期刊
CIRCULATION JOURNAL
卷 80, 期 6, 页码 1300-1307出版社
JAPANESE CIRCULATION SOC
DOI: 10.1253/circj.CJ-16-0353
关键词
Congenital heart disease; Extracellular volume fraction; Late gadolinium enhancement; Magnetic resonance imaging; Myocardial fibrosis
Myocardial fibrosis is common in patients with congenital heart disease (CHD) and has been associated with arrhythmias, decreased functional status, and adverse ventricular mechanics. There are multiple types of myocardial fibrosis that occur in response to different pathophysiologic stimuli. Recent advances in imaging technology have made detection and quantification of the types of myocardial fibrosis possible. In this review, we describe the pathophysiology of myocardial fibrosis, examine the imaging techniques used to evaluate fibrosis, and discuss the relationship between myocardial fibrosis and clinical outcomes in CHD.
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