Tissue-resident memory CD8+ T cells shape local and systemic secondary T cell responses

Developmental plasticity allows outside-in immune responses by resident memory T cells

(2020) Raissa Fonseca et al.   NATURE IMMUNOLOGY

Central memory CD8+ T cells become CD69+ tissue-residents during viral skin infection independent of CD62L-mediated lymph node surveillance

(2019) Jossef F. Osborn et al.   PLoS Pathogens

T Cells in Nonlymphoid Tissues Give Rise to Lymph-Node-Resident Memory T Cells

(2018) Lalit K. Beura et al.   IMMUNITY

Intravital mucosal imaging of CD8+ resident memory T cells shows tissue-autonomous recall responses that amplify secondary memory

(2018) Lalit K. Beura et al.   NATURE IMMUNOLOGY

Local proliferation maintains a stable pool of tissue-resident memory T cells after antiviral recall responses

(2018) Simone L. Park et al.   NATURE IMMUNOLOGY

Blimp-1 induces and Hobit maintains the cytotoxic mediator granzyme B in CD8 T cells

(2018) Natasja A.M. Kragten et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Repeated Antigen Exposure Extends the Durability of Influenza-Specific Lung-Resident Memory CD8+ T Cells and Heterosubtypic Immunity

(2018) Natalija Van Braeckel-Budimir et al.   Cell Reports

Armed and Ready: Transcriptional Regulation of Tissue-Resident Memory CD8 T Cells

(2018) Felix M. Behr et al.   Frontiers in Immunology

Enhanced anti-tumour immunity requires the interplay between resident and circulating memory CD8+ T cells

(2017) Michel Enamorado et al.   Nature Communications

The Chemokine Receptor CX3CR1 Defines Three Antigen-Experienced CD8 T Cell Subsets with Distinct Roles in Immune Surveillance and Homeostasis

(2016) Carmen Gerlach et al.   IMMUNITY

Liver-Resident Memory CD8 + T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection

(2016) Daniel Fernandez-Ruiz et al.   IMMUNITY

A molecular threshold for effector CD8+ T cell differentiation controlled by transcription factors Blimp-1 and T-bet

(2016) Annie Xin et al.   NATURE IMMUNOLOGY

Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes

(2016) L. K. Mackay et al.   SCIENCE

Quantifying Memory CD8 T Cells Reveals Regionalization of Immunosurveillance

(2015) Elizabeth M. Steinert et al.   CELL

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Functional classification of memory CD8+ T cells by CX3CR1 expression

(2015) Jan P. Böttcher et al.   Nature Communications

Oral Infection Drives a Distinct Population of Intestinal Resident Memory CD8+ T Cells with Enhanced Protective Function

(2014) Brian S. Sheridan et al.   IMMUNITY

Tissue-Resident Memory T Cells

(2014) Jason M. Schenkel et al.   IMMUNITY

Serial Transfer of Single-Cell-Derived Immunocompetence Reveals Stemness of CD8+ Central Memory T Cells

(2014) Patricia Graef et al.   IMMUNITY

Cutting Edge: Resident Memory CD8 T Cells Occupy Frontline Niches in Secondary Lymphoid Organs

(2014) J. M. Schenkel et al.   JOURNAL OF IMMUNOLOGY

Resident memory CD8 T cells trigger protective innate and adaptive immune responses

(2014) J. M. Schenkel et al.   SCIENCE

Skin-resident memory CD8+ T cells trigger a state of tissue-wide pathogen alert

(2014) S. Ariotti et al.   SCIENCE

Transformation of intestinal stem cells into gastric stem cells on loss of transcription factor Cdx2

(2014) Salvatore Simmini et al.   Nature Communications

Preexisting High Frequencies of Memory CD8+ T Cells Favor Rapid Memory Differentiation and Preservation of Proliferative Potential upon Boosting

(2013) Kathryn A. Fraser et al.   IMMUNITY

Effector-like CD8+ T Cells in the Memory Population Mediate Potent Protective Immunity

(2013) Janelle A. Olson et al.   IMMUNITY

Transcriptional downregulation of S1pr1 is required for the establishment of resident memory CD8+ T cells

(2013) Cara N Skon et al.   NATURE IMMUNOLOGY

Sensing and alarm function of resident memory CD8+ T cells

(2013) Jason M Schenkel et al.   NATURE IMMUNOLOGY

The developmental pathway for CD103+CD8+ tissue-resident memory T cells of skin

(2013) Laura K Mackay et al.   NATURE IMMUNOLOGY

Memory T Cell Subsets, Migration Patterns, and Tissue Residence

(2012) Scott N. Mueller et al.   Annual Review of Immunology

Mouse Hobit is a homolog of the transcriptional repressor Blimp-1 that regulates NKT cell effector differentiation

(2012) Klaas P J M van Gisbergen et al.   NATURE IMMUNOLOGY

CEL-Seq: Single-Cell RNA-Seq by Multiplexed Linear Amplification

(2012) Tamar Hashimshony et al.   Cell Reports

Protective Capacity of Memory CD8+ T Cells Is Dictated by Antigen Exposure History and Nature of the Infection

(2011) Jeffrey C. Nolz et al.   IMMUNITY

Fast and accurate long-read alignment with Burrows–Wheeler transform

(2010) Heng Li et al.   BIOINFORMATICS

Repetitive Antigen Stimulation Induces Stepwise Transcriptome Diversification but Preserves a Core Signature of Memory CD8+ T Cell Differentiation

(2010) Thomas C. Wirth et al.   IMMUNITY

Memory T cells persisting within the brain after local infection show functional adaptations to their tissue of residence

(2010) L. M. Wakim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates

(2008) Surojit Sarkar et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Memory CD8 T-cell compartment grows in size with immunological experience

(2008) Vaiva Vezys et al.   NATURE