Developmental
Anna Lahdepuro, Marius Lahti-Pulkkinen, Riikka Pyhala, Soile Tuovinen, Jari Lahti, Kati Heinonen, Hannele Laivuori, Pia M. Villa, Rebecca M. Reynolds, Eero Kajantie, Polina Girchenko, Katri Raikkonen
Summary: The study found that positive maternal mental health during pregnancy is associated with a reduced risk of mental and behavioral disorders in children. This association is also seen in children of mothers facing mental health issues.
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
(2023)
Article
Clinical Neurology
Yaping Liu, Eemil Partinen, Ngan Yin Chan, Yves Dauvilliers, Yuichi Inoue, Luigi De Gennaro, Giuseppe Plazzi, Courtney J. Bolstad, Michael R. Nadorff, Ilona Merikanto, Bjorn Bjorvatn, Fang Han, Bin Zhang, Ana Suely Cunha, Sergio Mota-Rolim, Damien Leger, Kentaro Matsui, Colin A. Espie, Frances Chung, Charles M. Morin, Mariusz Sieminski, Penzel Thomas, Brigitte Holzinger, Markku Partinen, Yun Kwok Wing
Summary: This study investigated the prevalence and correlates of dream-enactment behaviours during the COVID-19 pandemic and found a higher percentage of dream-enactment behaviours among individuals with COVID-19 and certain risk factors such as young age, male sex, smoking, alcohol consumption, higher physical activity level, nightmares, COVID-19 diagnosis, olfactory impairment, obstructive sleep apnea symptoms, mood, and post-traumatic stress disorder features. Further research is needed to explore the potential neurodegenerative effects of COVID-19.
JOURNAL OF SLEEP RESEARCH
(2023)
Article
Psychology, Social
Sointu Leikas, Marius Lahti-Pulkkinen, Katri Raikkonen
Summary: This study investigated the effects of parenthood on mothers' personality development and found that mothers experienced changes in neuroticism and extraversion from early pregnancy to 6 months post-partum. Furthermore, mother-perceived child difficult temperament attenuated desirable personality change and amplified the increases in impulsivity.
EUROPEAN JOURNAL OF PERSONALITY
(2023)
Article
Family Studies
Mari Laakso, Ase Fagerlund, Anu-Katriina Pesonen, Rejane A. O. Figueiredo, Johan G. Eriksson
Summary: This current study used experience sampling to examine the change in daily positive and negative emotions of students participating in the Flourishing Students program. The findings suggest that the program has a positive effect on reducing negative emotions and increasing positive emotions in students.
JOURNAL OF EARLY ADOLESCENCE
(2023)
Article
Pediatrics
Suvi Alenius, Eero Kajantie, Reijo Sund, Markku Nurhonen, Peija Haaramo, Pieta Nasanen-Gilmore, Marja Vaarasmaki, Sakari Lemola, Katri Raikkonen, Daniel D. Schnitzlein, Dieter Wolke, Mika Gissler, Petteri Hovi
Summary: This population-based study found that individuals born preterm have a lower risk of sexually transmitted infections and teenage pregnancies, but a higher risk of payment defaults. Extremely preterm individuals have a lower risk of criminal offending, whereas very preterm individuals have a higher risk of payment defaults.
JOURNAL OF PEDIATRICS
(2023)
Article
Clinical Neurology
Ilona Merikanto, Yves Dauvilliers, Frances Chung, Yun Kwok Wing, Luigi De Gennaro, Brigitte Holzinger, Bjorn Bjorvatn, Charles M. Morin, Thomas Penzel, Christian Benedict, Adrijana Koscec Bjelajac, Ngan Yin Chan, Colin A. Espie, Harald Hrubos-Strom, Yuichi Inoue, Maria Korman, Anne-Marie Landtblom, Damien Leger, Kentaro Matsui, Sergio Mota-Rolim, Michael R. Nadorff, Giuseppe Plazzi, Catia Reis, Juliana Yordanova, Markku Partinen
Summary: An international survey study reveals that post-acute sequelae of COVID-19 symptoms are more prevalent among severe cases and long-lasting sleep problems are at the core of these symptoms. Understanding the importance of sleep-related symptoms has clinical relevance in diagnosing and treating long-COVID.
JOURNAL OF SLEEP RESEARCH
(2023)
Article
Biology
Bjorn Bjorvatn, Ilona Merikanto, Catia Reis, Maria Korman, Adrijana Koscec Bjelajac, Brigitte Holzinger, Luigi De Gennaro, Yun Kwok Wing, Charles M. Morin, Colin A. Espie, Christian Benedict, Anne-Marie Landtblom, Kentaro Matsui, Harald Hrubos-Strom, Sergio Mota-Rolim, Michael R. Nadorff, Giuseppe Plazzi, Rachel Ngan Yin Chan, Markku Partinen, Yves Dauvilliers, Frances Chung, Ingeborg Forthun
Summary: The present study aimed to investigate the relationship between shift/night work and face-to-face work with the prevalence and severity of COVID-19. The results showed that shift/night work was not associated with an increased risk of COVID-19, but shift/night workers reported more severe disease when infected. Face-to-face work was associated with an increased risk of COVID-19, but not with higher disease severity.
CHRONOBIOLOGY INTERNATIONAL
(2023)
Article
Psychology, Developmental
Dieter Wolke, Nicole Baumann, Julia Jaekel, Riikka Pyhala, Kati Heinonen, Katri Raikkonen, Christian Sorg, Ayten Bilgin
Summary: This study examined the long-term associations between multiple or persistent regulatory problems and behavioral problems in adulthood. The results showed that individuals who had early multiple or persistent regulatory problems reported more internalizing, externalizing, and total behavioral problems in young adulthood. Screening for early regulatory problems could help identify children at risk for later behavioral problems.
JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY
(2023)
Article
Clinical Neurology
Anna M. Abdollahi, Xinyue Li, Ilona Merikanto, Marja H. Leppanen, Henna Vepsalainen, Reetta Lehto, Carola Ray, Maijaliisa Erkkola, Eva Roos
Summary: This study compared weekday and weekend sleep in relation to weight status among preschool-aged children. Actigraphy measures were more accurate than parent reports. Sleep timing, such as earlier sleep onset and midpoint, was associated with a higher body mass index in children.
JOURNAL OF SLEEP RESEARCH
(2023)
Article
Pediatrics
Ingrid Marie Husby Hollund, Kristina Anna Djupvik Aakvik, Silje Dahl Benum, Sigrid Hegna Ingvaldsen, Stian Lydersen, Marjaana Tikanmaki, Petteri Hovi, Katri Raikkonen, Eero Kajantie, Samantha Johnson, Neil Marlow, Nicole Baumann, Dieter Wolke, Marit S. Indredavik, Kari Anne I. Evensen
Summary: The associations between mental health, pain, and tiredness in adults are independent of gestation or birthweight. Further research should explore other potential mechanisms to explain the increased risk of mental health problems in the preterm population.
Article
Clinical Neurology
Tomi Sarkanen, Markku Partinen, Bjorn Bjorvatn, Ilona Merikanto, Christian Benedict, Michael R. Nadorff, Courtney J. Bolstad, Colin Espie, Kentaro Matsui, Frances Chung, Charles M. Morin, Yun Kwok Wing, Thomas Penzel, Taina Macedo, Sergio Mota-Rolim, Brigitte Holzinger, Giuseppe Plazzi, Luigi De Gennaro, Anne-Marie Landtblom, Yuichi Inoue, Mariuz Sieminski, Damien Leger, Yves Dauvilliers
Summary: The COVID-19 pandemic and related restriction measures have led to an increase in excessive daytime sleepiness, excessive quantity of sleep, and fatigue. Self-reported cases of COVID-19 are particularly associated with these sleep problems. Shorter sleep duration than desired, depressive symptoms, use of hypnotics, and having reported COVID-19 are strong predictors of excessive daytime sleepiness.
Article
Psychology, Developmental
Anna Lahdepuro, Marius Lahti-Pulkkinen, Polina Girchenko, Pia M. Villa, Kati Heinonen, Jari Lahti, Riikka Pyhala, Hannele Laivuori, Eero Kajantie, Katri Raikkonen
Summary: Positive maternal mental health during pregnancy has a positive impact on children's psychiatric problems. This study found that higher positive maternal mental health scores during pregnancy were associated with lower total psychiatric problem scores in both early and late childhood.
DEVELOPMENT AND PSYCHOPATHOLOGY
(2023)
Article
Clinical Neurology
Anna Perkio, Ilona Merikanto, Katri Kantojarvi, Tiina Paunio, Nasa Sinnott-Armstrong, Samuel E. Jones, Hanna M. Ollila
Summary: Polygenic risk scores (PRSs) for sleep traits were generated using summary data from genome-wide association studies and tested in two independent Finnish population cohorts. The PRSs were found to be associated with their respective sleep traits, and there was a significant difference in reported sleep duration between the extremes of the PRS. These findings suggest that sleep-related PRSs are portable across cohorts and can be useful in studying disease and trait associations.
Article
Clinical Neurology
Melanie Strauss, Lucie Griffon, Maxime Elbaz, Isabelle Arnulf, Mounir Chennaoui, Damien Leger
Summary: This study examines decision-making impairments in individuals with central disorders of hypersomnolence (CDH), specifically narcolepsy type 1 (NT1). The results suggest that both NT1 and other CDH patients have decreased learning abilities to avoid losses, which is associated with alterations in vigilance. The study provides new insights into the nature of decision-making impairments in CDH and suggests the potential for minimizing these alterations by restoring adequate vigilance.
Article
Clinical Neurology
Kyriakos Dimitriadis, Christina Stathakopoulou, Nikolaos Pyrpyris, Eirini Beneki, Elena Adamopoulou, Stergios Soulaidopoulos, Ioannis Leontsinis, Alexandros Kasiakogias, Aggelos Papanikolaou, Panagiotis Tsioufis, Konstantinos Aznaouridis, Dimitris Tsiachris, Konstantina Aggeli, Konstantinos Tsioufis
Summary: This review provides a comprehensive analysis of the common pathophysiology between sleep disordered breathing (SDB) and mitral regurgitation (MR), and discusses the effects of SDB treatment on MR and the effects of mitral valve surgery or transcatheter repair on obstructive and central sleep apnea (OSA and CSA).
Article
Clinical Neurology
Szu-Yu Hou, Ching-Ju Chiu, Jeanne Laraine Shea, Chih-Liang Wang, Hsiao-Han Tang, Po-Ching Kuo, Yi-Chieh Yang, Chih-Hsing Wu
Summary: The study aimed to examine the effects of age, menopausal status, and symptoms on sleep patterns and circadian rhythms in midlife women. Premenopausal women had the most unstable day-to-day rhythms, and women with more severe symptoms experienced greater sleep problems. Psychological symptoms were the strongest predictors for all sleep parameters.
Article
Clinical Neurology
Ya-Wen Hsiao, Wei-Lun Lin, Yu-Hui Chou, Shin-Huei Liu, Ting-Wei Ernie Liao, Shih-Ann Chen, Li-Wei Lo
Summary: This study aimed to investigate the effects of RDN on heart inflammation associated with COSA. The results suggest that RDN treatment may prevent COSA-associated heart inflammation through the JAK2-STAT3 signaling pathway.
Article
Clinical Neurology
Amy C. Reynolds, Kelly A. Loffler, Nicole Grivell, Brandon W. J. Brown, Robert J. Adams
Summary: This study aimed to understand the experience of sleep disorder diagnosis and treatment in shift workers and propose patient-informed solutions to improve access to health services. The findings showed that there were varied experiences with diagnosis and management, often taking a long time to seek help from healthcare providers after noticing symptoms. The study also identified the need for education and awareness initiatives, convenient screening and referral pathways, and tailored models of care.
Article
Clinical Neurology
Hsi -Chung Chen, Nai-Wei Hsu, Ching-Heng Lin
Summary: This study found a relationship between daytime sleepiness and mortality risk among older adults. The moderating effects of sex and physical function were examined. Specifically, the passive factor predicted mortality risk in women with good muscle power, while the active factor predicted mortality risk in men with good muscle power.
Article
Clinical Neurology
Sean P. A. Drummond, Bei Bei
Summary: This study proposes a parsimonious two-stage model for defining stages of Cognitive Behavioural Therapy for Insomnia (CBT-I) based on Sleep Restriction Therapy (SRT). Using data from a randomized clinical trial, the model helps identify patterns of treatment progression and their association with baseline insomnia severity. The model holds potential for further research on various CBT-I processes that are currently not fully understood.
Article
Clinical Neurology
Janet Jezkova, Karel Sonka, Jakub Kreisinger, Petra Prochazkova, Helena Tlaskalova-Hogenova, Sona Nevsimalova, Jitka Buskova, Radana Merkova, Tereza Dvorakova, Iva Prihodova, Simona Dostalova, Radka Roubalova
Summary: In recent years, there has been a growing interest in the influence of gut microbiota on sleep physiology. The gut microbiota affects the central nervous system and circadian rhythms, and can be associated with sleep disorders. This study observed the gut microbiota composition of patients with different types of narcolepsy and idiopathic hypersomnia, and found changes in beta diversity in these patient groups compared to healthy controls. However, after adjusting for confounding factors, the differences were no longer statistically significant. The study suggests that using metabolomics and proteomics approaches to study the role of microbiota in sleep disorders may be beneficial.
Article
Clinical Neurology
Mauro Manconi, Linda C. van der Gaag, Francesca Mangili, Corrado Garbazza, Silvia Riccardi, Christian Cajochen, Susanna Mondini, Francesca Furia, Elena Zambrelli, Simone Baiardi, Alessandra Giordano, Nicola Rizzo, Cristina Fonti, Elsa Viora, Armando D'Agostino, Alessandro Cicolin, Fabio Cirignotta, Daniele Aquilino, Alessandra Barassi, Renata del Giudice, Giulia Fior, Orsola Gambini, Barbara Giordano, Alma Martini, Chiara Serrati, Rossana Stefanelli, Silvio Scarone, Mariapaola Canevini, Valentina Fanti, Hans-Christian Stein, Anna Maria Marconi, Erica Raimondo, Emanuela Viglietta, Rossella Santoro, Giuliana Simonazzi, Alessandra Bianconcini, Francesco Meani, Nicoletta Piazza, Filippos Filippakos, Thomas Gyr
Summary: The Life-ON study provides the largest polysomnographic dataset coupled with longitudinal subjective assessments of sleep quality in pregnant women to date. Sleep disorders are highly frequent and distributed differently during pregnancy and postpartum. Routine assessment of sleep disturbances in the perinatal period is necessary to improve early detection and clinical management.
Article
Clinical Neurology
Zhihua Huang, Anqi Duan, Zhihui Zhao, Qing Zhao, Yi Zhang, Xin Li, Sicheng Zhang, Luyang Gao, Chenhong An, Qin Luo, Zhihong Liu
Summary: This study aims to investigate pulmonary arterial hypertension (PAH) phenotypes and their prognostic implications by clustering overnight cardiorespiratory signals in PAH patients. Three distinct clusters were identified, with patients in Cluster 3 exhibiting worse clinical outcomes. The presence of nocturnal hypoxemia and obstructive sleep apnea (OSA) in PAH patients was associated with increased risk of clinical worsening. Tailored management strategies addressing both PAH and nocturnal hypoxemia may improve clinical outcomes.
Article
Clinical Neurology
Yudan Lv, Yujun Wen, Ramalingam Vetrivelan, Jun Lu
Summary: This study demonstrated that the projections from the pontine parabrachial nucleus (PB) to the basal forebrain (BF) and medial septum (MS) can activate the cerebral cortex and hippocampus, providing important insights into the activities of these brain regions during the sleep-wake cycle.
Article
Clinical Neurology
Annika M. Myers, Megan E. Rech, Bengi Baran, Cara Palmer, Dimitrios Mylonas, Candice A. Alfano
Summary: This study found that N2 sleep spindles are associated with emotional functioning in school-aged children. Higher spindle density is related to decreased state-based emotional arousal towards negative affective images, and higher spindle peak frequency is associated with greater use of the positive emotion regulatory strategy of savoring.
Article
Clinical Neurology
Hung Youl Seok, Yong Won Cho
Summary: This study investigated the long-term impact of dopamine agonist treatment on altered central sensory processing in restless legs syndrome (RLS) patients. The results showed that dopamine agonist treatment effectively reduced RLS symptoms but did not reverse the altered central sensory processing observed on testing. These findings suggest that RLS pathophysiology is multifactorial and not solely driven by dopaminergic dysfunction.