Article
Chemistry, Multidisciplinary
Gerassimos G. Angelopoulos, Panagiotis Kanarelis, Georgia Vagdouti, Ageliki Zavlanou, Iosif Sifakakis
Summary: In this prospective study comparing fixed lingual orthodontic appliance and aligner system, it was found that the aligner group initially showed subtle injuries on the lips and cheeks, while lingual patients experienced more discomfort in swallowing and opening the mouth, with more frequent impact on consonants. However, these speech disturbances recovered within three months after appliance insertion.
APPLIED SCIENCES-BASEL
(2021)
Article
Chemistry, Multidisciplinary
Cristian Doru Olteanu, Sorana-Maria Bucur, Manuela Chibelean, Eugen Silviu Bud, Mariana Pacurar, Dana Gabriela Festila
Summary: The present study aimed to determine the intensity of pain perception in patients undergoing fixed orthodontic treatment. It was found that ring cementations were the most painful procedure, followed by arch activations, and elastic tractions were the least painful. Patients experienced the most intense pain during the first 3-4 days after procedures.
APPLIED SCIENCES-BASEL
(2022)
Review
Chemistry, Multidisciplinary
Stacy Ann Rosenberg, P. Emile Rossouw, Basir A. Barmak, Dimitrios Michelogiannakis, Fawad Javed
Summary: This systematic review assessed the postoperative facial swelling and occlusion achieved with clear aligner therapy and fixed orthodontic therapy after orthognathic surgery. Four studies showed that clear aligner therapy and fixed orthodontic therapy are comparable in terms of postoperative occlusion and facial swelling.
APPLIED SCIENCES-BASEL
(2023)
Review
Health Care Sciences & Services
Federica Di Spirito, Francesco D'Ambrosio, Davide Cannata, Vincenzo D'Anto, Francesco Giordano, Stefano Martina
Summary: This umbrella review aimed to compare the periodontal conditions of patients undergoing orthodontic treatment with clear aligners and fixed appliances. The study protocol was developed following the PRISMA statement and registered on PROSPERO. Systematic reviews with meta-analysis published in English without date restriction were searched across multiple databases. The study quality was assessed using the AMSTAR 2 tool. The findings suggest that there are slight differences in periodontal parameters between clear aligners and fixed appliances, but these differences are clinically negligible.
Article
Chemistry, Multidisciplinary
Tianjin Tao, Hengyan Liang, Xinyu Yan, Qi Fan, Qingsong Jiang, Fan Jian, Hu Long, Wenli Lai
Summary: This study compares the root parallelism in extraction cases treated with clear aligners and fixed appliances. The results show that both appliances can achieve the same root parallelism and root inclination in tooth extraction cases.
APPLIED SCIENCES-BASEL
(2022)
Article
Endocrinology & Metabolism
Niccolo Cenzato, Loris Marcolongo, Solanlly Sanchez, Cinzia Maria Norma Maspero
Summary: This study compared the oral microflora and bacterial plaque composition in patients treated with clear aligners and fixed appliances. The results showed that patients treated with clear aligners had better oral hygiene and less pathogenic composition of bacterial flora than patients treated with fixed appliances.
JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS
(2022)
Review
Engineering, Multidisciplinary
Yusong Zhang, Yujun Ning, Dongxu Liu
Summary: Currently, the predictive value of invisible orthodontic treatment outcomes is low due to the reliance on clinical experience for evaluating the orthodontic forces of clear aligners and their complex biomechanical properties. Researchers have developed various orthodontic simulation force measurement systems for clear aligners, but direct measurement of three-dimensional orthodontic forces in the intraoral environment has not yet been achieved. This study aims to review current mechanical measurement systems for clear aligners and identify solutions for measuring orthodontic forces at different locations in multidimensional space.
Article
Dentistry, Oral Surgery & Medicine
Ibtehal Almagrami, Abeer A. Almashraqi, Bushra Sufyan Almaqrami, Amin S. Mohamed, Khaled Wafaie, Maher Al-Balaa, Yiqiang Qiao
Summary: This study aimed to evaluate and compare the alveolar bone changes and investigate the prevalence and severity of orthodontically induced inflammatory root resorption (OIIRR) in patients treated with clear aligners (CA) versus conventional fixed appliances (FA). The results showed that both CA and FA treatments led to a significant reduction in alveolar bone height and root length in the maxillary incisor region, with FA treatment causing a greater extent of reduction. However, the increased OIIRR values were not clinically significant in the majority of cases in both groups.
PROGRESS IN ORTHODONTICS
(2023)
Article
Dentistry, Oral Surgery & Medicine
Amalia Cong, Antonio Carlos de Oliveira Ruellas, Sandra Khong Tai, Charlene Tai Loh, Mary Barkley, Marilia Yatabe, Marco Caminiti, Camila Massaro, Jonas Bianchi, Romain Deleat-Besson, Celia Le, Juan Carlos Prieto, Najla N. Al Turkestani, Lucia Cevidanes
Summary: This study aimed to evaluate the accuracy of tooth movements with clear aligners during presurgical orthodontics using novel 3-dimensional superimposition techniques. The results showed that the accuracy of tooth movements with clear aligners was higher than previously reported. However, clinically significant inaccuracies were found in certain cases.
AMERICAN JOURNAL OF ORTHODONTICS AND DENTOFACIAL ORTHOPEDICS
(2022)
Article
Dentistry, Oral Surgery & Medicine
Paulo Eduardo Damasceno Melo, Jessica Rico Bocato, Ana Claudia de Castro Ferreira Conti, Karen Regina Siqueira de Souza, Thais Maria Freire Fernandes, Marcio Rodrigues de Almeida, Paula Vanessa Pedron Oltramari
Summary: The study evaluated the effects of orthodontic treatment with aligners and conventional fixed appliances on speech production. Changes in speech production were observed at the start of treatment in patients with aligners, but both groups reported significant speech difficulties immediately after appliance insertion. Over time, speech production improved in both groups.
ANGLE ORTHODONTIST
(2021)
Article
Dentistry, Oral Surgery & Medicine
Bhumika Shokeen, Edward Viloria, Emily Duong, Masooma Rizvi, Guiselle Murillo, Joseph Mullen, Baochen Shi, Marcia Dinis, Huiying Li, Nini Chaichanasakul Tran, Renate Lux, Tingxi Wu
Summary: This study found that orthodontic treatment can affect the oral microbiome. Clear aligners (CAs) are more effective than fixed appliances (FAs) in improving oral hygiene. The CA tray harbors a unique plaque community.
AMERICAN JOURNAL OF ORTHODONTICS AND DENTOFACIAL ORTHOPEDICS
(2022)
Article
Dentistry, Oral Surgery & Medicine
Ziyu Guo, Ruijie Zhang, Changgang Guo, Xin Li, Zuolin Jin, Qian Liu
Summary: This study evaluated alveolar bone dimensions and their relationship with tooth movement during orthodontic treatment with fixed appliance and clear aligners. Cone beam computed tomography (CBCT) was used to measure the volume of bone defects, anterior alveolar bone thickness and height, and degree of tooth movement. The study found that alveolar bone resorption may occur due to tooth intrusion and retraction in the fixed appliance group. CBCT provides a method for three-dimensional tooth movement evaluation.
ORTHODONTICS & CRANIOFACIAL RESEARCH
(2023)
Review
Health Care Sciences & Services
Carole Charavet, Zoe Gourdain, Lea Graveline, Laurence Lupi
Summary: This article conducted a systematic review on the efficacy of different cleaning and disinfection methods for clear orthodontic aligners. The results indicate that a multi-step protocol, including the combination of mechanical and chemical methods, seems to be the most effective approach.
Review
Chemistry, Physical
Riccardo Nucera, Carolina Dolci, Angela Mirea Bellocchio, Stefania Costa, Serena Barbera, Lorenzo Rustico, Marco Farronato, Angela Militi, Marco Portelli
Summary: This systematic review compares different clear aligner therapies with regards to the presence or configuration of attachments. The analysis of several clinical trials suggests that attachments can enhance the effectiveness of clear aligner treatment, particularly in improving root torque, rotation, and mesio-distal movement. However, the evidence is limited for intrusion and extrusion, and there is a lack of studies on posterior bucco-lingual tipping/expansion.
Review
Chemistry, Physical
Gianluca M. Tartaglia, Andrea Mapelli, Cinzia Maspero, Tommaso Santaniello, Marco Serafin, Marco Farronato, Alberto Caprioglio
Summary: The recent introduction of 3D printing technology in dentistry has revolutionized the production of clear aligners, offering a more personalized and precise alternative to thermoformed ones. Direct 3D printing allows for better control of force vectors for tooth movement, resulting in increased accuracy, stability, and treatment efficacy compared to traditional aligners. Further studies are encouraged to explore the full potential of this new technology.
Article
Biology
Yue Shan, Han Han, Jingyi Zhu, Xinyu Yan, Xiaoqi Zhang, Hu Long, Fan Jian, Xiaolong Li, Yan Wang, Wenli Lai
Summary: The study demonstrated that the application of static magnetic field (SMF) can accelerate orthodontic tooth movement in mice by enhancing the rate and cumulative amount of tooth movement, increasing the width of periodontal ligament (PDL), promoting earlier formation and removal of the hyalinized zone, and increasing the number of osteoclasts.
BIOELECTROMAGNETICS
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Hong Yang, Xin Yang, He Liu, Hu Long, Huimin Hu, Qingxuan Wang, Renhuan Huang, Di Shan, Kaiming Li, Wenli Lai
Summary: This study investigated the modulation of brain activity associated with orthodontic pain by placebos using fMRI. Results showed similar brain activation patterns under placebo and non-placebo conditions, but with differences in the activation of the anterior cingulate cortex (ACC). The placebo reduced activation in the primary sensory cortex and decreased ACC activation, suggesting the fundamental role of ACC in analgesia.
Article
Clinical Neurology
Zhengyu Liao, Hu Long, Zhiping Song, Yuwei He, Wenli Lai
Summary: The mouth-wiping behavior of rats increased significantly after experimental tooth movement, showing cyclical variation. N/OFQ immunoreactivity increased in the periodontal ligament, while ppN/OFQ mRNA and protein levels in the TG were positively correlated with pain stimulus. Large fluctuations were observed in NOP gene levels.
PAIN RESEARCH & MANAGEMENT
(2021)
Article
Dentistry, Oral Surgery & Medicine
Meiya Gao, Xinyu Yan, Yanzhu Lu, Linghuan Ren, Shizhen Zhang, Xiaoqi Zhang, Qianyun Kuang, Lu Liu, Jing Zhou, Yan Wang, Wenli Lai, Hu Long
Summary: Tooth movement induces tooth mechanical hyperalgesia, which can be modulated by NGF and ASIC3. NGF-based gene therapy shows promise in alleviating tooth-movement-induced mechanical hyperalgesia.
INTERNATIONAL JOURNAL OF ORAL SCIENCE
(2021)
Article
Clinical Neurology
Rui Guo, Yiyin Chen, Lu Liu, Jing Wen, Hong Yang, Yafen Zhu, Meiya Gao, Hengyan Liang, Wenli Lai, Hu Long
Summary: NGF plays an important role in regulating orofacial pain by positively regulating CCL19 expression in the trigeminal ganglia of rats, while CCL19 increases sensitivity to experimental tooth movement orofacial pain.
FRONTIERS IN NEUROLOGY
(2021)
Article
Medicine, General & Internal
Xinyu Yan, Xiaoqi Zhang, Yiyin Chen, Hu Long, Wenli Lai
Summary: This study aimed to evaluate the association between upper lip characteristics (ULCs) and skeletal patterns (SPs) in 2079 patients. Results showed significant variations in ULCs among different SPs, with superior sulcus depth being independently associated with SPs. Adjustment for confounders revealed superior sulcus depth as the only ULC significantly corrected by intervention of skeletal growth.
Article
Dentistry, Oral Surgery & Medicine
Lu Liu, Qinxuan Song, Jing Zhou, Qianyun Kuang, Xinyu Yan, Xiaoqi Zhang, Yue Shan, Xiaolong Li, Hu Long, Wenli Lai
Summary: This study analyzed the effects of aligner overtreatment on torque control and incisor intrusion during anterior retraction. The results showed that clear aligner therapy caused lingual tipping, extrusion, and intrusion of teeth. Canine attachments enhanced these effects and required more support from posterior teeth. Appropriate overtreatment with attachments can achieve incisor intrusion and palatal root torquing.
AMERICAN JOURNAL OF ORTHODONTICS AND DENTOFACIAL ORTHOPEDICS
(2022)
Article
Cell Biology
Qingxuan Wang, Jing Xie, Chenchen Zhou, Wenli Lai
Summary: The stiffness of the substrate plays a crucial role in osteoclast differentiation and function, with higher stiffness accelerating osteoclast formation and activity. Higher stiffness substrates can also activate cytoskeletal adhesion molecules and biochemical signaling cascades.
CELL PROLIFERATION
(2022)
Review
Dentistry, Oral Surgery & Medicine
Ziwei Tang, Jiawei Zhou, Hu Long, Yanzi Gao, Qingxuan Wang, Xiaolong Li, Yan Wang, Wenli Lai, Fan Jian
Summary: This article aims to explore the mechanisms and treatments of orthodontic pain, with the hope of providing insights for future pain relief in orthodontic treatment.
JOURNAL OF ORAL REHABILITATION
(2022)
Article
Medicine, General & Internal
Shizhen Zhang, Xiaoyu Wei, Lufei Wang, Zhouqiang Wu, Lu Liu, Xinyu Yan, Wenli Lai, Hu Long
Summary: This study evaluated the bone thickness and determined the optimal sites for orthodontic mini implant insertion in the mandibular symphysis. The results showed that the bone thickness was influenced by facial types and insertion locations, heights, and angles.
Article
Neurosciences
Feifei Zhang, Fei Li, Hong Yang, Yu Jin, Wenli Lai, Graham J. Kemp, Zhiyun Jia, Qiyong Gong
Summary: This study found that brain functional networks retain small-world organization during orthodontic pain stimulation. The nodal centrality of ipsilateral brain nodes to the pain stimulus was enhanced, while the centrality of contralateral brain areas was decreased. Furthermore, anxiety mediated the relationship between nodal efficiency of the mid-cingulate cortex and pain severity.
FRONTIERS IN NEUROSCIENCE
(2022)
Article
Dentistry, Oral Surgery & Medicine
Lingling Pu, Jing Zhou, Xinyu Yan, Hong Zhou, Xian Liu, Zheng Yang, Chengge Hua, Liang Zhang, Wenli Lai, Hu Long
Summary: The orthodontic technique using a miniscrew-anchored cantilever spring proved to be effective in substituting deeply impacted third molars for second molars with severe root resorption, achieving successful treatment outcomes that satisfied the patient.
JOURNAL OF THE AMERICAN DENTAL ASSOCIATION
(2022)
Article
Dentistry, Oral Surgery & Medicine
Zhouqiang Wu, Xiaolei Gao, Hu Long, Wenli Lai
Summary: This study quantified facial asymmetry using 3D technology and compared it with evaluations by non-experts. The results showed that the chin and lateral mandible areas significantly contribute to facial symmetry, confirming the reliability of 3D technology in objectively measuring facial symmetry.
Article
Computer Science, Artificial Intelligence
Ke Zou, Tianjin Tao, Xuedong Yuan, Xiaojing Shen, Wenli Lai, Hu Long
Summary: In this study, an Interactive Dual-Branch Network (IDBNet) is proposed for automatic and accurate segmentation of the hard palate in the oral cavity. The IDBNet utilizes a dual-branch encoder-decoder, a channel map interaction module, and a guide map interaction module to effectively handle the diversity of hard palate shapes and intensity variations in different regions. Experimental results on an in-house dataset demonstrate the superior performance of the IDBNet method for hard palate segmentation.
APPLIED SOFT COMPUTING
(2022)
Article
Dentistry, Oral Surgery & Medicine
Jing Zhou, Huiyi Hong, Hong Zhou, Chengge Hua, Zheng Yang, Wenli Lai, Hu Long
Summary: The technique of orthodontic extraction with a ramus mini-screw was successfully used for the removal of deeply impacted mandibular third molars contacting the inferior alveolar nerve, avoiding nerve damage and reducing post-surgery inflammation.
QUINTESSENCE INTERNATIONAL
(2021)
