Article
Food Science & Technology
Nabab Khan, Amit Kumar Singh, Ankit Saneja
Summary: The study demonstrates that LAA-cyclodextrin inclusion complex-incorporated nanofibers (NFs) can improve the stability and antioxidant potential of L-Ascorbic acid (LAA). The encapsulation of LAA within HP-beta-CD cavities enhances its thermal stability and antioxidant activity. This research provides promising avenues for addressing the limitations of LAA in therapeutic and food applications.
Article
Materials Science, Characterization & Testing
Habibeh Azizi, Arash Koocheki, Behrouz Ghorani
Summary: In this study, gluten/zein (G/Z) blends were electrospun with acetic acid as a solvent. The effects of zein content on the morphology, structure and properties of assembled gluten nanofibers were investigated. The presence and distribution of both proteins in the G/Z nanofibers were confirmed. The results showed that the diameter and surface morphology of the nanofibers varied with the zein content. The alpha-helix structure, crystallinity and hydrophobicity increased with increasing zein to gluten ratio. DSC analysis revealed a single glass transition temperature in the G/Z nanofibers, indicating the miscibility of the blend. The flexibility of the fibers increased as the amount of zein decreased.
Article
Chemistry, Applied
Zehra Irem Yildiz, Fuat Topuz, Mehmet Emin Kilic, Engin Durgun, Tamer Uyar
Summary: In this study, beta-carotene was encapsulated in electrospun cyclodextrin nanofibers to increase its water solubility and photostability. The beta-carotene/CD nanofibers demonstrated antioxidant activity and protection against UV radiation. This work presents a water-borne electrospinning method to stabilize beta-carotene against UV-mediated oxidation.
Article
Materials Science, Multidisciplinary
Radek Jirkovec, Jakub Erben, Petr Sajdl, Jiri Chaloupek, Jiri Chvojka
Summary: The experiment studied the effects of different solvent systems and two electrospinning methods on the surface energy, resulting in nanofibrous materials with varying surface energies and different degrees of hydrophilicity/hydrophobicity in the produced fiber layers.
MATERIALS & DESIGN
(2021)
Article
Chemistry, Multidisciplinary
Edurne Gonzalez, Aitor Barquero, Belen Munoz-Sanchez, Maria Paulis, Jose Ramon Leiza
Summary: Green electrospinning is a new technology that uses a template polymer to spin a polymer from an aqueous dispersion, providing an environmentally friendly and safe method for spinning hydrophobic polymers. The study found that factors such as template polymer molar mass, total solids content, and particle/template ratio influence fiber morphology, while surfactant used, surface functionality of polymer particles, and particle size distribution also play a role. Additionally, viscosity of the initial blend, particle packing, and surface chemistry of polymer particles are important for obtaining high-quality nanofibers.
Article
Biophysics
Shuang Gao, Yanyan Liu, Jingyu Jiang, Xiaoming Li, Fei Ye, Ying Fu, Lixia Zhao
Summary: The study successfully prepared thiram/HP/3CD-ICNF nanofiber through electrospinning, establishing a quick dissolving drug delivery system. The system showed improved water solubility, thermal stability, and antifungal activity, contributing to the development of rapidly dissolving green pesticides.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2021)
Article
Green & Sustainable Science & Technology
Shuang Gao, Lei Zong, Yuhang Zhang, Yang Zhang, Xinyu Guo, Guanhua Guo, Lixia Zhao, Fei Ye, Ying Fu
Summary: Pentachloronitrobenzene/hydroxypropyl-γ-cyclodextrin inclusion complex nanofibers (PCNB/HPfiCDIC-NF) were prepared via polymer-free electrospinning to establish a rapidly dissolving water-based drug delivery system. The formation of PCNB/HPfiCD-IC enhanced the water solubility and thermal stability of PCNB. The antifungal activity of PCNB/HPfiCD-ICNF was 2.13 times higher than that of pure PCNB. The formulation of PCNB/HPfiCD-IC-NF could effectively improve the solvability, thermal stability, and antifungal activity of PCNB.
JOURNAL OF CLEANER PRODUCTION
(2023)
Article
Materials Science, Multidisciplinary
Zhongchen He, Francois Rault, Astha Vishwakarma, Elham Mohsenzadeh, Fabien Salaun
Summary: Poly(vinylidene fluoride) (PVDF)-electrosprayed nanofibers have garnered significant interest for their flexibility and piezoelectric properties compared to other piezoelectric materials. This study investigates the influence of working and formulation parameters on the morphology, crystal structure, and beta-phase generation of PVDF nanofibers. Additionally, it analyzes the dispersion state of PVDF molecular chains in the solvent and its effect on electrospinning results. Furthermore, the study discusses the quantitative impact of nanofiber orientation on piezoelectric properties, finding that the alignment of nanofibers does not affect their piezoelectric performance.
Article
Polymer Science
Muhammad Bkkar, Roman Olekhnovich, Arina Kremleva, Vera Sitnikova, Yakov Kovach, Nikolai Zverkov, Mayya Uspenskaya
Summary: Optimizing the properties of electrospun polymer-perovskite nanofibers is crucial for enhancing the performance of flexible optoelectronic devices. The study investigates the effects of electrospinning setup parameters on various properties of modified polyvinylpyrrolidone nanofibers, including their external structure, perovskite crystallinity, optical properties, thermal properties, shrinkage ratio, mechanical properties, and long-term stability. The results demonstrate that the structure of nanofibers depends on the electrical voltage, collector rotation speed, and process duration. Increasing the electrical voltage or/and the process time improves the perovskite crystallinity and light absorption. The polymer's glass transition temperature is influenced by the embedded perovskite and the collector's rotation speed. The shrinkage ratio and mechanical properties of the nanofibers are controlled by the rotation speed and electrical voltage. The nanofibers exhibit the best mechanical properties with a rotary collector at a rotational speed of 500-750 rpm. They also demonstrate good long-term stability and high thermal stability, with the long-term stability being inversely proportional to the electrical voltage value.
Article
Materials Science, Composites
Francisco Sebastian Navarro Oliva, Leo Picart, Christopher Y. Leon-Valdivieso, Ahmed Benalla, Luc Lenglet, Alejandro Ospina, Jacques Jestin, Fahmi Bedoui
Summary: Nanoreinforced polymers have gained popularity for their enhanced properties in various applications, but dispersion of nanoparticles into polymeric matrices remains a challenge. This study proposes a method using coaxial electrospinning to disperse NPs in PVDF, showing that NP size affects fiber size. Transmission electron microscopy confirms good NP dispersion in the polymer.
POLYMER COMPOSITES
(2021)
Article
Polymer Science
Zahra Norouzi, Majid Abdouss
Summary: Considering the depletion of water resources, wastewater treatment is important for protecting the ecosystem and efficient use of water resources. In this study, beta-cyclodextrin was grafted onto chitosan to form beta-cyclodextrin grafted chitosan, which was further improved by developing nanofibers. The blend nanofibers were fabricated by electrospinning and their performance as molecular filters for removing hazardous materials from wastewater was investigated.
Article
Pharmacology & Pharmacy
Nikolaos D. Bikiaris, Ioanna Koumentakou, Georgia Michailidou, Margaritis Kostoglou, Marilena Vlachou, Panagiotis Barmpalexis, Evangelos Karavas, George Z. Papageorgiou
Summary: In this study, nanofibrous patches were successfully fabricated via electrospinning for the sustained release of leflunomide's active metabolite, teriflunomide. The results showed that teriflunomide was incorporated in an amorphous form inside the nanofibers and exhibited significant molecular interactions with the polyester. The nanofibers demonstrated a biphasic release profile, with an initial burst release followed by sustained release.
Article
Materials Science, Multidisciplinary
Niranjan N. Prabhu, B. Rajendra, S. Anandhan, Krishna Murthy, R. B. Jagadeesh Chandra, Gibin George, B. Sachin Kumar, B. Shivamurthy
Summary: Aging populations and the increase in chronic diseases worldwide require efficient healthcare tools for simple, rapid, and accurate diagnosis and monitoring human health. Gas sensors, specifically metal oxide and ceramic nanofibers, produced through electrospinning, are being explored for potential use in gas sensors for engineering and medical sectors. This research aims to evaluate the effects of various parameters on the physical properties of zinc oxide nanofibers produced through electrospinning, including concentrations of poly(vinyl alcohol) (PVA) and zinc acetate dihydrate (ZnAc2), feed rate, voltage, spinneret tip-to-collector distance (TCD), and pyrolysis temperature.
MATERIALS RESEARCH EXPRESS
(2023)
Article
Biophysics
Javier Garcia, Manuel Felix, Felipe Cordobes, Antonio Guerrero
Summary: This study focuses on the development and characterization of electrospun nanofibrous membranes of bovine serum albumin (BSA) with potential applications in various fields, exploring the impact of non-hazardous reagents on the formation of BSA nanofibers. The addition of ethanol (EtOH) and hydroxypropyl methylcellulose (HPMC) were found to favor the formation of nanofibers, but bead formation was observed in the membranes.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2022)
Article
Engineering, Environmental
Fuat Topuz, Tibor Holtzl, Gyorgy Szekely
Summary: Water pollution by major human activities leading to clean water scarcity is a significant issue. A highly effective sorbent platform based on a nanofibrous membrane comprising hypercrosslinked cyclodextrin networks (HCNs) was developed to address this issue. The HCN membrane demonstrated high sorption performance for scavenging organic micropollutants in polluted water and showed excellent reusability upon treatment with acidic methanol.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Materials Science, Multidisciplinary
Fuat Topuz, Mahmoud A. Abdulhamid, Tibor Holtzl, Gyorgy Szekely
Summary: In this study, the electrospinning parameters and salt addition were explored to investigate their effects on the diameter, morphology, and spinnability of electrospun PI nanofibers. Addition of tetraethylammonium bromide (TEAB) salt significantly increased the conductivity of PI solutions, improved spinability, and resulted in thinner fibers. Molecular dynamic simulations revealed the macromolecular mechanism of improved spinnability and fiber morphology in the presence of an ammonium salt.
MATERIALS & DESIGN
(2021)
Article
Chemistry, Applied
Asli Celebioglu, Tamer Uyar
Summary: The study demonstrated that pullulan/eugenol-gamma CD nanofibers prepared using pullulan and cyclodextrin molecules can effectively retain the volatility of eugenol, providing enhanced thermal stability and antioxidant performance.
FOOD HYDROCOLLOIDS
(2021)
Article
Engineering, Environmental
Fuat Topuz, Tibor Holtzl, Gyorgy Szekely
Summary: Water pollution by major human activities leading to clean water scarcity is a significant issue. A highly effective sorbent platform based on a nanofibrous membrane comprising hypercrosslinked cyclodextrin networks (HCNs) was developed to address this issue. The HCN membrane demonstrated high sorption performance for scavenging organic micropollutants in polluted water and showed excellent reusability upon treatment with acidic methanol.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Engineering, Environmental
Fuat Topuz, Mahmoud A. Abdulhamid, Rifan Hardian, Tibor Holtzl, Gyorgy Szekely
Summary: The study demonstrated the successful fabrication of nanofibrous air-filtration membranes using intrinsically microporous polyimide with metal-organic frameworks (MOFs), showing efficient removal of VOCs from air. Different polyimides with varying surface areas were synthesized, and the impact of porosity on the sorption kinetics of nanofibers was investigated. Embedding Zr-based MOFs into nanofibers greatly improved the sorption performance for both polar and non-polar VOCs, with molecular modeling studies clarifying the interactions between VOCs and polymer/MOFs. Additionally, the practicality and applicability of the material were assessed by modifying industrial N95 dust masks.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Asli Celebioglu, Antonio Frank Saporito, Tamer Uyar
Summary: Chitosan/pectin/CD-IC nanofibrousfilms, generated by electrospinning with the facilitation of cyclodextrin molecules, showed high swelling and pH-responsive release of curcumin, making them a promising alternative biomaterial with unique properties.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2022)
Article
Medicine, Research & Experimental
Emmy Hsiung, Asli Celebioglu, Mehmet Emin Kilic, Engin Durgun, Tamer Uyar
Summary: In this study, inclusion complexes of Griseofulvin (GSF) with hydroxypropyl-beta-cyclodextrin (HPfiCD) were formed and incorporated into nanofibers with pullulan (PULL) through electrospinning. The resulting PULL/GSF-HPfiCD-IC nanofibers showed improved water solubility and faster release, making them a potential fast-disintegrating dosage formulation for antifungal oral administration.
MOLECULAR PHARMACEUTICS
(2023)
Article
Chemistry, Multidisciplinary
Rohith K. Ramakrishnan, Sundaramoorthy Palanisamy, Nechikkottil S. Sumitha, Akshay Kumar K. Padinjareveetil, S. Sabarinath, Stanislaw Waclawek, Tamer Uyar, Miroslav Cernik, Rajender S. Varma, Jun Young Cheong, Vinod Vellora Thekkae Padil
Summary: With the advancement in technology, miniaturized electronic gadgets capable of high-speed functioning have emerged, especially in the era of 5G. However, the increasing demand for electronics and portable devices has led to the emergence of electromagnetic pollution as a critical issue affecting human health and the environment. To address this problem, sustainable materials that effectively shield electromagnetic radiation while offering high mechanical strength and recyclability are needed. This study introduces freestanding nanocomposite films comprising multiwalled carbon nanotubes with a tree gum/alginate conjugate, which provide an ultraflexible and recyclable platform for electromagnetic interference shielding.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2023)
Article
Food Science & Technology
Zehra Irem Yildiz, Fuat Topuz, Tamer Uyar
Summary: The solubility and stability of catechin were studied using cyclodextrin, and the antioxidant activity of catechin was compared using cyclodextrin inclusion complex nanofibers without polymer.
ACS FOOD SCIENCE & TECHNOLOGY
(2023)
Article
Chemistry, Applied
Kubra Ertan, Asli Celebioglu, Rimi Chowdhury, Gulum Sumnu, Serpil Sahin, Craig Altier, Tamer Uyar
Summary: In this study, the inclusion complexes of carvacrol with gamma-cyclodextrin were incorporated into gelatin/pullulan nanofibers to improve their stability and antimicrobial properties in food packaging systems. The inclusion complexes significantly reduced the loss of carvacrol during electrospinning and improved its storage stability. Furthermore, the inclusion complexes displayed excellent antioxidant performance in food packaging applications.
FOOD HYDROCOLLOIDS
(2023)
Article
Pharmacology & Pharmacy
Spoorthi Patil, Asli Celebioglu, Tamer Uyar
Summary: In this study, an inclusion complex nanofibrous film of isoniazid with a highly water-soluble cyclodextrin derivative was successfully prepared using electrospinning technique. The resulting nanofibrous film showed uniform fiber morphology and achieved faster release profile for isoniazid compared to its pristine powder form, making it a promising oral drug delivery system.
JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
(2023)
Article
Chemistry, Multidisciplinary
Asli Celebioglu, Christopher W. Lawson, Emmy Zhiren Hsiung, Rimi Chowdhury, Craig Altier, Tamer Uyar
Summary: The global plastic waste is increasing due to the mass production and extensive use of surgical face masks during the COVID-19 outbreak. In order to address the environmental concerns, alternative face coverings are needed. This study developed electrospun nanofibrous mats (NM) using a renewable biopolymer, pullulan, and a naturally occurring essential oil compound, trans-cinnamaldehyde (CAH), in γ-cyclodextrin inclusion complexes (γ-CD-IC). These NM can be easily inserted into cloth masks and have higher loading efficiency compared to other mats. They also demonstrated good antibacterial activity, storage stability, thermal stability, and desirable properties such as pore size and water vapor permeability.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2023)
Article
Materials Science, Multidisciplinary
Yelin Ko, Juan P. Hinestroza, Tamer Uyar
Summary: This study investigates the structural and physical properties of electrospun nanofibers produced from postconsumer poly(ethyleneterephthalate) (PET) textile sources and PET bottles. The electrospun PET nanofibers exhibited distinct cold crystallization and sharper melt-crystallization behavior, as well as improved resolution of their Fourier transform infrared spectra. The electrospun nanofibers from PET textiles and bottles may have potential applications in filtration, protective clothing, and environmental remediation.
ACS APPLIED POLYMER MATERIALS
(2023)
Article
Nanoscience & Nanotechnology
Asli Celebioglu, Tamer Uyar
Summary: This study developed nanofibrous hydrogels for wound healing using starch-derived cyclodextrin. The hydrogels showed good biocompatibility and drug release performance, making them a promising candidate for wound dressings.
ACS APPLIED BIO MATERIALS
(2023)
Article
Materials Science, Multidisciplinary
Fuat Topuz, Bhushan Patil, Tamer Uyar
Summary: This study presents a green one-pot synthesis of bimetallic nanoparticles of Pd and Pt using RNA molecules as the capping/stabilizing agent and ascorbic acid as the reducing agent. The bimetallic nanoparticles have been utilized for hydrogen evolution reactions, showing enhanced catalytic performance compared to pure Pd nanoparticles and Pd/C materials.
MATERIALS ADVANCES
(2023)
Article
Food Science & Technology
Asli Celebioglu, Deniz Tekant, Mehmet Emin Kilic, Engin Durgun, Tamer Uyar
Summary: Encapsulation of resveratrol into electrospun cyclodextrin nanofibers can create a novel fast-disintegrating delivery system. Various techniques confirmed the encapsulation and amorphization of resveratrol. The resulting nanofibrous films demonstrated rapid disintegration and enhanced antioxidant properties.
ACS FOOD SCIENCE & TECHNOLOGY
(2022)
