NLRP1 inflammasome contributes to chronic stress-induced depressive-like behaviors in mice

The chemokine CXCL1 and its receptor CXCR2 contribute to chronic stress-induced depression in mice

(2019) Hui-Hui Chai et al.   FASEB JOURNAL

The Role of Chemokines in the Pathophysiology of Major Depressive Disorder

(2019) Vladimir M. Milenkovic et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Antidepressant-like Effects Induced by Chronic Blockade of the Purinergic 2X7 Receptor through Inhibition of Non-like Receptor Protein 1 Inflammasome in Chronic Unpredictable Mild Stress Model of Depression in Rats

(2019) Feyza Aricioglu et al.   Clinical Psychopharmacology and Neuroscience

The Role of BDNF in the Neuroimmune Axis Regulation of Mood Disorders

(2019) Yang Jin et al.   Frontiers in Neurology

Antidepressant-like effects of agmatine and NOS inhibitors in chronic unpredictable mild stress model of depression in rats: The involvement of NLRP inflammasomes

(2019) Ceren Sahin Ozkartal et al.   BRAIN RESEARCH

Therapeutic Strategies for Treatment of Inflammation-related Depression

(2018) Miroslav Adzic et al.   Current Neuropharmacology

Sinomenine exerts anticonvulsant profile and neuroprotective activity in pentylenetetrazole kindled rats: involvement of inhibition of NLRP1 inflammasome

(2018) Bo Gao et al.   Journal of Neuroinflammation

Efficacy and Safety of Intranasal Esketamine Adjunctive to Oral Antidepressant Therapy in Treatment-Resistant Depression

(2018) Ella J. Daly et al.   JAMA Psychiatry

Brain-Derived Neurotrophic Factor and Major Depressive Disorder: Evidence from Meta-Analyses

(2018) Taro Kishi et al.   Frontiers in Psychiatry

Microglial recruitment of IL-1β-producing monocytes to brain endothelium causes stress-induced anxiety

(2017) D B McKim et al.   MOLECULAR PSYCHIATRY

Gene deficiency and pharmacological inhibition of caspase-1 confers resilience to chronic social defeat stress via regulating the stability of surface AMPARs

(2017) M-X Li et al.   MOLECULAR PSYCHIATRY

CXCL1/CXCR2 signaling in pathological pain: Role in peripheral and central sensitization

(2017) Rangel L. Silva et al.   NEUROBIOLOGY OF DISEASE

Adult hippocampal neurogenesis: an important target associated with antidepressant effects of exercise

(2017) Lina Sun et al.   REVIEWS IN THE NEUROSCIENCES

Chronic glucocorticoids exposure enhances neurodegeneration in the frontal cortex and hippocampus via NLRP-1 inflammasome activation in male mice

(2016) Wen Hu et al.   BRAIN BEHAVIOR AND IMMUNITY

Inflammation in Depression and the Potential for Anti-Inflammatory Treatment

(2016) Ole Kohler et al.   Current Neuropharmacology

Depressive Rumination, the Default-Mode Network, and the Dark Matter of Clinical Neuroscience

(2015) J. Paul Hamilton et al.   BIOLOGICAL PSYCHIATRY

NLRP3 Inflammasome Mediates Chronic Mild Stress-Induced Depression in Mice via Neuroinflammation

(2015) Y. Zhang et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

The pathogenic role of the inflammasome in neurodegenerative diseases

(2015) Leslie C. Freeman et al.   JOURNAL OF NEUROCHEMISTRY

Acid-sensing ion channel 1a contributes to the effect of extracellular acidosis on NLRP1 inflammasome activation in cortical neurons

(2015) Yu-Chan Wang et al.   Journal of Neuroinflammation

Social defeat promotes a reactive endothelium in a brain region-dependent manner with increased expression of key adhesion molecules, selectins and chemokines associated with the recruitment of myeloid cells to the brain

(2015) C.M. Sawicki et al.   NEUROSCIENCE

Anti-inflammatory Intervention in Depression—Reply

(2015) Ole Köhler et al.   JAMA Psychiatry

Microglial NLRP3 inflammasome activation mediates IL-1β-related inflammation in prefrontal cortex of depressive rats

(2014) Ying Pan et al.   BRAIN BEHAVIOR AND IMMUNITY

Current perspectives on the link between neuroinflammation and neurogenesis

(2014) Brian Wang et al.   METABOLIC BRAIN DISEASE

Rapid Regulation of Depression-Associated Genes in a New Mouse Model Mimicking Interferon-α-Related Depression in Hepatitis C Virus Infection

(2014) Carolina Hoyo-Becerra et al.   MOLECULAR NEUROBIOLOGY

Brain-derived neurotrophic factor: a bridge between inflammation and neuroplasticity

(2014) Francesca Calabrese et al.   Frontiers in Cellular Neuroscience

Effect of Anti-inflammatory Treatment on Depression, Depressive Symptoms, and Adverse Effects

(2014) Ole Köhler et al.   JAMA Psychiatry

Inflammasomes in neuroinflammation and changes in brain function: a focused review

(2014) Gaurav Singhal et al.   Frontiers in Neuroscience

The Epidemiology of Depression Across Cultures

(2013) Ronald C. Kessler et al.   Annual Review of Public Health

NLRP3 inflammasome is activated in mononuclear blood cells from patients with major depressive disorder

(2013) Elísabet Alcocer-Gómez et al.   BRAIN BEHAVIOR AND IMMUNITY

Nrf2 participates in depressive disorders through an anti-inflammatory mechanism

(2013) María Dolores Martín-de-Saavedra et al.   PSYCHONEUROENDOCRINOLOGY

Brain-Derived Neurotrophic Factor Signaling and Subgenual Anterior Cingulate Cortex Dysfunction in Major Depressive Disorder

(2012) Adam Tripp et al.   AMERICAN JOURNAL OF PSYCHIATRY

A meta-analysis of differences in IL-6 and IL-10 between people with and without depression: Exploring the causes of heterogeneity

(2012) Sarah A. Hiles et al.   BRAIN BEHAVIOR AND IMMUNITY

Pro-inflammatory cytokines as predictors of antidepressant effects of exercise in major depressive disorder

(2012) C D Rethorst et al.   MOLECULAR PSYCHIATRY

Inflammasomes in health and disease

(2012) Till Strowig et al.   NATURE

The Default Mode Network and Recurrent Depression: A Neurobiological Model of Cognitive Risk Factors

(2012) Igor Marchetti et al.   NEUROPSYCHOLOGY REVIEW

Individual differences in chronically defeated male mice: Behavioral, endocrine, immune, and neurotrophic changes as markers of vulnerability to the effects of stress

(2012) Eneritz Gómez-Lázaro et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS

The Inflammasome NLRs in Immunity, Inflammation, and Associated Diseases

(2011) Beckley K. Davis et al.   Annual Review of Immunology

Heightened inflammasome activation is linked to age-related cognitive impairment in Fischer 344 rats

(2011) Lana J Mawhinney et al.   BMC NEUROSCIENCE

Sickness behaviour is induced by a peripheral CXC-chemokine also expressed in Multiple Sclerosis and EAE

(2010) Sandra J. Campbell et al.   BRAIN BEHAVIOR AND IMMUNITY

The Inflammasomes

(2010) Kate Schroder et al.   CELL

Altered expression of genes involved in inflammation and apoptosis in frontal cortex in major depression

(2010) R C Shelton et al.   MOLECULAR PSYCHIATRY

The hippocampus in major depression: evidence for the convergence of the bench and bedside in psychiatric research?

(2010) G MacQueen et al.   MOLECULAR PSYCHIATRY

Inflammation Causes Mood Changes Through Alterations in Subgenual Cingulate Activity and Mesolimbic Connectivity

(2009) Neil A. Harrison et al.   BIOLOGICAL PSYCHIATRY

Inflammation and Its Discontents: The Role of Cytokines in the Pathophysiology of Major Depression

(2009) Andrew H. Miller et al.   BIOLOGICAL PSYCHIATRY

A Meta-Analysis of Cytokines in Major Depression

(2009) Yekta Dowlati et al.   BIOLOGICAL PSYCHIATRY

Knockdown of brain-derived neurotrophic factor in specific brain sites precipitates behaviors associated with depression and reduces neurogenesis

(2009) D Taliaz et al.   MOLECULAR PSYCHIATRY

Associations of Depression With C-Reactive Protein, IL-1, and IL-6: A Meta-Analysis

(2009) M Bryant Howren et al.   PSYCHOSOMATIC MEDICINE

Brain-derived neurotrophic factor, stress and depression: A minireview

(2008) Burak Yuluğ et al.   BRAIN RESEARCH BULLETIN

The inflammatory & neurodegenerative (I&ND) hypothesis of depression: leads for future research and new drug developments in depression

(2008) Michael Maes et al.   METABOLIC BRAIN DISEASE