AICA ‐ribosiduria due to ATIC deficiency: Delineation of the phenotype with three novel cases, and long‐term update on the first case

PAICS deficiency, a new defect of de novo purine synthesis resulting in multiple congenital anomalies and fatal outcome

(2019) Anna Pelet et al.   HUMAN MOLECULAR GENETICS

Analysis of substrate binding in individual active sites of bifunctional human ATIC

(2018) Danuta Witkowska et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Identification of ATIC as a Novel Target for Chemoradiosensitization

(2018) Xiangfei Liu et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

AICAR Prevents Acute Olanzapine-Induced Disturbances in Glucose Homeostasis

(2018) Natasha D. Bush et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

AICAR Antiproliferative Properties Involve the AMPK-Independent Activation of the Tumor Suppressors LATS 1 and 2

(2018) Chloé Philippe et al.   NEOPLASIA

Preclinical evidence of the enhanced effectiveness of combined rapamycin and AICAR in reducing kidney cancer

(2018) Sitai Liang et al.   Molecular Oncology

The influence of AICAR - direct activator of AMP-activated protein kinase (AMPK) - on liver proteome in apoE-knockout mice

(2017) Maciej Suski et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

ATIC Gene Polymorphism and Histologic Response to Chemotherapy in Pediatric Osteosarcoma

(2017) Jeong A. Park et al.   JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY

AICAR induces AMPK-independent programmed necrosis in prostate cancer cells

(2016) Feng Guo et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Association of genetic polymorphisms ofde novonucleotide biosynthesis with increased CHD susceptibility in the northern Chinese population

(2016) Y.-C. Jiang et al.   CLINICAL GENETICS

Intraosseous inflammatory myofibroblastic tumor of the mandible with a novel ATIC-ALK fusion mutation: a case report

(2016) Yoko Tateishi et al.   Diagnostic Pathology

AICAR induces mitochondrial apoptosis in human osteosarcoma cells through an AMPK-dependent pathway

(2016) Masayuki Morishita et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

ATIC missense variant affects response to methotrexate treatment in rheumatoid arthritis patients

(2016) Mateusz Kurzawski et al.   PHARMACOGENOMICS

ATIC 347C>G gene polymorphism may be associated with methotrexate-induced adverse events in south Indian Tamil rheumatoid arthritis

(2016) Niveditha Muralidharan et al.   PHARMACOGENOMICS

Association of the ATIC 347 C/G polymorphism with responsiveness to and toxicity of methotrexate in rheumatoid arthritis: a meta-analysis

(2016) Young Ho Lee et al.   RHEUMATOLOGY INTERNATIONAL

The Last Enzyme of the De Novo Purine Synthesis Pathway 5-aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase/IMP Cyclohydrolase (ATIC) Plays a Central Role in Insulin Signaling and the Golgi/Endosomes Protein Network

(2015) Martial Boutchueng-Djidjou et al.   MOLECULAR & CELLULAR PROTEOMICS

Folate-Dependent Purine Nucleotide Biosynthesis in Humans

(2015) Joseph E Baggott et al.   Advances in Nutrition

Adenylosuccinate lyase deficiency

(2014) Agnieszka Jurecka et al.   JOURNAL OF INHERITED METABOLIC DISEASE

5-Aminoimidazole-4-carboxamide ribonucleotide-transformylase and inosine-triphosphate-pyrophosphatase genes variants predict remission rate during methotrexate therapy in patients with juvenile idiopathic arthritis

(2014) Serena Pastore et al.   RHEUMATOLOGY INTERNATIONAL

Revisiting and revising the purinosome

(2013) Alice Zhao et al.   Molecular BioSystems

Acadesine for patients with relapsed/refractory chronic lymphocytic leukemia (CLL): a multicenter phase I/II study

(2012) Eric Van Den Neste et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Mutations of ATIC and ADSL affect purinosome assembly in cultured skin fibroblasts from patients with AICA-ribosiduria and ADSL deficiency

(2011) V. Baresova et al.   HUMAN MOLECULAR GENETICS

The enzymatic activity of 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase is enhanced by NPM-ALK: new insights in ALK-mediated pathogenesis and the treatment of ALCL

(2008) F. E. Boccalatte et al.   BLOOD

Reversible Compartmentalization of de Novo Purine Biosynthetic Complexes in Living Cells

(2008) S. An et al.   SCIENCE