Hypocrellin B triggered sonodynamic therapy reverses multidrug resistance of doxorubicin-resistant SGC7901/ADR cells via down-regulation of P-gp expression

Checkpoint blockade and nanosonosensitizer-augmented noninvasive sonodynamic therapy combination reduces tumour growth and metastases in mice

(2019) Wenwen Yue et al.   Nature Communications

Quantum Yield‐Engineered Biocompatible Probes Illuminate Lung Tumor Based on Viscosity Confinement‐Mediated Antiaggregation

(2019) Kun Zhang et al.   ADVANCED FUNCTIONAL MATERIALS

Extravascular gelation shrinkage-derived internal stress enables tumor starvation therapy with suppressed metastasis and recurrence

(2019) Kun Zhang et al.   Nature Communications

Cancer statistics, 2018

(2018) Rebecca L. Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Biodegradable hypocrellin derivative nanovesicle as a near-infrared light-driven theranostic for dually photoactive cancer imaging and therapy

(2018) Xiuli Zheng et al.   BIOMATERIALS

Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

(2018) Freddie Bray et al.   CA-A CANCER JOURNAL FOR CLINICIANS

The effects of ultrasound exposure on P-glycoprotein-mediated multidrug resistance in vitro and in vivo

(2018) Chixiong Huang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Thermo- and pH-dual responsive polymeric micelles with upper critical solution temperature behavior for photoacoustic imaging-guided synergistic chemo-photothermal therapy against subcutaneous and metastatic breast tumors

(2018) Zhe Yang et al.   Theranostics

Nanocomposite plasters for the treatment of superficial tumors by chemo-photothermal combination therapy

(2018) Wei Qi et al.   International Journal of Nanomedicine

Comparison of hypocrellin B-mediated sonodynamic responsiveness between sensitive and multidrug-resistant human gastric cancer cell lines

(2018) Yichen Liu et al.   Journal of Medical Ultrasonics

Current applications and future prospects of nanomaterials in tumor therapy

(2017) Yu Huang et al.   International Journal of Nanomedicine

A nanoliposome-based photoactivable drug delivery system for enhanced cancer therapy and overcoming treatment resistance

(2017) Jinjin Shi et al.   International Journal of Nanomedicine

Ultrasound-triggered release of sinoporphyrin sodium from liposome-microbubble complexes and its enhanced sonodynamic toxicity in breast cancer

(2017) Yixiang Li et al.   Nano Research

A multifunctional nanoparticle system combines sonodynamic therapy and chemotherapy to treat hepatocellular carcinoma

(2017) Yang Liu et al.   Nano Research

Micro/Nanoparticle-Augmented Sonodynamic Therapy (SDT): Breaking the Depth Shallow of Photoactivation

(2016) Xiaoqin Qian et al.   ADVANCED MATERIALS

High Levels of Expression of P-glycoprotein/Multidrug Resistance Protein Result in Resistance to Vintafolide

(2016) A. D. Guertin et al.   MOLECULAR CANCER THERAPEUTICS

Sinoporphyrin sodium triggered sono-photodynamic effects on breast cancer both in vitro and in vivo

(2016) Yichen Liu et al.   ULTRASONICS SONOCHEMISTRY

β-casein nanovehicles for oral delivery of chemotherapeutic drug combinations overcoming P-glycoprotein-mediated multidrug resistance in human gastric cancer cells

(2016) Maya Bar-Zeev et al.   Oncotarget

Localized Down-regulation of P-glycoprotein by Focused Ultrasound and Microbubbles induced Blood-Brain Barrier Disruption in Rat Brain

(2016) HongSeok Cho et al.   Scientific Reports

Resistance to cancer chemotherapy: failure in drug response from ADME to P-gp

(2015) Khalid O Alfarouk et al.   Cancer Cell International

Cargoing P-gp inhibitors via nanoparticle sensitizes tumor cells against doxorubicin

(2015) Manu Smriti Singh et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Using Hollow Carbon Nanospheres as a Light-Induced Free Radical Generator To Overcome Chemotherapy Resistance

(2015) Liming Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Rational assembly of a biointerfaced core@shell nanocomplex towards selective and highly efficient synergistic photothermal/photodynamic therapy

(2015) Chenchen Qin et al.   Nanoscale

Modulation of P-glycoprotein efflux pump: induction and activation as a therapeutic strategy

(2015) Renata Silva et al.   PHARMACOLOGY & THERAPEUTICS

Comparison of cell membrane damage induced by the therapeutic ultrasound on human breast cancer MCF-7 and MCF-7/ADR cells

(2015) Yali Jia et al.   ULTRASONICS SONOCHEMISTRY

P-glycoprotein inhibitors of natural origin as potential tumor chemo-sensitizers: A review

(2015) Hossam M. Abdallah et al.   Journal of Advanced Research

Novel Insights into Combating Cancer Chemotherapy Resistance Using a Plasmonic Nanocarrier: Enhancing Drug Sensitiveness and Accumulation Simultaneously with Localized Mild Photothermal Stimulus of Femtosecond Pulsed Laser

(2014) Liming Wang et al.   ADVANCED FUNCTIONAL MATERIALS

Sinoporphyrin sodium, a novel sensitizer, triggers mitochondrial-dependent apoptosis in ECA-109 cells via production of reactive oxygen species

(2014) Xiaobing Wang et al.   International Journal of Nanomedicine

Involvement of Mitochondrial and Reactive Oxygen Species in the Sonodynamic Toxicity of Chlorin e6 in Human Leukemia K562 Cells

(2014) Yixiang Li et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

Codelivery of an Optimal Drug/siRNA Combination Using Mesoporous Silica Nanoparticles To Overcome Drug Resistance in Breast Cancer in Vitro and in Vivo

(2013) Huan Meng et al.   ACS Nano

Efficacy of combined therapy with paclitaxel and low-level ultrasound in human chronic myelogenous leukemia cell line K562

(2013) Shuang Yang et al.   JOURNAL OF DRUG TARGETING

Reversal of Lung Cancer Multidrug Resistance by pH-Responsive Micelleplexes Mediating Co-Delivery of siRNA and Paclitaxel

(2013) Haijun Yu et al.   MACROMOLECULAR BIOSCIENCE

Mass spectrometry reveals synergistic effects of nucleotides, lipids, and drugs binding to a multidrug resistance efflux pump

(2013) J. Marcoux et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Honokiol synergizes chemotherapy drugs in multidrug resistant breast cancer cells via enhanced apoptosis and additional programmed necrotic death

(2012) WEI TIAN et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Quantitative and Site-Directed Chemical Modification of Hypocrellins toward Direct Drug Delivery and Effective Photodynamic Activity

(2012) Hong Deng et al.   JOURNAL OF MEDICINAL CHEMISTRY

Controlled Intracellular Release of Doxorubicin in Multidrug-Resistant Cancer Cells by Tuning the Shell-Pore Sizes of Mesoporous Silica Nanoparticles

(2011) Yu Gao et al.   ACS Nano

Synergistic effect of folate-mediated targeting and verapamil-mediated P-gp inhibition with paclitaxel -polymer micelles to overcome multi-drug resistance

(2011) Feihu Wang et al.   BIOMATERIALS

Hypocrellin B-mediated sonodynamic action induces apoptosis of hepatocellular carcinoma cells

(2011) Xinna Wang et al.   ULTRASONICS

Synthesis, molecular structure, and validation of metalloprobes for assessment of MDR1 P-glycoprotein-mediated functional transport

(2010) Jothilingam Sivapackiam et al.   DALTON TRANSACTIONS

Heat shock factors: integrators of cell stress, development and lifespan

(2010) Malin Åkerfelt et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Hypocrellin B Enhances Ultrasound-Induced Cell Death of Nasopharyngeal Carcinoma Cells

(2009) Ping Wang et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

Sodium arsenite induces ROS generation, DNA oxidative damage, HO-1 and c-Myc proteins, NF-κB activation and cell proliferation in human breast cancer MCF-7 cells

(2008) Ruben Ruiz-Ramos et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS