Article
Environmental Sciences
Maria Torres Toda, Demetris Avraam, Timothy James Cadman, Serena Fossati, Montserrat de Castro, Audrius Dedele, Geoffrey Donovan, Ahmed Elhakeem, Marisa Estarlich, Amanda Fernandes, Romy Goncalves, Regina Grazuleviciene, Jennifer R. Harris, Margreet W. Harskamp-van Ginkel, Barbara Heude, Jesus Ibarluzea, Carmen Iniguez, Vincent W. V. Jaddoe, Deborah Lawlor, Aitana Lertxundi, Johanna Lepeule, Rosemary McEachan, Giovenale Moirano, Johanna L. T. Nader, Anne-Marie Nybo Andersen, Marie Pedersen, Costanza Pizzi, Theano Roumeliotaki, Susana Santos, Jordi Sunyer, Tiffany Yang, Marina Vafeiadi, Tanja G. M. Vrijkotte, Mark Nieuwenhuijsen, Martine Vrijheid, Maria Foraster, Payam Dadvand
Summary: Research suggests that maternal exposure to natural environments, especially green spaces, is associated with healthy fetal growth. However, there is limited research on the effects of blue spaces. This study evaluated the associations between maternal exposure to natural environments and birth outcomes in nine European countries. The findings indicate that residential proximity to green spaces is linked to increased birth weight and reduced risk of small for gestational age (SGA). However, there is little association between accessibility to green spaces or exposure to blue spaces and birth outcomes. These findings highlight the importance of promoting natural environments, especially in deprived areas.
ENVIRONMENT INTERNATIONAL
(2022)
Article
Medicine, General & Internal
Roshan John Selvaratnam, Euan Morrison Wallace, Rory Wolfe, Peter John Anderson, Mary-Ann Davey
Summary: This study in Victoria, Australia found that iatrogenic delivery of infants with severe SGA due to suspected FGR was associated with poorer school outcomes compared with infants with severe SGA not suspected of having FGR. Iatrogenic delivery of infants with normal growth due to suspected FGR was not associated with poorer school outcomes compared with infants with normal growth not suspected of having FGR.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
(2021)
Review
Medicine, General & Internal
Ivana R. Babovic, Jelena Dotlic, Radmila Sparic, Miljana Z. Jovandaric, Mladen Andjic, Mirjana Marjanovic Cvjeticanin, Slavica Aksam, Jovan Bila, Lidija Tulic, Dusica Kocijancic Belovic, Vera Plesinac, Jovana Plesinac
Summary: In this article, the pathogenesis of gestational diabetes mellitus (GDM), its impact on fetal physiology and neonatal outcomes, as well as the usage of antenatal corticosteroid therapy (ACST) in GDM-complicated pregnancies, are reviewed. The study involved a search of MEDLINE and PubMed for relevant articles published from 1990 to 2022. The results indicate that GDM is associated with adverse pregnancy course and outcomes, affecting the fetal cardiovascular and nervous system, particularly in preterm neonates. However, the use of ACST during pregnancy should take into account the characteristics of both the mother and fetus. The conclusion suggests that GDM does not influence neonatal outcomes after the introduction of ACST, and the personalized use of ACST should consider its gestational age-specific effects on the developing fetus.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Obstetrics & Gynecology
Veronika Guenther, Ibrahim Alkatout, Christoph Vollmer, Nicolai Maass, Alexander Strauss, Manfred Voigt
Summary: The study analyzed 110,047 singleton pregnancies to investigate the interaction of maternal BMI and smoking on perinatal outcomes and birth weight. Smoking during pregnancy was significantly associated with low birth weight, highlighting the importance of advising pregnant women to quit smoking to improve newborn birth weight and reduce morbidity.
BMC PREGNANCY AND CHILDBIRTH
(2021)
Article
Multidisciplinary Sciences
Aweke A. Mitku, Temesgen Zewotir, Delia North, Prakash Jeena, Rajen N. Naidoo
Summary: This study investigated the effects of prenatal exposure factors on birth outcomes through the mediation of Favourable Fetal Growth Conditions (FFGC). The results showed that gestational weight gain and maternal pre-gestational BMI mediate the association between prenatal behavioural risk factors and FFGC.
Review
Biochemistry & Molecular Biology
Giorgia Sebastiani, Elisabet Navarro-Tapia, Laura Almeida-Toledano, Mariona Serra-Delgado, Anna Lucia Paltrinieri, Oscar Garcia-Algar, Vicente Andreu-Fernandez
Summary: Hypoxia and oxidative stress are crucial for fetal development during pregnancy, but an imbalance in oxidative molecules can lead to complications. Antioxidants may be a promising tool for treating these complications.
Article
Medicine, General & Internal
Jiao-Jiao Zou, Qian Wei, Yu-Yang Shi, Ke Wang, Yun-Hui Zhang, Hui-Jing Shi
Summary: This study analyzed data from 4574 pregnant women and their offspring, finding an association between maternal glucose levels during pregnancy and fetal intrauterine growth. Gestational diabetes or hyperglycemia were related to altered fetal growth patterns, highlighting the importance of monitoring and managing maternal glucose levels during pregnancy for optimal birth outcomes.
Article
Nutrition & Dietetics
Malgorzata Lewandowska
Summary: The study found that maternal pre-pregnancy obesity is associated with an increased risk of low birth weight, fetal growth restriction, and macrosomia in newborns. Additionally, the risk of macrosomia was three times higher for obese mothers, while the risk of low birth weight was 17 times higher, particularly in the subgroup of normal gestational weight gain. The risk profile showed that higher BMI values were associated with a higher risk of these outcomes, with specific threshold BMI values identified.
Article
Clinical Neurology
Sigal Kaplan, Mikhail Zeygarnik, Tal Stern, Kerstin Hellwig
Summary: This study assessed the impact of in utero exposure to glatiramer acetate (GA) on pregnancy and fetal outcomes. The results showed that exposure to 20 and 40 mg/mL GA in all three trimesters of pregnancy does not appear to be related to adverse pregnancy or infant outcomes.
EUROPEAN JOURNAL OF NEUROLOGY
(2023)
Review
Biochemistry & Molecular Biology
Tomasz Litwin, Jan Bembenek, Agnieszka Antos, Iwona Kurkowska-Jastrzebska, Adam Przybylkowski, Marta Skowronska, Lukasz Smolinski, Anna Czlonkowska
Summary: This study conducted a systematic review and meta-analysis on pregnancy outcomes in women with Wilson's disease. The results showed that anti-copper treatment was the main factor leading to successful pregnancies, and untreated patients were more prone to spontaneous abortions.
Article
Nutrition & Dietetics
Tatiana Papazian, Pascale Salameh, Georges Abi Tayeh, Assaad Kesrouani, Carla Aoun, Mia Abou Diwan, Lydia Rabbaa Khabbaz
Summary: This study aimed to identify the dietary patterns of Lebanese pregnant women and their correlation with maternal and neonatal outcomes. Three dietary patterns were identified: Westernized, Mixed, and Neo-Mediterranean. These patterns were found to be correlated with pre-gestational BMI and some maternal variables, but not with maternal and neonatal outcomes.
FRONTIERS IN NUTRITION
(2022)
Article
Nutrition & Dietetics
Rama J. Wahab, Vincent W. V. Jaddoe, Romy Gaillard
Summary: The study found that higher maternal early-pregnancy dietary glycemic index is associated with childhood obesity and visceral fat accumulation at age 10 among offspring of overweight or obese women. No associations were observed between dietary glycemic index and offspring adiposity among normal weight women and their children.
CLINICAL NUTRITION
(2021)
Article
Nutrition & Dietetics
Alba Yuste Gomez, Maria del Pilar Ramos Alvarez, Jose Luis Bartha
Summary: This study found a relationship between dietary and lifestyle habits at the beginning of pregnancy and the later diagnosis of GDM.
Article
Endocrinology & Metabolism
Claire L. Meek, Diana Tundidor, Denice S. Feig, Jennifer M. Yamamoto, Eleanor M. Scott, Diane D. Ma, Jose A. Halperin, Helen R. Murphy, Rosa Corcoy
Summary: This study found that HbA(1c), CGM metrics, and alternative biochemical markers were all predictive of obstetric and neonatal outcomes in pregnant women with type 1 diabetes. CGM metrics were more associated with outcomes in the first trimester, while laboratory markers were more associated with outcomes in the third trimester. Time in range (TIR) and time above range (TAR) were the most consistently predictive CGM metrics, and HbA(1c) was also a consistent predictor of suboptimal pregnancy outcomes.
Article
Genetics & Heredity
Thorhildur Juliusdottir, Valgerdur Steinthorsdottir, Lilja Stefansdottir, Gardar Sveinbjornsson, Erna Ivarsdottir, Rosa B. Thorolfsdottir, Jon K. Sigurdsson, Vinicius Tragante, Kristjan E. Hjorleifsson, Anna Helgadottir, Michael L. Frigge, Gudmundur Thorgeirsson, Rafn Benediktsson, Emil L. Sigurdsson, David O. Arnar, Thora Steingrimsdottir, Ingileif Jonsdottir, Hilma Holm, Daniel F. Gudbjartsson, Gudmar Thorleifsson, Unnur Thorsteinsdottir, Kari Stefansson
Summary: The study revealed that maternal and fetal genomes influence fetal birth weight through different mechanisms. Birth weight, as a common measure of fetal growth, is affected by both fetal and maternal genomes.