Review
Cardiac & Cardiovascular Systems
Ricardo S. Mishima, Christian V. Verdicchio, Jean Jacques Noubiap, Jonathan P. Ariyaratnam, Celine Gallagher, Dione Jones, Varun Malik, Thomas A. Agbaedeng, Melissa E. Middeldorp, Dennis H. Lau, Prashanthan Sanders, Adrian D. Elliott
Summary: This study included 15 studies with a total of 1,464,539 individuals, showing that individuals who achieved the guideline-recommended PA level had a significantly lower risk of AF. Dose-response analysis indicated that PA levels up to 1900 MET-minutes per week were associated with a lower risk of AF, but the benefit beyond that level was less clear.
Review
Cardiac & Cardiovascular Systems
Rong Zeng, Jing Wang, Ziting Liang, Jintao Zhang, Zihan Wang, Changjuan Xu, Liang Dong
Summary: This meta-analysis demonstrated that patients with atopic diseases, especially asthma, have a higher risk of developing atrial fibrillation.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Review
Cardiac & Cardiovascular Systems
Fadi Alijla, Chepkoech Buttia, Tobias Reichlin, Salman Razvi, Beatrice Minder, Matthias Wilhelm, Taulant Muka, Oscar H. Franco, Arjola Bano
Summary: This systematic review and meta-analysis found that diabetes is associated with an increased likelihood of non-paroxysmal AF rather than paroxysmal AF. Further high quality studies are needed to replicate these findings, adjust for potential confounders, elucidate mechanisms linking diabetes to non-paroxysmal AF, and assess the impact of antidiabetic medications on AF types. These strategies could eventually help decrease the risk of non-paroxysmal AF among patients with diabetes.
CARDIOVASCULAR DIABETOLOGY
(2021)
Review
Cell Biology
Yi Zheng, Nan Zhang, Yueying Wang, Feng Wang, Guangping Li, Gary Tse, Tong Liu
Summary: Leucocyte telomere shortening predicts the risk and progression of atrial fibrillation.
AGEING RESEARCH REVIEWS
(2022)
Review
Sport Sciences
William Newman, Gemma Parry--Williams, Jonathan Wiles, Jamie Edwards, Sabina Hulbert, Konstantina Kipourou, Michael Papadakis, Rajan Sharma, Jamie O'Driscoll
Summary: Athletes have a significantly higher risk of developing AF compared to non-athlete controls, particularly those participating in mixed sports and younger age groups. The mode of exercise and age are crucial factors influencing the risk of AF development.
BRITISH JOURNAL OF SPORTS MEDICINE
(2021)
Review
Cardiac & Cardiovascular Systems
Martijn J. Tilly, Sven Geurts, Angelo M. Pezzullo, Wichor M. Bramer, Natasja M. S. de Groot, Maryam Kavousi, Moniek P. M. de Maat
Summary: This study aims to summarize and analyze the evidence on the associations between coagulation factors and atrial fibrillation (AF) in both longitudinal and cross-sectional studies. The findings suggest that higher levels of coagulation factors are associated with both prevalent and incident AF, with the associations being more pronounced in cross-sectional studies. Limited evidence from longitudinal studies suggests a prothrombotic state underlying AF development.
Review
Endocrinology & Metabolism
Siyu Guo, Yuwen Huang, Xiao Liu, Jianyong Ma, Wengen Zhu
Summary: In our meta-analysis, we found that patients with type 1 diabetes mellitus (T1DM) had a higher risk of developing atrial fibrillation (AF) than the control group. Female T1DM patients had a higher incidence of AF compared to male patients. T1DM patients under the age of 65 also had an increased risk of AF compared to those over 65.
DIABETES RESEARCH AND CLINICAL PRACTICE
(2023)
Review
Cardiac & Cardiovascular Systems
Ying Liu, Yi Zheng, Gary Tse, George Bazoukis, Konstantinos Letsas, Christos Goudis, Panagiotis Korantzopoulos, Guangping Li, Tong Liu
Summary: This systematic review and meta-analysis aimed to explore the relationship between sick sinus syndrome (SSS) and atrial fibrillation (AF) and compare different therapy strategies for patients with SSS and AF. Results showed that SSS was associated with a higher risk of new-onset AF. Catheter ablation was found to be more effective than pacemaker therapy in reducing the risk of AF recurrence, AF progression, mortality, stroke, and heart failure hospitalization. Different pacing strategies for SSS were also compared, with VVI/VVIR showing a higher risk of new-onset AF compared to DDD/DDDR. AAI/AAIR had a higher risk of all-cause mortality but a lower risk of cardiac death compared to DDD/DDDR. Right atrial septum pacing showed similar risks of new-onset AF or AF recurrence compared to right atrial appendage pacing. The meta-analysis emphasized the importance of avoiding high ventricular pacing percentages in SSS patients to reduce AF burden and mortality.
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2023)
Review
Environmental Sciences
Chao Yue, Fan Yang, Fengwei Li, Yingtai Chen
Summary: This study systematically reviewed 18 studies and found that exposure to all air pollutants had a negative impact on the prevalence of atrial fibrillation in the general population. Under short-term exposure, for every 10 μg/m3 increase in PM2.5 and PM10 concentration, the OR for AF prevalence was 1.01 and 1.03, respectively. Under long-term exposure, for every 10 μg/m3 increase in PM2.5 concentration, the OR for AF prevalence was 1.07 and for PM10 was 1.03.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2021)
Review
Cardiac & Cardiovascular Systems
Peng Hu, Jun Huang, Yi Lu, Murui Zheng, Haiyi Li, Xueru Duan, Hai Deng, Wenjing Zhao, Xudong Liu
Summary: This study aimed to evaluate the association between circulating sex hormones and the risk of atrial fibrillation (AF). Through a meta-analysis of multiple cohort studies, it was found that higher endogenous dehydroepiandrosterone sulfate (DHEAS) levels in men were associated with a lower risk of AF, while total testosterone and estradiol were not associated with AF risk. Further longitudinal studies are needed to explore the relationship between various circulating sex hormones and AF risk.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Review
Cardiac & Cardiovascular Systems
Yonghui Fu, Shenghui Feng, Yingxiang Xu, Yuanjian Yang, Haibo Chen, Wenfeng He, Wengen Zhu, Kang Yin, Zhengbiao Xue, Bo Wei
Summary: This meta-analysis study found a significant association between depression, the use of antidepressants, and an increased risk of incident atrial fibrillation (AF).
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Review
Clinical Neurology
Alan Cameron, Huen Ki Cheng, Ren-Ping Lee, Daniel Doherty, Mark Hall, Pouria Khashayar, Gregory Y. H. Lip, Terence Quinn, Azmil Abdul-Rahim, Jesse Dawson
Summary: This study identified various clinical, ECG, and blood-based biomarkers associated with atrial fibrillation (AF) detection after ischemic stroke or TIA. Factors such as older age, female sex, history of heart failure, hypertension, and certain ECG parameters were found to be associated with increased likelihood of AF detection, while other factors like certain lipid concentrations were associated with reduced likelihood. These multimodal biomarkers could potentially be used to guide patient selection for cardiac monitoring after ischemic stroke/TIA, but further prospective assessments are needed to confirm their prognostic utility.
Review
Clinical Neurology
Petra Larsson, Julia Bidonde, Unni Olsen, Caryl L. Gay, Anners Lerdal, Marie Ursin, Gillian Elizabeth Mead, Elisabeth Edvardsen
Summary: In this systematic review and meta-analysis, researchers found associations between post-stroke fatigue (PSF) and reduced physical activity (PA) as well as impaired physical fitness (fitness). The results indicated that higher levels of PSF were weakly associated with impaired fitness, suggesting that fitness might play a protective role against PSF. Larger studies and randomized controlled trials are needed to confirm these findings.
INTERNATIONAL JOURNAL OF STROKE
(2023)
Review
Endocrinology & Metabolism
Ben-Gang Zhou, Sheng-Yong Ju, Yu-Zhou Mei, Xin Jiang, Meng Wang, Ai-Jing Zheng, Yan-Bing Ding
Summary: This meta-analysis aimed to explore the association between atrial fibrillation (AF) and non-alcoholic fatty liver disease (NAFLD) or metabolic-associated fatty liver disease (MAFLD). The results showed that NAFLD may be associated with a slightly higher risk of developing AF, especially among Asian populations and those diagnosed with NAFLD using FLI criteria. However, there is not enough evidence to support the proposed association between MAFLD and an increased risk of AF.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Review
Cardiac & Cardiovascular Systems
Fatima Cereja, Mariana Alves, Joaquim J. Ferreira, Daniel Caldeira
Summary: This review aimed to evaluate if patients with Parkinson's Disease (PD) are at increased risk of having atrial fibrillation (AF). The meta-analysis found no significant difference in the risk of atrial fibrillation between PD patients and controls. However, early PD showed a higher risk of AF. Overall, the current evidence does not support an increased risk of AF in PD patients, but further studies are needed to draw more conclusive results.
JOURNAL OF THROMBOSIS AND THROMBOLYSIS
(2023)
Article
Cardiac & Cardiovascular Systems
Peng Yu, Lili Hu, Jinyan Xie, Sisi Chen, Lin Huang, Zixuan Xu, Xiao Liu, Qiongqiong Zhou, Ping Yuan, Xia Yan, Jiejin Jin, Yang Shen, Wengen Zhu, Linghua Fu, Qi Chen, Jianhua Yu, Jianxin Hu, Qing Cao, Rong Wan, Kui Hong
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2018)
Review
Cardiac & Cardiovascular Systems
Linghua Fu, Wengen Zhu, Lin Huang, Jinzhu Hu, Jianyong Ma, Gregory Y. H. Lip, Kui Hong
AMERICAN JOURNAL OF CARDIOVASCULAR DRUGS
(2019)
Article
Cardiac & Cardiovascular Systems
Jiake He, Wengen Zhu, Yang Yu, Jinzhu Hu, Kui Hong
CARDIOLOGY JOURNAL
(2018)
Review
Genetics & Heredity
Chen Chen, Zhaochong Tan, Wengen Zhu, Linghua Fu, Qiling Kong, Qinmei Xiong, Jianhua Yu, Kui Hong
Review
Cardiac & Cardiovascular Systems
Yue Zhou, Jianyong Ma, Wengen Zhu
AMERICAN JOURNAL OF CARDIOVASCULAR DRUGS
(2020)
Article
Cardiac & Cardiovascular Systems
Shuai Li, Fuwei Liu, Chen Chen, Wengen Zhu, Jianyong Ma, Jinzhu Hu, Jinsong Xu, Kui Hong
INTERNATIONAL HEART JOURNAL
(2019)
Article
Cardiac & Cardiovascular Systems
Xiao Liu, Ninghong Guo, Wengen Zhu, Quan Zhou, Menglu Liu, Chen Chen, Ping Yuan, Rong Wan, Kui Hong
INTERNATIONAL HEART JOURNAL
(2019)
Review
Cardiac & Cardiovascular Systems
Yonghui Fu, Wengen Zhu, Yue Zhou, He Chen, Lan Yan, Wenfeng He
AMERICAN JOURNAL OF CARDIOVASCULAR DRUGS
(2020)
Article
Cardiac & Cardiovascular Systems
Zhengbiao Xue, Yue Zhou, Chaoyu Wu, Jie Lin, Xin Liu, Peng Yu, Wengen Zhu
HEART FAILURE REVIEWS
(2020)
Article
Cardiac & Cardiovascular Systems
Zhengbiao Xue, Yue Zhou, Chaoyu Wu, Jie Lin, Xin Liu, Wengen Zhu
HEART FAILURE REVIEWS
(2020)
Review
Medicine, General & Internal
Wenfeng He, Hao Zhang, Wengen Zhu, Zhengbiao Xue
Review
Cardiac & Cardiovascular Systems
Yunguo Zhou, Wenfeng He, Yue Zhou, Wengen Zhu
JOURNAL OF THROMBOSIS AND THROMBOLYSIS
(2020)
Article
Hematology
Wengen Zhu, Yalin Cao, Min Ye, Huiling Huang, Yuzhong Wu, Jianyong Ma, Yugang Dong, Xiao Liu, Chen Liu, Gregory Y. H. Lip
Summary: This study demonstrates that the Essen Stroke Risk Score (ESRS) has moderate discriminatory ability for predicting stroke as well as other adverse outcomes including myocardial infarction, hospitalization, and death in HFpEF patients. ESRS may have better calibration performance than other stroke scoring tools in HFpEF at high risk for stroke.
THROMBOSIS AND HAEMOSTASIS
(2023)
Article
Public, Environmental & Occupational Health
Junyi Sun, Zengshuo Xie, Yuzhong Wu, Xiao Liu, Jianyong Ma, Yugang Dong, Chen Liu, Min Ye, Wengen Zhu
Summary: This study found that moderately elevated TyG index was independently associated with a higher incidence of Alzheimer's disease.
AMERICAN JOURNAL OF PREVENTIVE MEDICINE
(2023)
Review
Multidisciplinary Sciences
Bailin Zhang, Winglam Cheng, Wulamiding Kaisaier, Zhenbang Gu, Wengen Zhu, Qiuhua Jiang
Summary: This meta-analysis found that edoxaban had lower risks of stroke or systemic embolism, major bleeding, and intracranial hemorrhage compared to other oral anticoagulants in patients with AF.
Article
Cardiac & Cardiovascular Systems
Saeed Tofighi, Hamidreza Poorhosseini, Yaser Jenab, Mohammad Alidoosti, Mohammad Sadeghian, Mehdi Mehrani, Zhale Tabrizi, Parisa Hashemi
Summary: This study aimed to predict adverse clinical outcomes in STEMI patients treated with primary PCI using machine learning models. The results showed that the DRF and GBM models had the best performance in predicting major adverse cardiovascular events.
CLINICAL CARDIOLOGY
(2024)