Plant-Derived and Endogenous Cannabinoids in Epilepsy

Drug-drug interaction between clobazam and cannabidiol in children with refractory epilepsy

(2015) Alexandra L. Geffrey et al.   EPILEPSIA

Attenuation of kainic acid-induced status epilepticus by inhibition of endocannabinoid transport and degradation in guinea pigs

(2015) Liubov Shubina et al.   EPILEPSY RESEARCH

Cannabinoids for paediatric epilepsy: Weeding out the issues

(2015) Michelle S Lorentzos et al.   JOURNAL OF PAEDIATRICS AND CHILD HEALTH

Weeding out bad waves: towards selective cannabinoid circuit control in epilepsy

(2015) Ivan Soltesz et al.   NATURE REVIEWS NEUROSCIENCE

Cannabinoid and nitric oxide signaling interplay in the modulation of hippocampal hyperexcitability: Study on electrophysiological and behavioral models of temporal lobe epilepsy in the rat

(2015) F. Carletti et al.   NEUROSCIENCE

Cannabinoids in the Treatment of Epilepsy

(2015) Daniel Friedman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cannabis, cannabidiol, and epilepsy — From receptors to clinical response

(2014) Jerzy P. Szaflarski et al.   EPILEPSY & BEHAVIOR

Phytocannabinoids and epilepsy

(2014) R. G. dos Santos et al.   JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS

Distinct modulation of the endocannabinoid system upon kainic acid-induced in vivo seizures and in vitro epileptiform bursting

(2014) Filomena Fezza et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Endocannabinoids, Related Compounds and Their Metabolic Routes

(2014) Filomena Fezza et al.   MOLECULES

Systematic review: Efficacy and safety of medical marijuana in selected neurologic disorders: Report of the Guideline Development Subcommittee of the American Academy of Neurology

(2014) B. S. Koppel et al.   NEUROLOGY

Cannabidiol Is a Potent Inhibitor of the Catalytic Activity of Cytochrome P450 2C19

(2013) Rongrong Jiang et al.   Drug Metabolism and Pharmacokinetics

Report of a parent survey of cannabidiol-enriched cannabis use in pediatric treatment-resistant epilepsy

(2013) Brenda E. Porter et al.   EPILEPSY & BEHAVIOR

CB1 agonists, locally applied to the cortico-thalamic circuit of rats with genetic absence epilepsy, reduce epileptic manifestations

(2013) Rita Citraro et al.   EPILEPSY RESEARCH

Metabolism of endocannabinoids and relatedN-acylethanolamines: Canonical and alternative pathways

(2013) Natsuo Ueda et al.   FEBS Journal

Biochemical and pharmacological characterization of human α/β-hydrolase domain containing 6 (ABHD6) and 12 (ABHD12)

(2012) Dina Navia-Paldanius et al.   JOURNAL OF LIPID RESEARCH

Equipotent Inhibition of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase – Dual Targets of the Endocannabinoid System to Protect against Seizure Pathology

(2012) Vinogran Naidoo et al.   Neurotherapeutics

Endocannabinoid Oxygenation by Cyclooxygenases, Lipoxygenases, and Cytochromes P450: Cross-Talk between the Eicosanoid and Endocannabinoid Signaling Pathways

(2011) Carol A. Rouzer et al.   CHEMICAL REVIEWS

Potent inhibition of human cytochrome P450 3A isoforms by cannabidiol: Role of phenolic hydroxyl groups in the resorcinol moiety

(2011) Satoshi Yamaori et al.   LIFE SCIENCES

International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid Receptors and Their Ligands: Beyond CB1 and CB2

(2010) R. G. Pertwee et al.   PHARMACOLOGICAL REVIEWS

N-acylethanolamine metabolism with special reference to N-acylethanolamine-hydrolyzing acid amidase (NAAA)

(2010) Natsuo Ueda et al.   PROGRESS IN LIPID RESEARCH

Cerebrospinal fluid levels of the endocannabinoid anandamide are reduced in patients with untreated newly diagnosed temporal lobe epilepsy

(2009) Andrea Romigi et al.   EPILEPSIA

Selective CB2 Receptor Agonism Protects Central Neurons from Remote Axotomy-Induced Apoptosis through the PI3K/Akt Pathway

(2009) M. T. Viscomi et al.   JOURNAL OF NEUROSCIENCE

Evidences of cannabinoids-induced modulation of paroxysmal events in an experimental model of partial epilepsy in the rat

(2009) Valerio Rizzo et al.   NEUROSCIENCE LETTERS

Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb

(2009) Angelo A. Izzo et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

cDNA cloning and characterization of human and mouse Ca2+-independent phosphatidylethanolamine N-acyltransferases

(2008) Xing-Hua Jin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Anandamide Biosynthesis Catalyzed by the Phosphodiesterase GDE1 and Detection of Glycerophospho-N-acyl Ethanolamine Precursors in Mouse Brain

(2008) Gabriel M. Simon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY