Article
Health Care Sciences & Services
Aikaterini Vraka, Vicente Bertomeu-Gonzalez, Lorenzo Facila, Jose Moreno-Arribas, Raul Alcaraz, Jose J. Rieta
Summary: This study analyzes the crucial steps of coronary sinus catheterization and left and right pulmonary veins isolation in pulmonary veins catheter ablation for atrial fibrillation. The results show that P-waves are more affected than local activation waves by the ablation process, and LPVI has the most significant impact on P-wave duration.
JOURNAL OF PERSONALIZED MEDICINE
(2022)
Review
Cardiac & Cardiovascular Systems
Dan Qi, Jianjun Zhang
Summary: This study investigated the potential relationship between anatomical characteristics of pulmonary veins (PVs) and atrial fibrillation recurrence (AFR) following radiofrequency catheter ablation (RFCA). The results showed that patients with AFR had a significantly larger mean PV diameter compared to those without AFR. This suggests that PV diameter could serve as a potential predictor of the risk of AFR following RFCA.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Tristram D. Bahnson, Anna Giczewska, Daniel B. Mark, Andrea M. Russo, Kristi H. Monahan, Hussein R. Al-Khalidi, Adam P. Silverstein, Jeanne E. Poole, Kerry L. Lee, Douglas L. Packer
Summary: According to the CABANA trial, catheter ablation is most effective in younger patients, while no prognostic benefits were observed in the oldest patients. Catheter ablation is more effective than drug therapy in preventing atrial fibrillation recurrence, with few complications regardless of age.
Article
Cardiac & Cardiovascular Systems
Jonathan M. Kalman, Ahmed M. Al-Kaisey, Ramanathan Parameswaran, Joshua Hawson, Robert D. Anderson, Michael Lim, David Chieng, Stephen A. Joseph, Alex McLellan, Joseph B. Morton, Paul B. Sparks, Geoffrey Lee, Prashanthan Sanders, Peter M. Kistler
Summary: This study aimed to determine if the timing of catheter ablation for atrial fibrillation (AF) affects arrhythmia outcomes. The results showed that there was no significant difference in the atrial arrhythmia free survival at 12 months post-ablation between patients who underwent early ablation and those who underwent delayed ablation. Other secondary outcomes also showed no significant difference. Therefore, delaying AF ablation by 12 months for antiarrhythmic drug management does not reduce the efficacy of ablation.
EUROPEAN HEART JOURNAL
(2023)
Article
Cardiac & Cardiovascular Systems
Stepan Havranek, Zdenka Fingrova, Tomas Skala, Adrian Reichenbach, Milan Dusik, Pavel Jansa, David Ambroz, Vladimir Dytrych, Dalibor Klimes, Martin Hutyra, Josef Kautzner, Ales Linhart, Dan Wichterle
Summary: This study aimed to investigate whether more extensive radiofrequency catheter ablation of the bi-atrial arrhythmogenic substrate instead of clinical arrhythmia ablation alone results in superior clinical outcomes in patients with pulmonary arterial hypertension (PH) and supraventricular arrhythmias. The results showed similar arrhythmia recurrence rates between the two treatment groups, and no excess of procedural complications or clinical events in the extensive ablation group.
Article
Cardiac & Cardiovascular Systems
Andreas Metzner, Karl-Heinz Kuck, Julian K. R. Chun
Summary: Atrial fibrillation ablation is an important treatment option for symptomatic patients, with electrical isolation of the pulmonary veins as the cornerstone. The lack of persistent isolation limits the understanding of the impact on AF suppression, necessitating the development of novel ablation systems to improve success rates.
Article
Cardiac & Cardiovascular Systems
Daehoon Kim, Taehyun Hwang, Min Kim, Hee Tae Yu, Tae-Hoon Kim, Jae-Sun Uhm, Boyoung Joung, Moon-Hyoung Lee, Hui-Nam Pak
Summary: Extra-pulmonary vein triggers are commonly found in atrial fibrillation patients and associated with poorer rhythm outcomes after both de novo and repeat catheter ablation procedures.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Review
Cardiac & Cardiovascular Systems
Gianluigi Bisleri, Arjun K. Pandey, Subodh Verma, Syed M. Ali Hassan, Bobby Yanagawa, Masud Khandaker, Mario Gaudino, Andrea M. Russo, Atul Verma, Deepak L. Bhatt, Andrew C. T. Ha
Summary: Hybrid ablation is a novel therapy that combines minimally invasive surgical and percutaneous catheter-based techniques for the management of atrial fibrillation (AF). Observational studies have shown approximately 70% success rates but higher risks compared to catheter-based ablation. Hybrid ablation is typically offered to patients with persistent or longstanding persistent AF, requiring two procedures. While a randomized trial demonstrated its superiority over catheter-based ablation, it also showed higher complication rates. Contemporary studies have shown a decrease in the incidence of serious complications. Additional randomized trials are needed to determine the risks, benefits, and cost effectiveness of hybrid ablation in clinical practice.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Geoffroy Ditac, Pierre Jean Cottinet, Minh Quyen Le, Daniel Grinberg, Josselin Duchateau, Kevin Gardey, Arnaud Dulac, Antoine Deliniere, Christelle Haddad, Julie Boussuge-Roze, Frederic Sacher, Pierre Jais, Philippe Chevalier, Francis Bessiere
Summary: Atrial fibrillation (AF) catheter ablation procedure contributes significantly to GHG emissions, with a carbon footprint of 76.9 kg CO2-e. With approximately 600,000 annual procedures worldwide, AF catheter ablation leads to 125 tons of CO2 emissions every day, equivalent to a daily car ride of 700,000 km. Electrophysiology catheters and patches are identified as the main contributors to the carbon footprint, highlighting the importance of reducing, reusing, and recycling these items.
Article
Cardiac & Cardiovascular Systems
Yun Young Choi, Jong-Il Choi, Joo Hee Jeong, Hyoung Seok Lee, Yun Gi Kim, Mi-Na Kim, Seung-Young Roh, Jaemin Shim, Jin Seok Kim, Seong-Mi Park, Young-Hoon Kim
Summary: This study found that a higher pulmonary artery pressure (PAP) is associated with an increased risk of recurrence after radiofrequency catheter ablation in patients with paroxysmal atrial fibrillation, suggesting a mechanism by which pulmonary vascular dysfunction may lead to pulmonary vein impairment and left atrial remodeling.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Karim Benali, Paul Khairy, Nefissa Hammache, Adrian Petzl, Antoine Da Costa, Atul Verma, Jason G. Andrade, Laurent Macle
Summary: A systematic review and pooled analysis of randomized control trials showed that catheter ablation of atrial fibrillation is associated with low rates of procedure-related complications and mortality, which have declined over the past decade.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Andrei Alexandru Mircea, Mihaela Rusu, Elisa Anamaria Liehn, Octavian Bucur
Summary: This review focuses on newly developed strategies, such as vernakalant and stereotactic ablative therapy, for the treatment of arrhythmias. These therapies are important for improving the management of atrial fibrillation and ventricular tachycardia, offering higher success rates and lower costs.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Biology
Chunying Jiang, Jun Zhang, Zhongyuan Ren, Rong Guo, Hailing Li, Shuang Li, Mengyun Zhu, Peng Jia, Kai Tang, Dongdong Zhao, Yawei Xu
Summary: This study analyzed data from 29 patients with recurrent AF undergoing repeat RF ablation, finding a higher incidence of conduction gaps and reconnection in the right superior pulmonary vein during cryoablation. Strategies such as close touch of CB on specific segments of RSPV may help achieve durable PV isolation during follow-up.
Article
Cardiac & Cardiovascular Systems
Elena Arbelo, Nikolaos Dagres
Summary: This article critically reviews the recommendations of the 2020 ESC guidelines for the management of AF in light of two landmark trials, emphasizing the safety of contemporary rhythm control treatment and the importance of personalized treatment strategies.
Article
Physiology
Jae-Hyuk Lee, Oh-Seok Kwon, Hee Tae Yu, Tae-Hoon Kim, Jae-Sun Uhm, Boyoung Joung, Moon-Hyoung Lee, Hui-Nam Pak
Summary: Catheter ablation is an effective method for treating atrial fibrillation, but it may lead to atrial tissue damage and increase the risk of stiff LA physiology. Factors such as diabetes, E/Em ratio, LA pulse pressure, low LA voltage, empirical extra-PV ablation, and radiofrequency ablation duration are associated with stiff LA physiology after AFCA.
FRONTIERS IN PHYSIOLOGY
(2021)