Drug Concentration Thresholds Predictive of Therapy Failure and Death in Children With Tuberculosis: Bread Crumb Trails in Random Forests

A Combination Regimen Design Program Based on Pharmacodynamic Target Setting for Childhood Tuberculosis: Design Rules for the Playground

(2016) Shashikant Srivastava et al.   CLINICAL INFECTIOUS DISEASES

A Faropenem, Linezolid, and Moxifloxacin Regimen for Both Drug-Susceptible and Multidrug-Resistant Tuberculosis in Children: FLAME Path on the Milky Way

(2016) Devyani Deshpande et al.   CLINICAL INFECTIOUS DISEASES

Concentration-Dependent Synergy and Antagonism of Linezolid and Moxifloxacin in the Treatment of Childhood Tuberculosis: The Dynamic Duo

(2016) Devyani Deshpande et al.   CLINICAL INFECTIOUS DISEASES

Low Serum Concentrations of Rifampicin and Pyrazinamide Associated with Poor Treatment Outcomes in Children with Tuberculosis Related to HIV Status

(2016) Geetha Ramachandran et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Challenges in childhood tuberculosis

(2015) S. Swaminathan et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Pediatric tuberculous meningitis: Model-based approach to determining optimal doses of the anti-tuberculosis drugs rifampin and levofloxacin for children

(2015) RM Savic et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Impact of Nonlinear Interactions of Pharmacokinetics and MICs on Sputum Bacillary Kill Rates as a Marker of Sterilizing Effect in Tuberculosis

(2014) Emmanuel Chigutsa et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pharmacokinetics of First-Line Antituberculosis Drugs in HIV-Infected Children with Tuberculosis Treated with Intermittent Regimens in India

(2014) Geetha Ramachandran et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Therapeutic Drug Monitoring in the Treatment of Tuberculosis: An Update

(2014) Abdullah Alsultan et al.   DRUGS

Global control of tuberculosis: from extensively drug-resistant to untreatable tuberculosis

(2014) Keertan Dheda et al.   Lancet Respiratory Medicine

Age, nutritional status and INH acetylator status affect pharmacokinetics of anti-tuberculosis drugs in children

(2013) G. Ramachandran et al.   INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE

Serum Drug Concentrations Predictive of Pulmonary Tuberculosis Outcomes

(2013) J. G. Pasipanodya et al.   JOURNAL OF INFECTIOUS DISEASES

Meta-Analysis of Clinical Studies Supports the Pharmacokinetic Variability Hypothesis for Acquired Drug Resistance and Failure of Antituberculosis Therapy

(2012) Jotam G. Pasipanodya et al.   CLINICAL INFECTIOUS DISEASES

Pharmacokinetic Mismatch Does Not Lead to Emergence of Isoniazid- or Rifampin-Resistant Mycobacterium tuberculosis but to Better Antimicrobial Effect: a New Paradigm for Antituberculosis Drug Scheduling

(2011) Shashikant Srivastava et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Multidrug-Resistant Tuberculosis Not Due to Noncompliance but to Between-Patient Pharmacokinetic Variability

(2011) Shashikant Srivastava et al.   JOURNAL OF INFECTIOUS DISEASES

In SilicoChildren and the Glass Mouse Model: Clinical Trial Simulations To Identify and Individualize Optimal Isoniazid Doses in Children with Tuberculosis

(2010) Prakash M. Jeena et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

An Oracle: Antituberculosis Pharmacokinetics-Pharmacodynamics, Clinical Correlation, and Clinical Trial Simulations To Predict the Future

(2010) Jotam Pasipanodya et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Paradoxical Effect of Isoniazid on the Activity of Rifampin-Pyrazinamide Combination in a Mouse Model of Tuberculosis

(2009) D. Almeida et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY