标题
Neuropilin-1 is a T cell memory checkpoint limiting long-term antitumor immunity
作者
关键词
-
出版物
NATURE IMMUNOLOGY
Volume -, Issue -, Pages -
出版商
Springer Science and Business Media LLC
发表日期
2020-07-14
DOI
10.1038/s41590-020-0733-2
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Intratumoral Tcf1+PD-1+CD8+ T Cells with Stem-like Properties Promote Tumor Control in Response to Vaccination and Checkpoint Blockade Immunotherapy
- (2019) Imran Siddiqui et al. IMMUNITY
- Subsets of exhausted CD8+ T cells differentially mediate tumor control and respond to checkpoint blockade
- (2019) Brian C. Miller et al. NATURE IMMUNOLOGY
- Epigenetic signature of PD-1+ TCF1+ CD8 T cells that act as resource cells during chronic viral infection and respond to PD-1 blockade
- (2019) Rohit R. Jadhav et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulation of antitumour CD8 T-cell immunity and checkpoint blockade immunotherapy by Neuropilin-1
- (2019) Marine Leclerc et al. Nature Communications
- c-Jun overexpression in CAR T cells induces exhaustion resistance
- (2019) Rachel C. Lynn et al. NATURE
- An intra-tumoral niche maintains and differentiates stem-like CD8 T cells
- (2019) Caroline S. Jansen et al. NATURE
- The function and dysfunction of memory CD8+ T cells in tumor immunity
- (2018) James L. Reading et al. IMMUNOLOGICAL REVIEWS
- Transcription Factor IRF4 Promotes CD8 + T Cell Exhaustion and Limits the Development of Memory-like T Cells during Chronic Infection
- (2017) Kevin Man et al. IMMUNITY
- Differential Requirements for Tcf1 Long Isoforms in CD8+and CD4+T Cell Responses to Acute Viral Infection
- (2017) Jodi A. Gullicksrud et al. JOURNAL OF IMMUNOLOGY
- Multifaceted Role of Neuropilins in the Immune System: Potential Targets for Immunotherapy
- (2017) Sohini Roy et al. Frontiers in Immunology
- T Cell Factor 1-Expressing Memory-like CD8 + T Cells Sustain the Immune Response to Chronic Viral Infections
- (2016) Daniel T. Utzschneider et al. IMMUNITY
- Defining CD8+ T cells that provide the proliferative burst after PD-1 therapy
- (2016) Se Jin Im et al. NATURE
- CXCR5+ follicular cytotoxic T cells control viral infection in B cell follicles
- (2016) Yew Ann Leong et al. NATURE IMMUNOLOGY
- The future of cancer treatment: immunomodulation, CARs and combination immunotherapy
- (2016) Danny N. Khalil et al. Nature Reviews Clinical Oncology
- The epigenetic landscape of T cell exhaustion
- (2016) D. R. Sen et al. SCIENCE
- Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade
- (2016) K. E. Pauken et al. SCIENCE
- The Transcription Factor NFAT Promotes Exhaustion of Activated CD8 + T Cells
- (2015) Gustavo J. Martinez et al. IMMUNITY
- mTOR Complex Signaling through the SEMA4A–Plexin B2 Axis Is Required for Optimal Activation and Differentiation of CD8+T Cells
- (2015) Daisuke Ito et al. JOURNAL OF IMMUNOLOGY
- limma powers differential expression analyses for RNA-sequencing and microarray studies
- (2015) Matthew E. Ritchie et al. NUCLEIC ACIDS RESEARCH
- Neuropilin-1 Expression Is Induced on Tolerant Self-Reactive CD8+ T Cells but Is Dispensable for the Tolerant Phenotype
- (2014) Stephanie R. Jackson et al. PLoS One
- Stability and function of regulatory T cells is maintained by a neuropilin-1–semaphorin-4a axis
- (2013) Greg M. Delgoffe et al. NATURE
- Smart-seq2 for sensitive full-length transcriptome profiling in single cells
- (2013) Simone Picelli et al. NATURE METHODS
- Network Analysis Reveals Centrally Connected Genes and Pathways Involved in CD8+ T Cell Exhaustion versus Memory
- (2012) Travis A. Doering et al. IMMUNITY
- Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer
- (2012) Suzanne L. Topalian et al. NEW ENGLAND JOURNAL OF MEDICINE
- Autoimmune melanocyte destruction is required for robust CD8+ memory T cell responses to mouse melanoma
- (2011) Katelyn T. Byrne et al. JOURNAL OF CLINICAL INVESTIGATION
- Repression of the DNA-binding inhibitor Id3 by Blimp-1 limits the formation of memory CD8+ T cells
- (2011) Yun Ji et al. NATURE IMMUNOLOGY
- The transcriptional regulators Id2 and Id3 control the formation of distinct memory CD8+ T cell subsets
- (2011) Cliff Y Yang et al. NATURE IMMUNOLOGY
- Local Induction of Immunosuppressive CD8+ T Cells in the Gut-Associated Lymphoid Tissues
- (2010) Diana Fleissner et al. PLoS One
- Metastatic tumour cells favour the generation of a tolerogenic milieu in tumour draining lymph node in patients with early cervical cancer
- (2009) Alessandra Battaglia et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Notch2 integrates signaling by the transcription factors RBP-J and CREB1 to promote T cell cytotoxicity
- (2008) Yoichi Maekawa et al. NATURE IMMUNOLOGY
- Neuropilin-1 expression identifies a subset of regulatory T cells in human lymph nodes that is modulated by preoperative chemoradiation therapy in cervical cancer
- (2007) Alessandra Battaglia et al. IMMUNOLOGY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started