Article
Public, Environmental & Occupational Health
Hongmei Zeng, Yunning Liu, Lijun Wang, Peng Yin, Baohua Wang, Ruiying Fu, Xianhui Ran, Rongshou Zheng, Siwei Zhang, Jiangmei Liu, Jinling You, Kexin Sun, Shaoming Wang, Li Li, Ru Chen, Wenqiang Wei, Maigeng Zhou, Jing Wu, Jie He
Summary: The National Cancer Data Linkage Platform is a powerful and efficient way to share cancer outcome data, with a high feasibility and match rate. It can improve data collection efficiency and data utilization.
Article
Gastroenterology & Hepatology
Ming Zhang, Can Chen, Zequn Lu, Yimin Cai, Yanmin Li, Fuwei Zhang, Yizhuo Liu, Shuoni Chen, Heng Zhang, Shuhui Yang, Hui Gen, Yuan Jiang, Caibo Ning, Jinyu Huang, Wenzhuo Wang, Linyun Fan, Yi Zhang, Meng Jin, Jinxin Han, Zhen Xiong, Ming Cai, Jiuyang Liu, Chaoqun Huang, Xiaojun Yang, Bin Xu, Heng Li, Bin Li, Xu Zhu, Yongchang Wei, Ying Zhu, Jianbo Tian, Xiaoping Miao
Summary: This study provides a comprehensive functional analysis of splicing quantitative trait loci (sQTLs) in cancer and specifically in colorectal cancer (CRC). The researchers identified genetic variants that control messenger RNA splicing and examined their association with CRC risk. They also conducted biological experiments to investigate the potential mechanisms of these sQTLs and target genes. The study highlights the role of sQTLs in cancer susceptibility and suggests their potential as biomarkers and therapeutic targets.
Article
Public, Environmental & Occupational Health
Tian Bao Yang, Xiu Jing Lin, Jia Ling Lin, Wei-Ti Chen, Fei Fei Huang
Summary: This study examined the core knowledge levels of cancer prevention and control measures among adults in Fujian, China, and identified several factors that influenced this knowledge. The findings suggest that there is a need to improve the general population's understanding of cancer prevention and control measures, particularly among those in rural areas and with lower education levels.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Green & Sustainable Science & Technology
Xiaowei Song, Yongpei Hao
Summary: Vehicle emissions in the Central Plains Urban Agglomeration in China have significantly increased from 1999 to 2015, with different types of vehicles contributing to various pollutants. The spatial distribution of emissions tends to concentrate in urban centers. Comprehensive integrated scenarios are more effective in controlling emissions compared to individual scenarios.
Review
Oncology
Maomao Cao, He Li, Dianqin Sun, Siyi He, Yiwen Yu, Jiang Li, Hongda Chen, Jufang Shi, Jiansong Ren, Ni Li, Wanqing Chen
Summary: Substantial progress has been made in cancer screening in China, but challenges such as low participation rates, uneven distribution of medical resources, inadequate funding, and insufficient screening quality remain. To improve the quality of cancer screening, efforts should focus on strengthening advertising, providing training, optimizing the definition of high-risk populations, integrating new technologies, and implementing appropriate management measures.
Article
Multidisciplinary Sciences
Stefano Guzzinati, Jessica Battagello, Emanuela Bovo, Maddalena Baracco, Susanna Baracco, Eva Carpin, Antonella Dal Cin, Anna Rita Fiore, Alessandra Greco, Giancarla Martin, Laura Memo, Daniele Monetti, Silvia Rizzato, Carmen Stocco, Sara Zamberlan, Manuel Zorzi, Massimo Rugge
Summary: Population-based cancer registration methods follow international rules and often adopt digital processing methods for efficient case recording. This study examines the performance of digital processing (DP) at the Veneto Tumor Registry, comparing it with registrars' assessments (RAs). The results show a high level of concordance between DP and RAs in cancer status, topography, and morphology. The study highlights the importance of good-quality clinical information and regular interdisciplinary monitoring for the efficiency and reliability of digital cancer registration.
Review
Endocrinology & Metabolism
Chunlu Yan, Yao Shi, Lingqing Yuan, Donghui Lv, Bai Sun, Jiayu Wang, Xiyan Liu, Fangyu An
Summary: Mitochondria play a crucial role in providing cellular energy and maintaining the balance between osteogenesis and osteoclast activity. Mitochondrial dysfunction disrupts this balance and contributes to the pathogenesis of osteoporosis. Targeted therapy of mitochondria in osteoporosis can provide novel strategies for prevention and treatment of this disease.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Review
Cell Biology
Renjun Gu, Yawen Xia, Pengfei Li, Defang Zou, Keqin Lu, Lang Ren, Hongru Zhang, Zhiguang Sun
Summary: Gastric cancer is a common type of cancer with surgery as the main treatment method. However, it is expensive and painful, and patients often experience recurrence. Ferroptosis, a form of cell death dependent on iron, provides a new perspective in cancer therapy. This review summarizes the latest findings on ferroptosis regulation in gastric cancer, discusses the potential of drugs and genes in inducing ferroptosis for treatment and drug resistance, explores the relationship between ferroptosis and the tumor microenvironment in gastric cancer, and suggests areas for future research to accelerate the clinical utility of ferroptosis induction as a treatment strategy for gastric cancer.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2022)
Article
Public, Environmental & Occupational Health
He-ran Wang, Meng-chun Gong, Jing-Yuan Sun, Jian Sun, Yi Guo, Li Liu, Hong Zhu
Summary: After recruiting the Guangdong medical aid team, Honghu implemented the 'Four-Early' and 'Four-centralization' management measures, which effectively increased the recovery rate and reduced mortality among COVID-19 patients. This successful strategy, known as the 'Honghu Model,' can be generalized for worldwide prevention and management of COVID-19.
ANTIMICROBIAL RESISTANCE AND INFECTION CONTROL
(2021)
Review
Oncology
Maomao Cao, He Li, Dianqin Sun, Siyi He, Xinxin Yan, Fan Yang, Shaoli Zhang, Changfa Xia, Lin Lei, Ji Peng, Wanqing Chen
Summary: Cancer has become the leading cause of death in China, with significant changes in cancer epidemiology. Lung, colorectal, and gastric cancers are the most common types, while lung, liver, and stomach cancers are the deadliest. The 5-year survival rate for cancer has significantly improved in recent decades. Modifiable risk factors for cancer development include infectious agents, smoking, alcohol consumption, obesity, unhealthful dietary habits, and inadequate physical activity. The Chinese government has made efforts to reduce the cancer burden.
CANCER BIOLOGY & MEDICINE
(2022)
Article
Clinical Neurology
Bao-Hua Chao, Feng Yan, Yang Hua, Jian-Min Liu, Ge Yang, Xun-Ming Ji, Bin Peng, Guo-Guang Zhao, Yong-Jun Wang, De-Zhi Kang, Yi-Long Wang, Jin-Sheng Zeng, Lan Chu, Tian-Xiao Li, Yu-Ming Xu, Ming Liu, Li He, Yun Xu, Jiang Wu, Min Lou, Wei Yue, Lei Cao, Wen-Jun Tu, Long-De Wang
Summary: The China Stroke Prevention Project Committee has been actively promoting stroke prevention and control in China. With over 8.3 million people screened and followed up from 2012 to 2018, the committee has helped establish 380 stroke centers in mainland China and improved stroke care quality through monitoring and reporting. Further nationwide promotion of the program is needed to continue the progress.
INTERNATIONAL JOURNAL OF STROKE
(2021)
Review
Cell Biology
Qiang Zhang, Chuanchi Wang, Yan Yang, Ruihan Xu, Ziyun Li
Summary: Gastric cancer is a prominent disease in tumor immunotherapy, and long non-coding RNAs (lncRNAs) may play a crucial role in the prognosis and drug resistance of gastric cancer immunotherapy.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2023)
Article
Medicine, General & Internal
You-Qing Wang, Hui-Zhang Li, Wei-Wei Gong, Yao-Yao Chen, Chen Zhu, Le Wang, Jie-Ming Zhong, Ling-Bin Du
Summary: The study analyzed the cancer incidence and mortality rates in Zhejiang Province, China in 2016. The most common cancers in the region were lung cancer, female breast cancer, thyroid cancer, colorectal cancer, prostate cancer, liver cancer, and stomach cancer. Effective prevention and control measures should be tailored to the different characteristics of urban and rural cancers.
CHINESE MEDICAL JOURNAL
(2021)
Article
Public, Environmental & Occupational Health
Yitian Guo, Deqiang Ye, Guifang Yang, Guozhen Liu, Xiaochen Cui, Shiyun Tan, Yi Guo
Summary: This study investigated the epidemiological features of a cluster of acute appendicitis among Tibetan students in a high school in eastern China, highlighting mutual contact with patients as an important risk factor and fecal-oral infection as a potential transmission route. Targeted measures were found to effectively control and prevent the cluster, demonstrating the infectious disease nature of the condition.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Public, Environmental & Occupational Health
Yujun Wei, Zhonghua Ye, Meng Cui, Xiaokun Wei
Summary: The COVID-19 pandemic has spread globally, causing negative impacts on economy and health. China effectively controlled the outbreak through grid governance measures, allowing life and production to return to normal. Research shows that while grid-based governance measures are effective in different cities, there are also limitations and challenges to consider.
JOURNAL OF PUBLIC HEALTH
(2021)