AMPK-SIRT1-PGC1α Signal Pathway Influences the Cognitive Function of Aged Rats in Sevoflurane-Induced Anesthesia

Obesity caused by a high-fat diet regulates the Sirt1/PGC-1α/FNDC5/BDNF pathway to exacerbate isoflurane-induced postoperative cognitive dysfunction in older mice

(2019) Zhimeng Zhao et al.   NUTRITIONAL NEUROSCIENCE

AMPKα1 overexpression improves postoperative cognitive dysfunction in aged rats through AMPK-Sirt1 and autophagy signaling

(2019) Wen-Jun Yan et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Triptolide Improves Cognitive Dysfunction in Rats with Vascular Dementia by Activating the SIRT1/PGC-1α Signaling Pathway

(2019) Peng Yao et al.   NEUROCHEMICAL RESEARCH

Berberine Improves Cognitive Deficiency and Muscular Dysfunction via Activation of the AMPK/SIRT1/PGC-1a Pathway in Skeletal Muscle from Naturally Aging Rats

(2018) Y. Yu et al.   Journal of Nutrition Health & Aging

AMPK Activation Ameliorates Alzheimer's Disease-Like Pathology and Spatial Memory Impairment in a Streptozotocin-Induced Alzheimer's Disease Model in Rats

(2018) Lai-Ling Du et al.   JOURNAL OF ALZHEIMERS DISEASE

Apoptosis and Oxidative Stress in Neurodegenerative Diseases

(2018) Elena Radi et al.   JOURNAL OF ALZHEIMERS DISEASE

Expression and function of the metabotropic purinergic P2Y receptor family in experimental seizure models and patients with drug-refractory epilepsy

(2017) Mariana Alves et al.   EPILEPSIA

Association Between ABO Blood Type and Postoperative Cognitive Dysfunction in Elderly Patients Undergoing Unilateral Total Hip Arthroplasty Surgery in China

(2017) Jie Li et al.   MEDICAL SCIENCE MONITOR

Effects of haloperidol, olanzapine, ziprasidone, and PHA-543613 on spatial learning and memory in the Morris water maze test in naïve and MK-801-treated mice

(2017) Houxu Ning et al.   Brain and Behavior

Granulosa cell and oocyte mitochondrial abnormalities in a mouse model of fragile X primary ovarian insufficiency

(2016) Carola Conca Dioguardi et al.   MOLECULAR HUMAN REPRODUCTION

Aβ25–35 Suppresses Mitochondrial Biogenesis in Primary Hippocampal Neurons

(2015) Weiguo Dong et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Minocycline Alleviates Sevoflurane-Induced Cognitive Impairment in Aged Rats

(2015) Yue Tian et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Involvement of the blood–brain barrier opening in cognitive decline in aged rats following orthopedic surgery and high concentration of sevoflurane inhalation

(2014) Nan Hu et al.   BRAIN RESEARCH

AMPK activation prevents prenatal stress-induced cognitive impairment: Modulation of mitochondrial content and oxidative stress

(2014) Ke Cao et al.   FREE RADICAL BIOLOGY AND MEDICINE

Postoperative Cognitive Function Following General Versus Regional Anesthesia

(2014) Nicholas Davis et al.   JOURNAL OF NEUROSURGICAL ANESTHESIOLOGY

A PPARγ, NF-κB and AMPK-Dependent Mechanism May Be Involved in the Beneficial Effects of Curcumin in the Diabetic db/db Mice Liver

(2014) Lizbeth Jiménez-Flores et al.   MOLECULES

Isoflurane and sevoflurane increase interleukin-6 levels through the nuclear factor-kappa B pathway in neuroglioma cells

(2013) L. Zhang et al.   BRITISH JOURNAL OF ANAESTHESIA

Redox regulation of SIRT1 in inflammation and cellular senescence

(2013) Jae-woong Hwang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Sirt1 Mediates Hyperbaric Oxygen Preconditioning-Induced Ischemic Tolerance in Rat Brain

(2013) Wenjun Yan et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Minocycline improves postoperative cognitive impairment in aged mice by inhibiting astrocytic activation

(2013) Wen-Jie Jin et al.   NEUROREPORT

Parecoxib mitigates spatial memory impairment induced by sevoflurane anesthesia in aged rats

(2012) M. GONG et al.   ACTA ANAESTHESIOLOGICA SCANDINAVICA

Resveratrol Ameliorates Aging-Related Metabolic Phenotypes by Inhibiting cAMP Phosphodiesterases

(2012) Sung-Jun Park et al.   CELL

PGC1  and mitochondrial metabolism - emerging concepts and relevance in ageing and neurodegenerative disorders

(2012) S. Austin et al.   JOURNAL OF CELL SCIENCE

Negative regulation of inflammation by SIRT1

(2012) Jun Xie et al.   PHARMACOLOGICAL RESEARCH

Regulation of SIRT1 in cellular functions: Role of polyphenols

(2010) Sangwoon Chung et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

SIRT1 Promotes Proliferation and Prevents Senescence Through Targeting LKB1 in Primary Porcine Aortic Endothelial Cells

(2010) Yi Zu et al.   CIRCULATION RESEARCH

Quercetin activates AMP-activated protein kinase by reducing PP2C expression protecting old mouse brain against high cholesterol-induced neurotoxicity

(2010) Jun Lu et al.   JOURNAL OF PATHOLOGY

Anesthesia and Postoperative Cognitive Dysfunction (POCD)

(2010) Bettina Jungwirth et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Fibroblast growth factor 21 regulates energy metabolism by activating the AMPK–SIRT1–PGC-1α pathway

(2010) Mary D. L. Chau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Long-term Consequences of Postoperative Cognitive Dysfunction

(2009) Jacob Steinmetz et al.   ANESTHESIOLOGY

The Common Inhalational Anesthetic Sevoflurane Induces Apoptosis and Increases β-Amyloid Protein Levels

(2009) Yuanlin Dong et al.   ARCHIVES OF NEUROLOGY

PGC-1α, SIRT1 and AMPK, an energy sensing network that controls energy expenditure

(2009) Carles Cantó et al.   CURRENT OPINION IN LIPIDOLOGY

Isoflurane and sevoflurane dose-dependently impair hippocampal long-term potentiation

(2009) Rainer Haseneder et al.   EUROPEAN JOURNAL OF PHARMACOLOGY