Article
Fisheries
Jian Zhang, Shuning Zhang, Xiangyi Sun, Xiudan Xu
Summary: A comparative transcriptome analysis was conducted on the spleens of turbot induced by an inactivated bivalent vaccine. The study revealed strong immune responses and the cooperation of multiple immune processes during the vaccine immunization process. The findings provide new insights into the internal mechanism of immunity in turbot.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Biology
Tingting Zhao, Aijun Ma, Shuangshuang Yang, Zhihui Huang
Summary: This study investigated the impact of heat stress on lipid metabolism in juvenile turbot by analyzing the correlations between transcriptome sequencing and metabolome sequencing data of the kidney under various high temperature conditions. Key genes and metabolites associated with lipid metabolism under heat stress were identified, providing insights into the regulation of lipid deposition and maintenance of lipid homeostasis.
JOURNAL OF THERMAL BIOLOGY
(2021)
Article
Fisheries
Jiayu Liu, Rui Shao, Yawen Lan, Xinmeng Liao, Jinjin Zhang, Kangsen Mai, Qinghui Ai, Min Wan
Summary: The study demonstrates that vitamin D-3 enhances immune responses in fish, leading to lower mortality and reduced bacterial load in infected fish. Additionally, VD3 supplementation promotes bactericidal activity and modulates immune cell responses, highlighting its potential as a defense mechanism against pathogen infection in fish.
FISH & SHELLFISH IMMUNOLOGY
(2021)
Article
Immunology
Mingzhu Pan, Jiahuan Liu, Dong Huang, Yanlin Guo, Kai Luo, Mengxi Yang, Weihua Gao, Qiaoqing Xu, Wenbing Zhang, Kangsen Mai
Summary: This study characterized the foxo3 in turbot and investigated its functions in liver inflammation through both in vitro and in vivo experiments. The results suggest that FoxO3 may modulate LPS-activated hepatic inflammation in turbot by decreasing proinflammatory cytokines, levels of liver enzymes, and activating specific pathways, providing valuable insights for immune regulation and potential therapies for liver inflammation in fish.
FRONTIERS IN IMMUNOLOGY
(2021)
Article
Fisheries
Yunji Xiu, Baoshan Guo, Jingyuan Yi, Huimin Guo, Hetron Mweemba Munang'andu, Cheng Xu, Shun Zhou
Summary: This study used RNA-seq to analyze the transcriptomic profile of kidney tissue in turbot after immunization with an inactivated bivalent vaccine against Aeromonas salmonicida and Edwardsiella tarda. The results revealed that the vaccine induced upregulation and downregulation of immune-related genes, including cytokines, complement system, and chemokines, enhancing the immune response against these pathogens in turbot.
FISH & SHELLFISH IMMUNOLOGY
(2023)
Article
Fisheries
Zhifeng Liu, Aijun Ma, Chenhao Yuan, Tingting Zhao, Haowen Chang, Jinsheng Zhang
Summary: The study analyzed the liver transcriptome of turbot in response to different salinity conditions and highlighted pathways related to energy metabolism, particularly lipid metabolism. Low salinity stress was found to inhibit lipid absorption and synthesis via the LXR alpha signaling pathway, resulting in liver lipid metabolism disorders in turbot. These findings offer new insights into the molecular mechanisms behind turbot's response to low salinity stress and breeding strategies under such conditions.
Article
Fisheries
Li'ang Yang, Lijuan Wang, Zhihao Wu, Zhiyu Hao, Zongcheng Song, Feng You, Runqing Yang
Summary: The study on genetic effects of inbreeding on growth trajectories in turbot revealed that inbreeding had a larger impact on body length compared to body weight and body width. The genetic effects were not linear with increasing inbreeding degrees and varied depending on the age of the fish. Additionally, there were low genetic correlations between growth traits in early growth days and later growth days.
Article
Biology
Zhihui Huang, Xiaoli Guo, Qingmin Wang, Aijun Ma, Tingting Zhao, Xuewei Qiao, Ming Li
Summary: This study elucidates the adaptive response of fish hearts to thermal stress, with energy metabolism playing a central role, and highlights the involvement of RNA modifications in the regulation of heat stress.
JOURNAL OF THERMAL BIOLOGY
(2022)
Article
Fisheries
Qiang Fu, Pei Zhang, Shoucong Zhao, Yuqing Li, Xingchun Li, Min Cao, Ning Yang, Chao Li
Summary: In this study, a full-length transcriptome of immune-related tissues of turbot was generated using PacBio Sequel platform. The analysis identified numerous novel gene isoforms, transcription factors, and other functional elements, providing valuable molecular resources for future research on the adaptation mechanisms and functional genomics of turbot.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Article
Fisheries
Junxia Yu, Xiaoli Liu, Ning Yang, Beibei Wang, Baofeng Su, Qiang Fu, Min Zhang, Fenghua Tan, Chao Li
Summary: TLR1 in turbot was characterized, showing wide expression in healthy tissues, strongest in spleen and head-kidney; strong responses to LPS in challenge experiments, varied responses to other pathogen-associated molecular patterns; subcellularly distributed in cytoplasm, membrane, and nucleus.
FISH & SHELLFISH IMMUNOLOGY
(2021)
Article
Fisheries
Yudong Jia, Jiawei Wang, Yuntao Gao, Bin Huang
Summary: Hypoxia stress showed sex dimorphism difference in turbot, affecting their hematological and biochemical responses, with some parameters returning to normal levels after 12 hours of reoxygenation.
Article
Fisheries
Lele Wu, Yunong Wang, Jun Li, Zongcheng Song, Shihong Xu, Changbin Song, Mingming Han, Haixia Zhao, Li Zhou, Yanfeng Wang, Xian Li, Xinlu Yue
Summary: This study investigated the influence of different LED spectra on the performance of juvenile turbot. It was found that blue spectrum resulted in the best growth performance, antioxidative activity, and pathogen resistance, while red and orange spectrum led to growth retardation and decreased antioxidative activity and pathogen resistance. Therefore, blue spectrum is recommended for rearing juvenile turbot in aquaculture systems to improve fish welfare.
Article
Fisheries
Ting Xue, Yiping Liu, Min Cao, Jie Li, Mengyu Tian, Lu Zhang, Beibei Wang, Xiaoli Liu, Chao Li
Summary: This study investigated the regulatory roles of circRNA and miRNA in the early immune response of turbot following injection of an inactivated Aeromonas salmonicida vaccine. Through high-throughput sequencing, differentially expressed circRNAs, miRNAs, and mRNAs were identified, suggesting a complex multi-molecule regulatory network involving immune-related genes. Further research is needed to fully understand the regulatory mechanisms of these circRNA-miRNA-mRNA networks in teleost immune responses.
FISH & SHELLFISH IMMUNOLOGY
(2021)
Article
Fisheries
Qiang Fu, Jie Hu, Pei Zhang, Yuqing Li, Shoucong Zhao, Min Cao, Ning Yang, Chao Li
Summary: Seventeen CC and CXC chemokine genes were identified in the turbot genome, making it a valuable resource for comparative immunological studies and functional characterization of chemokines in teleost.
FISH & SHELLFISH IMMUNOLOGY
(2022)
Article
Fisheries
Song Sun, Ding Lyu, Yulong Hu, Weiji Wang
Summary: This study aimed to determine the genetic parameters for the resistance of turbot to Edwardsiella tarda in order to design breeding protocols. The results showed consistent and high heritability estimates in the sire-dam model, indicating the successful application of selective breeding for resistance to E. tarda in the breeding population.
AQUACULTURE REPORTS
(2022)