A 3D-microtissue-based phenotypic screening of radiation resistant tumor cells with synchronized chemotherapeutic treatment

3D cell culture systems modeling tumor growth determinants in cancer target discovery

(2014) Claudio R. Thoma et al.   ADVANCED DRUG DELIVERY REVIEWS

The need for complex 3D culture models to unravel novel pathways and identify accurate biomarkers in breast cancer

(2014) Britta Weigelt et al.   ADVANCED DRUG DELIVERY REVIEWS

Systematic improvement of lentivirus transduction protocols by antibody fragments fused to VSV-G as envelope glycoprotein

(2014) Ines Höfig et al.   BIOMATERIALS

A High Content Clonogenic Survival Drug Screen Identifies MEK Inhibitors as Potent Radiation Sensitizers for KRAS Mutant Non–Small-Cell Lung Cancer

(2014) Steven H. Lin et al.   Journal of Thoracic Oncology

Phenotypic screening in cancer drug discovery — past, present and future

(2014) John G. Moffat et al.   NATURE REVIEWS DRUG DISCOVERY

Phase I trials involving radiation therapy, quantifying the risks

(2013) Yaacov Richard Lawrence et al.   Journal of Medical Imaging and Radiation Oncology

A modified Phase I trial of radiation dose escalation in 3D conformal radiation therapy with concurrent vinorelbine and carboplatin chemotherapy for non-small-cell lung cancer

(2013) Q. Lin et al.   JOURNAL OF RADIATION RESEARCH

Effect of homotypic and heterotypic interaction in 3D on the E-selectin mediated adhesive properties of breast cancer cell lines

(2012) Siddarth Chandrasekaran et al.   BIOMATERIALS

Development, validation and pilot screening of an in vitro multi-cellular three-dimensional cancer spheroid assay for anti-cancer drug testing

(2012) Rati Lama et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation

(2012) Maria Vinci et al.   BMC BIOLOGY

Poloxamer synperonic F108 improves cellular transduction with lentiviral vectors

(2012) Ines Höfig et al.   JOURNAL OF GENE MEDICINE

Radiation resistance due to high expression of miR-21 and G2/M checkpoint arrest in breast cancer cells

(2012) Nataša Anastasov et al.   Radiation Oncology

G2 checkpoint abrogator abates the antagonistic interaction between antimicrotubule drugs and radiation therapy

(2012) Meihua Sui et al.   RADIOTHERAPY AND ONCOLOGY

384 hanging drop arrays give excellent Z-factors and allow versatile formation of co-culture spheroids

(2011) Amy Y. Hsiao et al.   BIOTECHNOLOGY AND BIOENGINEERING

Towards automated production and drug sensitivity testing using scaffold-free spherical tumor microtissues

(2011) Maren Drewitz et al.   Biotechnology Journal

Effects of phytochemicals on ionization radiation-mediated carcinogenesis and cancer therapy

(2011) Dhanya Nambiar et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Modeling cellular processes in 3D

(2011) Alex Mogilner et al.   TRENDS IN CELL BIOLOGY

Incorporation of multicellular spheroids into 3-D polymeric scaffolds provides an improved tumor model for screening anticancer drugs

(2010) Won Jin Ho et al.   CANCER SCIENCE

Adjuvant chemotherapy prior to postoperative concurrent chemoradiotherapy for locoregionally advanced head and neck cancer

(2010) Kevin S. Choe et al.   RADIOTHERAPY AND ONCOLOGY

C/EBP  expression in ALK-positive anaplastic large cell lymphomas is required for cell proliferation and is induced by the STAT3 signaling pathway

(2009) N. Anastasov et al.   HAEMATOLOGICA

Spheroid-based drug screen: considerations and practical approach

(2009) Juergen Friedrich et al.   Nature Protocols