Article
Oncology
Wenzhi Jia, Qianyun Wu, Xiaofeng Yu, Mengqin Shen, Ruixue Zhang, Jiajin Li, Li Zhao, Gang Huang, Jianjun Liu
Summary: The glycolytic enzyme fructose 1,6-bisphosphate aldolase B (ALDOB) is inversely correlated with F-18-fluorodeoxyglucose (F-18-FDG) uptake in hepatocellular carcinoma (HCC) patients. The combination of ALDOB expression and F-18-FDG PET/CT data may provide additional prognostic information for HCC patients.
FRONTIERS IN ONCOLOGY
(2022)
Article
Oncology
Aida Sabate-Llobera, Judit Mestres-Marti, Gabriel Reynes-Llompart, Laura Llado, Kristel Mils, Teresa Serrano, Montserrat Cortes-Romera, Esther Bertran, Isabel Fabregat, Emilio Ramos
Summary: Functional imaging techniques such as PET/CT with FDG have been studied to identify aggressive features in HCC. Increased FDG uptake in HCC lesions may predict certain aggressive factors. A baseline PET/CT with FDG can help identify patients with histological factors of a poor prognosis preoperatively.
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Xilan Yao, Xiaohong Ou
Summary: A 50-year-old man presented with right chest pain and increased parathyroid hormone levels after parathyroidectomy. PET/CT scans revealed an osteolytic lesion on the right sixth rib, which was confirmed to be a brown tumor upon subsequent biopsy.
CLINICAL NUCLEAR MEDICINE
(2022)
Article
Oncology
Hao Wang, Wenwei Zhu, Shuhua Ren, Yanyan Kong, Qi Huang, Jun Zhao, Yihui Guan, Huliang Jia, Jinhong Chen, Lu Lu, Fang Xie, Lunxiu Qin
Summary: Ga-68-FAPI-04 PET/CT is more sensitive than F-18-FDG PET/CT in detecting HCC lesions, and Ga-68-FAPI-04 uptake is mainly correlated with tumor size.
FRONTIERS IN ONCOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Luca Filippi, Oreste Bagni, Ermanno Notarianni, Adelchi Saltarelli, Cesare Ambrogi, Orazio Schillaci
Summary: The study aimed to assess the role of PET/CT in hepatocellular carcinoma (HCC) patients and found that PET/CT had a significant impact on clinical management and patients' overall survival.
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Ting Yang, Min-Hong Zou, Qiong Zou, Ju Jiao, Yong Zhang
Summary: In this article, we report a case of sarcomatoid hepatocellular carcinoma that achieved complete remission with PD-1 treatment, providing some assistance for the diagnosis and treatment of this rare subtype.
CLINICAL NUCLEAR MEDICINE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Chunjuan Jiang, Liwei Zhao, Bowen Xin, Guang Ma, Xiuying Wang, Shaoli Song
Summary: This study explores the contribution of F-18-FDG PET/CT radiomic features for the preoperative prediction of HCC and ICC classification and MVI. The results show that the prediction model has high accuracy and sensitivity in predicting HCC and ICC classification, and PET features play a dominant role in the predictive power of the model. This prediction model provides a non-invasive biomarker for an earlier indication and comprehensive quantification of primary liver cancers.
QUANTITATIVE IMAGING IN MEDICINE AND SURGERY
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Sang Hyun Hwang, Hye-Suk Hong, Dongwoo Kim, Gyoung Min Kim, Hye Won Lee, Misu Lee, Do Young Kim, Mi-Ae Park, Mijin Yun
Summary: This study evaluated the prognostic value of metabolic parameters on F-18-FDG PET/CT and tumor dose (TD) on post-treatment Y-90 PET/CT in HCC patients undergoing Y-90 transarterial radioembolization (TARE). The results showed that TLG is a better prognostic factor for OS than TD in these patients.
CLINICAL NUCLEAR MEDICINE
(2022)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Jin Qi, Elizabeth Kurian, Orhan K. oez
Summary: Hibernomas are rare benign tumors originating from fetal brown adipose tissue. They can occur in various parts of the body, with thigh, shoulder, back, and neck being the most common locations, and are rarely found in the abdominal cavity, retroperitoneum, breast, bones, scrotum, and perirectum. We present a case of a 58-year-old woman with a mediastinal mass, who was incidentally found to have an FDG-avid fat-containing lesion in the omentum abutting the stomach.
CLINICAL NUCLEAR MEDICINE
(2023)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Saurav Jha, Angel Hemrom, Shamim Ahmed Shamim, Adarsh Barwad, Atul Batra
Summary: Renal cell carcinoma (RCC) accounts for 2% of global cancers and deaths. CT and MRI are commonly used for RCC evaluation, while PET/CT is used for assessing metastatic disease. A case study shows that Ga-68-PSMA may be a potential tracer for evaluating RCC, as it demonstrated better visibility of liver lesions compared to F-18-FDG.
CLINICAL NUCLEAR MEDICINE
(2023)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Jinxin Zhang, Weidong Gong, Wenwen Zhang, Chunyin Zhang, Guoxu Zhang
Summary: Adrenal sarcomatoid carcinoma is an extremely rare disease. A 53-year-old man was admitted to our hospital due to upper right abdominal pain for 1 month. Abdominal CT and PET/CT showed a huge malignancy in the right adrenal gland. Finally, the diagnosis of adrenal sarcomatoid carcinoma was confirmed by postoperative pathology.
CLINICAL NUCLEAR MEDICINE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Yiqiu Zhang, Yun Dong, Wenjun Yu, Shuguang Chen, Haojun Yu, Beilei Li, Hongcheng Shi
Summary: This study aimed to investigate the diagnostic value of early dynamic F-18-FDG PET/CT combined with conventional whole-body F-18-FDG PET/CT in hepatocellular carcinoma (HCC), as well as the difference of early dynamic blood flow parameters and maximum standardized uptake value (SUVmax) in HCC patients with/without liver cirrhosis or microvascular invasion (MVI). The results showed that the combined application of early dynamic and whole-body PET/CT significantly increased the detection rate of moderately differentiated and poorly differentiated HCCs; HPI was significantly higher in HCCs in patients with liver cirrhosis compared to those without liver cirrhosis; TTP was significantly shorter in HCCs with MVI compared to those without MVI.
ABDOMINAL RADIOLOGY
(2023)
Article
Radiology, Nuclear Medicine & Medical Imaging
Keunyoung Kim, Seong-Jang Kim
Summary: This meta-analysis evaluated the diagnostic accuracies of preoperative F-18 FDG PET or PET/CT for prediction of MVI in HCC patients, showing low sensitivity and moderate specificity. It suggests cautious application and interpretation of F-18 FDG PET or PET/CT for preoperative prediction of MVI in HCC patients.
Article
Radiology, Nuclear Medicine & Medical Imaging
Sung Ryul Shim, Seong-Jang Kim
Summary: This study evaluated the diagnostic accuracies of F-18-FDG PET or PET/CT for Merkel cell carcinoma (MCC) through a systematic review and meta-analysis. The results showed that F-18-FDG PET/CT had excellent performance in diagnosing MCC and could be useful for exclusion and confirmation of the disease. Further large multicenter studies are needed to validate its diagnostic accuracy.
CLINICAL NUCLEAR MEDICINE
(2022)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Caner Civan, Emine Goknur Isik, Seyfullah Karadogan, Yasemin Sanli, Serkan Kuyumcu
Summary: This article presents a case of a 62-year-old male with progressive left-sided papillary renal cell carcinoma. Ga-68-FAPI-04 and F-18-FDG PET/CT imaging revealed variable FAP expression in all metastatic lesions, including lymph nodes, bone, and thyroid. This case highlights the potential of FAP-targeted imaging for diagnostic and theranostic use in papillary renal cell carcinoma.
CLINICAL NUCLEAR MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Quentin Brana, Frederique Thibault, Maxime Courtehoux, Gilles Metrard, Maria Joao Ribeiro, Denis Angoulvant, Matthieu Bailly
Summary: This study compared the effects of dipyridamole and regadenoson on inducing hyperemia and found that they were equally effective in comparable patients.
JOURNAL OF NUCLEAR CARDIOLOGY
(2022)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Anne-Claire Dupont, Fanny Borrelly, Thierry Lecomte, Serge Maia, Maria-Joao Santiago Ribeiro
Summary: In this case, Ga-68-DOTATOC PET/CT imaging revealed abnormal biodistribution of the tracer with vascular binding and very low fixation on known lesions, possibly due to a high intake of turmeric inhibiting hepatic uptake process.
CLINICAL NUCLEAR MEDICINE
(2021)
Review
Neurosciences
Dominique Gouilly, Laure Saint-Aubert, Maria-Joao Ribeiro, Anne-Sophie Salabert, Clovis Tauber, Patrice Peran, Nicolas Arlicot, Jeremie Pariente, Pierre Payoux
Summary: This review provides an update on the results from 2018 and advances the characterization of TSPO imaging in Alzheimer's disease (AD) by re-examining TSPO function and expression. Although the biological basis of the TSPO PET signal is clearly related to microglia and astrocytes in AD, the exact process remains uncertain and may not be directly associated with neuroinflammation. Further studies are needed to explore the cellular significance underlying variations in the PET signal in AD.
EUROPEAN JOURNAL OF NEUROSCIENCE
(2022)
Article
Neurosciences
Quentin Gallet, Vincent Bouteloup, Maxime Locatelli, Marie-Odile Habert, Marie Chupin, Julien Delrieu, Thibaud Lebouvier, Gabriel Robert, Renaud David, Samuel Bulteau, Anna-Chloe Balageas, Alexandre Surget, Catherine Belzung, Nicolas Arlicot, Maria-Joao Ribeiro, Laurent Barantin, Frederic Andersson, Jean-Philippe Cottier, Valerie Gissot, Wissam El-Hage, Vincent Camus, Benedicte Gohier, Thomas Desmidt
Summary: Recent evidence suggests a connection between BZDs use and lower brain amyloid load, with potential effects on hippocampal volume and symptoms of depression, anxiety, and apathy. Additional research is needed to confirm the causal relationship and explore potential therapeutic targets for Alzheimer's disease.
NEUROPSYCHOPHARMACOLOGY
(2022)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Thibaut Carsuzaa, Frederique Thibault, Matthieu Bailly
Summary: The use of a 3D-ring CZT system seems to be effective in evaluating and monitoring left cardiac function, with potential benefits of dose reduction and quicker acquisitions.
CLINICAL NUCLEAR MEDICINE
(2022)
Article
Medicine, General & Internal
Helene Besse, Matthieu Bailly
Summary: Lymphoscintigraphy is considered the gold standard imaging modality for diagnosing lymphedema, but protocol variability and poor image resolution can make interpretation challenging. This case report demonstrates the use of SPECT/CT in diagnosing lymphatic dysfunction in a patient with lower limb edema, supporting the development of this technique in clinical practice.
FRONTIERS IN MEDICINE
(2022)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Gilles Metrard, Helene Besse, Aurelien Callaud, Frederique Thibault, Matthieu Bailly
Summary: This case illustrates the possibility of increased muscular F-18-FDG uptake without myositis in patients with statin-associated muscle symptoms. Discontinuation of statin treatment for one week can reduce muscular uptake.
CLINICAL NUCLEAR MEDICINE
(2022)
Article
Medicine, General & Internal
Bastien Vancon, Arnaud Bisson, Maxime Courtehoux, Anne Bernard, Matthieu Bailly
Summary: This study aims to confirm the presence of coronary microvascular dysfunction and evaluate the effect of Tafamidis on microvascular function after 24 months of treatment. It is a multicentric, prospective, observational cohort study involving adult patients with confirmed ATTR cardiomyopathy. The results of this study will provide insights into the therapeutic effect of Tafamidis in patients with cardiac amyloidosis.
FRONTIERS IN MEDICINE
(2022)
Article
Radiology, Nuclear Medicine & Medical Imaging
Matthieu Bailly, Gilles Le Rouzic, Gilles Metrard
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2023)
Editorial Material
Radiology, Nuclear Medicine & Medical Imaging
Matthieu Bailly, Aurelien Callaud, Gilles Metrard
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2023)
Meeting Abstract
Radiology, Nuclear Medicine & Medical Imaging
Johnny Vercouillie, Anne-Claire Dupont, Nicolas Arlicot, Valerie Gissot, Gabrielle Chicheri, Laurent Barantin, Frederique Bonnet-Brilhault, Maria Joao Ribeiro
NUCLEAR MEDICINE AND BIOLOGY
(2022)
Meeting Abstract
Radiology, Nuclear Medicine & Medical Imaging
M. Bailly, G. Le Rouzic, G. Metrard
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2021)
Meeting Abstract
Radiology, Nuclear Medicine & Medical Imaging
T. Carsuzaa, F. Thibault, M. Bailly
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2021)
Meeting Abstract
Radiology, Nuclear Medicine & Medical Imaging
M. Bailly, F. Thibault, G. Metrard, M. Courtehoux, D. Angoulvant, M. Ribeiro
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING
(2021)