Article
Clinical Neurology
Ana Abicic, Ivan Adamec, Mario Habek
Summary: Patients with acute ophthalmoplegia after COVID-19 vaccination should be screened for anti-GQ1b antibodies. If present, intravenous immunoglobulins should be administered to hasten clinical improvement.
NEUROLOGICAL SCIENCES
(2022)
Review
Environmental Sciences
Zheng Li, Xingye Li, Jianxiong Shen, Matthew T. V. Chan, William Ka Kei Wu
Summary: From the first report of COVID-19 to October 8, 2020, there were 7 cases of Miller Fisher syndrome (MFS) associated with COVID-19, mainly from Europe, with symptoms including sensory abnormalities, ataxia, blurred vision, etc. More research is needed to establish the epidemiological linkage.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Review
Medicine, General & Internal
Ahsun Rizwan Siddiqi, Tehrim Khan, Muhammad Junaid Tahir, Muhammad Sohaib Asghar, Md. Saiful Islam, Zohaib Yousaf
Summary: This case report describes a rare case of Miller Fisher syndrome (MFS) occurring after COVID-19 vaccination and highlights the need for further research to establish a temporal association.
Review
Clinical Neurology
Jee-Eun Kim, Byeol-A Yoon, Yoo Hwan Kim, Jong Kuk Kim, Jong Seok Bae
Summary: This study aimed to identify and characterize Miller Fisher syndrome (MFS) following COVID-19 vaccination. The findings suggest that MFS following COVID-19 vaccination has different pathophysiology compared to MFS following COVID-19 infection and Guillain-Barre Syndrome (GBS) following COVID-19 vaccination. Considering the rare incidence and diagnostic challenges of this neurological syndrome, it should be recognized as an adverse event of COVID-19 vaccination.
ACTA NEUROLOGICA SCANDINAVICA
(2022)
Article
Immunology
Lucy Faulkner, Simon Scott, Neil Flint
Summary: This article presents a case of Millere-Fisher syndrome following COVID-19 infection, highlighting the importance of early recognition and immunological treatment for improved prognosis.
MICROBES AND INFECTION
(2022)
Review
Biotechnology & Applied Microbiology
Hao Liang, Yuanbo Cao, Wei Zhong, Zhenwang Ma, Jia Liu, Hong Chen
Summary: Miller-Fisher syndrome (MFS) is a rare variant of Guillain-Barre syndrome (GBS) that can occur after COVID-19 vaccination. This case report describes a 64-year-old Chinese man who developed MFS-GBS overlap syndrome 12 days after receiving the second dose of inactivated COVID-19 vaccine. The patient was successfully treated with intravenous immunoglobulin and acupuncture and made a complete recovery. Close monitoring of neurological complications following COVID-19 vaccination is important due to the potentially disabling and lethal effects.
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2022)
Article
Clinical Neurology
Kentaro Nanatsue, Makoto Takahashi, Sakiko Itaya, Keisuke Abe, Akira Inaba
Summary: This case report highlights a potential neurological side effect of the Moderna COVID-19 vaccine, as the patient developed Miller-Fisher syndrome after vaccination.
Review
Clinical Neurology
Ciro Maria Noioso, Liliana Bevilacqua, Gabriella Maria Acerra, Paola Della Valle, Marina Serio, Claudia Vinciguerra, Giuseppe Piscosquito, Antonella Toriello, Paolo Barone, Aniello Iovino
Summary: Miller Fisher syndrome (MFS) is a rare variant of Guillain-Barre syndrome (GBS), characterized by ataxia, areflexia, and ophthalmoparesis. This review provides a comprehensive overview of MFS, including its clinical characteristics, neurophysiology, treatment, and prognosis, with a focus on recent developments related to COVID-19.
FRONTIERS IN NEUROLOGY
(2023)
Review
Clinical Neurology
Panayiota Neophytou, Artemios Artemiadis, Georgios M. Hadjigeorgiou, Panagiotis Zis
Summary: This study systematically reviewed Miller Fisher syndrome (MFS) cases in the context of COVID-19 infection or vaccination. It found that MFS can occur after both COVID-19 infection and vaccination, with a higher prevalence in male and middle-aged patients. The prognosis is excellent with treatment or even without treatment.
ACTA NEUROLOGICA BELGICA
(2023)
Review
Clinical Neurology
Dorsa Alijanzadeh, Afsaneh Soltani, Fatemeh Afra, Fardis Salmanpour, Amir Hossein Loghman, Noosha Samieefar, Nima Rezaei
Summary: Miller Fisher syndrome (MFS) after COVID-19 immunization has favorable outcomes and good prognosis. However, more attention should be paid to MFS as an adverse effect of the vaccination. MFS should be considered in the differential diagnosis for patients with a history of recent COVID-19 vaccination and any of the ocular complaints, ataxia, or loss of reflexes, especially for male patients in their 60s and 70s.
Review
Immunology
Miao Yu, Shuang Nie, Yue Qiao, Ying Ma
Summary: This study retrospectively analyzed reported Guillain-Barre syndrome (GBS) cases occurring after COVID-19 vaccination. The analysis revealed that GBS mostly occurred after the first dose of the vaccination (90%), particularly with DNA vaccines (63%). It was more common in middle-aged and elderly individuals (mean age: 54.5 years) and in men (60%). The mean time from vaccination to onset was 12.3 days. Monitoring for GBS following vaccination is recommended to establish the true incidence and association between GBS and COVID-19 vaccination.
FRONTIERS IN IMMUNOLOGY
(2023)
Article
Medicine, General & Internal
Cuong Tran, Blake Drury, Ho-Wang Yuen, Johanna Rosenthal, Michael M. Neeki
Summary: The case report describes a unique case of Miller-Fisher Syndrome associated with COVID-19, presenting with bilateral facial palsy, dysarthria, hemiparesis, and ataxia. Recovery was improved after a five-day course of IVIG therapy combined with physical, occupational, and speech therapy.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2021)
Article
Medicine, General & Internal
Surina Kajani, Raheem Kajani, Chin-Wei Huang, Tu Tran, Antonio K. Liu
Summary: Although Miller Fisher syndrome cases have been reported during the COVID-19 pandemic, the presence of anti-GQ1b antibody has not been confirmed yet, and there is no direct evidence of its association with the coronavirus. The lack of GQ1b is considered as an indirect proof that SARS-CoV-2 may be the infection preceding demyelination, but a novel antigen remains to be identified through further research.
CUREUS JOURNAL OF MEDICAL SCIENCE
(2021)
Article
Immunology
Pimchanok Kulsirichawaroj, Oranee Sanmaneechai, Orasri Wittawatmongkol, Kulkanya Chokephaibulkit
Summary: A 16-year-old Thai girl developed facial palsy, lower motor neuron lesion, and numbness after receiving the BNT162b2 mRNA vaccine. Examination revealed involvement of multiple cranial nerves, suggesting a rare variant of Guillain-Barre syndrome. Treatment with intravenous immunoglobulin was successful.
Article
Clinical Neurology
Jean-Michel Vallat, Nathalie Deschamps, Frederic Taithe, Laurence Richard, Mathilde Duchesne, Laurent Magy, Stephane Mathis
Summary: This study aims to investigate the pathological characteristics of acute and chronic ataxic peripheral neuropathy at the level of the node of Ranvier. The results indicate that an immune-mediated dysimmune process is involved in the pathogenesis of this neuropathy, particularly in the paranodal and nodal regions. These findings suggest the importance of complement-mediated dysfunction/disruption of the nodal region in the development of this subtype of autoimmune neuropathy.
JOURNAL OF THE NEUROLOGICAL SCIENCES
(2022)
Letter
Clinical Neurology
Giovanni Furlanis, Paolo Manganotti, Milos Ajcevic, Jessica Rossi, Chiara Vincenzi, Marcello Naccarato, Guido Bigliardi, Andrea Zini
CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES
(2022)
Article
Clinical Neurology
Antonio Granato, Laura D'Acunto, Maria Elisa Morelli, Giulia Bellavita, Franco Cominotto, Paolo Manganotti
Summary: The diagnosis of NOS headaches in the Emergency Department is common despite specialist visits, with only 37% of patients receiving a precise diagnosis. Neurologists made diagnoses slightly more frequently than non-neurologists, but the ED physician often did not report specialist diagnoses in the discharge sheet. This leads to an overestimation of NOS headaches and a loss of specific diagnoses.
ACTA NEUROLOGICA BELGICA
(2022)
Letter
Clinical Neurology
Tommaso Cillotto, Giovanni Furlanis, Alex Buoite Stella, Carlo Lugnan, Paola Caruso, Roberta Pozzi Mucelli, Marcello Naccarato, Paolo Manganotti
CANADIAN JOURNAL OF NEUROLOGICAL SCIENCES
(2022)
Article
Clinical Neurology
Alex Buoite Stella, Giovanni Furlanis, Nicolo Arjuna Frezza, Romina Valentinotti, Milos Ajcevic, Paolo Manganotti
Summary: The study revealed that dysautonomia may be a possible complication in post-COVID individuals, presenting symptoms such as orthostatic intolerance, sudomotor dysfunction, gastrointestinal issues, and pupillomotor dysfunction. Patients with neurological symptoms had a higher COMPASS-31 score due to more severe orthostatic intolerance symptoms compared to those without neurological symptoms.
JOURNAL OF NEUROLOGY
(2022)
Letter
Clinical Neurology
Luca Panebianco, Laura D'Acunto, Bruna Nucera, Fabrizio Rinaldi, Paolo Manganotti, Raffaele Nardone, Francesco Brigo
ACTA NEUROLOGICA BELGICA
(2023)
Review
Otorhinolaryngology
Paola Potente, Alex Buoite Stella, Monica Vidotto, Michelle Passerini, Giovanni Furlanis, Marcello Naccarato, Paolo Manganotti
Summary: Swallowing disorders are common in neurological diseases, and ultrasound imaging has been suggested as a useful tool for evaluating dysphagia. It provides measures of both static and dynamic anatomical components, aiding in the identification and early rehabilitation of swallowing difficulties. Studies have shown that ultrasound imaging correlates well with clinical evaluation and has prognostic and rehabilitation potential. However, due to the variety of tools, methods, and techniques used in the reviewed studies, standard procedures and outcomes have yet to be established.
Article
Clinical Neurology
Sasha Olivo, Giovanni Furlanis, Alex Buoite Stella, Martina Fabris, Romina Milanic, Gianluigi Zanusso, Paolo Manganotti
Summary: We present a case of a 70-year-old man who developed rapidly progressing CJD with SARS-CoV-2 co-infection, ultimately leading to his death after 15 days of hospitalization. This rare clinical presentation highlights the challenges in diagnosis.
ACTA NEUROLOGICA BELGICA
(2023)
Review
Urology & Nephrology
Michele Bertolotto, Irene Campo, Nicola Pavan, Alex Buoite Stella, Vito Cantisani, Francesco Maria Drudi, Maria Assunta Cova, Lorenzo E. Derchi
Summary: This systematic review aims to assess the incidence of benign tumors, malignant tumors, and non-neoplastic lesions in asymptomatic postpuberal males with incidentally detected testicular lesions. The study found a higher incidence of benign lesions with a diameter of <5 mm. Further research is needed to better understand the biology and management strategy for small testicular lesions.
EUROPEAN UROLOGY FOCUS
(2023)
Article
Clinical Neurology
Sasha Olivo, Alex Buoite Stella, Stefania Pavan, Matteo Cegalin, Giovanni Furlanis, Marta Cheli, Marinella Tomaselli, David Stokelj, Paolo Manganotti
Summary: The study investigated the prognostic value of admission neutrophil-to-lymphocyte ratio (NLR) in patients with status epilepticus, finding that NLR is associated with length of hospitalization and need for ICU admission.
SEIZURE-EUROPEAN JOURNAL OF EPILEPSY
(2023)
Article
Clinical Neurology
Giovanni Furlanis, Alex Buoite Stella, Francesco Biaduzzini, Giulia Bellavita, Nicolo Arjuna Frezza, Sasha Olivo, Alina Menichelli, Alberta Lunardelli, Milos Ajcevic, Paolo Manganotti
Summary: This study aimed to investigate EEG alterations in individuals with self-reported cognitive deficit after COVID-19. Among 90 patients attending a post-COVID neurology service, 20 patients with brain fog 4 weeks after non-severe COVID-19 infection were studied. EEG analysis revealed abnormalities in 65% of the sample, with 69% showing slowing activity and 31% presenting epileptic discharges in frontal areas. None of the patients exhibited DWI MRI lesions.
NEUROLOGICAL SCIENCES
(2023)
Article
Green & Sustainable Science & Technology
Manzan Marco, Atlas Ramezani, Alex Buoite Stella, Amedeo Pezzi
Summary: This study analyzed common refurbishment interventions applied to a social housing building in Italy and considered internal comfort during the summer season in the design phase. The results showed that both building insulation and climatic change affected heating consumption, but building insulation had little effect on internal comfort while climate change increased the percentage of hours of discomfort.
Review
Neurosciences
Paolo Manganotti, Gabriele Garascia, Giovanni Furlanis, Alex Buoite Stella
Summary: IVIg therapy has been found to be an effective and safe treatment option for neurological disorders related to COVID-19.
FRONTIERS IN NEUROSCIENCE
(2023)
Article
Geriatrics & Gerontology
Roberto Luzzati, Marina De Luca, Gianfranco Sanson, Massimo Borelli, Gianni Biolo, Donatella Giacomazzi, Verena Zerbato, Stefano Di Bella
Summary: This study explores the association between home corticosteroid treatment and 30-day mortality in hospitalized patients with COVID-19 pneumonia. The results show a lower risk of death in patients receiving home corticosteroids, especially in those over 77 years of age.
AGING CLINICAL AND EXPERIMENTAL RESEARCH
(2022)
