4.7 Article

Consequences of various housing systems and dietary supplementation of thymol, carvacrol, and euganol on performance, egg quality, blood chemistry, and antioxidant parameters

期刊

POULTRY SCIENCE
卷 99, 期 9, 页码 4384-4397

出版社

ELSEVIER
DOI: 10.1016/j.psj.2020.05.028

关键词

essential oil; egg production; hen; housing system; blood

资金

  1. King Saud University [RSP-2020/149]
  2. King Saud University, Riyadh, Saudi Arabia

向作者/读者索取更多资源

The present work was carried out to investigate the influences of housing system and dietary essential oils (EOs) supplementation to laying hens on the productive performance, egg quality, immunity, antioxidant parameters, and hematology. A factorial arrangement (2 x 4) was performed, including 2 housing systems and 4 different types of EOs (without EOs, thymol, carvacrol, and euganol) during the production stages (from 28-78 wk of age). Birds were randomly divided into 2 groups with each of 2,000 birds. The first group was moved to laying cages while the second group was a floor reared. Each group was randomly divided into 4 groups (5 replicates of 100 birds each): The first were considered as a control group, and the second, third, and fourth groups were treated with thymol, carvacrol, and euganol EO, respectively. The results showed that hens reared in cage system had higher egg weight (P < 0.05), egg production, egg mass, and feed intake and better feed conversion ratio (P < 0.001) than those reared in the floor system. Blood picture values (except white blood cells), phagocytic index, phagocytic activity, and blood chemistry parameters (except calcium, phosphorus, and urea values) of laying hens were not affected (P > 0.05) by housing system. The groups fed EOs showed a rapid improvement (P < 0.001) in the egg production%, egg weight, egg mass, and egg quality. Thymol group had the highest egg production (P < 0.001). Thymol and eugenol groups had the highest egg weight, egg mass, and egg quality(P < 0.001). The groups fed diets containing thymol or eugenol consumed lower feed and had better feed conversion ratio (P < 0.001) than the control group. Immunity indices (phagocytic activity [P < 0.05], avian influenza [AIH5 and AIH9], P < 0.001) were improved with the presence of EOs in the laying hen diet. These results strongly suggest that dietary EO supplementation could be a successful attempt to improve the productive performance, egg quality, and immunity of laying hens.

作者

我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。

评论

主要评分

4.7
评分不足

次要评分

新颖性
-
重要性
-
科学严谨性
-
评价这篇论文

推荐

Article Environmental Sciences

Impact of petroleum industry on goats in Saudi Arabia: heavy metal accumulation, oxidative stress, and tissue injury

Jamaan S. Ajarem, Ahmad K. Hegazy, Gamal A. Allam, Ahmed A. Allam, Saleh N. Maodaa, Ayman M. Mahmoud

Summary: This study evaluated the levels of heavy metals in Plantago ovata and domestic goats in the eastern region of Saudi Arabia, which were influenced by the petroleum industry. The results showed that the petroleum industry increased the levels of lead, cadmium, nickel, and vanadium in both the plant and animal samples, leading to liver and kidney injury, oxidative stress, and upregulation of pro-inflammatory and apoptosis markers.

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2023)

Article Environmental Sciences

Impact of gervital against histopathological, ultrastructural, and biochemical alterations caused by methotrexate or azathioprine in albino rat testis

Manal Abdul-Hamid, Eman S. Abdel-Reheim, Walaa Hegazy, Ahmed A. Allam, Sarah Othman, Haifa ALqhtani, Samraa H. Abdel-Kawi

Summary: This study found that grape seed extract (GSE) can protect the testis from damage caused by Methotrexate (MTX) and azathioprine (AZA), and it has antioxidant effects.

ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH (2023)

Article Chemistry, Multidisciplinary

Green process of biomass waste derived fluorescent carbon quantum dots for biological imaging in vitro and in vivo

Haitao Ren, Yue Yuan, Abdelkader Labidi, Qibing Dong, Ke Zhang, Eric Lichtfouse, Ahmed A. Allam, Jamaan S. Ajarem, Chuanyi Wang

Summary: In the context of the circular economy, biomass waste can be converted into value-added materials and energy to reduce pollution and waste disposal costs. This study developed low-cost and environmentally friendly carbon quantum dots (CQDs) from peach leaf waste, which showed excellent fluorescence properties and stability, making them a potential candidate for biological imaging.

CHINESE CHEMICAL LETTERS (2023)

Review Agriculture, Dairy & Animal Science

Application of herbs and their derivatives in broiler chickens: a review

Majid Rafeeq, Rana Muhammad Bilal, Fiza Batool, Kashif Yameen, Mayada R. Farag, Mahmoud Madkour, Shaaban S. Elnesr, Nahed A. El-Shall, Kuldeep Dhama, Mahmoud Alagawany

Summary: Botanical medicine is an ancient form of medicine that has been used by humans for thousands of years. Recently, phytobiotics, which are phytochemical compounds derived from plants, have been widely investigated and used in veterinary medicine as feed additives for animals, to improve their performance. These phytobiotics include herbs, spices, and essential oils, which contain various active chemicals that can have different modes of action and benefits on animal health and growth.

WORLDS POULTRY SCIENCE JOURNAL (2023)

Review Green & Sustainable Science & Technology

Approaches of Egg Decontamination for Sustainable Food Safety

Bothaina Y. Mahmoud, Doaa A. Semida, Shaaban S. Elnesr, Hamada Elwan, Ensaf A. El-Full

Summary: Eggs are a valuable source of nutrients and can be preserved using thermal and non-thermal techniques to reduce bacterial contamination. Thermal approaches are more effective in reducing the concentration of pathogens on the egg's surface. Combination methods, such as thermoultrasonification, can mitigate negative effects on the egg's functionality. Further research is needed on other decontamination methods for commercial usage and cost considerations.

SUSTAINABILITY (2023)

Article Chemistry, Inorganic & Nuclear

Synthesis of K+ and Na+ Synthetic Sodalite Phases by Low-Temperature Alkali Fusion of Kaolinite for Effective Remediation of Phosphate Ions: The Impact of the Alkali Ions and Realistic Studies

Stefano Bellucci, Mohamed Hamdy Eid, Ilona Fekete, Szucs Peter, Attila Kovacs, Sarah I. Othman, Jamaan S. Ajarem, Ahmed A. Allam, Mostafa R. Abukhadra

Summary: Two sodalite phases, potassium sodalite (K.SD) and sodium sodalite (Na.SD), were synthesized and characterized for their potential in adsorbing PO43- from water. The sodium sodalite phase showed higher surface area, ion-exchange capacity, and PO43- sequestration capacity compared to the potassium sodalite phase. Both phases exhibited spontaneous, homogeneous, and exothermic adsorption reactions, following the Langmuir isotherm and pseudo-first-order kinetics. The sodium sodalite phase had a higher density of active sites and stronger adsorption capability, resulting in complete adsorption of PO43- from water in a shorter time.

INORGANICS (2023)

Article Engineering, Chemical

Catalytic degradation of pharmaceutical and personal care products in aqueous solution by persulfate activated with nanoscale FeCoNi-ternary mixed metal oxides

Yumeng Qi, Mengting Zou, Jamaan S. Ajarem, Ahmed A. Allam, Zunyao Wang, Ruijuan Qu, Feng Zhu, Zongli Huo

Summary: Recently, nanoscale FeCoNi-ternary mixed metal oxides (TMMO) were used to activate persulfate (PS) for degrading pharmaceutical and personal care products (PPCPs). The FeCoNi-TMMO catalyst exhibited high catalytic activity, stability, and recyclability due to the synergistic catalytic effect between the transition metal elements. The FeCoNi-TMMO/PS system showed excellent universality for various PPCPs, and reactive oxygen species played a crucial role in the degradation process.

SEPARATION AND PURIFICATION TECHNOLOGY (2023)

Article Agriculture, Dairy & Animal Science

Influence of Improved Microclimate Conditions on Growth and Physiological Performance of Two Japanese Quail Lines

Ahmed M. M. Emam, Shaaban S. S. Elnesr, Ensaf A. A. El-Full, Bothaina Y. Y. Mahmoud, Hamada Elwan

Summary: This study investigated the influence of adding natural zeolite to Japanese quail litter on microclimate parameters, growth performance, blood gases, and blood biochemical indicators. The results showed that both the treated group and the selected line had better growth performance compared to the untreated group and control line. Adding zeolite improved the microclimate characteristics of the quail litter, leading to better growth performance and health of the birds. Thus, the use of natural zeolite effectively reduces atmospheric ammonia levels in Japanese quail farms.

ANIMALS (2023)

Article Engineering, Biomedical

Synthesis and Biological Activity Evaluations of Green ZnO-Decorated Acid-Activated Bentonite-Mediated Curcumin Extract (ZnO@CU/BE) as Antioxidant and Antidiabetic Agents

Hassan Ahmed Rudayni, Marwa H. Shemy, Malak Aladwani, Lina M. Alneghery, Gasem M. Abu-Taweel, Ahmed A. Allam, Mostafa R. Abukhadra, Stefano Bellucci

Summary: Green ZnO-decorated acid-activated bentonite-mediated curcumin extract (ZnO@CU/BE) is a multifunctional antioxidant and antidiabetic agent prepared using curcumin extract as a reducing and capping reagent. ZnO@CU/BE exhibits enhanced antioxidant properties and potent inhibition effects on enzymes related to diabetes. The structure shows potential as an antioxidant and antidiabetic agent.

JOURNAL OF FUNCTIONAL BIOMATERIALS (2023)

Article Chemistry, Inorganic & Nuclear

Synthesis and Characterization of Green Zinc-Metal-Pillared Bentonite Mediated Curcumin Extract (Zn@CN/BE) as an Enhanced Antioxidant and Anti-Diabetes Agent

Stefano Bellucci, Hassan Ahmed Rudayni, Marwa. H. H. Shemy, Malak Aladwani, Lina. M. M. Alneghery, Ahmed. A. A. Allam, Mostafa. R. R. Abukhadra

Summary: A green zinc-metal-pillared bentonite mediated curcumin extract (Zn@CN/BE) was synthesized as an enhanced antioxidant and antidiabetic agent with remarkable activities. The structure exhibited higher antioxidant and inhibition activities compared to individual components and commercial drugs. The enhancement effect was attributed to the zinc pillaring process, which improved the stability, dispersion, and solubility of the active compounds.

INORGANICS (2023)

Article Food Science & Technology

Cadmium cardiotoxicity is associated with oxidative stress and upregulated TLR-4/NF-kB pathway in rats; protective role of agomelatine

Reem S. Alruhaimi, Emad H. M. Hassanein, May N. Bin-Jumah, Ayman M. Mahmoud

Summary: This study evaluated the protective effects of agomelatine (AGM) against cadmium (Cd)-induced cardiotoxicity in rats and found that AGM modulated the TLR-4/NF-kB pathway and HSP70. The results showed that AGM alleviated Cd-induced myocardial injury, reduced oxidative stress, and enhanced antioxidant effects.

FOOD AND CHEMICAL TOXICOLOGY (2023)

Article Biochemistry & Molecular Biology

Synthesis and Characterization of Methoxy-Exfoliated Montmorillonite Nanosheets as Potential Carriers of 5-Fluorouracil Drug with Enhanced Loading, Release, and Cytotoxicity Properties

Mashael D. Alqahtani, May N. Bin Jumah, Abdulrahman Al-Hashimi, Ahmed A. Allam, Mostafa R. Abukhadra, Stefano Bellucci

Summary: In this study, natural bentonite clay was modified to enhance its drug loading capabilities for 5-fluorouracil. The modification process involved exfoliation of the clay into nanosheets and further functionalization with methanol. The modified carrier (Mth/EXBE) showed higher loading site density and faster drug release compared to the raw clay. Additionally, the cytotoxicity of 5-fluorouracil was significantly enhanced by the modified carriers.

MOLECULES (2023)

Article Biochemistry & Molecular Biology

Insight into the Morphological Properties of Nano-Kaolinite (Nanoscrolls and Nanosheets) on Its Qualification as Delivery Structure of Oxaliplatin: Loading, Release, and Kinetic Studies

Mashael Daghash Alqahtani, Nourhan Nasser, May N. N. Bin Jumah, Saleha A. A. AlZahrani, Ahmed A. A. Allam, Mostafa R. R. Abukhadra, Stefano Bellucci

Summary: Natural kaolinite can be modified into separated single nanosheets (KNs) and scrolled nanoparticles as nanotubes (KNTs). The synthetic nanostructures show advanced oxaliplatin-medication (OXAP) delivery systems. The loading capacity of KNs and KNTs is significantly increased compared to raw kaolinite, and they exhibit classic kinetic and isotherm behaviors. The release of OXAP from KNs and KNTs shows continuous and regulated profiles, with KNTs demonstrating faster release. The cytotoxicity of the synthesized structures is significantly enhanced on cancer cell lines, and they greatly increase the cytotoxicity of OXAP.

MOLECULES (2023)

Article Pharmacology & Pharmacy

Cadmium-induced lung injury is associated with oxidative stress, apoptosis, and altered SIRT1 and Nrf2/HO-1 signaling; protective role of the melatonin agonist agomelatine

Reem S. Alruhaimi, Emad H. M. Hassanein, May N. Bin-Jumah, Ayman M. Mahmoud

Summary: Pre-treatment with Agomelatine (AGM) exerts a protective effect against Cd-induced lung injury by regulating the Nrf2/HO-1 and SIRT1/FOXO3 signaling pathways, thereby exerting antioxidant and anti-apoptotic effects.

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2023)

Article Agriculture, Dairy & Animal Science

Efficacy of Dietary Supplementation with Zinc-Chromium Mixture, Organic Selenium, or Their Combinations on Growth Performance, Carcass Traits, and Blood Profiles of Broilers under Heat Stress Conditions

Abdelhameed S. A. Mohamed, Maha A. Abd El Latif, Eman A. M. Hussein, Enas M. A. Toson, Mohamed Saleh, Dariusz Kokoszynski, Shaaban S. Elnesr, Mohamed Mohany, Salim S. Al-Rejaie, Hamada Elwan

Summary: The need for heat stress mitigation methods has increased due to climate change. Adding trace elements, such as selenium, to chick diets can improve production yield and grill productivity. However, there is limited knowledge on the use of organic selenium in heat-stress situations. This study found that adding organic selenized yeast to broiler diets improves their blood profiles and productivity under heat stress, suggesting that feed additives can reduce the impacts of heat stress on broilers.

ANIMALS (2023)

Article Agriculture, Dairy & Animal Science

Research Note: Preliminary results, first detection of Enterococcus cecorum from environmental samples by streaking on X-Gluc containing selective media

Jesper Tessin, Judith Rohde, Arne Jung, Nicole Kemper, Jochen Schulz

Summary: In this study, samples from poultry house environment and culled birds were collected, and E. cecorum was successfully isolated. The principle of isolating the pathogen by streaking on a chromogenic agar may motivate researchers to investigate transmission routes and optimize biosecurity measures.

POULTRY SCIENCE (2024)

Article Agriculture, Dairy & Animal Science

Prevalence, genomic characteristics, and pathogenicity of fowl adenovirus 2 in Southern China

Junqin Zhang, Zimin Xie, Yanlin Pan, Zuoxin Chen, Yunzhen Huang, Linlin Li, Jiawen Dong, Yong Xiang, Qi Zhai, Minhua Sun, Xingying Li, Shujian Huang, Ming Liao

Summary: In recent years, there has been an increase in the occurrence of fowl adenovirus 2 (FAdV-2) in China, posing a significant threat to the poultry industry. This study investigated the epidemiology, phylogenetic relationship, genomic characteristics, and pathogenicity of FAdV-2. The results showed that FAdV-2 was the most commonly detected serotype among various FAdV serotypes. Genetic analysis revealed that these FAdV-2 strains formed a distinct branch within the FAdV-D group and had a high nucleotide similarity with reference strains. Recombination analysis identified recombination events between FAdV-2 and FAdV-11 in some strains. Pathogenicity experiments demonstrated that a recombinant FAdV-2 strain caused a high mortality rate and more severe disease in chickens. These findings contribute to our understanding of FAdV-2 and provide a basis for vaccine development.

POULTRY SCIENCE (2024)

Article Agriculture, Dairy & Animal Science

Effect of thermal manipulation on embryonic development, hatching process, and chick quality under heat-stress conditions

Ebtsam Iraqi, Ali Abdel Hady, Nadia Elsayed, Hanaa Khalil, Amina El-Saadany, Karim El-Sabrout

Summary: Thermal manipulation during egg incubation, particularly at 12 to 18 days, has positive effects on embryonic development, hatching characteristics, chick quality, as well as posthatch thermotolerance and performance.

POULTRY SCIENCE (2024)

Article Agriculture, Dairy & Animal Science

Curcumin improves the egg quality, antioxidant activity, and intestinal microbiota of quails during the late laying period

Yong Liu, Mingxin Song, He Bai, Chunhua Wang, Fei Wang, Qi Yuan

Summary: Dietary curcumin supplementation can significantly improve egg quality of quails in the late laying period, primarily by improving lipid metabolism and selectively regulating the intestinal microbial community.

POULTRY SCIENCE (2024)

Article Agriculture, Dairy & Animal Science

Molecular characterization and immune protective efficacy of 3 Eimeria tenella antigens

Lei Zhang, Zhixuan Song, Peiyao Li, Xingju Song, Xinming Tang, Dandan Hu

Summary: This study evaluated the vaccine potential of recombinant proteins for avian coccidiosis caused by Eimeria. The results showed that the rEten5-B protein can trigger immune protection against E. tenella and may be a potential and effective subunit vaccine for the control of coccidiosis in poultry.

POULTRY SCIENCE (2024)

Article Agriculture, Dairy & Animal Science

Graded levels of Eimeria infection modulated gut physiology and temporarily ceased the egg production of laying hens at peak production

Milan Kumar Sharma, Amit Kumar Singh, Doyun Goo, Venkata Sesha Reddy Choppa, Hanseo Ko, Hanyi Shi, Woo Kyun Kim

Summary: The study investigates the effect of Eimeria infection on gastrointestinal physiology, growth performance, and egg production of Hy-Line W-36 laying hens during peak production. Results show that Eimeria infection negatively affects body weight, feed intake, immune response, and nutrient transporter gene expression. Egg production temporarily ceases in hens infected with high and medium-high dosages of Eimeria.

POULTRY SCIENCE (2024)

Article Agriculture, Dairy & Animal Science

Effect of different energy, protein levels and their interaction on productive performance, egg quality, digestibility coefficient of laying Japanese quails

Elwy A. Ashour, Mahmoud Kamal, Hayman A. A. Altaie, Ayman A. Swelum, Gamaleldin M. Suliman, Guillermo Tellez-Isaias, Mohamed E. Abd El-Hack

Summary: This study evaluated the effects of CP and ME on the performance and nutritional value of Japanese quail lay chicken. The results showed that protein and energy levels significantly influenced all productive outcomes except feed conversion ratio. The combination of dietary energy and protein levels had a substantial effect on all egg quality trials evaluated. It is recommended to feed layer Japanese quail between the ages of 8 and 20 weeks during the summer with a dietary energy content of 2,900 kcal ME/kg and 20% CP.

POULTRY SCIENCE (2024)

Article Agriculture, Dairy & Animal Science

Tracking individual broilers on video in terms of time and distance

J. E. Doornweerd, R. F. Veerkamp, B. de Klerk, M. van der Sluis, A. C. Bouwman, E. D. Ellen, G. Kootstra

Summary: Tracking group-housed individual broilers using video can provide valuable information on their health, welfare, and performance. This study conducted a comprehensive analysis on broiler tracking on video and potential tracking errors, highlighting the potential and challenges of phenotyping broiler locomotion. The results emphasized the importance of addressing tracking errors, potential algorithm improvements, and the need for an external animal identification system for efficient locomotion phenotyping.

POULTRY SCIENCE (2024)

Article Agriculture, Dairy & Animal Science

Identification of genes related to growth and amino acid metabolism from the transcriptome profile of the liver of growing laying hens

Jiayu Wu, Yanan Wang, Yu An, Changyu Tian, Lingfeng Wang, Zuhong Liu, Desheng Qi

Summary: This study compared the gene expression differences in liver tissues of laying hens at different ages using RNA sequencing, and found that the transport and metabolism of amino acids changed during the growing period, which influenced the growth and development of the hens.

POULTRY SCIENCE (2024)

Article Agriculture, Dairy & Animal Science

Research Note: Irritating flashing light or poultry-friendly lighting-are flicker frequencies of LED luminaires a potential stress factor in the husbandry of male fattening turkeys?

J. Raabe, G. Raveendran, W. Otten, K. Homeyer, T. Bartels

Summary: This study investigated the effects of different flicker frequencies on the behavior, performance, and stress response in male turkeys. The results showed that flicker frequencies of 165 Hz or higher had no detrimental effect on growth performance, injurious pecking, or endocrine stress response in the turkeys.

POULTRY SCIENCE (2024)

Article Agriculture, Dairy & Animal Science

Transcriptome analysis of ovarian tissues highlights genes controlling energy homeostasis and oxidative stress as potential drivers of heterosis for egg number and clutch size in crossbred laying hens

Adamu Mani Isa, Yanyan Sun, Yuanmei Wang, Yunlei Li, Jingwei Yuan, Aixin Ni, Hui Ma, Lei Shi, Hailai Hagos Tesfay, Yunhe Zong, Panlin Wang, Pingzhuang Ge, Jilan Chen

Summary: This study sequenced mRNAs and lncRNAs in the ovary stroma of specific chicken breeds and their reciprocal crossbreds to understand the molecular mechanism of heterosis for egg production. Results showed that genes with nonadditive expression were related to follicle growth and atresia as well as oxidative stress in the crossbred hens.

POULTRY SCIENCE (2024)

Article Agriculture, Dairy & Animal Science

Refine localizations of functional variants affecting eggshell color of Lueyang black-boned chicken in the SLCO1B3

Zhepeng Wang, Qiu Chen, Yiwei Wang, Yulu Wang, Ruifang Liu

Summary: The study investigates the functional variants associated with chicken eggshell color in the SLCO1B3 gene by measuring the eggshell color of Lueyang black-boned chickens and analyzing the genetic data. It identifies 15 variants in SLCO1B3 that are significantly associated with eggshell color. However, the functional analysis shows that one specific variant, 1B3_SNP108, does not have a significant effect on promoter activity. This study highlights the importance of SLCO1B3 and its variants in breeding eggshell color.

POULTRY SCIENCE (2024)

Article Agriculture, Dairy & Animal Science

Spatial distribution, movement, body damage, and feather condition of laying hens in a multi-tier system

P. Yin, Q. Tong, B. M. Li, W. C. Zheng, Y. Wang, H. Q. Peng, X. L. Xue, S. Q. Wei

Summary: This study investigated the welfare and health of laying hens in a multitier system. The results showed that the spatial distribution of hens changed with increasing age, and lower-ranking hens preferred to stay in lower tiers to avoid competition but still had access to resources. This improved the welfare and health of the hens near the end of the laying cycle.

POULTRY SCIENCE (2024)

Article Agriculture, Dairy & Animal Science

Research Note: Factors influencing highly pathogenic avian influenza preventive behavior among live poultry market vendors

Wenwen Liang, Siqiong Jie, Yiqin Wang, Xiaowei Wen, Yanling Xiong, Xiaoxi Lin, Zhengrong Lv

Summary: This study examined the effect of risk perceptions on preventive behavior among vendors in the live poultry wholesale market and the live poultry retail market in Guangdong Province using the health belief model and structural equation modeling. The results showed that perceived severity and perceived benefits positively influenced vendors' self-efficacy in the wholesale market, while perceived barriers negatively affected self-efficacy in both the wholesale and retail markets. Moreover, cues to action mediated the relationship between perceived severity, perceived benefits, and self-efficacy, and also mediated the effect of perceived susceptibility among wholesale market vendors.

POULTRY SCIENCE (2024)

Article Agriculture, Dairy & Animal Science

In ovo feeding of probiotic lactobacilli differentially alters expression of genes involved in the development and immunological maturation of bursa of Fabricius in pre-hatched chicks

Shreeya Sharma, Raveendra R. Kulkarni, Shayan Sharif, Hosni Hassan, Mohammadali Alizadeh, Scott Pratt, Khaled Abdelaziz

Summary: The study investigates the impact of exposing chick embryos to antigens via in ovo delivery of poultry-specific lactobacilli on the expression of genes associated with early bursal development and maturation. Results indicate that the supplementation of poultry-specific lactobacilli to chick embryos can accelerate the development and immunological maturation of the bursa of Fabricius.

POULTRY SCIENCE (2024)