Improved Insulin Sensitivity With Angiotensin Receptor Neprilysin Inhibition in Individuals With Obesity and Hypertension

Pharmacodynamic and Pharmacokinetic Profiles of Sacubitril/Valsartan (LCZ696) in Patients with Heart Failure and Reduced Ejection Fraction

(2016) Zhanna Kobalava et al.   Cardiovascular Therapeutics

Obesity-Induced Hypertension: Interaction of Neurohumoral and Renal Mechanisms

(2015) J. E. Hall et al.   CIRCULATION RESEARCH

Defective Natriuretic Peptide Receptor Signaling in Skeletal Muscle Links Obesity to Type 2 Diabetes

(2015) Marine Coué et al.   DIABETES

Treatment with Sildenafil Improves Insulin Sensitivity in Prediabetes: A Randomized, Controlled Trial

(2015) Claudia E. Ramirez et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Contribution of Major Lifestyle Risk Factors for Incident Heart Failure in Older Adults

(2015) Liana C. Del Gobbo et al.   JACC-Heart Failure

Efficacy and Safety of LCZ696, a First-in-Class Angiotensin Receptor Neprilysin Inhibitor, in Asian Patients With Hypertension

(2014) Kazuomi Kario et al.   HYPERTENSION

Angiotensin–Neprilysin Inhibition versus Enalapril in Heart Failure

(2014) John J.V. McMurray et al.   NEW ENGLAND JOURNAL OF MEDICINE

Atrial Natriuretic Peptide and Type 2 Diabetes Development – Biomarker and Genotype Association Study

(2014) Amra Jujić et al.   PLoS One

Natriuretic peptides enhance the oxidative capacity of human skeletal muscle

(2012) Stefan Engeli et al.   JOURNAL OF CLINICAL INVESTIGATION

Joint statement of the European Association for the Study of Obesity and the European Society of Hypertension

(2012) Jens Jordan et al.   JOURNAL OF HYPERTENSION

Role of renin–angiotensin–aldosterone system in adipose tissue dysfunction

(2012) Fei Jing et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

The Renin-Angiotensin System in the Pathophysiology of Type 2 Diabetes

(2012) Gijs H. Goossens   Obesity Facts

Kinin B1 Receptor in Adipocytes Regulates Glucose Tolerance and Predisposition to Obesity

(2012) Marcelo A. Mori et al.   PLoS One

Valsartan Improves  -Cell Function and Insulin Sensitivity in Subjects With Impaired Glucose Metabolism: A randomized controlled trial

(2011) N. J. van der Zijl et al.   DIABETES CARE

Low Plasma Level of Atrial Natriuretic Peptide Predicts Development of Diabetes: The Prospective Malmö Diet and Cancer Study

(2011) Martin Magnusson et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Skeletal Muscle Fatty Acid Handling in Insulin Resistant Men

(2011) Anneke M.J. van Hees et al.   Obesity

Metabolic Actions Could Confound Advantageous Effects of Combined Angiotensin II Receptor and Neprilysin Inhibition

(2010) Andreas L. Birkenfeld et al.   HYPERTENSION

Neprilysin, obesity and the metabolic syndrome

(2010) K F Standeven et al.   INTERNATIONAL JOURNAL OF OBESITY

Lipid-induced insulin resistance: unravelling the mechanism

(2010) Varman T Samuel et al.   LANCET

Effect of Valsartan on the Incidence of Diabetes and Cardiovascular Events

(2010)   NEW ENGLAND JOURNAL OF MEDICINE

Natriuretic Peptides/cGMP/cGMP-Dependent Protein Kinase Cascades Promote Muscle Mitochondrial Biogenesis and Prevent Obesity

(2009) Kazutoshi Miyashita et al.   DIABETES

Pharmacokinetics and Pharmacodynamics of LCZ696, a Novel Dual-Acting Angiotensin Receptor-Neprilysin Inhibitor (ARNi)

(2009) Jessie Gu et al.   JOURNAL OF CLINICAL PHARMACOLOGY

CARDIOVASCULAR AND METABOLIC EFFECTS OF OBESITY

(2008) Margaret J Morris   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Atrial Natriuretic Peptide Induces Postprandial Lipid Oxidation in Humans

(2008) A. L. Birkenfeld et al.   DIABETES

Endothelin-1 stimulates human adipocyte lipolysis through the ETA receptor

(2008) A K S Eriksson et al.   INTERNATIONAL JOURNAL OF OBESITY

Effect of bradykinin metabolism inhibitors on evoked hypotension in rats: rank efficacy of enzymes associated with bradykinin-mediated angioedema

(2007) R M Fryer et al.   BRITISH JOURNAL OF PHARMACOLOGY