Article
Biochemistry & Molecular Biology
Teng-Gen Hu, Feng-Xiang Tan, Lu Li, Ke-Jing An, Bo Zou, Jing Wen, Ji-Jun Wu, Geng-Sheng Xiao, Yuan-Shan Yu, Yu-Juan Xu
Summary: Litchi polysaccharide Lzp2-2 promotes EPS production by Weissella confusa and improves the viscosity, texture, mouthfeel, and flavor of yoghurt.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Review
Food Science & Technology
Ruben Agregan, Mirian Pateiro, Benjamin M. Bohrer, Mohammad Ali Shariati, Asad Nawaz, Gholamreza Gohari, Jose M. Lorenzo
Summary: Okra, also known as Abelmoschus esculentus, is a nutritious crop that has been used in traditional medicine and functional food manufacturing. It contains various bioactive compounds that have potential health benefits, including anti-diabetic, anti-cancer, anti-hypertensive, and antimicrobial effects.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2023)
Review
Food Science & Technology
Xin Wang, Zhijun Wang, Mingyue Shen, Chen Yi, Qiang Yu, Xianxiang Chen, Jianhua Xie, Mingyong Xie
Summary: This article discusses and summarizes the synthetic methods, physicochemical properties, and biological activities of acetylated polysaccharides, with an emphasis on the structure-effect relationships introduced by acetyl groups. Research has found that acetylated polysaccharides improve physicochemical properties and biological activities, and can be used in green food materials, bioactive ingredient carriers, and functional food products.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION
(2022)
Article
Biochemistry & Molecular Biology
Chunlong Bai, Ruizhan Chen, Yu Zhang, Helong Bai, Li Tian, Hui Sun, Dongxue Li, Wenjing Wu
Summary: This study compared the physicochemical characteristics, functional properties, antioxidant and hypoglycemic activities of sweet potato stems leaves polysaccharide conjugates (SPSPCs) extracted using different techniques. The results showed that ultrasonic complex enzymes extraction (UEE) significantly increased the yield, content of uronic acid (UAC), total phenol (TPC), total flavonoid (TFC), sulfate group (SGC), water solubility (WS), glucuronic acid (GlcA), galacuronic acid (GalA), and galactose (Gal), as well as the antioxidant and hypoglycemic activities of the polysaccharide conjugates. UEE was identified as an effective extraction and modification technology for polysaccharide conjugates.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Applied
Yong Liu, Yunfang Ye, Xiaobo Hu, Junhui Wang
Summary: The polysaccharide AP1-b isolated from lignified okra consists of various sugars and exhibits significant anti-inflammatory activity by inhibiting the release of inflammatory factors. Its mechanism of action may be associated with inhibition of the NF-kappa B signaling pathway.
CARBOHYDRATE POLYMERS
(2021)
Article
Chemistry, Applied
Zhi-Ling Chen, Chun Wang, Haile Ma, Yanhong Ma, Jing-Kun Yan
Summary: This study found that ultrasound extraction at different frequencies significantly affected the extraction efficiency and properties of okra pod polysaccharides, with the OPS extracted through DFU showing better antioxidant and cholesterol absorption capacities, while the OPS extracted through SFU exhibited superior bile acid-binding capacity.
Article
Agricultural Engineering
Zhi Huang, Min-Hua Zong, Wen-Yong Lou
Summary: This study investigated the structural features and immunomodulatory activities of a polysaccharide (MSCP1) from Millettia Speciosa Champ (M. speciose). MSCP1 was found to have a high molecular weight and consist of glucose and xylose. In vitro experiments showed that MSCP1 significantly enhanced macrophage activity and increased the release of nitric oxide and cytokines, suggesting its potential as an immunomodulatory agent.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Biochemistry & Molecular Biology
Chao Li, Yue Zhang, Chuhua Zhao, Xiong Fu
Summary: This study investigated the antioxidative and immunoregulatory activities of polysaccharides extracted from Hylocereus undatus flowers. The study found that the polysaccharide fractions showed increased antioxidant activity and immunoregulatory effects in cells, suggesting their potential benefits in health promotion.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Food Science & Technology
Nailin Huo, Kashif Ameer, Zhaogen Wu, Shengnan Yan, Guihun Jiang, Karna Ramachandraiah
Summary: This study investigated the effects of phosphorylation on the composition, structure, morphology, and radical-scavenging activities of Sanchi flower polysaccharides. The introduction of phosphate groups led to the formation of pore-like structures and enhanced radical-scavenging activities. These findings are important for the potential application of Sanchi flower polysaccharides.
JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE
(2022)
Review
Biochemistry & Molecular Biology
Xue-Qing Geng, Li-Chao Pan, Hui-Qing Sun, Yuan-Yuan Ren, Zhen-Yuan Zhu
Summary: A novel acidic polysaccharide named AeP-P-1 was prepared from okra. AeP-P-1 has a high molecular weight and complex structure, and it showed potential hypolipidemic and organ-protective effects on type 2 diabetes mellitus. The mechanism of action involves the regulation of insulin/PI3K/Akt pathway proteins and promotion of glycogen synthesis.
Article
Biotechnology & Applied Microbiology
Marwa E. Atya, Xi Yang, Yuri Tashiro, Rando Tuvikene, Shingo Matsukawa
Summary: Funoran, a sulfated polysaccharide extracted from the red algal Gloiopeltis species, was obtained through two extraction strategies from Gloiopeltis furcata. The extracted funoran fractions showed varying physicochemical properties. The study also revealed that the funoran fractions exhibited shear thinning behavior in aqueous solution and the fractions obtained from strategy 2 had lower solubility, higher viscosity, and were turbid compared to those from strategy 1.
ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS
(2023)
Article
Food Science & Technology
Jingna Wu, Xiaoting Chen, Kun Qiao, Yongchang Su, Zhiyu Liu
Summary: A water-soluble polysaccharide, BFP-3, was isolated from Bangia fuscopurpurea and found to be mainly composed of rhamnose, arabinose, mannose, glucose, and galactose. It exhibited significant antitumor activity against ovarian cancer cells in vitro, indicating its potential application in ovarian cancer treatment.
FOOD SCIENCE AND HUMAN WELLNESS
(2021)
Article
Polymer Science
Zhiqiang Zhang, Li Wang, Dai Zeng, Xia Ma, Hui Wang
Summary: Lotus flower polysaccharide (LFP) and lotus seedpod polysaccharide (LSP) were separated and characterized in this study. Both polysaccharides exhibited antioxidant capacity and enhanced cellular proliferation without cytotoxicity. Furthermore, LFP and LSP were able to induce autophagy in cells.
Article
Food Science & Technology
Qian Yu, Wei Chen, Jing Zhong, Degang Qing, Chunyan Yan
Summary: Coreopsis tinctoria, commonly known as Kunlun Chrysanthemum, contains homogeneous oligosaccharides that exhibit dose-dependent effects on alpha-amylase and alpha-glucosidase inhibition, as well as NO production inhibition in BV2 cells, suggesting potential benefits for treating hyperglycemia and neuroinflammation.
FOOD AND CHEMICAL TOXICOLOGY
(2021)
Article
Chemistry, Applied
Nani Wang, Pingcui Xu, Weixuan Yao, Jiali Zhang, Shufen Liu, Yongjun Wang, Yan Zhang
Summary: PPCP-1, an arabinogalactan isolated from Phellodendron chinense Schneid., shows potential in protecting against diabetic osteoporosis through various mechanisms, making it a potential functional food or drug for bone health.
CARBOHYDRATE POLYMERS
(2021)
Article
Biochemistry & Molecular Biology
Wei-Han Hui, Yen-Lin Chen, Shu-Wei Chang
Summary: Crosslinking affects the mechanical behavior and tissue metabolism of collagen-based tissues. Aging and diabetes alter the crosslinking type and density, thus changing tissue properties. High-connectivity enzymatic crosslinking and advanced-glycation end-products result in uniform deformation under daily activity, while low-connectivity enzymatic crosslinking does not. High-connectivity model displays more sliding, while AGEs induce instability in structures near the binding sites.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yao-Bin Ma, Xiao-Qiu Zhou, Wei-Dan Jiang, Pei Wu, Yang Liu, Shu-Wei Li, Ling Tang, Lu Zhang, Hai-Feng Mi, Lin Feng
Summary: Tea polyphenols (TPs) are an inexpensive feed additive that can protect the gill function of fish against Flavobacterium columnare (F. columnare) through various mechanisms, including suppression of oxidative stress, apoptosis, and inflammation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Yan-Jia Guo, Jing-Ru Pang, Yu Zhang, Zhong-Rui Li, Xiao-Lin Zi, Hong-Min Liu, Ning Wang, Li-Juan Zhao, Ya Gao, Bo Wang, Piet Herdewijn, Cheng-Yun Jin, Ying Liu, Yi-Chao Zheng
Summary: This study identifies the conjugation of NEDD8 to LSD1 and its impact on GC cells, revealing the significance of LSD1 neddylation in GC.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Geum-Jae Jeong, Fazlurrahman Khan, Nazia Tabassum, Young-Mog Kim
Summary: Vibrio species are motile gram-negative bacteria commonly found in aquatic environments. They can adapt to environmental fluctuations and develop protective mechanisms against host immune systems. Different types of sigma and anti-sigma factors play important roles in regulating gene expression and virulence in Vibrio species.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Zahra Mohammadbagheri, Behrooz Movahedi, Shaghayegh Saeedi, Abbas Rahmati
Summary: In this study, a reusable biobased composite hydrogel was successfully synthesized and used for the removal of Tl(I) from aqueous solutions. The hydrogel exhibited high adsorption capacity and thermal stability, and the adsorption process was found to be thermodynamically spontaneous. The results demonstrated that the hydrogel can be reused multiple times without significant loss of its adsorption capacity.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Iqra Batool, Muhammad Imran, Ayesha Anwar, Farhan Ahmed Khan, Afrah E. Mohammed, Ashwag Shami, Hafiz Iqbal
Summary: Enzyme immobilization on ZnO/SnO2 and ZnO/SnO2/SA nanocomposites was studied, and the catalytic and biochemical characteristics of the immobilized enzyme were investigated. The results showed that ZnO/SnO2 and ZnO/SnO2/SA nanostructures are suitable carriers for enzyme immobilization.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Elias Mosaffa, Dhruvi Patel, Nasim Amiri Ramsheh, Rishikumar Indravadan Patel, Atanu Banerjee, Hossein Ghafuri
Summary: In this study, a unique 3D bead structure of adsorbent, composed of bacterial cellulose microfilaments reinforced chitosan adorned with melamine 2D plates, was synthesized for anionic dye removal. The adsorbent showed high specific surface area and abundant functional groups, resulting in exceptional adsorption capacity. The characteristics and optimal conditions of the adsorbent were assessed and analyzed.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Carolina Gismene, Jorge Enrique Hernandez Gonzalez, Marilia de Freitas Calmon, Andrey Fabricio Ziem Nascimento, Angela Rocio Nino Santisteban, Felipe Antunes Calil, Alana Della Torre da Silva, Paula Rahal, Rejane Maira Goes, Raghuvir Krishnaswamy Arni, Ricardo Barros Mariutti
Summary: Mammaliicoccus sciuri, a bacterium of clinical and veterinary relevance, expresses the virulence factor Exfoliative Toxin C (ExhC), which binds specifically to desmoglein-1 (Dsg1) and plays a role in tissue integrity. This study investigates the necrotic activity of ExhC and identifies a variant lacking necrotic potential but retaining enzymatic activity through mutagenesis experiments and crystal structure determination.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Bibhas K. Bhunia, Ashutosh Bandyopadhyay, Souradeep Dey, Biman B. Mandal
Summary: Intervertebral disc degeneration is a major cause of chronic low back pain and disability. Researchers have developed a bioactive silk-based hybrid hydrogel system functionalized with decellularized human Wharton's jelly extracellular matrix as bioactive cues. The hydrogels mimic the rheological and mechanical properties of the native nucleus pulposus tissue and support cell viability, proliferation, and tissue maturation.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Qun Zhang, Yonggan Yan, Zhao Li, Jing Du, Kai Zhang, Liguo Zhang, Ting Wang, Alberto Bianco, Shaohua Ge, Baojin Ma
Summary: A new crosslinking strategy has been devised to construct injectable sodium alginate hydrogels, which can be regulated for injectability and have great potential in biomedical applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Seong Eun Hong, Ji-Soo Lee, Hyeon Gyu Lee
Summary: The potential of multi-layer nanoemulsions for improving the cellular uptake, antioxidant activity, and in vitro bioaccessibility of alpha-tocopherol was examined. The results showed that the multi-layer nanoemulsions significantly enhanced the cellular uptake and antioxidant activity of alpha-tocopherol compared to free coumarin 6. Furthermore, the use of chitosan and dextran sulfate as wall materials in the multi-layer nanoemulsions led to even higher cellular uptake, in vitro bioaccessibility, and antioxidant activity of alpha-tocopherol.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jingjing Yu, Yanhui Zhang, Ruoning Zhang, Yanxiang Gao, Like Mao
Summary: High internal phase emulsions (HIPEs) based on beeswax (BW) oleogels and octenyl succinic acid starch (OSA starch) were prepared by a simple one-step method. The results showed that oleogelation improved the stability and encapsulation capability of the HIPEs, which is significant for the development of novel healthy food.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Bi-Feng Yao, Xiu-Ju Luo, Jun Peng
Summary: The balanced and continuous fission and fusion of mitochondria, regulated by OPA1, are important for maintaining mitochondrial dynamics in cardiovascular disorders. Understanding the role of OPA1 in mitochondrial fusion can provide insights into the pathogenesis of cardiovascular diseases.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Review
Biochemistry & Molecular Biology
Gokul Paramasivam, Anandhavelu Sanmugam, Vishnu Vardhan Palem, Murugan Sevanan, Ananda Babu Sairam, Nachiappan Nachiappan, Buhyun Youn, Jung Sub Lee, Muthuchamy Nallal, Kang Hyun Park
Summary: Nanomaterials are being used to deliver therapeutic agents in living systems. Different nanotechnological applications such as immunosensors, immune assays, and drug delivery are being implemented using nanotechnology. Genomics plays a crucial role in selecting appropriate drugs for personalized cancer therapy. It helps in analyzing gene and protein expression, disease classification, and designing disease models. Delivering drugs to specific areas using nanoparticles is a challenging issue.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)
Article
Biochemistry & Molecular Biology
Jing Li, Wei Wang, Han Wu, Feng Peng, Hui Gao, Ying Guan
Summary: In this study, CMH-based CPF films were prepared and their thermal and barrier properties were successfully regulated. The tensile strength and water vapor barrier property of CPF films were significantly improved, making them promising for food packaging applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2024)