Knockout of vascular smooth muscle EGF receptor in a mouse model prevents obesity-induced vascular dysfunction and renal damage in vivo

Diabetes, Hypertension, and Cardiovascular Disease: Clinical Insights and Vascular Mechanisms

(2018) John R. Petrie et al.   CANADIAN JOURNAL OF CARDIOLOGY

Obesity and kidney disease: from population to basic science and the search for new therapeutic targets

(2017) Adam Whaley-Connell et al.   KIDNEY INTERNATIONAL

Long Term High Fat Diet Treatment: An Appropriate Approach to Study the Sex-Specificity of the Autonomic and Cardiovascular Responses to Obesity in Mice

(2017) Thiago Bruder-Nascimento et al.   Frontiers in Physiology

Epidermal Growth Factor Receptor Transactivation: Mechanisms, Pathophysiology, and Potential Therapies in the Cardiovascular System

(2016) Steven J. Forrester et al.   Annual Review of Pharmacology and Toxicology

Emerging roles of the myocardin family of proteins in lipid and glucose metabolism

(2016) Karl Swärd et al.   JOURNAL OF PHYSIOLOGY-LONDON

Challenging the dogma of mitochondrial reactive oxygen species overproduction in diabetic kidney disease

(2016) Melinda T. Coughlan et al.   KIDNEY INTERNATIONAL

g:Profiler—a web server for functional interpretation of gene lists (2016 update)

(2016) Jüri Reimand et al.   NUCLEIC ACIDS RESEARCH

Acidic environment activates inflammatory programs in fibroblasts via a cAMP–MAPK pathway

(2015) A. Riemann et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Consequences of postnatal vascular smooth muscle EGFR deletion on acute angiotensin II action

(2015) B. Schreier et al.   CLINICAL SCIENCE

Epidermal Growth Factor Receptor Is Critical For Angiotensin II-Mediated Hypertrophy in Cerebral Arterioles

(2015) S.-L. Chan et al.   HYPERTENSION

Role of Epidermal Growth Factor Receptor and Endoplasmic Reticulum Stress in Vascular Remodeling Induced by Angiotensin IINovelty and Significance

(2015) Takehiko Takayanagi et al.   HYPERTENSION

High Glucose Up-regulates ADAM17 through HIF-1α in Mesangial Cells

(2015) Renzhong Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Elevated Glucose Levels Promote Contractile and Cytoskeletal Gene Expression in Vascular Smooth Muscle via Rho/Protein Kinase C and Actin Polymerization

(2015) Tran Thi Hien et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The dual targeting of EGFR and ErbB2 with the inhibitor Lapatinib corrects high glucose-induced apoptosis and vascular dysfunction by opposing multiple diabetes-induced signaling changes

(2015) Ibrahim F. Benter et al.   JOURNAL OF DRUG TARGETING

G-protein-mediated signaling in vascular smooth muscle cells — implications for vascular disease

(2015) Till F. Althoff et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Macrophages in Kidney Injury, Inflammation, and Fibrosis

(2015) Qi Cao et al.   PHYSIOLOGY

A conserved MADS-box phosphorylation motif regulates differentiation and mitochondrial function in skeletal, cardiac and smooth muscle cells

(2015) W Mughal et al.   Cell Death & Disease

Role of epidermal growth factor receptor in vascular structure and function

(2014) Barbara Schreier et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Dual views of SRF: a genomic exposure

(2014) K. A. Clark et al.   GENES & DEVELOPMENT

Free Fatty Acids Shift Insulin-induced Hepatocyte Proliferation towards CD95-dependent Apoptosis

(2014) Annika Sommerfeld et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The pathobiology of diabetic vascular complications—cardiovascular and kidney disease

(2014) Stephen P. Gray et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

Regulator of G-Protein Signaling 5 Controls Blood Pressure Homeostasis and Vessel Wall Remodeling

(2013) Vasyl Holobotovskyy et al.   CIRCULATION RESEARCH

The Epidermal Growth Factor Receptor and Its Ligands in Cardiovascular Disease

(2013) Nader Makki et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The role of the glomerular endothelium in albumin handling

(2013) Simon Satchell   Nature Reviews Nephrology

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions

(2013) Daehwan Kim et al.   GENOME BIOLOGY

The Role of Tissue Renin-Angiotensin-Aldosterone System in the Development of Endothelial Dysfunction and Arterial Stiffness

(2013) Annayya R. Aroor et al.   Frontiers in Endocrinology

The Epidermal Growth Factor Receptor

(2012) Tomonori Kobayashi et al.   HYPERTENSION

Loss of Epidermal Growth Factor Receptor in Vascular Smooth Muscle Cells and Cardiomyocytes Causes Arterial Hypotension and Cardiac Hypertrophy

(2012) Barbara Schreier et al.   HYPERTENSION

Serum Response Factor (SRF)-cofilin-actin signaling axis modulates mitochondrial dynamics

(2012) H. Beck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PDGF-dependent regulation of regulator of G protein signaling-5 expression and vascular smooth muscle cell functionality

(2011) Jagadambika J. Gunaje et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

A Glimpse of Various Pathogenetic Mechanisms of Diabetic Nephropathy

(2011) Yashpal S. Kanwar et al.   Annual Review of Pathology-Mechanisms of Disease

Renal Function in Diabetic Disease Models: The Tubular System in the Pathophysiology of the Diabetic Kidney

(2011) Volker Vallon et al.   Annual Review of Physiology

Consequences of Epidermal Growth Factor Receptor (ErbB1) Loss for Vascular Smooth Muscle Cells From Mice With Targeted Deletion of ErbB1

(2011) Barbara Schreier et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Aldosterone/NaCl-induced renal and cardiac fibrosis is modulated by TGF-β responsiveness of T cells

(2011) Barbara Schreier et al.   HYPERTENSION RESEARCH

Increased SRF transcriptional activity in human and mouse skeletal muscle is a signature of insulin resistance

(2011) Wanzhu Jin et al.   JOURNAL OF CLINICAL INVESTIGATION

EGFR Signaling Promotes TGF -Dependent Renal Fibrosis

(2011) J. Chen et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

α1-Adrenoceptor-mediated contraction of rat aorta is partly mediated via transactivation of the epidermal growth factor receptor

(2010) N Ulu et al.   BRITISH JOURNAL OF PHARMACOLOGY

Oxidative stress and inflammatory mediators contribute to endothelial dysfunction in high-fat diet-induced obesity in mice

(2010) Renata Kobayasi et al.   JOURNAL OF HYPERTENSION

Linking actin dynamics and gene transcription to drive cellular motile functions

(2010) Eric N. Olson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists

(2009) Eran Eden et al.   BMC BIOINFORMATICS

Puerarin attenuates high-glucose-and diabetes-induced vascular smooth muscle cell proliferation by blocking PKCβ2/Rac1-dependent signaling

(2009) Li-Hua Zhu et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mapping identifiers for the integration of genomic datasets with the R/Bioconductor package biomaRt

(2009) Steffen Durinck et al.   Nature Protocols

Pscan: finding over-represented transcription factor binding site motifs in sequences from co-regulated or co-expressed genes

(2009) Federico Zambelli et al.   NUCLEIC ACIDS RESEARCH

Early inhibition of EGFR signaling prevents diabetes-induced up-regulation of multiple gene pathways in the mesenteric vasculature

(2009) Ibrahim F. Benter et al.   VASCULAR PHARMACOLOGY

Ultrafast and memory-efficient alignment of short DNA sequences to the human genome

(2009) Ben Langmead et al.   GENOME BIOLOGY

Elevated Epidermal Growth Factor Receptor Phosphorylation Induces Resistance Artery Dysfunction in Diabetic db/db Mice

(2008) S. Belmadani et al.   DIABETES

Deletion of Transient Receptor Potential Vanilloid Type 1 Receptors Exaggerates Renal Damage in Deoxycorticosterone Acetate-Salt Hypertension

(2008) Youping Wang et al.   HYPERTENSION

RGS5, RGS4, and RGS2 expression and aortic contractibility are dynamically co-regulated during aortic banding-induced hypertrophy

(2008) Xi Wang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY