Ectopic Corticotropin-Producing Neuroendocrine Tumor of the Pancreas Treated With Lu-177 DOTATATE Induction and Maintenance Peptide Receptor Radionuclide Therapy

A 57-year-old woman diagnosed with ectopic Cushing syndrome was found to have a In-111-octreotide-avid corticotropin-producing pancreatic neuroendocrine tumor with liver metastases. She was treated with 4 induction and 4 maintenance cycles of Lu-177-DOTATATE, which normalized her serum corticotropin levels and dramatically reduced the size of the pancreatic primary and liver metastases.