Review
Cardiac & Cardiovascular Systems
Daniela Crousillat, Joan Briller, Niti Aggarwal, Leslie Cho, Thais Coutinho, Colleen Harrington, Eric Isselbacher, Kathryn Lindley, Maral Ouzounian, Ourania Preventza, Jyoti Sharma, Ranya Sweis, Melissa Russo, Nandita Scott, Nupoor Narula
Summary: Despite being more common in men, women with thoracic aortic aneurysm and dissection (TAAD) receive lower rates of treatment and surgical intervention, leading to worse outcomes. Additionally, an increasing number of women with TAAD desire pregnancy, which poses an increased risk of aortic complications. Understanding the sex-specific differences in TAAD holds the potential to enhance care delivery, reduce treatment disparities, and optimize outcomes for women with TAAD.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Medicine, General & Internal
Tomasz Plonek, Bartosz Rylski, Pawel Nawrocki, Friedhelm Beyersdorf, Marek Jasinski, Wiktor Kuliczkowski
Summary: The study demonstrates a negative correlation between systolic aortic stretching and patient age and the diameter of the tubular ascending aorta, but not with the diameter of the aortic root. Additionally, systolic aortic stretching values were lower in patients with aortic valve pathology.
ARCHIVES OF MEDICAL SCIENCE
(2021)
Article
Medicine, General & Internal
Nerea Lopez Perez, Philippe Reymond, Mustafa Cikirikcioglu, Mathieu van Steenberghe, Tornike Sologashvili, Nicolas Murith, Thomas Perneger, Christoph Huber
Summary: This study examines the ratio between ascending and descending aorta diameters as a potential surrogate marker for decision making in cases of ascending aortic dilatation. A retrospective observational cohort study was conducted on 50 patients who underwent surgery for acute type A aorta dissection. The results suggest that the ratio between descending and ascending aorta diameters may be a useful tool for stratifying the risk of dissection.
JOURNAL OF CLINICAL MEDICINE
(2023)
Review
Surgery
Marethania M. Akmal, Dara R. Pabittei, Tossapol Prapassaro, Raden Suhartono, Frans L. Moll, Joost A. van Herwaarden
Summary: The study systematically reviewed different techniques for excluding persistent type II endoleaks after EVAR, showing a wide variety of techniques and embolic agents used. Despite varying technical success rates, the overall technical success rate was 62%. Further studies with longer follow-up are urgently needed to determine the most effective treatment for a durable exclusion of persistent type II endoleaks.
INTERNATIONAL JOURNAL OF SURGERY
(2021)
Article
Cardiac & Cardiovascular Systems
Christopher Lau, Giovanni Soletti, Jonathan W. Weinsaft, Mohamed Rahouma, Talal Al Zghari, Roberto Perezgrovas Olaria, Lamia Harik, Mohammad Yaghmour, Arnaldo Dimagli, Mario Gaudino, Leonard N. Girardi
Summary: This study compared operative and long-term outcomes between patients with and without Marfan syndrome undergoing thoracoabdominal aortic aneurysm repair. The study found that patients with and without Marfan syndrome had similar operative outcomes despite differing risk profiles.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
(2023)
Article
Medicine, General & Internal
Constantin Bonorden, Mohamed Shoura, Mateja Andic, Julia Kelley Hahn, Migdat Mustafi, Christian Schlensak, Mario Lescan
Summary: The study aimed to assess the mid-term results of the E-iliac branched device for the treatment of aortoiliac aneurysms. The results showed high technical success and low re-intervention rate, indicating promising mid-term outcomes for E-iliac.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Angela Lopez-Sainz, Laia Mila, Jose Rodriguez-Palomares, Javier Limeres, Chiara Granato, Lucia La Mura, Ana Sabate, Andrea Guala, Laura Gutierrez, Laura Galian-Gay, Augusto Sao-Aviles, Sergi Bellmunt, Rafael Rodriguez, Hug Cuellar-Calabria, Albert Roque, Ignacio Ferreira-Gonzalez, Artur Evangelista, Gisela Teixido-Tura
Summary: This study revealed that aortic branch aneurysms are present in approximately one-quarter of patients with MFS, are associated with patient age and aortic dilation, and independently predict the need for aortic surgery.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Article
Medicine, General & Internal
Maria Fernanda Cassino Portugal, Marcelo Passos Teivelis, Marcelo Fiorelli Alexandrino da Silva, Alexandre Fioranelli, Claudia Szlejf, Edson Amaro-Junior, Nelson Wolosker
Summary: The study analyzed endovascular treatment of isolated descending thoracic aortic disease cases in the Brazilian public health system and found that elective procedures were associated with lower mortality than urgent procedures. There was no statistically significant difference between elective and urgent procedures regarding costs.
Article
Medicine, General & Internal
Maria Fernanda Cassino Portugal, Marcelo Passos Teivelis, Marcelo Fiorelli Alexandrino da Silva, Nickolas Stabellini, Alexandre Fioranelli, Claudia Szlejf, Edson Amaro Junior, Nelson Wolosker
Summary: A study on endovascular treatment of isolated thoracic aorta disease in Sao Paulo, Brazil over a 10-year period showed that most patients were male, aged 65 and above, with approximately one-third of surgeries being urgent cases. Urgent surgeries had higher in-hospital mortality and costs compared to elective procedures.
Article
Peripheral Vascular Disease
Raul R. Rodrigues-Diez, Antonio Tejera-Munoz, Vanesa Esteban, Lasse B. Steffensen, Raquel Rodrigues-Diez, Macarena Orejudo, Sandra Rayego-Mateos, Lucas L. Falke, Pablo Cannata-Ortiz, Alberto Ortiz, Jesus Egido, Ziad Mallat, M. Briones Ana, M. Auxiliadora Bajo, Roel Goldschmeding, Marta Ruiz-Ortega
Summary: This study reveals the critical involvement of CCN2 in the homeostasis and response to vascular injury of the aorta, particularly under Ang II-induced stress. CCN2 deletion leads to rapid development and rupture of aortic aneurysms, with the maintenance of aortic integrity partially dependent on the aldosterone pathway.
Article
Genetics & Heredity
David Freiholtz, Otto Bergman, Sailendra Pradhananga, Karin Lang, Flore-Anne Poujade, Carl Granath, Christian Olsson, Anders Franco-Cereceda, Pelin Sahlen, Per Eriksson, Hanna M. Bjorck
Summary: The fibrotic type of endothelial mesenchymal transition (EndMT) is implicated in the development of degenerative ascending aortic aneurysm (AscAA). This study identified SPP1 as a key gene in the signature of fibrotic EndMT in patients with degenerative AscAA. The study also implicated ETS1 as a potential regulator of SPP1 expression under inflammatory conditions.
JOURNAL OF MOLECULAR MEDICINE-JMM
(2023)
Article
Surgery
David J. Laczynski, Siwei Dong, Vidyasagar Kalahasti, Levester Kirksey, Jarrad W. Rowse, Jon G. Quatromoni, Sean P. Lyden, Francis J. Caputo
Summary: This study evaluated the prevalence of intracranial aneurysms (IA) in patients with Marfan syndrome (MFS) who underwent intracranial imaging, and found a prevalence rate of 7.1%. There were no significant associations between age, aortic characteristics, and the occurrence of IA, but this finding may be limited by the small number of aneurysms.
JOURNAL OF VASCULAR SURGERY
(2023)
Article
Surgery
Owen S. Glotzer, Gabrielle Rieth, Amanda Kistler, Jeffrey Hnath, Edward Gifford, Clement Darling III
Summary: The right retroperitoneal approach to the aorta is a useful technique in patients with prior surgery, anatomical abnormalities, or infection that complicates the use of other approaches. This study demonstrates comparable outcomes and technical feasibility, suggesting that the right retroperitoneal approach can be considered as a viable alternative to other traditional access methods in patients with complex anatomy or prohibitive pathology.
JOURNAL OF VASCULAR SURGERY
(2023)
Article
Surgery
Kelli L. Summers, Edmund K. Kerut, Claudie M. Sheahan, Malachi G. Sheahan
Summary: This study analyzed data from a large-scale AAA screening program in the United States and found that male gender, smoking, cardiac disease, family history, and advancing age are high-risk factors for AAA. Current smoking status was the most significant risk factor.
JOURNAL OF VASCULAR SURGERY
(2021)
Article
Surgery
J. Michael Cullen, Alexander H. Shannon, Guanyi Lu, Gang Su, Michael D. Spinosa, William G. Montgomery, Gorav Ailawadi, Morgan Salmon, Gilbert R. Upchurch
Summary: The study on swine experiments revealed that female pigs have a higher dilation rate in forming abdominal aortic aneurysms, while uncastrated male pigs exhibit larger aneurysm size and elastin degradation.
JOURNAL OF SURGICAL RESEARCH
(2021)