ANGPTL 4 exacerbates pancreatitis by augmenting acinar cell injury through upregulation of C5a

Tibet kefir milk decreases fat deposition by regulating the gut microbiota and gene expression of Lpl and Angptl4 in high fat diet-fed rats

(2019) Jie Gao et al.   FOOD RESEARCH INTERNATIONAL

Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1 and angiopoietin-like protein 4 are associated with the increase of lipoprotein lipase activity in epicardial adipose tissue from diabetic patients

(2019) Magalí Barchuk et al.   ATHEROSCLEROSIS

Knockdown of ANGPTL-4 inhibits inflammatory response and extracellular matrix accumulation in glomerular mesangial cells cultured under high glucose condition

(2019) Linfang Qin et al.   Artificial Cells Nanomedicine and Biotechnology

ANGPTL4 Induces TMZ Resistance of Glioblastoma by Promoting Cancer Stemness Enrichment via the EGFR/AKT/4E-BP1 Cascade

(2019) Yu-Ting Tsai et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

HDL-apoA-I induces the expression of angiopoietin like 4 (ANGPTL4) in endothelial cells via a PI3K/AKT/FOXO1 signaling pathway

(2018) Dimitris Theofilatos et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Obesity: ANGPTL4 — the link binding obesity and glucose intolerance

(2018) Alan Morris   Nature Reviews Endocrinology

Trans-10, Cis-12 Conjugated Linoleic Acid Antagonizes Ligand-Dependent PPARγ Activity in Primary Cultures of Human Adipocytes

(2018) Arion Kennedy et al.   JOURNAL OF NUTRITION

Angiopoietin-like 4 Mediates Colonic Inflammation by Regulating Chemokine Transcript Stability via Tristetraprolin

(2017) Terri Phua et al.   Scientific Reports

Complement Component 5 Mediates Development of Fibrosis, via Activation of Stellate Cells, in 2 Mouse Models of Chronic Pancreatitis

(2015) Matthias Sendler et al.   GASTROENTEROLOGY

Silencing Angiopoietin-Like Protein 4 (ANGPTL4) Protects Against Lipopolysaccharide-Induced Acute Lung Injury Via Regulating SIRT1 /NF-kB Pathway

(2015) Liang Guo et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Angptl4 is upregulated under inflammatory conditions in the bone marrow of mice, expands myeloid progenitors, and accelerates reconstitution of platelets after myelosuppressive therapy

(2015) Anne Schumacher et al.   Journal of Hematology & Oncology

Angiopoietin-like 4 Increases Pulmonary Tissue Leakiness and Damage during Influenza Pneumonia

(2015) Liang Li et al.   Cell Reports

Role of C5a-C5aR axis in the development of atherosclerosis

(2014) GuiPeng An et al.   Science China-Life Sciences

Oxidative stress and inflammatory signaling in cerulein pancreatitis

(2014) Ji Hoon Yu   WORLD JOURNAL OF GASTROENTEROLOGY

Macrophage-secreted cytokines drive pancreatic acinar-to-ductal metaplasia through NF-κB and MMPs

(2013) Geou-Yarh Liou et al.   JOURNAL OF CELL BIOLOGY

Overview of Complement Activation and Regulation

(2013) Marina Noris et al.   SEMINARS IN NEPHROLOGY

New insights for C5a and C5a receptors in sepsis

(2012) Chunguang Yan et al.   Frontiers in Immunology

Regulation of triglyceride metabolism by Angiopoietin-like proteins

(2011) Frits Mattijssen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Angiopoietin-like 4 Protein Elevates the Prosurvival Intracellular O2−:H2O2 Ratio and Confers Anoikis Resistance to Tumors

(2011) Pengcheng Zhu et al.   CANCER CELL

Protection Against Myocardial Infarction and No-Reflow Through Preservation of Vascular Integrity by Angiopoietin-Like 4

(2011) Ariane Galaup et al.   CIRCULATION

TNF-α-dependent Regulation of Acute Pancreatitis Severity by Ly-6ChiMonocytes in Mice

(2011) George Perides et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The acute phase response stimulates the expression of angiopoietin like protein 4

(2010) Biao Lu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Angptl4 Protects against Severe Proinflammatory Effects of Saturated Fat by Inhibiting Fatty Acid Uptake into Mesenteric Lymph Node Macrophages

(2010) Laeticia Lichtenstein et al.   Cell Metabolism

Angiopoietin-like 4 Interacts with Matrix Proteins to Modulate Wound Healing

(2010) Yan Yih Goh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Complement: a key system for immune surveillance and homeostasis

(2010) Daniel Ricklin et al.   NATURE IMMUNOLOGY

Activating Peroxisome Proliferator-Activated Receptor   Mutant Promotes Tumor Growth In vivo by Enhancing Angiogenesis

(2009) L. Tian et al.   CANCER RESEARCH

The Acinar Cell and Early Pancreatitis Responses

(2009) Fred S. Gorelick et al.   Clinical Gastroenterology and Hepatology

New Insights Into the Mechanisms of Pancreatitis

(2009) Herbert Y. Gaisano et al.   GASTROENTEROLOGY

A Highly Conserved Motif within the NH2-terminal Coiled-coil Domain of Angiopoietin-like Protein 4 Confers Its Inhibitory Effects on Lipoprotein Lipase by Disrupting the Enzyme Dimerization

(2009) Ming-hon Yau et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipopolysaccharide (LPS) stimulates adipokine and socs3 gene expression in mouse brain and pituitary gland in vivo, and in N-1 hypothalamic neurons in vitro

(2009) Russell Brown et al.   JOURNAL OF NEUROIMMUNOLOGY

Suppression of the Raf/MEK/ERK Signaling Cascade and Inhibition of Angiogenesis by the Carboxyl Terminus of Angiopoietin-Like Protein 4

(2008) Ying-Hua Yang et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Overexpression of Interleukin-1β in the Murine Pancreas Results in Chronic Pancreatitis

(2008) Frederic Marrache et al.   GASTROENTEROLOGY

The calcium binding protein S100A9 is essential for pancreatic leukocyte infiltration and induces disruption of cell–cell contacts

(2008) Jürgen Schnekenburger et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Selective contribution of interleukin-6 and leptin to brain inflammatory signals induced by systemic LPS injection in mice

(2008) Christoph Rummel et al.   JOURNAL OF COMPARATIVE NEUROLOGY

The Role of Angiopoietin-Like Proteins in Angiogenesis and Metabolism

(2008) Tai Hato et al.   TRENDS IN CARDIOVASCULAR MEDICINE