Mechanical stretch activates piezo1 in caveolae of alveolar type I cells to trigger ATP release and paracrine stimulation of surfactant secretion from alveolar type II cells

Constitutive SRC-mediated phosphorylation of pannexin 1 at tyrosine 198 occurs at the plasma membrane

(2019) Leon J. DeLalio et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Type 2 secretory cells are primary source of ATP release in mechanically stretched lung alveolar cells

(2019) Ju Jing Tan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Interaction Between Pannexin 1 and Caveolin-1 in Smooth Muscle Can Regulate Blood Pressure

(2018) Leon J. DeLalio et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Caveolae

(2018) Robert G. Parton et al.   CURRENT BIOLOGY

Cells respond to deletion of CAV1 by increasing synthesis of extracellular matrix

(2018) C. Mendoza-Topaz et al.   PLoS One

The Hippo Pathway Regulates Caveolae Expression and Mediates Flow Response via Caveolae

(2018) Valentina Rausch et al.   CURRENT BIOLOGY

The micromechanics of lung alveoli: structure and function of surfactant and tissue components

(2018) Lars Knudsen et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Caveolin-1 Modulates Mechanotransduction Responses to Substrate Stiffness through Actin-Dependent Control of YAP

(2018) Roberto Moreno-Vicente et al.   Cell Reports

Revisiting multimodal activation and channel properties of Pannexin 1

(2017) Yu-Hsin Chiu et al.   JOURNAL OF GENERAL PHYSIOLOGY

ATP is stored in lamellar bodies to activate vesicular P2X4in an autocrine fashion upon exocytosis

(2017) Giorgio Fois et al.   JOURNAL OF GENERAL PHYSIOLOGY

Poly(benzoxazine) as an Immobilization Matrix for Miniaturized ATP and Glucose Biosensors

(2017) Charlotte Ziller et al.   ChemElectroChem

Real-time imaging of inflation-induced ATP release in the ex vivo rat lung

(2016) Kishio Furuya et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Surfactant dysfunction during overexpression of TGF-β1 precedes profibrotic lung remodeling in vivo

(2016) Elena Lopez-Rodriguez et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Caveolae: One Function or Many?

(2016) Jade P.X. Cheng et al.   TRENDS IN CELL BIOLOGY

Removal of the mechanoprotective influence of the cytoskeleton reveals PIEZO1 is gated by bilayer tension

(2016) Charles D. Cox et al.   Nature Communications

Internalized Tau sensitizes cells to stress by promoting formation and stability of stress granules

(2016) Cecilia A. Brunello et al.   Scientific Reports

ATP stimulates pannexin 1 internalization to endosomal compartments

(2015) A. K. J. Boyce et al.   BIOCHEMICAL JOURNAL

Piezo1 ion channel pore properties are dictated by C-terminal region

(2015) Bertrand Coste et al.   Nature Communications

News from the caves: update on the structure and function of caveolae

(2014) Elena Shvets et al.   CURRENT OPINION IN CELL BIOLOGY

Electrochemically induced deposition of poly(benzoxazine) precursors as immobilization matrix for enzymes

(2014) Corina Andronescu et al.   ELECTROCHEMISTRY COMMUNICATIONS

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Caveolae as plasma membrane sensors, protectors and organizers

(2013) Robert G. Parton et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A new role for P2X4 receptors as modulators of lung surfactant secretion

(2013) Pika Miklavc et al.   Frontiers in Cellular Neuroscience

Caveolin-1 Is Necessary for Hepatic Oxidative Lipid Metabolism: Evidence for Crosstalk between Caveolin-1 and Bile Acid Signaling

(2013) Manuel A. Fernández-Rojo et al.   Cell Reports

The role of caveolae in the pathophysiology of lung diseases

(2013) Michael A Thompson et al.   Expert Review of Respiratory Medicine

Spatio-temporal aspects, pathways and actions of Ca2+ in surfactant secreting pulmonary alveolar type II pneumocytes

(2012) Paul Dietl et al.   CELL CALCIUM

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Vesicular and conductive mechanisms of nucleotide release

(2012) Eduardo R. Lazarowski   Purinergic Signalling

Stressing caveolae new role in cell mechanics

(2012) Pierre Nassoy et al.   TRENDS IN CELL BIOLOGY

Interfacial sensing by alveolar type II cells: a new concept in lung physiology?

(2011) Andrea Ravasio et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Thrombin-induced ATP release from human umbilical vein endothelial cells

(2011) Stefanie Gödecke et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

What do we know about mechanical strain in lung alveoli?

(2011) Esra Roan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

An ultra fast detection method reveals strain-induced Ca2+ entry via TRPV2 in alveolar type II cells

(2011) Giorgio Fois et al.   Biomechanics and Modeling in Mechanobiology

Cells Respond to Mechanical Stress by Rapid Disassembly of Caveolae

(2011) Bidisha Sinha et al.   CELL

Pathways Regulating the Trafficking and Turnover of Pannexin1 Protein and the Role of the C-terminal Domain

(2011) Ruchi Gehi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Visualization of flow-induced ATP release and triggering of Ca2+ waves at caveolae in vascular endothelial cells

(2011) K. Yamamoto et al.   JOURNAL OF CELL SCIENCE

Caveolae respond to cell stretch and contribute to stretch-induced signaling

(2011) O. L. Gervasio et al.   JOURNAL OF CELL SCIENCE

Purinergic P2X7 receptor regulates lung surfactant secretion in a paracrine manner

(2011) A. Mishra et al.   JOURNAL OF CELL SCIENCE

The Role of Purinergic Signaling on Deformation Induced Injury and Repair Responses of Alveolar Epithelial Cells

(2011) Hewan A. Belete et al.   PLoS One

Fusion-activated Ca2+ entry via vesicular P2X4 receptors promotes fusion pore opening and exocytotic content release in pneumocytes

(2011) P. Miklavc et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human Alveolar Type II Cells Secrete and Absorb Liquid in Response to Local Nucleotide Signaling

(2010) Peter F. Bove et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pulmonary Surfactant Pathophysiology: Current Models and Open Questions

(2010) Jesús Perez-Gil et al.   PHYSIOLOGY

Fusion-Activated Ca2+ Entry: An “Active Zone” of Elevated Ca2+ during the Postfusion Stage of Lamellar Body Exocytosis in Rat Type II Pneumocytes

(2010) Pika Miklavc et al.   PLoS One

Variable stretch pattern enhances surfactant secretion in alveolar type II cells in culture

(2009) Stephen P. Arold et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Lipid rafts/caveolae as microdomains of calcium signaling

(2009) Biswaranjan Pani et al.   CELL CALCIUM

Experimental Models to Study Cell Wounding and Repair

(2009) Hewan Belete et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

A device for simultaneous live cell imaging during uni-axial mechanical strain or compression

(2009) Axel Gerstmair et al.   JOURNAL OF APPLIED PHYSIOLOGY

Thrombin Promotes Release of ATP from Lung Epithelial Cells through Coordinated Activation of Rho- and Ca2+-dependent Signaling Pathways

(2009) Lucia Seminario-Vidal et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SDPR induces membrane curvature and functions in the formation of caveolae

(2009) Carsten G. Hansen et al.   NATURE CELL BIOLOGY

Deletion of Cavin/PTRF Causes Global Loss of Caveolae, Dyslipidemia, and Glucose Intolerance

(2008) Libin Liu et al.   Cell Metabolism

Caveolae and Caveolins in the Respiratory System

(2008) Reinoud Gosens et al.   CURRENT MOLECULAR MEDICINE

Caveolin-1 alters Ca2+ signal duration through specific interaction with the G q family of G proteins

(2008) P. Sengupta et al.   JOURNAL OF CELL SCIENCE