Crosstalk between Noxa, Bcl-2, and ceramide in mediating p53-dependent apoptosis in Molt-4 human T-cell leukemia

Noxa: Role in Cancer Pathogenesis and Treatment

(2018) Rami Z. Morsi et al.   CURRENT CANCER DRUG TARGETS

Lipotoxic very-long-chain ceramides cause mitochondrial dysfunction, oxidative stress, and cell death in cardiomyocytes

(2018) Brittany A. Law et al.   FASEB JOURNAL

Genomic alterations during p53-dependent apoptosis induced by γ-irradiation of Molt-4 leukemia cells

(2017) Rouba Hage-Sleiman et al.   PLoS One

Role of sphingomyelinase in mitochondrial ceramide accumulation during reperfusion

(2016) I. Ramírez-Camacho et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Ceramide channels and mitochondrial outer membrane permeability

(2016) Marco Colombini   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Diverting CERT-mediated ceramide transport to mitochondria triggers Bax-dependent apoptosis

(2016) Amrita Jain et al.   JOURNAL OF CELL SCIENCE

Pro-apoptotic Noxa is involved in ablative focal irradiation-induced lung injury

(2016) Jee-Youn Kim et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Reduced transcriptional activity in the p53 pathway of senescent cells revealed by the MDM2 antagonist nutlin-3

(2016) Baoying Huang et al.   Aging-US

Distinct lipid effects on tBid and Bim activation of membrane permeabilization by pro-apoptotic Bax

(2015) Aisha Shamas-Din et al.   BIOCHEMICAL JOURNAL

Folate Stress Induces Apoptosis via p53-dependentde NovoCeramide Synthesis and Up-regulation of Ceramide Synthase 6

(2013) L. Alexis Hoeferlin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Direct Interaction of Bax and Bak Proteins with Bcl-2 Homology Domain 3 (BH3)-only Proteins in Living Cells Revealed by Fluorescence Complementation

(2013) Laura Vela et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bax and Bcl-xL exert their regulation on different sites of the ceramide channel

(2012) Meenu N. Perera et al.   BIOCHEMICAL JOURNAL

Modulation of Ceramide Synthase Activity via Dimerization

(2012) Elad L. Laviad et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Noxa/Bcl-2 Protein Interactions Contribute to Bortezomib Resistance in Human Lymphoid Cells

(2011) Alyson J. Smith et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Transient binding of an activator BH3 domain to the Bak BH3-binding groove initiates Bak oligomerization

(2011) Haiming Dai et al.   JOURNAL OF CELL BIOLOGY

The Methyltransferase Set7/9 (Setd7) Is Dispensable for the p53-Mediated DNA Damage Response In Vivo

(2011) Stefano Campaner et al.   MOLECULAR CELL

Still embedded together binding to membranes regulates Bcl-2 protein interactions

(2010) B Leber et al.   ONCOGENE

Isolation of mitochondria-associated membranes and mitochondria from animal tissues and cells

(2009) Mariusz R Wieckowski et al.   Nature Protocols

Noxa: at the tip of the balance between life and death

(2009) C Ploner et al.   ONCOGENE

De novo N-palmitoylsphingosine synthesis is the major biochemical mechanism of ceramide accumulation following p53 up-regulation

(2008) Shoghag Panjarian et al.   PROSTAGLANDINS & OTHER LIPID MEDIATORS