Deschloroclozapine, a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys
出版年份 2020 全文链接
标题
Deschloroclozapine, a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys
作者
关键词
-
出版物
NATURE NEUROSCIENCE
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2020-07-07
DOI
10.1038/s41593-020-0661-3
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- TRUPATH, an open-source biosensor platform for interrogating the GPCR transducerome
- (2020) Reid H. J. Olsen et al. Nature Chemical Biology
- Acoustically targeted chemogenetics for the non-invasive control of neural circuits
- (2018) Jerzy O. Szablowski et al. Nature Biomedical Engineering
- Behavioral Effect of Chemogenetic Inhibition Is Directly Related to Receptor Transduction Levels in Rhesus Monkeys
- (2018) Nicholas A. Upright et al. JOURNAL OF NEUROSCIENCE
- The DREADD agonist clozapine N-oxide (CNO) is reverse-metabolized to clozapine and produces clozapine-like interoceptive stimulus effects in rats and mice
- (2018) Daniel F. Manvich et al. Scientific Reports
- A Comparative Study of the Pharmacokinetics of Clozapine N-Oxide and Clozapine N-Oxide Hydrochloride Salt in Rhesus Macaques
- (2018) Daicia C. Allen et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Chemogenetics revealed: DREADD occupancy and activation via converted clozapine
- (2017) Juan L. Gomez et al. SCIENCE
- Multimodal Imaging for DREADD-Expressing Neurons in Living Brain and Their Application to Implantation of iPSC-Derived Neural Progenitors
- (2016) Bin Ji et al. JOURNAL OF NEUROSCIENCE
- The Rhesus Monkey Connectome Predicts Disrupted Functional Networks Resulting from Pharmacogenetic Inactivation of the Amygdala
- (2016) David S. Grayson et al. NEURON
- DREADDs for Neuroscientists
- (2016) Bryan L. Roth NEURON
- PET imaging-guided chemogenetic silencing reveals a critical role of primate rostromedial caudate in reward evaluation
- (2016) Yuji Nagai et al. Nature Communications
- The First Structure–Activity Relationship Studies for Designer Receptors Exclusively Activated by Designer Drugs
- (2015) Xin Chen et al. ACS Chemical Neuroscience
- Chemogenetic disconnection of monkey orbitofrontal and rhinal cortex reversibly disrupts reward value
- (2015) Mark A G Eldridge et al. NATURE NEUROSCIENCE
- PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome
- (2015) Wesley K Kroeze et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- A New DREADD Facilitates the Multiplexed Chemogenetic Interrogation of Behavior
- (2015) Eyal Vardy et al. NEURON
- PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome
- (2015) Wesley K Kroeze et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Changes in Cortical Microvasculature during Misery Perfusion Measured by Two-Photon Laser Scanning Microscopy
- (2014) Yosuke Tajima et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Chemogenetic Synaptic Silencing of Neural Circuits Localizes a Hypothalamus→Midbrain Pathway for Feeding Behavior
- (2014) Tevye J. Stachniak et al. NEURON
- Chemical–genetic attenuation of focal neocortical seizures
- (2014) Dennis Kätzel et al. Nature Communications
- Whole-brain circuit dissection in free-moving animals reveals cell-specific mesocorticolimbic networks
- (2013) Michael Michaelides et al. JOURNAL OF CLINICAL INVESTIGATION
- Pharmacosynthetics: Reimagining the pharmacogenetic approach
- (2012) Martilias S. Farrell et al. BRAIN RESEARCH
- The origin of extracellular fields and currents — EEG, ECoG, LFP and spikes
- (2012) György Buzsáki et al. NATURE REVIEWS NEUROSCIENCE
- Factors Influencing the Use and Interpretation of Animal Models in the Development of Parenteral Drug Delivery Systems
- (2011) Marilyn N. Martinez AAPS Journal
- Cholinergic modulation of a specific memory function of prefrontal cortex
- (2011) Paula L Croxson et al. NATURE NEUROSCIENCE
- Reproducibility and variance of a stimulation-induced hemodynamic response in barrel cortex of awake behaving mice
- (2010) Hiroyuki Takuwa et al. BRAIN RESEARCH
- Measurement of Unbound Drug Exposure in Brain: Modeling of pH Partitioning Explains Diverging Results between the Brain Slice and Brain Homogenate Methods
- (2010) M. Friden et al. DRUG METABOLISM AND DISPOSITION
- Remote Control of Neuronal Activity in Transgenic Mice Expressing Evolved G Protein-Coupled Receptors
- (2009) Georgia M. Alexander et al. NEURON
- Measuring and Modeling the Interaction Among Reward Size, Delay to Reward, and Satiation Level on Motivation in Monkeys
- (2008) Takafumi Minamimoto et al. JOURNAL OF NEUROPHYSIOLOGY
- A population-average MRI-based atlas collection of the rhesus macaque
- (2008) Donald G. McLaren et al. NEUROIMAGE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More