Circular RNA circ-LDLRAD3 serves as an oncogene to promote non-small cell lung cancer progression by upregulating SLC1A5 through sponging miR-137

Ablation of the ASCT2 (SLC1A5) gene encoding a neutral amino acid transporter reveals transporter plasticity and redundancy in cancer cells

(2019) Angelika Bröer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TEA Domain Transcription Factor 1 (TEAD1) Promotes Smooth Muscle Cell Proliferation through Up-Regulating SLC1A5-Mediated Glutamine Uptake

(2019) Islam Osman et al.   CIRCULATION RESEARCH

Metformin inhibits PPARδ agonist-mediated tumor growth by reducing Glut1 and SLC1A5 expressions of cancer cells

(2019) Jiajun Ding et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Circular RNA profiling identified as a biomarker for predicting the efficacy of Gefitinib therapy for non-small cell lung cancer

(2019) Yu-Tao Liu et al.   Journal of Thoracic Disease

The circRNA circPTPRA suppresses epithelial-mesenchymal transitioning and metastasis of NSCLC cells by sponging miR-96-5p

(2019) Siliang Wei et al.   EBioMedicine

MicroRNA-330-3p promotes brain metastasis and epithelial-mesenchymal transition via GRIA3 in non-small cell lung cancer

(2019) Chunhua Wei et al.   Aging-US

Causes and Consequences of A Glutamine Induced Normoxic HIF1 Activity for the Tumor Metabolism

(2019) Matthias Kappler et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Downregulation of circular RNA circ-LDLRAD3 suppresses pancreatic cancer progression through miR-137-3p/PTN axis

(2019) Jun Yao et al.   LIFE SCIENCES

Small nucleolar RNA host gene 1 promotes development and progression of colorectal cancer through negative regulation of miR‐137

(2019) Yang Fu et al.   MOLECULAR CARCINOGENESIS

Identification of microRNAs involved in pathways which characterize the expression subtypes of NSCLC

(2019) Ann Rita Halvorsen et al.   Molecular Oncology

Nivolumab plus Ipilimumab in Advanced Non–Small-Cell Lung Cancer

(2019) Matthew D. Hellmann et al.   NEW ENGLAND JOURNAL OF MEDICINE

Circular RNA PIP5K1A promotes colon cancer development through inhibiting miR-1273a

(2019) Qu Zhang et al.   WORLD JOURNAL OF GASTROENTEROLOGY

Circular RNA hsa_circ_0023404 promotes proliferation, migration and invasion in non-small cell lung cancer by regulating miR-217/ZEB1 axis

(2019) Chengjun Liu et al.   OncoTargets and Therapy

Long noncoding RNA ABHD11-AS1 functions as a competing endogenous RNA to regulate papillary thyroid cancer progression by miR-199a-5p/SLC1A5 axis

(2019) Xi Zhuang et al.   Cell Death & Disease

MicroRNA-608 Promotes Apoptosis in Non-Small Cell Lung Cancer Cells Treated With Doxorubicin Through the Inhibition of TFAP4

(2019) Yi-Fei Wang et al.   Frontiers in Genetics

Diverse Roads Taken by 13C-Glucose-Derived Metabolites in Breast Cancer Cells Exposed to Limiting Glucose and Glutamine Conditions

(2019) Gkiouli et al.   Cells

Pemetrexed exposure predicts toxicity in advanced non–small-cell lung cancer: A prospective cohort study

(2019) S. Visser et al.   EUROPEAN JOURNAL OF CANCER

Circular RNA circ-PRMT5 facilitates non-small cell lung cancer proliferation through upregulating EZH2 via sponging miR-377/382/498

(2019) Yuan Wang et al.   GENE

Upregulated circRNA ARHGAP10 Predicts an Unfavorable Prognosis in NSCLC through Regulation of the miR-150-5p/GLUT-1 Axis

(2019) Mingming Jin et al.   Molecular Therapy-Nucleic Acids

Crosstalk of mRNA, miRNA, lncRNA, and circRNA and Their Regulatory Pattern in Pulmonary Fibrosis

(2019) Changye Li et al.   Molecular Therapy-Nucleic Acids

Significance of Mir-15a-5p and Cnksr3 as Novel Prognostic Biomarkers in Non-Small Cell Lung Cancer

(2018) Sercan Ergun et al.   Anti-Cancer Agents in Medicinal Chemistry

miR-137 regulates ferroptosis by targeting glutamine transporter SLC1A5 in melanoma

(2018) Meiying Luo et al.   CELL DEATH AND DIFFERENTIATION

Let-7 Suppresses B Cell Activation through Restricting the Availability of Necessary Nutrients

(2018) Shuai Jiang et al.   Cell Metabolism

Knockdown of LncRNA-XIST Suppresses Proliferation and TGF-β1-Induced EMT in NSCLC Through the Notch-1 Pathway by Regulation of miR-137

(2018) Xi Wang et al.   Genetic Testing and Molecular Biomarkers

Overexpression of SLC1a5 in lymph node metastases outperforms assessment in the primary as a negative prognosticator in non-small cell lung cancer

(2018) Agnes Csanadi et al.   PATHOLOGY

MicroRNA‑137‑regulated AKT serine/threonine kinase 2 inhibits tumor growth and sensitizes cisplatin in patients with non‑small cell lung cancer

(2018) Zhuming Lu et al.   Oncology Letters

Circular RNA circ-LDLRAD3 as a biomarker in diagnosis of pancreatic cancer

(2017) Fan Yang et al.   WORLD JOURNAL OF GASTROENTEROLOGY

miR-137 inhibits the proliferation of human non-small cell lung cancer cells by targeting SRC3

(2017) Ruilin Chen et al.   Oncology Letters

Effects of targeting SLC1A5 on inhibiting gastric cancer growth and tumor development in vitro and in vivo

(2017) Jian Lu et al.   Oncotarget

Epigenetic silencing of microRNA-137 enhances ASCT2 expression and tumor glutamine metabolism

(2017) J Dong et al.   Oncogenesis

Targeting SLC1a5-mediated glutamine dependence in non-small cell lung cancer

(2015) Mohamed Hassanein et al.   INTERNATIONAL JOURNAL OF CANCER

ASCT2/SLC1A5 controls glutamine uptake and tumour growth in triple-negative basal-like breast cancer

(2015) M van Geldermalsen et al.   ONCOGENE

SLC1A5 Mediates Glutamine Transport Required for Lung Cancer Cell Growth and Survival

(2012) M. Hassanein et al.   CLINICAL CANCER RESEARCH