期刊
JOURNAL OF INFECTIOUS DISEASES
卷 222, 期 8, 页码 1289-1292出版社
OXFORD UNIV PRESS INC
DOI: 10.1093/infdis/jiaa471
关键词
SARS-CoV-2; oral rinses; inactivation; suspension test; transmission
资金
- European Union [101003555]
- International Graduate School in Molecular Medicine Ulm
- Stiftung Universitatsmedizin Essen
The ongoing severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic creates a significant threat to global health. Recent studies suggested the significance of throat and salivary glands as major sites of virus replication and transmission during early coronavirus disease 2019, thus advocating application of oral antiseptics. However, the antiviral efficacy of oral rinsing solutions against SARS-CoV-2 has not been examined. Here, we evaluated the virucidal activity of different available oral rinses against SARS-CoV-2 under conditions mimicking nasopharyngeal secretions. Several formulations with significant SARS-CoV-2 inactivating properties in vitro support the idea that oral rinsing might reduce the viral load of saliva and could thus lower the transmission of SARS-CoV-2.
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