Regionally encoded functional heterogeneity of astrocytes in health and disease: A perspective

Identification of region-specific astrocyte subtypes at single cell resolution

(2020) Mykhailo Y. Batiuk et al.   Nature Communications

Astrocyte layers in the mammalian cerebral cortex revealed by a single-cell in situ transcriptomic map

(2020) Omer Ali Bayraktar et al.   NATURE NEUROSCIENCE

Region-Specific Transcriptional Control of Astrocyte Function Oversees Local Circuit Activities

(2020) Anna Yu-Szu Huang et al.   NEURON

Subregional differences in astrocytes underlie selective neurodegeneration or protection in Parkinson's disease models in culture

(2019) Eric Wildon Kostuk et al.   GLIA

The Emerging Nature of Astrocyte Diversity

(2019) Baljit S. Khakh et al.   Annual Review of Neuroscience

Astrocyte alterations in neurodegenerative pathologies and their modeling in human induced pluripotent stem cell platforms

(2019) Minna Oksanen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Regionally specified human pluripotent stem cell-derived astrocytes exhibit different molecular signatures and functional properties

(2019) Robert A. Bradley et al.   DEVELOPMENT

Sonic hedgehog signaling in astrocytes mediates cell type-specific synaptic organization

(2019) Steven A Hill et al.   eLife

Questions and (some) answers on reactive astrocytes

(2019) Carole Escartin et al.   GLIA

Astrocyte molecular signatures in Huntington’s disease

(2019) Blanca Diaz-Castro et al.   Science Translational Medicine

Cortical astrocytes develop in a plastic manner at both clonal and cellular levels

(2019) Solène Clavreul et al.   Nature Communications

Kir4.1-Dependent Astrocyte-Fast Motor Neuron Interactions Are Required for Peak Strength

(2018) Kevin W. Kelley et al.   NEURON

Normal aging induces A1-like astrocyte reactivity

(2018) Laura E. Clarke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Layer-specific morphological and molecular differences in neocortical astrocytes and their dependence on neuronal layers

(2018) Darin Lanjakornsiripan et al.   Nature Communications

The Aging Astrocyte Transcriptome from Multiple Regions of the Mouse Brain

(2018) Matthew M. Boisvert et al.   Cell Reports

Molecular Architecture of the Mouse Nervous System

(2018) Amit Zeisel et al.   CELL

Intracortical astrocyte subpopulations defined by astrocyte reporter Mice in the adult brain

(2018) Lydie Morel et al.   GLIA

Cortical astroglia undergo transcriptomic dysregulation in the G93A SOD1 ALS mouse model

(2018) Sean J. Miller et al.   JOURNAL OF NEUROGENETICS

Astrocytes and Aging

(2018) Alexandra L. Palmer et al.   Frontiers in Aging Neuroscience

Reactive Astrocytes: Production, Function, and Therapeutic Potential

(2017) Shane A. Liddelow et al.   IMMUNITY

Molecular and Functional Properties of Regional Astrocytes in the Adult Brain

(2017) Lydie Morel et al.   JOURNAL OF NEUROSCIENCE

Heterogeneity in Synaptogenic Profile of Astrocytes from Different Brain Regions

(2017) Andrea Schmidt Buosi et al.   MOLECULAR NEUROBIOLOGY

Neurotoxic reactive astrocytes are induced by activated microglia

(2017) Shane A. Liddelow et al.   NATURE

Identification of diverse astrocyte populations and their malignant analogs

(2017) Chia-Ching John Lin et al.   NATURE NEUROSCIENCE

Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic, Morphological, and Functional Evidence

(2017) Hua Chai et al.   NEURON

Cell-specific and region-specific transcriptomics in the multiple sclerosis model: Focus on astrocytes

(2017) Noriko Itoh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Major Shifts in Glial Regional Identity Are a Transcriptional Hallmark of Human Brain Aging

(2017) Lilach Soreq et al.   Cell Reports

Astrocytic Insulin Signaling Couples Brain Glucose Uptake with Nutrient Availability

(2016) Cristina García-Cáceres et al.   CELL

Astroglial transcriptome dysregulation in early disease of an ALS mutant SOD1 mouse model

(2016) Sean J. Miller et al.   JOURNAL OF NEUROGENETICS

Astrocyte scar formation aids central nervous system axon regeneration

(2016) Mark A. Anderson et al.   NATURE

Purification and Characterization of Progenitor and Mature Human Astrocytes Reveals Transcriptional and Functional Differences with Mouse

(2016) Ye Zhang et al.   NEURON

Neurons diversify astrocytes in the adult brain through sonic hedgehog signaling

(2016) W. T. Farmer et al.   SCIENCE

Neural Conversion and Patterning of Human Pluripotent Stem Cells: A Developmental Perspective

(2016) Alexandra Zirra et al.   Stem Cells International

Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects

(2015) Jerome Mertens et al.   Cell Stem Cell

Circuit-specific signaling in astrocyte-neuron networks in basal ganglia pathways

(2015) R. Martin et al.   SCIENCE

Elusive roles for reactive astrocytes in neurodegenerative diseases

(2015) Lucile Ben Haim et al.   Frontiers in Cellular Neuroscience

Astrocytes in Neurodegenerative Disease: Table 1.

(2015) Hemali Phatnani et al.   Cold Spring Harbor Perspectives in Biology

Astrocyte-encoded positional cues maintain sensorimotor circuit integrity

(2014) Anna V. Molofsky et al.   NATURE

Leptin signaling in astrocytes regulates hypothalamic neuronal circuits and feeding

(2014) Jae Geun Kim et al.   NATURE NEUROSCIENCE

Impact of aging brain circuits on cognition

(2013) Rachel D. Samson et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Clonal Identity Determines Astrocyte Cortical Heterogeneity

(2012) Jorge García-Marqués et al.   CEREBRAL CORTEX

Regulated temporal-spatial astrocyte precursor cell proliferation involves BRAF signalling in mammalian spinal cord

(2012) A.-C. Tien et al.   DEVELOPMENT

Genomic Analysis of Reactive Astrogliosis

(2012) J. L. Zamanian et al.   JOURNAL OF NEUROSCIENCE

Regional Astrocyte Allocation Regulates CNS Synaptogenesis and Repair

(2012) H.-H. Tsai et al.   SCIENCE

Specification of transplantable astroglial subtypes from human pluripotent stem cells

(2011) Robert Krencik et al.   NATURE BIOTECHNOLOGY

Astrocytes Control Breathing Through pH-Dependent Release of ATP

(2010) A. V. Gourine et al.   SCIENCE

Uniquely Hominid Features of Adult Human Astrocytes

(2009) N. A. Oberheim et al.   JOURNAL OF NEUROSCIENCE

Identification of Positionally Distinct Astrocyte Subtypes whose Identities Are Specified by a Homeodomain Code

(2008) Christian Hochstim et al.   CELL

Application of a Translational Profiling Approach for the Comparative Analysis of CNS Cell Types

(2008) Joseph P. Doyle et al.   CELL