期刊
JOURNAL OF EXPERIMENTAL MEDICINE
卷 217, 期 7, 页码 -出版社
ROCKEFELLER UNIV PRESS
DOI: 10.1084/jem.20200885
关键词
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资金
- National Institutes of Health [CA163507, AR056296, AI124346, AI101935]
- American Lebanese Syrian Associated Charities
ZBP1 triggers NLRP3 inflammasome activation/pyroptosis, apoptosis, and necroptosis; the specific ligand for ZBP1 activation remains ambiguous. Recent studies, including Devos et al. in this issue of JEM (https://doi.org/10.1084/jem.20191913), collectively suggest that ZBP1 sensing Z-nucleic acids is critical for cell death/inflammatory disease.
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