Screen identifies DYRK1B network as mediator of transcription repression on damaged chromatin

Perfecting DNA double-strand break repair on transcribed chromatin

(2020) Xin Yi Tan et al.   Essays in Biochemistry

Single-molecule imaging of transcription at damaged chromatin

(2019) Alexandra C. Vítor et al.   Science Advances

A Snapshot on the Cis Chromatin Response to DNA Double-Strand Breaks

(2019) Thomas Clouaire et al.   TRENDS IN GENETICS

Metaproteomics reveals potential mechanisms by which dietary resistant starch supplementation attenuates chronic kidney disease progression in rats

(2019) Boris L. Zybailov et al.   PLoS One

Heterozygous mutations cause genetic instability in a yeast model of cancer evolution

(2019) Miguel C. Coelho et al.   NATURE

WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks

(2019) Pierre Caron et al.   GENES & DEVELOPMENT

De novo phosphorylation of H2AX by WSTF regulates transcription-coupled homologous recombination repair

(2019) Jae-Hoon Ji et al.   NUCLEIC ACIDS RESEARCH

Regional Gene Repression by DNA Double-Strand Breaks in G1 Phase Cells

(2019) Caitlin E. Purman et al.   MOLECULAR AND CELLULAR BIOLOGY

MDC1 methylation mediated by lysine methyltransferases EHMT1 and EHMT2 regulates active ATM accumulation flanking DNA damage sites

(2018) Sugiko Watanabe et al.   Scientific Reports

Repression of Transcription at DNA Breaks Requires Cohesin throughout Interphase and Prevents Genome Instability

(2018) Cornelia Meisenberg et al.   MOLECULAR CELL

The OTUD5–UBR5 complex regulates FACT-mediated transcription at damaged chromatin

(2018) Angelo de Vivo et al.   NUCLEIC ACIDS RESEARCH

A wake-up call to quiescent cancer cells - potential use of DYRK1B inhibitors in cancer therapy

(2017) Walter Becker   FEBS Journal

Transcription-Coupled DNA Double-Strand Break Repair: Active Genes Need Special Care

(2017) Aline Marnef et al.   JOURNAL OF MOLECULAR BIOLOGY

Transcription and DNA Damage: Holding Hands or Crossing Swords?

(2017) Giuseppina D'Alessandro et al.   JOURNAL OF MOLECULAR BIOLOGY

Genome-wide mapping of long-range contacts unveils clustering of DNA double-strand breaks at damaged active genes

(2017) François Aymard et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Dual-utility NLS drives RNF169-dependent DNA damage responses

(2017) Liwei An et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

G9a coordinates with the RPA complex to promote DNA damage repair and cell survival

(2017) Qiaoyan Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PARP, transcription and chromatin modeling

(2017) Melanija Posavec Marjanović et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

A damaged genome’s transcriptional landscape through multilayered expression profiling around in situ-mapped DNA double-strand breaks

(2017) Fabio Iannelli et al.   Nature Communications

Genome-wide mapping of long-range contacts unveils clustering of DNA double-strand breaks at damaged active genes

(2017) François Aymard et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Protein-lysine methyltransferases G9a and GLP1 promote responses to DNA damage

(2017) Vasudeva Ginjala et al.   Scientific Reports

BMI1–UBR5 axis regulates transcriptional repression at damaged chromatin

(2016) Anthony Sanchez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of DYRK1B as a substrate of ERK1/2 and characterisation of the kinase activity of DYRK1B mutants from cancer and metabolic syndrome

(2015) Anne L. Ashford et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination

(2015) Fade Gong et al.   GENES & DEVELOPMENT

Transcriptional Elongation Factor ENL Phosphorylated by ATM Recruits Polycomb and Switches Off Transcription for DSB Repair

(2015) Ayako Ui et al.   MOLECULAR CELL

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

DNA Damage Response and Metabolic Disease

(2014) Ippei Shimizu et al.   Cell Metabolism

Nuclear position dictates DNA repair pathway choice

(2014) Charlène Lemaître et al.   GENES & DEVELOPMENT

Requirement for PBAF in Transcriptional Repression and Repair at DNA Breaks in Actively Transcribed Regions of Chromatin

(2014) Andreas Kakarougkas et al.   MOLECULAR CELL

Transcriptionally active chromatin recruits homologous recombination at DNA double-strand breaks

(2014) François Aymard et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A Form of the Metabolic Syndrome Associated with Mutations in DYRK1B

(2014) Ali R. Keramati et al.   NEW ENGLAND JOURNAL OF MEDICINE

Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

(2013) Edward Y Chen et al.   BMC BIOINFORMATICS

Mirk/dyrk1B Kinase in Ovarian Cancer

(2013) Eileen Friedman   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The ATM protein kinase: regulating the cellular response to genotoxic stress and more

(2013) Yosef Shiloh et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination

(2013) Jiangbo Tang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Emerging role of DYRK family protein kinases as regulators of protein stability in cell cycle control

(2012) Walter Becker   CELL CYCLE

New lysine methyltransferase drug targets in cancer

(2012) Tobias Wagner et al.   NATURE BIOTECHNOLOGY

DNAPKcs-dependent arrest of RNA polymerase II transcription in the presence of DNA breaks

(2012) Tibor Pankotai et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

H3K9 methyltransferase G9a and the related molecule GLP

(2011) Y. Shinkai et al.   GENES & DEVELOPMENT

A chemical probe selectively inhibits G9a and GLP methyltransferase activity in cells

(2011) Masoud Vedadi et al.   Nature Chemical Biology

REVIGO Summarizes and Visualizes Long Lists of Gene Ontology Terms

(2011) Fran Supek et al.   PLoS One

ATM-Dependent Chromatin Changes Silence Transcription In cis to DNA Double-Strand Breaks

(2010) Niraj M. Shanbhag et al.   CELL

High-resolution profiling of γH2AX around DNA double strand breaks in the mammalian genome

(2010) Jason S Iacovoni et al.   EMBO JOURNAL

The Kinase Mirk/dyrk1B: A Possible Therapeutic Target in Pancreatic Cancer

(2010) Eileen Friedman   Cancers