Article
Neurosciences
Yihui Zhang, Jianfeng Zhang, Musi Xie, Nai Ding, Yang Zhang, Pengmin Qin
Summary: Heartbeat-evoked responses (HERs) interact with external stimuli and play a crucial role in shaping perception, self-related processes, and emotional processes. The study investigates the interactive mechanism between HERs and the perception of one's own name (SON), demonstrating that HERs can be modulated by SON and can also bias the judgment of SON.
Article
Neurosciences
Mengli Chang, Yuxin Lei, Jing Zhang, Jing Xu, Hongwei Wu, Shihuan Tang, Hongjun Yang
Summary: Neuroinflammation caused by microglia in the central nervous system (CNS) is observed after myocardial infarction (MI). However, the mechanism of the inflammatory response remains unclear. This study investigated the pharmacodynamic mechanism of BuChang Naoxintong capsule (NXT) in treating MI. The results showed that NXT demonstrated a better pharmacodynamic action towards myocardial injury and neuroinflammation. Proteomics analysis identified ELOVL5 and ABCG4 as critical proteins associated with MI and neuroinflammation. The study also found that ABCG4 had a good binding ability with the key ingredients of NXT, and its expression and structure were affected by brain neuroinflammation induced by microglia after MI.
MOLECULAR NEUROBIOLOGY
(2023)
Article
Clinical Neurology
Regina von Rennenberg, Thomas Krause, Juliane Herm, Simon Hellwig, Jan F. Scheitz, Matthias Endres, Karl Georg Haeusler, Christian H. Nolte
Summary: The study found no significant association between heart rate variability in the acute phase of ischemic stroke and subsequent recurrent stroke, myocardial infarction, death, or functional outcomes. Therefore, HRV may not be a reliable predictor of vascular events in patients with mild to moderate ischemic stroke.
FRONTIERS IN NEUROLOGY
(2021)
Article
Gastroenterology & Hepatology
Chun Chen, Jianming Liao, Yiyuan Xia, Xia Liu, Rheinallt Jones, John Haran, Beth McCormick, Timothy Robert Sampson, Ashfaqul Alam, Keqiang Ye
Summary: This study investigates the role of gut dysbiosis in triggering brain inflammation and its contribution to AD pathogenesis. The results show that AD patients' gut microbiome exacerbates AD pathologies in a mouse model and is associated with cognitive dysfunction.
Article
Multidisciplinary Sciences
Andrea Duggento, Maria Guerrisi, Nicola Toschi
Summary: This article introduces a GC framework based on echo-state networks for capturing nonlinear causal relationships, showing advantages in detecting nonlinear causal links in noisy Duffing oscillators networks. Additionally, it reveals unknown directed within-brain interactions in the human brain using functional MRI data and explores the relationship between brain networks and central vagal cardiac control.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES
(2021)
Article
Environmental Sciences
Meixian Wang, Yan Tian, Ping Yu, Nana Li, Ying Deng, Lu Li, Hong Kang, Dapeng Chen, Hui Wang, Zhen Liu, Juan Liang
Summary: The study revealed a correlation between maternal manganese and iron concentrations and the risk of CHD among infants, with a potential higher risk associated with concurrent high levels of manganese and iron. Excessive manganese concentration in pregnant women was linked to a significantly increased risk of CHDs. Additionally, high maternal iron status was also found to correlate with CHDs, but no interaction between maternal manganese and iron concentrations was observed in the study.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2022)
Article
Neurosciences
Junjun Li, Ying Liu, Yi Wang, Nizhuan Wang, Yuzhu Ji, Tongqi Wei, Hong-Yan Bi, Yang Yang
Summary: This study examined the neural mechanisms underlying the relationship between central and peripheral processes in handwriting. The results showed that central processing affects peripheral processing, and there is a complex neural interaction between central and peripheral processes.
HUMAN BRAIN MAPPING
(2023)
Article
Clinical Neurology
Hideomi Hamasaki, Masahiro Shijo, Ayaka Nakamura, Hiroyuki Honda, Yuichi Yamada, Masanao Oda, Tomoyuki Ohara, Toshiharu Ninomiya, Toru Iwaki
Summary: This study investigated the relationship between degenerative changes of the brain and heart, with reference to AD pathologies, ATTR deposition, and cardiac fibrosis in a Japanese population. It found that cardiac ATTR deposition correlated with AD brain pathology among older adults aged 90 or below.
Article
Neurosciences
Jo-Fu Lotus Lin, Toshiaki Imada, Andrew N. Meltzoff, Hirotoshi Hiraishi, Takashi Ikeda, Tetsuya Takahashi, Chiaki Hasegawa, Yuko Yoshimura, Mitsuru Kikuchi, Masayuki Hirata, Yoshio Minabe, Minoru Asada, Patricia K. Kuhl
Summary: Verbal interaction and imitation are crucial for language learning and development in young children. This study utilized a dual-MEG setup to investigate the neural synchrony between mother-child pairs during turn-taking verbal interactions. The findings revealed increased interbrain synchronization in socially interactive tasks compared to noninteractive tasks, particularly in the theta and alpha bands. Specific parietal and frontal regions were identified as cortical hubs exhibiting a high number of interbrain connections, which may serve as neural markers for the interactive component in verbal social communication.
Article
Biochemistry & Molecular Biology
Weixue Xiong, Jiahui Cai, Bo Sun, Henghui Lin, Chiyu Wei, Chengcheng Huang, Xiaohui Zhu, Haizhu Tan
Summary: Alzheimer's disease (AD) is a highly heritable disease that affects morphology-based brain networks, leading to functional deficits. This study examines the effect of genetic variations on brain networks and explores the protein-protein interaction (PPI) between candidate proteins and known AD-related proteins. Genetic variations were analyzed in AD patients and healthy controls, and eight genes affecting morphology-based brain networks were identified. Molecular dynamics simulation and co-immunoprecipitation experiments verified the strong PPI between TGM4 and BACE1, suggesting that gene variations influence morphology-based brain networks in AD.
JOURNAL OF NEUROCHEMISTRY
(2023)
Article
Multidisciplinary Sciences
Viktor Mueller, Ulman Lindenberger
Summary: This study explores the association between interbrain synchronization and interpersonal action coordination by analyzing the brain activity of guitarists in a duet and the acoustic recordings of their music. The results show that synchronous brain activity is strongly related to instrument sounds and behavioral play-onset synchrony, especially in the first part of the music piece. This suggests that capturing intra- and interbrain synchronization provides crucial information about the underlying mechanisms of interpersonal action coordination.
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES
(2022)
Review
Food Science & Technology
Siyu Liu, Lu Cheng, Yanan Liu, Shengnan Zhan, Zufang Wu, Xin Zhang
Summary: Cognitive, mood, and sleep disorders are common and difficult to treat central nervous system disorders that significantly impact the lives of affected individuals. The gut-brain axis, which facilitates bidirectional information exchange between the gut microbiota and the nervous system, plays a vital role in the study of neurological disorders like neurodegenerative diseases. Dietary polyphenols have garnered attention due to their biological activity, diverse sources, structural variability, and low toxicity. Increasing the intake of dietary polyphenols is an emerging strategy for improving circadian rhythms and treating metabolic disorders by modulating the gut-brain axis.
Article
Clinical Neurology
Yumin Zhu, Xian Chen, Lizhe Guo, Lu Wang, Na Chen, Yujie Xiao, E. Wang
Summary: This study suggests that acute sleep deprivation worsens left heart function in patients with heart failure and leads to increased levels of inflammatory cytokines.
JOURNAL OF SLEEP RESEARCH
(2022)
Article
Medicine, General & Internal
Wojciech Dabrowski, Dorota Siwicka-Gieroba, Todd T. Schlegel, Chiara Robba, Sami Zaid, Magdalena Bielacz, Andrzej Jaroszynski, Rafael Badenes
Summary: In patients with traumatic brain injury (TBI), QTc interval prolongation occurs during ESz events but improves after the seizures are suppressed, along with an increase in regional cerebral oximetry levels.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Neurosciences
Xiao-Juan Xue, Rui Su, Ze-Feng Li, Xiao-Ou Bu, Peng Dang, Si-Fang Yu, Zhi-Xin Wang, Dong-Mei Chen, Tong-Ao Zeng, Ming Liu, Hai-Lin Ma, De-Long Zhang
Summary: Neurophysiological pathways of heart-brain interaction were identified based on the relationship between oxygen-transport by red blood cells (RBCs) and consciousness/attention. The findings showed that RBC function triggered interoceptive re-representations and immune responses, affecting consciousness and executive control. Consciousness played a fundamental role in executive function and may be associated with perceived stress levels.
NEUROSCIENCE BULLETIN
(2022)
