Article
Cell Biology
Meng-Hao Pan, Yu-Ke Wu, Bi-Yun Liao, Hui Zhang, Chan Li, Jun-Li Wang, Lin-Lin Hu, Baohua Ma
Summary: The study showed that different concentrations of BPA can be toxic to the organelles of mouse oocytes, leading to mitochondrial dysfunction, abnormal distribution of the endoplasmic reticulum, and abnormal structure of the Golgi apparatus. The exposure to BPA also resulted in damage to lysosomes, indicating a negative impact on the normal function of the organelles.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Cell Biology
Ping-Shuang Lu, Lan-Ping Xie, Xiao-Han Kong, Yi Xu, Shao-Chen Sun
Summary: In this study, exposure to POD significantly reduced the developmental competence of mouse oocytes, affecting the distribution and function of organelles such as endoplasmic reticulum and Golgi apparatus. This exposure induced vesicle-based protein transport disorder and aberrant accumulation of lysosomes, as well as disruption of the perinuclear distribution of mitochondria.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Cell Biology
Chao-Ying Zhao, Lin-Lin Hu, Chun-Hua Xing, Xiang Lu, Shao-Chen Sun, Yu-Xia Wei, Yan-Ping Ren
Summary: Acrylamide exposure disrupts the distribution and functions of organelles in mouse oocytes, leading to reduced developmental competence.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2022)
Article
Multidisciplinary Sciences
Yan-Zhe Zhang, Qian-Han Zhao, Hong-Wei Duan, Yuan-Jing Zou, Shao-Chen Sun, Lin-Lin Hu
Summary: Our study found that exposure to AFB1 had toxic effects on the distribution of mouse oocyte organelles, leading to a decline in oocyte quality.
Article
Biochemistry & Molecular Biology
Miguel Alpalha, David Botequim, Joao Ferreira, Rene Santus, Paulo Filipe
Summary: Vemurafenib (VB), a BRAF inhibitor used for melanoma, has strong phototoxicity to normal skin cells. Low concentrations of VB can sensitize skin cells to low doses of UVA, leading to decreased cell viability. This phototoxicity is caused by reactive oxygen species (ROS), which result in peroxidation of cellular lipids. In vivo experiments show that UVA-induced VB-photosensitization damages the plasma membrane, mitochondria, endoplasmic reticulum, lysosomes, and actin filaments, leading to mitochondrial impairment, caspase 3/7 activation, and apoptosis.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
(2023)
Review
Cell Biology
Giovanna Carra, Lidia Avalle, Laura Secli, Mara Brancaccio, Alessandro Morotti
Summary: NF-kappa B is not only a transcription factor regulating gene expression within the nucleus, but also has functions within cellular organelles. The crosstalk between NF-kappa B and cellular organelles is significant for anticancer therapies.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2022)
Review
Cell Biology
Aybars Koc, Nico De Storme
Summary: This article outlines the dynamics and inheritance of organelles during plant meiosis and discusses their functional role in the structural and molecular regulation of meiotic cell division, including key processes such as cell polarity, spindle positioning, chromosome segregation, and cell division.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2022)
Review
Cell Biology
Jeongha Kim, Sungmin Lee, Hyunwoo Kim, Haksoo Lee, Ki Moon Seong, HyeSook Youn, BuHyun Youn
Summary: Autophagy is crucial for maintaining cellular homeostasis through degrading cargo proteins and malfunctioning organelles. It is activated in response to cellular stresses like nutrient deprivation and DNA damage to reduce damage and restore homeostasis. Involvement of autophagy in repair and elimination of DNA aberrations is essential for cell survival, with autophagy playing a key role in removing impaired organelles caused by DNA damaging agents.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY
(2021)
Article
Environmental Sciences
Yi-Lin Huang, Wen-Lin Pan, Wen-Wu Cai, Jia-Qian Ju, Shao-Chen Sun
Summary: This study indicates that citrinin has adverse effects on early embryo development through inducing DNA damage, autophagy, and disrupting mitochondria function.
ENVIRONMENTAL TOXICOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Deepmala Singh, Deeksha Rajput, Sriram Kanvah
Summary: Advances in organic fluorescent probes and fluorescence imaging techniques have enhanced our understanding of cell biology, particularly in the imaging and function of the endoplasmic reticulum (ER). Organic fluorophores, with their specific functional groups and sites introduced, offer valuable tools for precise staining and dual-function imaging of ER and specific analytes.
CHEMICAL COMMUNICATIONS
(2022)
Article
Physiology
Jing Zhang, Feng Zhang, Yanou Wang
Summary: Diabetic cardiomyopathy is associated with mitochondrial damage, specifically due to increased mitochondria-endoplasmic reticulum (ER) contact. Hyperglycemia induces this contact in cardiomyocytes, but silencing of Mfn2 can protect against mitochondrial dysfunction, calcium overload, apoptosis, and ER stress, enhancing cardiomyocyte survival under high-glucose conditions.
FRONTIERS IN PHYSIOLOGY
(2021)
Article
Multidisciplinary Sciences
Katelyn C. Cook, Elene Tsopurashvili, Jason M. Needham, Sunnie R. Thompson, Ileana M. Cristea
Summary: This study designed a targeted proteomics platform to measure MCS proteins at all organelles simultaneously. Through studying the human cytomegalovirus (HCMV) infection, functional virus-driven alterations of MCS were discovered. Comparisons with other virus infections revealed the importance of contact regulation between organelles for virus replication.
NATURE COMMUNICATIONS
(2022)
Review
Biochemistry & Molecular Biology
Shuvadeep Maity, Pragya Komal, Vaishali Kumar, Anshika Saxena, Ayesha Tungekar, Vaani Chandrasekar
Summary: Accumulation of misfolded proteins is common in neurodegenerative diseases, particularly those caused by abnormal PolyQ expansions. The disruption of protein homeostasis in the endoplasmic reticulum (ER) and activation of the unfolded protein response (UPR) pathway are linked to the development of Huntington's disease (HD). Furthermore, proteins at ER-mitochondria contact sites (MAMs) play a significant role in HD progression. This review provides updated information on UPR pathways and their involvement in HD, as well as the role of MAMs in disease progression. Therapeutic interventions focusing on ER stress response proteins and ER-mitochondrial contact proteins are discussed.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Review
Genetics & Heredity
Xin Kang, Jing Wang, Liying Yan
Summary: The storage and release of calcium ions in oocyte maturation and fertilization are important functions of the endoplasmic reticulum (ER). The ER, composed of rough ER, smooth ER, and nuclear envelope, plays a crucial role in protein synthesis, transport and folding, and lipid and steroid synthesis. This review summarizes the functions, structures, interactions with other organelles, and spatiotemporal localization of the ER in mammalian oocytes. It also discusses the mechanisms of maintaining ER homeostasis and its relevance to assisted reproductive technology (ART) research.
JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
(2023)
Article
Cell Biology
Yue Xue, Tie-Gang Meng, Ying-Chun Ouyang, Sai-Li Liu, Jia-Ni Guo, Zhen-Bo Wang, Heide Schatten, Chun-Ying Song, Xing-Ping Guo, Qing-Yuan Sun
Summary: This study found that Miro1 plays a crucial role in the maturation process of mouse oocytes by regulating mitochondrial homeostasis.
JOURNAL OF CELLULAR PHYSIOLOGY
(2022)
Article
Environmental Sciences
Muqiu Hu, Xin Zhao, Jinghan Gu, Lulu Qian, Zhiqing Wang, Yuanyuan Nie, Xiaoyu Han, Long An, Haiqiang Jiang
Summary: Due to its simple process, environmental friendliness, and low operating costs, biometallurgy has become a popular technology for metals recovering from low-grade ores and tailings. An optimized agar was used to isolate and grow functional bacteria, resulting in the successful isolation of six functional stains. These strains were further tested for their ability to leach metals from polymetallic sulfide tailings, with significant improvements observed when the strains were mixed together. The selection of leaching process should be based on tailings composition and target metals.
ENVIRONMENTAL RESEARCH
(2024)
Review
Environmental Sciences
Saqib Hassan, Aswin Thacharodi, Anshu Priya, R. Meenatchi, Thanushree A. Hegde, R. Thangamani, Ht Nguyen, Arivalagan Pugazhendhi
Summary: An Endocrine Disrupting Chemical (EDC) is a compound that disrupts the function of the endocrine system and is found in the environment. EDCs, such as Bisphenol A and pesticides, have been shown to have negative effects on the female reproductive system. Understanding the relationship between EDCs and women's health is crucial for developing strategies to protect reproductive health and informing public policy decisions.
ENVIRONMENTAL RESEARCH
(2024)
Article
Environmental Sciences
Lichang Zhou, Zhaoling Li, Boyi Cheng, Jinqi Jiang, Xinqi Bi, Zongping Wang, Guanghao Chen, Gang Guo
Summary: Thiosulfate can promote sulfur-mediated bacterial activity, inhibit glycogen accumulating organisms, and enhance denitrification efficiency. After the carbon source is reduced, the competitive ability of glycogen accumulating organisms increases, resulting in reduced sulfate reduction.
ENVIRONMENTAL RESEARCH
(2024)
Article
Environmental Sciences
Claire E. Campbell, Devyn L. Cotter, Katherine L. Bottenhorn, Elisabeth Burnor, Hedyeh Ahmadi, W. James Gauderman, Carlos Cardenas-Iniguez, Daniel Hackman, Rob McConnell, Kiros Berhane, Joel Schwartz, Jiu-Chiuan Chen, Megan M. Herting
Summary: Recent studies have found a connection between air pollution and increased risk for behavioral problems during development. However, more longitudinal studies are needed to investigate how exposure during the transition to adolescence may affect emotional behaviors.
ENVIRONMENTAL RESEARCH
(2024)
Article
Environmental Sciences
Jing-hong Liang, Ru-yu Yang, Mei-ling Liu, Ying-qi Pu, Wen-wen Bao, Yu Zhao, Li-xin Hu, Yu-shan Zhang, Shan Huang, Nan Jiang, Xue-ya Pu, Shao-yi Huang, Guang-hui Dong, Ya-jun Chen
Summary: This study examines the association between urban Green and blue spaces (GBS) exposure and Emotion and behavior problems (EBP) in youth populations. The findings suggest that higher exposure to GBS, particularly green spaces (GS) and blue spaces (BS), is associated with a decrease in the risk of developing total difficulties in young individuals. The joint effect of GS and BS may also contribute to the decrease in EBPs.
ENVIRONMENTAL RESEARCH
(2024)
Article
Environmental Sciences
Diego Ruiz-Sobremazas, Mario Ruiz Coca, Miguel Morales-Navas, Rocio Rodulfo-Cardenas, Caridad Lopez-Granero, Maria Teresa Colomina, Cristian Perez-Fernandez, Fernando Sanchez-Santed
Summary: Air pollution is associated with a range of health issues and gestational exposure to environmental pollutants may be linked to neurodevelopmental disorders. This study investigated the effects of oral gestational exposure to particulate matter (PM) on ultrasonic vocalizations (USV). The findings suggest that this exposure may lead to social deficits and abnormal gene expression related to neurotransmitter systems. Further research is needed to better understand the effects of air pollution on neurodevelopmental disorders and the neurotransmission systems involved.
ENVIRONMENTAL RESEARCH
(2024)
Article
Environmental Sciences
Yagmur Kabakci, Sadiye Kosar, Ozgur Dogan, Fehmi Gorkem Uctug, Osman Atilla Arikan
Summary: This study investigated the effect of electrohydrolysis pretreatment on municipal solid waste. The results showed that applying electrohydrolysis pretreatment increased methane production and reduced the time required for hydrolysis, suggesting it is a promising method to improve anaerobic digestion efficiency.
ENVIRONMENTAL RESEARCH
(2024)
Article
Environmental Sciences
Chuanwu Zhao, Yaozhong Pan, Hanyi Wu, Yu Zhu
Summary: This study analyzed the impact of industrial zones on urban heat islands using remote sensing images and a novel spectral index. The research found that the contraction or expansion of industrial zones has a significant effect on land surface temperature. The results are valuable for environmental assessment and fine management of industrial cities.
ENVIRONMENTAL RESEARCH
(2024)
Article
Environmental Sciences
Bang Du, Zhongzhong Wang, Piet N. L. Lens, Xinmin Zhan, Guangxue Wu
Summary: This study investigated the performance, syntrophic relationships, microbial communities, and metabolic pathways of ethanol-fed reactors with different operational modes and solids retention times. The results showed that different microorganisms were enriched under different SRT conditions, and syntrophic bacteria related to methane production could be enriched under low SRT conditions.
ENVIRONMENTAL RESEARCH
(2024)
Article
Environmental Sciences
Gokulan Ravindiran, Sivarethinamohan Rajamanickam, Muralikrishnan Ramalingam, Gasim Hayder, Balamurugan Karupaiya Sathaiah, Madhava Krishna Reddy Gaddam, Senthil Kumar Muniasamy, Priya Arunkumar
Summary: The present study investigated the sustainable approach for wastewater treatment using waste algal blooms. The biochar produced by the marine algae Ulva reticulata was used to remove chromium, nickel, and zinc from aqueous solutions. The study examined the adsorbents' properties and stability using SEM/EDX, FTIR, and XRD. The results showed that the biochar had high removal efficiency for the toxic metals, and the packed bed column effectively removed the heavy metal ions. The Thomas and Adams-Bohart models were found to best fit the regression values, and desorption studies were conducted to understand the sorption and elution processes.
ENVIRONMENTAL RESEARCH
(2024)
Review
Environmental Sciences
Vignesh Vinayagam, Kavitha Nagarasampatti Palani, Sudha Ganesh, Siddharth Rajesh, Vedha Varshini Akula, Ramapriyan Avoodaiappan, Omkar Singh Kushwaha, Arivalagan Pugazhendhi
Summary: The presence of pollutants in water contributes to global pollution and poses significant threats to humans and wildlife. Finding effective wastewater treatment techniques is crucial for reducing pollutant accumulation in the environment. This paper highlights recent advances in the electrochemical advanced oxidation method and other processes for treating pharmaceuticals, dyes, and pesticide-polluted effluents.
ENVIRONMENTAL RESEARCH
(2024)
Article
Environmental Sciences
M. M. M. Ahmed, Kai-Yue Chen, Fang-Yu Tsao, Yi-Cheng Hsieh, Yu-Ting Liu, Min Tzou
Summary: This study investigated the sorption of citric acid onto humic acid-iron hydr(o)xide coprecipitate (HAFHCP) and the reciprocal effects of citric acid and P sorption on HAFHCP. The results showed that citric acid could increase P availability and have an impact on P sorption.
ENVIRONMENTAL RESEARCH
(2024)
Article
Environmental Sciences
Xibo Xu, Zeqiang Wang, Xiaoning Song, Wenjie Zhan, Shuting Yang
Summary: The selection of predictor variables is crucial in building a digital mapping model for potentially toxic elements (PTEs) in soil. Traditionally, spatial and spectral parameters have been used as predictor variables, but the temporal dimension is often overlooked. This study demonstrates the value of incorporating temporal indices in the model, leading to significant performance improvements. The temporal-spatial-spectral covariate combinations used in a random forest (RF) algorithm achieve satisfactory mapping accuracy and outperform other methods.
ENVIRONMENTAL RESEARCH
(2024)
Article
Environmental Sciences
Yan Pei, Xun Liu, Mengbo Cao, Zijun Wang, Hongbing Yang
Summary: Heteroatom doping can reconfigure the electronic structure of heterogeneous catalysts, leading to the development of advanced oxidation water purification materials with superior performance and stability. In this study, a series of catalysts with different elemental doping were prepared using a simple and environmentally friendly method. The S-doped NiCo2O4 catalyst showed excellent catalytic performance for the removal of Tetracycline, with significantly increased kinetic constant and high oxidation and mineralization efficiency in a wide pH range. The degradation process was dominated by non-radical oxidation pathway after S doping, and the overall process moved towards low toxicity.
ENVIRONMENTAL RESEARCH
(2024)
Article
Environmental Sciences
Srivalli Thimmarayan, Harshavardhan Mohan, Gaddapara Manasa, Karthi Natesan, Shanmugam Mahendran, Pavithra Muthukumar Sathya, Byung-Taek Oh, R. Ravi Kumar, Rangasamy Sigamani Gandhimathi, Arul Jayaprakash, Kamala-Kannan Seralathan
Summary: This study investigated the bacterial degradation of naphthalene (NPT) isolated from crude oil-contaminated soil. Bacillus sp. GN 3.4, a potential bacteria for NPT biodegradation, was isolated and the optimal conditions for NPT degradation were determined. The study suggests that Bacillus sp. GN 3.4 could potentially aid in bioremediation by eliminating NPT from the soil.
ENVIRONMENTAL RESEARCH
(2024)