Celastrol ameliorates cytokine toxicity and pro-inflammatory immune responses by suppressing NF-κB activation in RINm5F beta cells

Salicortin suppresses lipopolysaccharide-stimulated inflammatory responses via blockade of NF-κB and JNK activation in RAW 264.7 macrophages

(2014) Dong-Joo Kwon et al.   BMB Reports

Egr-1 regulates the transcription of the BRCA1 gene by etoposide

(2013) Soon Young Shin et al.   BMB Reports

Curcumin ameliorates TNF-α-induced ICAM-1 expression and subsequent THP-1 adhesiveness via the induction of heme oxygenase-1 in the HaCaT cells

(2013) Gi Soo Youn et al.   BMB Reports

CD83 expression induced by CpG-DNA stimulation in a macrophage cell line RAW 264.7

(2013) Min Chul Park et al.   BMB Reports

Celastrol, an NF-κB Inhibitor, Improves Insulin Resistance and Attenuates Renal Injury in db/db Mice

(2013) Jung Eun Kim et al.   PLoS One

Testing Agents for Prevention or Reversal of Type 1 Diabetes in Rodents

(2013) Christian W. Grant et al.   PLoS One

Expression and Regulation of Chemokines in Murine and Human Type 1 Diabetes

(2011) S. A. Sarkar et al.   DIABETES

Molecular targets of celastrol derived from Thunder of God Vine: Potential role in the treatment of inflammatory disorders and cancer

(2010) Radhamani Kannaiyan et al.   CANCER LETTERS

Palmitate induces a pro-inflammatory response in human pancreatic islets that mimics CCL2 expression by beta cells in type 2 diabetes

(2010) M. Igoillo-Esteve et al.   DIABETOLOGIA

The role of inflammation in insulitis and β-cell loss in type 1 diabetes

(2009) Décio L. Eizirik et al.   Nature Reviews Endocrinology

Mediators and mechanisms of pancreatic beta-cell death in type 1 diabetes

(2008) Pierre Pirot et al.   Arquivos Brasileiros de Endocrinologia e Metabologia

Cytokine-induced β-cell apoptosis is NO-dependent, mitochondria-mediated and inhibited by BCL-XL

(2008) C. Holohan et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE