The Role of the Curcumin for Inducing Apoptosis in Acute Lymphoblastic Leukemia Cells: A Systematic Review

CNB-001, a synthetic pyrazole derivative of curcumin, suppresses lipopolysaccharide-induced nitric oxide production through the inhibition of NF-κB and p38 MAPK pathways in microglia

(2018) Tatsuhiro Akaishi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Inhibition of curcumin on influenza A virus infection and influenzal pneumonia via oxidative stress, TLR2/4, p38/JNK MAPK and NF-κB pathways

(2018) Jianping Dai et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Antitumor activity of curcumin by modulation of apoptosis and autophagy in human lung cancer A549 cells through inhibiting PI3K/Akt/mTOR pathway

(2018) Furong Liu et al.   ONCOLOGY REPORTS

Curcumin ameliorates the in vitro efficacy of carfilzomib in human multiple myeloma U266 cells targeting p53 and NF-κB pathways

(2018) Alessandro Allegra et al.   TOXICOLOGY IN VITRO

(S021) A Phase 2 Randomized Double Blinded Study Evaluating the Efficacy of Curcumin With Pre-Operative Chemoradiation for Rectal Cancer

(2017) Jillian R. Gunther et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Injectable dopamine-modified poly(α,β-aspartic acid) nanocomposite hydrogel as bioadhesive drug delivery system

(2017) Chu Gong et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

HDAC1,2 inhibition and doxorubicin impair Mre11-dependent DNA repair and DISC to override BCR-ABL1-driven DSB repair in Philadelphia chromosome-positive B-cell precursor acute lymphoblastic leukemia

(2017) S Tharkar-Promod et al.   LEUKEMIA

Silencing of Y-box binding protein-1 by RNA interference inhibits proliferation, invasion, and metastasis, and enhances sensitivity to cisplatin through NF-κB signaling pathway in human neuroblastoma SH-SY5Y cells

(2017) Hong Wang et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Curcumin nanomicelle improves semen parameters, oxidative stress, inflammatory biomarkers, and reproductive hormones in infertile men: A randomized clinical trial

(2017) Fatemeh Alizadeh et al.   PHYTOTHERAPY RESEARCH

Curcumin Suppresses Lung Cancer Stem Cells via Inhibiting Wnt/β-catenin and Sonic Hedgehog Pathways

(2017) Jian-Yun Zhu et al.   PHYTOTHERAPY RESEARCH

Curcumin Ameliorates Cisplatin-Induced Nephrotoxicity and Potentiates Its Anticancer Activity in SD Rats: Potential Role of Curcumin in Breast Cancer Chemotherapy

(2017) Parveen Kumar et al.   Frontiers in Pharmacology

Selective Targeting of Cancer Cells by Oxidative Vulnerabilities with Novel Curcumin Analogs

(2017) Christopher Pignanelli et al.   Scientific Reports

Curcumin as a multifaceted compound against human papilloma virus infection and cervical cancers: A review of chemistry, cellular, molecular, and preclinical features

(2016) Manouchehr Teymouri et al.   BIOFACTORS

Curcumin induces apoptosis by inhibiting sarco/endoplasmic reticulum Ca2+ ATPase activity in ovarian cancer cells

(2016) Jeong-ah Seo et al.   CANCER LETTERS

Clinical updates in adult acute lymphoblastic leukemia

(2016) Omar Al Ustwani et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

3,3′-OH curcumin causes apoptosis in HepG2 cells through ROS-mediated pathway

(2016) Guo-Yun Liu et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Growth inhibitory and proapoptotic effects of l -asparaginase from Fusarium culmorum ASP-87 on human leukemia cells (Jurkat)

(2016) Anil K. Meghavarnam et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Curcumin: A new candidate for melanoma therapy?

(2016) Hamed Mirzaei et al.   INTERNATIONAL JOURNAL OF CANCER

The Curcumin Analog C-150, Influencing NF-κB, UPR and Akt/Notch Pathways Has Potent Anticancer Activity In Vitro and In Vivo

(2016) László Hackler et al.   PLoS One

Curcumin potentiates the effect of chemotherapy against acute lymphoblastic leukemia cells via downregulation of NF-κB

(2016) Helia Judith Pimentel-Gutiérrez et al.   Oncology Letters

Curcumin Suppressed Activation of Dendritic Cells via JAK/STAT/SOCS Signal in Mice with Experimental Colitis

(2016) Hai-Mei Zhao et al.   Frontiers in Pharmacology

The role of JAK/STAT signalling in the pathogenesis, prognosis and treatment of solid tumours

(2015) S J Thomas et al.   BRITISH JOURNAL OF CANCER

Oncogene addiction: pathways of therapeutic response, resistance, and road maps toward a cure

(2015) R. Pagliarini et al.   EMBO REPORTS

Curcumin potentiates the anti-leukemia effects of imatinib by downregulation of the AKT/mTOR pathway and BCR/ABL gene expression in Ph+ acute lymphoblastic leukemia

(2015) Yong Guo et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The Multifaceted Role of Curcumin in Cancer Prevention and Treatment

(2015) Muthu Shanmugam et al.   MOLECULES

Curcumin inhibits in vitro and in vivo chronic myelogenous leukemia cells growth: a possible role for exosomal disposal of miR-21

(2015) Simona Taverna et al.   Oncotarget

JAK Kinase Inhibition Abrogates STAT3 Activation and Head and Neck Squamous Cell Carcinoma Tumor Growth

(2015) Malabika Sen et al.   NEOPLASIA

Curcumin Inhibits the AKT/NF-κB Signaling via CpG Demethylation of the Promoter and Restoration of NEP in the N2a Cell Line

(2014) Yushuang Deng et al.   AAPS Journal

Curcumin induces apoptosis of multidrug-resistant human leukemia HL60 cells by complex pathways leading to ceramide accumulation

(2014) Abo Bakr Abdel Shakor et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Mechanisms of Jak/STAT Signaling in Immunity and Disease

(2014) Alejandro V. Villarino et al.   JOURNAL OF IMMUNOLOGY

Inhibition of JAK-STAT signaling stimulates adult satellite cell function

(2014) Feodor D Price et al.   NATURE MEDICINE

Molecular mechanisms of curcumin action: Signal transduction

(2013) Adeeb Shehzad et al.   BIOFACTORS

Importance of Detecting Multidrug Resistance Proteins in Acute Leukemia Prognosis and Therapy

(2013) Ana Carolina Rabello de Moraes et al.   JOURNAL OF CLINICAL LABORATORY ANALYSIS

Biology of Childhood Acute Lymphoblastic Leukemia

(2013) Luca Lo Nigro   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

Curcumin induces osteosarcoma MG63 cells apoptosis via ROS/Cyto-C/Caspase-3 pathway

(2013) Zhengqi Chang et al.   TUMOR BIOLOGY

Recent advances in apoptosis, mitochondria and drug resistance in cancer cells

(2011) Inthrani R. Indran et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Curcumin potentiates antitumor activity ofl-asparaginase via inhibition of the AKT signaling pathway in acute lymphoblastic leukemia

(2011) Hua Wang et al.   LEUKEMIA & LYMPHOMA

Activation of Akt is associated with poor prognosis and chemotherapeutic resistance in pediatric B-precursor acute lymphoblastic leukemia

(2011) Naoto Morishita et al.   PEDIATRIC BLOOD & CANCER

Frequent and Simultaneous Epigenetic Inactivation of TP53 Pathway Genes in Acute Lymphoblastic Leukemia

(2011) Amaia Vilas–Zornoza et al.   PLoS One

A phase I/II study of gemcitabine-based chemotherapy plus curcumin for patients with gemcitabine-resistant pancreatic cancer

(2010) Masashi Kanai et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Curcumin―The Paradigm of a Multi-Target Natural Compound with Applications in Cancer Prevention and Treatment

(2010) Marie-Hélène Teiten et al.   Toxins

Curcumin Suppresses the Paclitaxel-Induced Nuclear Factor-κB in Breast Cancer Cells and Potentiates the Growth Inhibitory Effect of Paclitaxel in a Breast Cancer Nude Mice Model

(2009) Hee Joon Kang et al.   Breast Journal

Curcumin suppresses p38 mitogen-activated protein kinase activation, reduces IL-1β and matrix metalloproteinase-3 and enhances IL-10 in the mucosa of children and adults with inflammatory bowel disease

(2009) Jenny Epstein et al.   BRITISH JOURNAL OF NUTRITION

Apoptosis and non-apoptotic deaths in cancer development and treatment response

(2008) Elza C. de Bruin et al.   CANCER TREATMENT REVIEWS

Reactive oxygen species and nitric oxide regulate mitochondria-dependent apoptosis and autophagy in evodiamine-treated human cervix carcinoma HeLa cells

(2008) Jia Yang et al.   FREE RADICAL RESEARCH

Curcumin inhibits proliferation and induces apoptosis of leukemic cells expressing wild-type or T315I-BCR-ABL and prolongs survival of mice with acute lymphoblastic leukemia

(2008) Basem M. William et al.   Hematology